• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Dio-0946
Limk1

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: LIM domain kinase 1
Gene Name: Limk1
Ensembl Gene: ENSDORG00000000148.2
Ensembl Protein: ENSDORP00000000136.2
Organism: Dipodomys ordii
Taxa ID: 10020
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Centrosome/Spindle pole bodyPredicted from orthologs(View)

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MTLLPTGSEL  PICASCGQRI  YDGQYLQALN  SDWHSDCFRC  SECGAALSHQ  YYEKDGRLFC  60
61    KKDYWARYGE  SCHGCSEHIT  KGLVMVAGEL  KYHPECFICL  ACGAFIGDGD  TYTLVEHSKL  120
121   YCGHCYYQTV  VTPVIEHILP  DSPGSHLPHT  VTLVSIPASA  HGKRGLSVSI  DPPHGPPGCS  180
181   SEHSRTVRVQ  GVDPGCMSPD  VKNSIHVGDR  ILEINGTPIR  NVPLDEIDLL  IQETSRLLQL  240
241   TLEHDPHDTL  GHGPGSEPSP  LGSPLYTPNQ  EAGGSARQKP  VLRSCSIDTS  PGAGSLASPA  300
301   SQRKDLGRSE  SLRVVCRPHR  IFRPSDLIHG  EVLGKGCFGQ  AIKVTHRETG  EVMVMKELIR  360
361   FDEETQRTFL  KEVKVMRCLE  HPNVLKFIGV  LYKDKRLNFI  TEYIKGGTLR  SIIKSMDSQY  420
421   PWSQRVSFAK  DIAAGMAYLH  SMNIIHRDLN  SHNCLVRENK  NVVVADFGLA  RLMVDEKPQP  480
481   EDLRSLKKPD  RKKRYTVVGN  PYWMAPEMIN  GRSYDEKVDV  FSFGIVLCEI  IGRVNADPDY  540
541   LPRTMDFGLN  VRGFLDRYCP  PSCPPSFFPI  AVHCCDLDPE  KRPSFMKLQQ  WLESLRMHVA  600
601   GHLPLGPQLE  QLERGFWETY  RRGESGLPAH  PEVPD  635
Nucleotide CDS Sequence (FASTA)
1     ATGACTCTGC  TCCCCACAGG  AAGTGAGCTG  CCCATCTGTG  CAAGCTGCGG  CCAGAGGATT  60
61    TATGACGGCC  AGTACCTCCA  AGCCTTGAAC  TCCGACTGGC  ACTCAGACTG  CTTCAGGTGC  120
121   AGCGAGTGTG  GCGCTGCGCT  ATCACACCAG  TACTACGAAA  AGGATGGGCG  GCTCTTCTGC  180
181   AAGAAGGACT  ACTGGGCCCG  CTATGGCGAG  TCGTGCCACG  GCTGCTCAGA  GCACATCACC  240
241   AAGGGGCTGG  TCATGGTGGC  CGGGGAGCTC  AAGTACCACC  CTGAGTGCTT  CATCTGCCTC  300
301   GCCTGCGGGG  CTTTCATCGG  GGATGGGGAC  ACCTACACGC  TGGTGGAGCA  CTCCAAGCTG  360
361   TACTGTGGAC  ACTGCTACTA  TCAGACCGTG  GTGACCCCTG  TCATCGAGCA  CATCCTGCCC  420
421   GACTCCCCTG  GCTCCCACCT  GCCCCACACG  GTCACTCTGG  TATCCATCCC  CGCCTCTGCC  480
481   CATGGCAAAC  GAGGCCTGTC  CGTCTCCATC  GACCCCCCTC  ATGGACCTCC  AGGCTGCAGC  540
541   TCAGAGCATT  CCCGCACTGT  TCGTGTGCAG  GGCGTGGACC  CAGGCTGCAT  GAGCCCAGAC  600
601   GTGAAGAATT  CCATCCATGT  GGGAGACAGG  ATCCTGGAAA  TCAACGGCAC  ACCCATAAGG  660
661   AACGTGCCAC  TGGATGAGAT  TGACCTGCTG  ATCCAGGAAA  CCAGCCGCCT  GCTCCAGCTG  720
721   ACTCTGGAAC  ACGACCCTCA  TGACACACTG  GGCCATGGGC  CAGGGTCTGA  ACCCAGCCCC  780
781   CTGGGCTCCC  CATTGTACAC  CCCCAACCAG  GAAGCTGGAG  GTTCTGCCCG  GCAGAAACCT  840
841   GTGCTGAGAA  GCTGCAGCAT  CGACACATCC  CCGGGTGCGG  GCTCTCTGGC  TTCGCCGGCC  900
901   TCCCAGCGCA  AGGACCTGGG  TCGCTCAGAG  TCCCTCCGTG  TGGTCTGCCG  GCCGCACCGC  960
961   ATCTTCCGGC  CCTCCGACCT  CATCCATGGT  GAGGTGCTGG  GCAAGGGCTG  CTTCGGCCAG  1020
1021  GCCATCAAGG  TGACTCACCG  GGAGACAGGG  GAGGTGATGG  TGATGAAGGA  GCTGATCCGC  1080
1081  TTTGATGAGG  AGACGCAGAG  GACGTTCCTC  AAGGAGGTGA  AGGTCATGCG  GTGCCTGGAG  1140
1141  CACCCCAACG  TTCTCAAGTT  CATTGGGGTG  CTGTACAAGG  ACAAAAGGCT  GAACTTCATC  1200
1201  ACCGAGTATA  TCAAAGGGGG  CACCCTGCGG  AGCATCATCA  AGAGCATGGA  CAGCCAGTAT  1260
1261  CCGTGGAGCC  AGAGGGTGAG  CTTTGCCAAG  GACATCGCTG  CAGGAATGGC  CTACCTCCAC  1320
1321  TCCATGAACA  TTATCCACCG  GGACCTCAAC  TCGCACAACT  GCCTCGTTCG  AGAGAACAAG  1380
1381  AACGTGGTGG  TGGCCGACTT  CGGGCTGGCT  CGCCTCATGG  TCGATGAGAA  ACCACAGCCT  1440
1441  GAAGACCTGC  GCAGCCTCAA  GAAGCCAGAT  CGCAAAAAGC  GCTACACGGT  GGTGGGCAAC  1500
1501  CCATACTGGA  TGGCACCAGA  GATGATCAAT  GGCCGCAGCT  ATGATGAGAA  GGTGGACGTG  1560
1561  TTTTCCTTTG  GAATTGTCCT  GTGTGAGATC  ATCGGACGGG  TGAACGCAGA  CCCTGACTAC  1620
1621  CTGCCACGCA  CCATGGACTT  TGGCCTCAAC  GTGCGGGGCT  TTCTGGACCG  TTACTGTCCC  1680
1681  CCCAGCTGTC  CCCCCAGCTT  CTTCCCCATT  GCTGTGCACT  GCTGCGACCT  GGATCCTGAG  1740
1741  AAGAGGCCCT  CCTTCATGAA  GCTGCAGCAG  TGGCTGGAGT  CGCTCCGCAT  GCACGTGGCC  1800
1801  GGCCACCTGC  CACTGGGCCC  ACAGCTGGAG  CAGCTGGAGA  GGGGCTTCTG  GGAGACGTAC  1860
1861  CGGCGAGGCG  AGAGCGGCCT  GCCCGCCCAC  CCCGAGGTCC  CCGACTGA  1908

