• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Gog-2668

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: V-type proton ATPase subunit C
Ensembl Gene: ENSGGOG00000004146.3
Ensembl Protein: ENSGGOP00000004068.2
Organism: Gorilla gorilla
Taxa ID: 9595
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Postsynaptic densityPredicted from orthologs(View)

▼ FUNCTION

Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MTEFWLISAP  GEKTCQQTWE  KLHAATSKNN  NLAVTSKFNI  PDLKVGTLDV  LVGLSDELAK  60
61    LDAFVEGVVK  KVAQYMADVL  EDSKDKVQEN  LLANGVDLVT  YITRFQWDMA  KYPIKQSLKN  120
121   ISEIIAKGVT  QIDNDLKSRA  SAYNNLKGNL  QNLERKNAGS  LLTRSLAEIV  KKDDFVLDSE  180
181   YLVTLLVVVP  KLNHNDWIKQ  YETLAEMVVP  RSSNVLSEDQ  DSYLCNVTLF  RKAVDDFRHK  240
241   ARENKFIVRD  FQYNEEEMKA  DKEEMNRLST  DKKKQFGPLV  RWLKVNFSEA  FIAWIHVKAL  300
301   RVFVESVLRY  GLPVNFQAML  LQPNKKTLKK  LREVLHELYK  HLDSSAAAII  DAPMDIPGLN  360
361   LSQQEYYPYV  YYKIDCNLLE  FK  382
Nucleotide CDS Sequence (FASTA)
1     ATGACTGAGT  TCTGGCTTAT  ATCTGCTCCT  GGGGAGAAAA  CCTGTCAGCA  AACATGGGAG  60
61    AAATTGCATG  CGGCAACTTC  AAAGAACAAT  AATCTTGCTG  TCACTTCCAA  GTTCAATATT  120
121   CCTGACTTAA  AGGTTGGCAC  GTTGGATGTC  TTGGTTGGCT  TGTCAGATGA  ACTGGCTAAA  180
181   CTGGATGCAT  TTGTAGAAGG  AGTGGTTAAG  AAAGTAGCTC  AATACATGGC  TGATGTATTG  240
241   GAAGATAGCA  AAGACAAAGT  TCAAGAGAAT  CTGTTGGCTA  ATGGAGTGGA  CTTGGTTACT  300
301   TATATAACAA  GGTTCCAGTG  GGACATGGCC  AAATATCCAA  TCAAGCAGTC  CCTGAAAAAT  360
361   ATTTCTGAAA  TAATTGCCAA  GGGAGTAACT  CAGATTGATA  ATGACCTGAA  ATCTCGCGCA  420
421   TCTGCATACA  ATAACCTGAA  AGGAAATCTT  CAGAATTTGG  AACGAAAGAA  TGCAGGAAGT  480
481   TTGCTAACTA  GAAGTCTAGC  AGAAATTGTG  AAGAAGGATG  ACTTTGTTCT  TGATTCAGAG  540
541   TATCTCGTCA  CATTACTGGT  AGTAGTTCCC  AAGTTAAACC  ACAACGACTG  GATTAAGCAG  600
601   TATGAAACAC  TAGCCGAAAT  GGTAGTTCCA  AGGTCTAGCA  ATGTTCTTTC  AGAGGACCAA  660
661   GACAGTTACC  TGTGTAATGT  CACCTTGTTT  AGGAAGGCAG  TTGATGACTT  CAGACACAAA  720
721   GCCAGAGAAA  ACAAATTCAT  TGTTCGTGAC  TTCCAGTATA  ATGAAGAGGA  GATGAAAGCA  780
781   GATAAAGAAG  AAATGAACAG  GCTTTCCACT  GATAAGAAAA  AACAATTTGG  ACCACTTGTA  840
841   CGGTGGCTGA  AAGTGAATTT  TAGTGAAGCA  TTTATTGCAT  GGATTCACGT  GAAAGCATTA  900
901   CGGGTTTTCG  TTGAGTCTGT  TTTAAGGTAT  GGCTTGCCAG  TGAACTTCCA  AGCAATGCTA  960
961   CTTCAGCCCA  ATAAGAAAAC  TTTGAAGAAA  CTGAGAGAAG  TATTACATGA  ATTGTATAAA  1020
1021  CATCTAGACA  GCAGTGCAGC  AGCTATTATT  GATGCTCCTA  TGGATATTCC  AGGTTTAAAC  1080
1081  CTGAGTCAAC  AAGAATACTA  CCCCTATGTG  TACTACAAGA  TTGATTGCAA  CTTGCTGGAA  1140
1141  TTCAAGTGA  1149

