• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Icp-1520
PLK2

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Serine/threonine-protein kinase PLK; Polo-like kinase
Gene Name: PLK2, LOC108277216
Ensembl Gene: ENSIPUG00000015264.1
Ensembl Protein: ENSIPUP00000022522.1
Organism: Ictalurus punctatus
Taxa ID: 7998
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Centrosome/Spindle pole bodyPredicted from orthologs(View)

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MDILRTIAHQ  PISNNKMCEH  THSKPTETRR  GKLEDSAHAT  QEMSRIISDC  TTGKCYCRGK  60
61    VLGKGGFAKC  YEFTDLGTGK  VYAVKIIPHT  RVSKPHQREK  IDREIELHRA  LHHKHIVQFY  120
121   YHFEDKDNIY  ILLEHCSRRS  LAHILKARKV  LTEPEVRYYL  RQIISGLKYL  HEQEILHRDL  180
181   KLGNFFINEA  MELKIGDFGL  AAKLEPVENR  RRTICGTPNY  LSPEVLNKQG  HGCESDVWAL  240
241   GCVMYTMLLG  RPPFETTNLK  ETYRCIREAR  YNMPSTLSPQ  AKHLISIMLA  KSPEDRPRLD  300
301   DILHHDFFSQ  GFTPDRLSVS  CCHTAPDLQH  TSPAKSFFKK  AAAALFGGKK  DKAKYFETLN  360
361   KLTKEEEDIH  RLRHDLRKAS  ISNQHCRQAL  EDSKPPVPSS  GKPVVAAKDG  GNKQQIRDTI  420
421   RMIVRGTLGS  CSSSSECLED  STMGTVADTV  ARVLRGCLEN  MPEANDISKE  SLNCSFQWVT  480
481   KWVDYSNKYG  FGYQLSDHTV  SVLFNNGTHM  SLLSDKKTVH  YYAELGQCTV  FSTSEAPEQF  540
541   VSQVTVLKYF  AHYMEENLMD  GGDLPNVIDI  SKPRLYLLQW  LKSDRALMML  FNDGTFQVNF  600
601   YHDHTKIILC  SQNEEYLLTY  INEDRVSTTL  RLSTLLCCGC  SSDLRSRMEY  ALNMLLQRCN  660
Nucleotide CDS Sequence (FASTA)
1     ATGGACATTC  TCAGGACTAT  CGCTCATCAA  CCTATAAGCA  ACAACAAAAT  GTGCGAACAC  60
61    ACACACAGCA  AACCGACTGA  GACGAGACGT  GGAAAGCTGG  AGGACAGCGC  GCACGCGACT  120
121   CAGGAAATGT  CGCGGATAAT  ATCTGACTGC  ACGACAGGGA  AATGCTACTG  TAGAGGAAAA  180
181   GTTCTCGGCA  AGGGTGGATT  TGCCAAATGT  TATGAATTTA  CAGATCTGGG  TACCGGCAAA  240
241   GTGTATGCTG  TGAAAATTAT  TCCACACACG  CGCGTCTCCA  AACCTCACCA  AAGGGAAAAG  300
301   ATTGACAGAG  AAATTGAACT  GCACAGAGCC  CTTCACCACA  AACACATTGT  CCAATTTTAC  360
361   TACCACTTTG  AGGACAAAGA  CAATATCTAC  ATCCTTCTAG  AGCACTGCAG  CAGACGATCA  420
421   TTGGCACATA  TTCTGAAAGC  TCGCAAGGTG  CTCACAGAAC  CCGAGGTTAG  GTACTACCTA  480
481   AGACAGATCA  TCTCAGGACT  GAAGTACCTC  CATGAACAGG  AAATCCTCCA  CAGAGACCTT  540
541   AAATTAGGTA  ACTTCTTCAT  TAATGAGGCA  ATGGAGCTGA  AGATAGGGGA  CTTTGGCCTG  600
601   GCAGCTAAGC  TAGAACCAGT  TGAAAACCGG  AGAAGAACAA  TATGCGGAAC  CCCAAACTAC  660
661   CTGTCTCCTG  AAGTCCTTAA  CAAGCAAGGC  CATGGCTGTG  AATCAGATGT  TTGGGCTCTT  720
721   GGCTGTGTAA  TGTACACGAT  GCTGTTGGGC  AGGCCACCAT  TTGAAACCAC  CAATCTGAAA  780
781   GAGACGTACC  GGTGCATAAG  GGAAGCGCGA  TACAACATGC  CTTCTACGCT  GTCTCCACAG  840
841   GCCAAGCACC  TCATTAGCAT  CATGCTTGCC  AAGAGCCCTG  AGGACAGGCC  AAGGCTGGAT  900
901   GACATCCTAC  ACCATGACTT  CTTCAGCCAG  GGTTTCACCC  CAGACAGACT  GTCTGTCAGC  960
961   TGCTGTCACA  CAGCTCCAGA  CCTCCAGCAC  ACCAGCCCTG  CCAAGAGCTT  CTTCAAGAAG  1020
1021  GCTGCAGCTG  CTCTGTTTGG  TGGCAAGAAG  GACAAAGCCA  AGTACTTTGA  AACCCTAAAT  1080
1081  AAACTGACAA  AAGAGGAAGA  GGATATCCAC  AGACTGCGAC  ATGACCTCAG  GAAGGCCTCA  1140
