• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Icp-1189
limk1

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: LIM domain kinase 1 isoform X1
Gene Name: limk1
Ensembl Gene: ENSIPUG00000007559.1
Ensembl Protein: ENSIPUP00000011142.1
Organism: Ictalurus punctatus
Taxa ID: 7998
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Centrosome/Spindle pole bodyPredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MRLMLLCCTW  TDERMGEDEA  GGRLPLCAGC  RQHIYDEQYL  QALSTDWHTV  CFRCCECSVS  60
61    LSRWYYEKDG  RLFCRKDYWA  KFGELCHGCS  EPITTGLIMV  AGEQKYHPEC  FTCLNCRTFI  120
121   GDGDNYALVE  RSKLYCGHCY  YETIVTPATL  PDSPCSRIPH  TVTLVSIPAS  TDGKRGFSLS  180
181   IDQGSSPNGY  TTDYNHTVRV  SQVDSECISP  DVKNAIHVGD  RILEINGTPI  RNVPLDEIDL  240
241   LIQETSRLLQ  LTIEHDPLDS  DNPSSSFEDQ  VDGPSPLPER  HSPVPPITQP  PNHDINNLRS  300
301   RMITRSYSID  KSPCSSNSVS  PMSLRKDIGR  SESLRVVTNR  THRIFRPSDL  IHGEVLGKGC  360
361   YGQAIKVTHR  ETGEVMVMKE  LIRFDDETQR  TFLKEVKVMR  CLDHPNVLKF  IGVLYKDKRL  420
421   NFIAEYIKGG  TLRDIIKKMD  SNYPWNQRVS  FAKDIASGMA  YLHSMNIIHR  DLNSYNCLVR  480
481   ENNSVVVADF  GLARLMVEDK  NQDKLGKLQG  VKKPDRRKRY  TVVGNPYWMA  PEMIHGKSYD  540
541   EKVDIFSFGI  MLCEIIGRVN  ADPDYLPRAI  DFGLNVNGFL  EHYYPPDCPR  SFFPLAVLCC  600
601   DLDHEKRPAF  AKLEEWLEKL  KMHLNMRFLL  VSELEQIHLD  FWQKHPPVEN  QLPTHREQPE  660
Nucleotide CDS Sequence (FASTA)
1     ATGAACTTGC  TTCCTCAAAC  TCACACAAAG  GTCCTCGCTC  TCAGAGGAGA  GATGTCACGC  60
61    CGCGACCAAC  GCTGCAGAAG  TCACTCAAGT  GGCAGAAAAT  GCTGTGAATG  CAGTGTGTCT  120
121   CTGTCCCGCT  GGTACTATGA  GAAAGATGGA  CGTCTCTTCT  GTAGGAAGGA  CTACTGGGCT  180
181   AAGTTTGGGG  AGTTGTGTCA  TGGCTGCTCT  GAGCCTATCA  CCACTGGGCT  CATCATGGTT  240
241   GCAGGTGAGC  AGAAGTATCA  CCCGGAGTGT  TTCACCTGCC  TGAACTGCCG  CACCTTCATC  300
301   GGAGATGGAG  ACAACTACGC  TCTGGTGGAG  AGGTCCAAGC  TCTACTGTGG  ACATTGTTAT  360
361   TATGAGACCA  TCGTGACCCC  TGCGACCCTG  CCTGATTCTC  CATGCTCGCG  AATCCCTCAC  420
421   ACAGTCACGC  TGGTGTCTAT  TCCAGCCTCC  ACAGATGGAA  AGCGTGGCTT  CTCTCTTTCC  480
481   ATCGATCAGG  GAAGCAGCCC  AAACGGCTAC  ACTACTGACT  ACAATCACAC  AGTCCGCGTG  540
541   TCCCAGGTGG  ATTCTGAGTG  CATCAGTCCA  GATGTGAAGA  ATGCCATACA  TGTTGGTGAC  600
601   CGTATCCTGG  AGATTAATGG  CACCCCTATC  CGGAATGTTC  CACTTGATGA  GATTGATTTG  660
661   CTCATCCAAG  AGACCAGTCG  ACTCCTGCAG  CTCACCATTG  AGCATGACCC  CCTTGACTCT  720
721   GACAACCCCA  GCAGCTCGTT  TGAGGATCAA  GTGGACGGAC  CGAGCCCACT  TCCTGAGAGA  780
781   CACAGCCCGG  TTCCACCAAT  CACACAGCCA  CCGAATCACG  ACATCAACAA  CCTGCGCTCC  840
841   CGCATGATCA  CGCGTAGCTA  CAGTATTGAT  AAGTCACCAT  GCTCCAGTAA  TTCTGTGTCA  900