▼ KEYWORD

ID
Family
Coiled coil
Complete proteome
Hydrogen ion transport
Ion transport
Reference proteome
Transport

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Plasma membrane
Cellular Component
Vacuolar proton-transporting V-type ATPase, V1 domain
Molecular Function
Proton-exporting ATPase activity, phosphorylative mechanism
Molecular Function
Proton-transporting ATPase activity, rotational mechanism
Biological Process
ATP hydrolysis coupled proton transport

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Man-4571Macaca nemestrina100.00.0 760
LLPS-Hos-4579Homo sapiens100.00.0 760
LLPS-Pap-2295Pan paniscus100.00.0 760
LLPS-Pat-3847Pan troglodytes100.00.0 760
LLPS-Rhb-0058Rhinopithecus bieti100.00.0 760
LLPS-Mam-0584Macaca mulatta100.00.0 760
LLPS-Nol-1484Nomascus leucogenys100.00.0 760
LLPS-Cea-4702Cercocebus atys100.00.0 760
LLPS-Maf-2095Macaca fascicularis100.00.0 760
LLPS-Chs-3879Chlorocebus sabaeus100.00.0 760
LLPS-Mal-3177Mandrillus leucophaeus100.00.0 760
LLPS-Paa-3482Papio anubis100.00.0 760
LLPS-Orc-2428Oryctolagus cuniculus99.480.0 759
LLPS-Aon-3824Aotus nancymaae99.480.0 759
LLPS-Caf-3992Canis familiaris99.210.0 756
LLPS-Cas-1110Carlito syrichta99.210.0 757
LLPS-Caj-1361Callithrix jacchus99.210.0 756
LLPS-Ova-2472Ovis aries99.210.0 757
LLPS-Fec-0332Felis catus98.950.0 755
LLPS-Dio-0645Dipodomys ordii98.950.0 755
LLPS-Bot-1577Bos taurus98.950.0 756
LLPS-Mup-1310Mustela putorius furo98.950.0 756
LLPS-Urm-1846Ursus maritimus98.690.0 754
LLPS-Ict-4185Ictidomys tridecemlineatus98.690.0 754
LLPS-Loa-0654Loxodonta africana98.430.0 748
LLPS-Otg-1354Otolemur garnettii98.430.0 754
LLPS-Sus-4663Sus scrofa98.430.0 753
LLPS-Tut-1293Tursiops truncatus98.430.0 741
LLPS-Aim-3325Ailuropoda melanoleuca98.430.0 753
LLPS-Poa-3076Pongo abelii98.170.0 746
LLPS-Eqc-4167Equus caballus98.170.0 753
LLPS-Mum-3218Mus musculus98.170.0 752
LLPS-Ran-3977Rattus norvegicus97.910.0 751
LLPS-Fud-3877Fukomys damarensis97.640.0 751
LLPS-Cap-2864Cavia porcellus97.120.0 744
LLPS-Ora-2618Ornithorhynchus anatinus96.070.0 736
LLPS-Meg-3324Meleagris gallopavo94.50.0 725
LLPS-Fia-1998Ficedula albicollis94.50.0 725
LLPS-Gaga-3678Gallus gallus94.50.0 725
LLPS-Sah-3456Sarcophilus harrisii94.50.0 734
LLPS-Pes-3521Pelodiscus sinensis94.240.0 728
LLPS-Anc-3134Anolis carolinensis93.980.0 724
LLPS-Pof-3104Poecilia formosa88.740.0 683
LLPS-Scm-1548Scophthalmus maximus88.740.0 683
LLPS-Leo-1320Lepisosteus oculatus88.740.0 681
LLPS-Xim-3446Xiphophorus maculatus88.740.0 684
LLPS-Orl-0987Oryzias latipes88.220.0 684
LLPS-Myl-3962Myotis lucifugus87.790.0 728