1141  ATCAGCAATC  AGCATTGCAG  GCAAGCTCTT  GAGGACAGTA  AGCCACCAGT  ACCATCTTCT  1200
1201  GGAAAGCCAG  TTGTTGCTGC  CAAGGATGGA  GGCAACAAGC  AGCAGATCCG  TGACACCATT  1260
1261  CGCATGATTG  TCCGAGGCAC  ACTGGGAAGC  TGCAGCAGCA  GCAGTGAATG  CTTGGAGGAT  1320
1321  AGTACGATGG  GTACTGTAGC  AGACACCGTT  GCCAGAGTAC  TCCGAGGCTG  TCTGGAGAAC  1380
1381  ATGCCAGAAG  CTAATGACAT  TTCAAAAGAG  AGCCTGAACT  GCAGCTTCCA  ATGGGTGACT  1440
1441  AAATGGGTGG  ACTATTCCAA  CAAGTATGGC  TTTGGTTACC  AGCTGTCTGA  TCACACAGTC  1500
1501  AGTGTCCTTT  TCAACAATGG  CACCCATATG  AGCTTGCTGT  CTGATAAGAA  GACAGTGCAT  1560
1561  TACTATGCAG  AGCTTGGTCA  GTGTACAGTC  TTCTCCACCA  GTGAGGCCCC  AGAGCAGTTT  1620
1621  GTCAGCCAGG  TCACAGTCCT  CAAGTATTTC  GCACATTATA  TGGAAGAAAA  TCTTATGGAT  1680
1681  GGTGGTGATT  TGCCCAATGT  GATTGATATC  AGCAAGCCAA  GGTTGTATCT  CCTGCAGTGG  1740
1741  CTCAAGTCAG  ATCGTGCACT  GATGATGCTC  TTCAATGATG  GCACCTTTCA  GGTAAACTTC  1800
1801  TACCATGACC  ACACCAAGAT  CATCTTGTGC  AGTCAGAATG  AGGAGTACTT  ACTGACATAC  1860
1861  ATCAATGAGG  ATCGTGTGTC  CACCACCCTA  CGCCTCAGCA  CACTACTCTG  CTGTGGATGC  1920
1921  TCCTCGGACC  TGCGGAGCCG  CATGGAGTAC  GCCCTCAACA  TGCTGCTCCA  GAGGTGCAAC  1980
1981  TGA  1983

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Asm-2044Astyanax mexicanus89.580.01078
LLPS-Dar-0457Danio rerio83.990.01040
LLPS-Leo-2768Lepisosteus oculatus82.580.01019
LLPS-Dio-1850Dipodomys ordii81.210.0 917
LLPS-Mod-0218Monodelphis domestica80.750.0 894
LLPS-Anp-1655Anas platyrhynchos78.960.0 899
LLPS-Tag-0825Taeniopygia guttata78.770.0 927
LLPS-Lac-3842Latimeria chalumnae78.650.0 998
LLPS-Fia-1202Ficedula albicollis78.40.0 874
LLPS-Meg-2442Meleagris gallopavo77.450.0 683
LLPS-Scm-1062Scophthalmus maximus77.20.0 751
LLPS-Gaa-2963Gasterosteus aculeatus75.910.0 919
LLPS-Orn-0627Oreochromis niloticus75.760.0 946
LLPS-Mum-3922Mus musculus75.730.0 960
LLPS-Fud-1266Fukomys damarensis75.580.0 955
LLPS-Mea-1992Mesocricetus auratus75.550.0 962
LLPS-Ran-1488Rattus norvegicus75.550.0 961
LLPS-Cap-0693Cavia porcellus75.550.0 955
LLPS-Aon-1064Aotus nancymaae75.510.0 963
LLPS-Caj-0565Callithrix jacchus75.360.0 957
LLPS-Gog-3616Gorilla gorilla75.070.0 957
LLPS-Hos-2483Homo sapiens75.070.0 957
LLPS-Pat-3809Pan troglodytes75.070.0 957
LLPS-Pap-2243Pan paniscus75.070.0 957
LLPS-Pes-1243Pelodiscus sinensis75.070.0 942
LLPS-Poa-1089Pongo abelii75.070.0 956
LLPS-Gaga-0196Gallus gallus75.00.0 950
LLPS-Caf-1701Canis familiaris74.960.0 954
LLPS-Chs-0321Chlorocebus sabaeus74.930.0 956
LLPS-Maf-3953Macaca fascicularis74.930.0 956
LLPS-Cea-1705Cercocebus atys74.930.0 956
LLPS-Bot-2100Bos taurus74.930.0 957
LLPS-Ova-2091Ovis aries74.930.0 956
LLPS-Paa-3216Papio anubis74.930.0 955
LLPS-Mal-0199Mandrillus leucophaeus74.930.0 956
LLPS-Man-4485Macaca nemestrina74.930.0 956
LLPS-Rhb-2924Rhinopithecus bieti74.930.0 956
LLPS-Mam-1613Macaca mulatta74.930.0 956
LLPS-Anc-3065Anolis carolinensis74.930.0 948
LLPS-Orc-1564Oryctolagus cuniculus74.890.0 956
LLPS-Tar-0777Takifugu rubripes74.850.0 929