901   CCCATGTCTC  TGAGGAAGGA  CATTGGGCGC  TCCGAGTCTC  TTCGTGTCGT  AACAAACCGC  960
961   ACACACAGAA  TCTTCCGGCC  ATCTGATCTC  ATCCACGGAG  AAGTGCTCGG  AAAGGGCTGC  1020
1021  TACGGTCAGG  CTATTAAGGT  GACCCACAGG  GAGACGGGTG  AGGTGATGGT  CATGAAGGAG  1080
1081  CTCATTCGCT  TTGATGATGA  GACCCAGCGG  ACCTTCCTTA  AGGAGGTAAA  GGTAATGAGA  1140
1141  TGCCTGGACC  ACCCCAACGT  CCTCAAGTTC  ATCGGGGTCC  TCTACAAAGA  CAAGCGGCTG  1200
1201  AACTTCATTG  CCGAGTACAT  CAAAGGAGGC  ACCCTGAGGG  ACATCATTAA  GAAAATGGAC  1260
1261  AGTAATTATC  CCTGGAACCA  GAGAGTGAGT  TTTGCCAAGG  ATATTGCATC  TGGAATGGCC  1320
1321  TACCTACATT  CCATGAACAT  CATCCACCGT  GATCTCAACT  CTTACAACTG  TTTGGTCAGA  1380
1381  GAGAACAACA  GTGTTGTGGT  GGCAGACTTT  GGTCTTGCTC  GGCTAATGGT  AGAAGACAAG  1440
1441  AACCAGGACA  AACTGGGGAA  GCTCCAGGGT  GTGAAGAAAC  CAGACCGGAG  GAAGAGATAC  1500
1501  ACGGTTGTGG  GCAACCCTTA  CTGGATGGCT  CCAGAAATGA  TTCATGGAAA  GAGCTACGAT  1560
1561  GAGAAGGTGG  ACATCTTTTC  CTTCGGCATC  ATGCTGTGCG  AGATTATTGG  GCGAGTCAAT  1620
1621  GCAGATCCAG  ACTACTTGCC  ACGAGCCATA  GACTTTGGCC  TCAACGTGAA  CGGTTTCCTG  1680
1681  GAGCACTATT  ACCCTCCAGA  TTGCCCCCGC  TCTTTCTTCC  CCCTGGCTGT  CTTGTGCTGT  1740
1741  GACCTGGATC  ATGAGAAACG  GCCTGCTTTT  GCAAAGCTGG  AAGAATGGCT  TGAGAAGCTA  1800
1801  AAGATGCACT  TGAATATGCG  CTTCCTGCTG  GTCTCAGAAC  TGGAGCAGAT  CCATCTAGAC  1860
1861  TTCTGGCAGA  AGCATCCACC  TGTTGAGAAC  CAGCTGCCCA  CTCATCGAGA  GCAGCCCGAA  1920
1921  TAG  1923

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Asm-1770Astyanax mexicanus89.390.01212
LLPS-Scf-3464Scleropages formosus86.250.01172
LLPS-Leo-2782Lepisosteus oculatus83.380.01135
LLPS-Orn-1824Oreochromis niloticus82.220.01130
LLPS-Pof-3365Poecilia formosa80.650.01100
LLPS-Scm-2853Scophthalmus maximus80.390.01011
LLPS-Dar-3660Danio rerio80.360.01065
LLPS-Gaa-2720Gasterosteus aculeatus80.150.01092
LLPS-Xim-3956Xiphophorus maculatus80.060.01094
LLPS-Orl-0268Oryzias latipes77.270.01037
LLPS-Mod-0845Monodelphis domestica75.120.0 899
LLPS-Fia-0929Ficedula albicollis74.80.0 926
LLPS-Tut-1118Tursiops truncatus74.560.0 853
LLPS-Meg-2977Meleagris gallopavo74.40.0 729
LLPS-Gaga-1888Gallus gallus73.910.0 976
LLPS-Anc-2963Anolis carolinensis73.750.0 836
LLPS-Ten-0473Tetraodon nigroviridis72.910.0 818
LLPS-Tar-2732Takifugu rubripes72.640.0 803
LLPS-Fec-1377Felis catus72.440.0 957
LLPS-Bot-3888Bos taurus72.10.0 945
LLPS-Mum-4299Mus musculus72.10.0 954
LLPS-Eqc-0478Equus caballus72.10.0 959
LLPS-Ict-3814Ictidomys tridecemlineatus72.070.0 914
LLPS-Cas-0425Carlito syrichta72.050.0 923
LLPS-Sus-3740Sus scrofa71.950.0 948