LLPS-Scf-4002Scleropages formosus87.70.0 674
LLPS-Icp-0161Ictalurus punctatus87.470.0 683
LLPS-Tar-3873Takifugu rubripes87.430.0 670
LLPS-Orn-2474Oreochromis niloticus87.170.0 673
LLPS-Dar-1146Danio rerio86.950.0 681
LLPS-Ten-3420Tetraodon nigroviridis86.420.0 658
LLPS-Gaa-1847Gasterosteus aculeatus86.20.0 659
LLPS-Asm-1282Astyanax mexicanus84.290.0 654
LLPS-Anp-1143Anas platyrhynchos68.240.0 527
LLPS-Lac-3779Latimeria chalumnae67.020.0 545
LLPS-Drm-1488Drosophila melanogaster64.939e-128 394
LLPS-Xet-1872Xenopus tropicalis63.612e-179 511
LLPS-Mod-3864Monodelphis domestica62.474e-170 488
LLPS-Tag-2730Taeniopygia guttata61.53e-173 497
LLPS-Cis-1356Ciona savignyi58.21e-152 443
LLPS-Cae-1882Caenorhabditis elegans56.354e-147 429
LLPS-Mea-3624Mesocricetus auratus55.484e-153 446
LLPS-Orm-0360Oryza meridionalis43.244e-88 285
LLPS-Orgl-1765Oryza glumaepatula43.248e-86 284
LLPS-Orp-2201Oryza punctata42.942e-82 282
LLPS-Orni-1735Oryza nivara42.733e-88 279
LLPS-Hea-0927Helianthus annuus42.731e-84 269
LLPS-Dac-0854Daucus carota42.65e-79 254
LLPS-Prp-1489Prunus persica42.432e-81 260
LLPS-Glm-2205Glycine max42.312e-77 250
LLPS-Mae-1364Manihot esculenta42.143e-82 263
LLPS-Sob-1366Sorghum bicolor41.911e-93 292
LLPS-Arl-1253Arabidopsis lyrata41.843e-87 276
LLPS-Abg-1756Absidia glauca41.763e-79 255
LLPS-Orbr-2255Oryza brachyantha41.643e-92 289
LLPS-Mua-0726Musa acuminata41.569e-59 198
LLPS-Phv-1275Phaseolus vulgaris41.542e-79 255
LLPS-Lep-1943Leersia perrieri41.495e-92 288
LLPS-Amt-2023Amborella trichopoda41.449e-91 285
LLPS-Ors-1247Oryza sativa41.384e-92 288
LLPS-Orr-2220Oryza rufipogon41.384e-92 288
LLPS-Org-0315Oryza glaberrima41.384e-92 288
LLPS-Ori-2473Oryza indica41.384e-92 288
LLPS-Sol-2499Solanum lycopersicum41.37e-87 275
LLPS-Met-0343Medicago truncatula40.871e-75 246
LLPS-Zem-0989Zea mays40.858e-91 285
LLPS-Sei-2269Setaria italica40.855e-92 288
LLPS-Cus-1779Cucumis sativus40.727e-79 254
LLPS-Viv-1568Vitis vinifera40.649e-85 269
LLPS-Vir-1545Vigna radiata40.641e-84 269
LLPS-Nia-1192Nicotiana attenuata40.556e-67 221
LLPS-Pot-0617Populus trichocarpa40.531e-77 251
LLPS-Php-0894Physcomitrella patens40.482e-87 276
LLPS-Via-2419Vigna angularis40.111e-83 266
LLPS-Scs-0660Sclerotinia sclerotiorum39.885e-73 238
LLPS-Art-0728Arabidopsis thaliana39.843e-87 275
LLPS-Thc-2002Theobroma cacao39.844e-82 262
LLPS-Sem-2358Selaginella moellendorffii39.825e-80 257
LLPS-Asc-1126Aspergillus clavatus39.816e-68 226
LLPS-Cog-0253Colletotrichum gloeosporioides39.679e-72 236
LLPS-Cogr-0796Colletotrichum graminicola39.671e-71 236
LLPS-Gor-1139Gossypium raimondii39.578e-80 256
LLPS-Asn-0323Aspergillus nidulans39.56e-74 241