LLPS-Xim-0654Xiphophorus maculatus74.850.0 927
LLPS-Ten-3591Tetraodon nigroviridis74.850.0 929
LLPS-Aim-1335Ailuropoda melanoleuca74.780.0 953
LLPS-Fec-0596Felis catus74.780.0 952
LLPS-Loa-1402Loxodonta africana74.780.0 959
LLPS-Otg-0020Otolemur garnettii74.780.0 957
LLPS-Eqc-0333Equus caballus74.780.0 953
LLPS-Nol-1875Nomascus leucogenys74.780.0 957
LLPS-Pof-2274Poecilia formosa74.70.0 926
LLPS-Sus-1551Sus scrofa74.640.0 954
LLPS-Ict-3224Ictidomys tridecemlineatus74.560.0 957
LLPS-Xet-2680Xenopus tropicalis74.550.0 935
LLPS-Scf-2038Scleropages formosus74.240.0 915
LLPS-Myl-0600Myotis lucifugus74.110.0 937
LLPS-Orl-1386Oryzias latipes69.770.0 831
LLPS-Ora-2084Ornithorhynchus anatinus57.398e-120 377
LLPS-Urm-0006Ursus maritimus53.965e-99 322
LLPS-Sah-3021Sarcophilus harrisii53.47e-67 233
LLPS-Tut-0801Tursiops truncatus53.217e-98 319
LLPS-Cii-0177Ciona intestinalis53.192e-66 231
LLPS-Cis-1412Ciona savignyi52.962e-106 341
LLPS-Mup-2314Mustela putorius furo52.50.0 607
LLPS-Cas-1457Carlito syrichta51.41e-98 322
LLPS-Cym-0181Cyanidioschyzon merolae50.364e-82 283
LLPS-Drm-0031Drosophila melanogaster48.579e-89 295
LLPS-Cae-0160Caenorhabditis elegans48.445e-88 295
LLPS-Gas-0734Galdieria sulphuraria46.262e-80 276
LLPS-Kop-0445Komagataella pastoris45.521e-74 259
LLPS-Crn-1212Cryptococcus neoformans45.178e-78 271
LLPS-Scp-0032Schizosaccharomyces pombe45.092e-75 261
LLPS-Scj-0236Schizosaccharomyces japonicus44.741e-70 249
LLPS-Nec-0057Neurospora crassa44.441e-63 232
LLPS-Usm-0705Ustilago maydis43.771e-69 249
LLPS-Spr-0015Sporisorium reilianum43.772e-69 248
LLPS-Miv-0734Microbotryum violaceum43.435e-67 239
LLPS-Coo-0403Colletotrichum orbiculare43.372e-62 228
LLPS-Mao-0041Magnaporthe oryzae43.379e-64 232
LLPS-Cogr-0721Colletotrichum graminicola43.371e-63 232
LLPS-Yal-0838Yarrowia lipolytica43.027e-68 241
LLPS-Gag-0470Gaeumannomyces graminis43.011e-63 233
LLPS-Map-0869Magnaporthe poae43.013e-63 231
LLPS-Asg-0043Ashbya gossypii42.913e-70 248
LLPS-Beb-0869Beauveria bassiana42.715e-66 239
LLPS-Cog-0395Colletotrichum gloeosporioides42.651e-61 226
LLPS-Scc-0087Schizosaccharomyces cryophilus42.612e-75 262
LLPS-Fuo-1153Fusarium oxysporum42.314e-63 231
LLPS-Tum-0411Tuber melanosporum42.182e-74 258
LLPS-Fus-0399Fusarium solani41.643e-62 228
LLPS-Trv-0672Trichoderma virens41.264e-62 228
LLPS-Asni-0244Aspergillus niger41.21e-66 242
LLPS-Trr-0765Trichoderma reesei40.564e-61 224
LLPS-Asc-1153Aspergillus clavatus40.539e-67 242
LLPS-Asfu-1303Aspergillus fumigatus40.531e-65 239
LLPS-Nef-0211Neosartorya fischeri40.21e-65 238
LLPS-Sac-0053Saccharomyces cerevisiae39.685e-69 244
LLPS-Asf-0412Aspergillus flavus39.533e-63 232
LLPS-Abg-1366Absidia glauca39.388e-62 222
LLPS-Osl-0110Ostreococcus lucimarinus39.37e-63 227
LLPS-Asn-0176Aspergillus nidulans39.21e-62 230
LLPS-Put-0102Puccinia triticina38.945e-66 239
LLPS-Blg-0520Blumeria graminis37.656e-62 227
LLPS-Pug-0706Puccinia graminis37.658e-64 233
LLPS-Mel-0993Melampsora laricipopulina36.392e-66 240