LLPS-Otg-3321Otolemur garnettii71.950.0 949
LLPS-Paa-0773Papio anubis71.880.0 915
LLPS-Cap-4054Cavia porcellus71.790.0 946
LLPS-Caf-3693Canis familiaris71.790.0 953
LLPS-Myl-2831Myotis lucifugus71.780.0 924
LLPS-Maf-3786Macaca fascicularis71.720.0 915
LLPS-Mam-4520Macaca mulatta71.720.0 915
LLPS-Man-0882Macaca nemestrina71.720.0 915
LLPS-Fud-2737Fukomys damarensis71.690.0 857
LLPS-Ran-2333Rattus norvegicus71.640.0 948
LLPS-Tag-1398Taeniopygia guttata71.620.0 841
LLPS-Urm-1996Ursus maritimus71.620.0 850
LLPS-Gog-4757Gorilla gorilla71.540.0 920
LLPS-Hos-2645Homo sapiens71.540.0 920
LLPS-Pap-2790Pan paniscus71.540.0 919
LLPS-Pat-3120Pan troglodytes71.540.0 920
LLPS-Caj-3646Callithrix jacchus71.520.0 931
LLPS-Nol-4644Nomascus leucogenys71.526e-65 231
LLPS-Chs-2026Chlorocebus sabaeus71.490.0 942
LLPS-Rhb-0737Rhinopithecus bieti71.230.0 917
LLPS-Dio-0946Dipodomys ordii70.810.0 889
LLPS-Orc-4063Oryctolagus cuniculus70.320.0 912
LLPS-Poa-1712Pongo abelii69.830.0 657
LLPS-Aim-2461Ailuropoda melanoleuca69.810.0 882
LLPS-Mup-0770Mustela putorius furo67.710.0 857
LLPS-Ora-1294Ornithorhynchus anatinus67.650.0 810
LLPS-Cea-4835Cercocebus atys67.60.0 844
LLPS-Sah-3746Sarcophilus harrisii67.090.0 701
LLPS-Lac-3343Latimeria chalumnae67.040.0 802
LLPS-Loa-1047Loxodonta africana66.980.0 816
LLPS-Mal-3362Mandrillus leucophaeus65.470.0 812
LLPS-Aon-4076Aotus nancymaae65.090.0 808
LLPS-Pes-1215Pelodiscus sinensis62.990.0 645
LLPS-Xet-3805Xenopus tropicalis61.460.0 775
LLPS-Anp-1863Anas platyrhynchos56.210.0 617
LLPS-Ova-3064Ovis aries46.243e-41 162
LLPS-Drm-0992Drosophila melanogaster43.735e-167 518
LLPS-Cii-1568Ciona intestinalis41.822e-136 420
LLPS-Mea-2054Mesocricetus auratus40.915e-44 170
LLPS-Cis-1021Ciona savignyi40.323e-53 189
LLPS-Mua-2429Musa acuminata35.563e-30 127
LLPS-Tru-1875Triticum urartu35.026e-32 134
LLPS-Sol-1189Solanum lycopersicum33.211e-32 136
LLPS-Mae-2117Manihot esculenta33.215e-32 135
LLPS-Tra-2921Triticum aestivum33.02e-34 142
LLPS-Sot-1080Solanum tuberosum32.962e-32 136
LLPS-Zem-1732Zea mays32.877e-32 132
LLPS-Prp-0967Prunus persica32.758e-30 128
LLPS-Php-0748Physcomitrella patens32.625e-34 138
LLPS-Sob-2376Sorghum bicolor32.532e-31 130
LLPS-Thc-0086Theobroma cacao32.59e-31 131
LLPS-Glm-1884Glycine max32.52e-32 136
LLPS-Sei-2285Setaria italica32.176e-31 129
LLPS-Brd-1460Brachypodium distachyon31.821e-29 125
LLPS-Vir-0968Vigna radiata30.911e-29 127
LLPS-Art-2046Arabidopsis thaliana30.86e-30 128
LLPS-Met-1944Medicago truncatula30.633e-31 133
LLPS-Viv-2444Vitis vinifera30.482e-29 127
LLPS-Usm-1077Ustilago maydis29.352e-29 128