LLPS-Hov-2079Hordeum vulgare39.371e-83 267
LLPS-Tra-2647Triticum aestivum39.372e-83 266
LLPS-Brd-1655Brachypodium distachyon39.372e-85 271
LLPS-Trv-0558Trichoderma virens39.346e-66 221
LLPS-Brr-0605Brassica rapa39.31e-87 276
LLPS-Coc-1435Corchorus capsularis39.32e-80 258
LLPS-Brn-0178Brassica napus39.31e-87 276
LLPS-Lem-0346Leptosphaeria maculans39.288e-71 233
LLPS-Tru-1028Triticum urartu39.123e-76 247
LLPS-Bro-2767Brassica oleracea39.13e-86 273
LLPS-Coo-0392Colletotrichum orbiculare39.033e-70 232
LLPS-Spr-1406Sporisorium reilianum38.91e-66 223
LLPS-Sac-1242Saccharomyces cerevisiae38.691e-67 225
LLPS-Chr-1121Chlamydomonas reinhardtii38.671e-69 230
LLPS-Tum-0366Tuber melanosporum38.481e-70 233
LLPS-Orb-0669Oryza barthii38.423e-86 274
LLPS-Nec-0193Neurospora crassa38.422e-74 243
LLPS-Gag-0887Gaeumannomyces graminis38.186e-74 242
LLPS-Aso-1029Aspergillus oryzae38.164e-67 224
LLPS-Asf-1174Aspergillus flavus38.164e-67 224
LLPS-Nef-1279Neosartorya fischeri38.026e-70 231
LLPS-Phn-0760Phaeosphaeria nodorum37.854e-68 226
LLPS-Asfu-0342Aspergillus fumigatus37.749e-70 231
LLPS-Usm-0959Ustilago maydis37.74e-74 242
LLPS-Ved-0472Verticillium dahliae37.682e-68 227
LLPS-Beb-1175Beauveria bassiana37.335e-68 226
LLPS-Osl-1083Ostreococcus lucimarinus37.176e-68 225
LLPS-Asni-1117Aspergillus niger36.982e-69 230
LLPS-Mao-1588Magnaporthe oryzae36.911e-72 238
LLPS-Pytr-1007Pyrenophora triticirepentis36.863e-73 240
LLPS-Pyt-1545Pyrenophora teres36.861e-73 241
LLPS-Map-0889Magnaporthe poae36.759e-71 233
LLPS-Yal-1345Yarrowia lipolytica36.311e-59 204
LLPS-Fuo-1043Fusarium oxysporum36.181e-68 228
LLPS-Fuv-0635Fusarium verticillioides36.182e-68 227
LLPS-Crn-1444Cryptococcus neoformans35.94e-59 203
LLPS-Dos-0885Dothistroma septosporum35.852e-68 227
LLPS-Blg-0439Blumeria graminis35.578e-66 221
LLPS-Fus-1454Fusarium solani35.048e-63 213
LLPS-Gas-0700Galdieria sulphuraria34.942e-54 190
LLPS-Mel-0158Melampsora laricipopulina34.593e-52 186
LLPS-Trr-0065Trichoderma reesei34.462e-67 225
LLPS-Chc-0321Chondrus crispus34.46e-73 238
LLPS-Zyt-1514Zymoseptoria tritici34.13e-67 224
LLPS-Ast-1320Aspergillus terreus34.094e-1886.7
LLPS-Put-1071Puccinia triticina33.72e-58 201
LLPS-Pug-1272Puccinia graminis33.241e-57 201
LLPS-Scj-0689Schizosaccharomyces japonicus33.073e-72 237
LLPS-Kop-1145Komagataella pastoris32.463e-63 213
LLPS-Asg-1126Ashbya gossypii31.952e-45 166
LLPS-Miv-1087Microbotryum violaceum31.721e-52 187
LLPS-Scc-1522Schizosaccharomyces cryophilus30.818e-70 231
LLPS-Cym-0112Cyanidioschyzon merolae30.04e-44 162
LLPS-Scp-0778Schizosaccharomyces pombe28.434e-63 213