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Sus-3740Sus scrofa94.590.01158
LLPS-Bot-3888Bos taurus94.440.01151
LLPS-Ict-3814Ictidomys tridecemlineatus94.270.01147
LLPS-Tut-1118Tursiops truncatus94.190.01027
LLPS-Fec-1377Felis catus94.120.01146
LLPS-Pat-3120Pan troglodytes93.80.01154
LLPS-Hos-2645Homo sapiens93.80.01154
LLPS-Gog-4757Gorilla gorilla93.80.01154
LLPS-Pap-2790Pan paniscus93.640.01151
LLPS-Rhb-0737Rhinopithecus bieti93.480.01155
LLPS-Mam-4520Macaca mulatta93.470.01155
LLPS-Man-0882Macaca nemestrina93.470.01154
LLPS-Paa-0773Papio anubis93.470.01154
LLPS-Maf-3786Macaca fascicularis93.470.01155
LLPS-Eqc-0478Equus caballus93.320.01141
LLPS-Ran-2333Rattus norvegicus93.320.01146
LLPS-Chs-2026Chlorocebus sabaeus93.320.01152
LLPS-Myl-2831Myotis lucifugus93.210.01139
LLPS-Mum-4299Mus musculus93.160.01147
LLPS-Otg-3321Otolemur garnettii93.020.01139
LLPS-Cap-4054Cavia porcellus92.850.01139
LLPS-Cas-0425Carlito syrichta92.560.01152
LLPS-Orc-4063Oryctolagus cuniculus91.90.01119
LLPS-Fud-2737Fukomys damarensis91.290.01056
LLPS-Caf-3693Canis familiaris91.260.01111
LLPS-Caj-3646Callithrix jacchus91.10.01112
LLPS-Aim-2461Ailuropoda melanoleuca90.350.01095
LLPS-Poa-1712Pongo abelii90.040.0 784
LLPS-Nol-4644Nomascus leucogenys89.387e-92 303
LLPS-Cea-4835Cercocebus atys89.210.01082
LLPS-Mup-0770Mustela putorius furo88.380.01060
LLPS-Mod-0845Monodelphis domestica88.320.0 993
LLPS-Urm-1996Ursus maritimus87.420.01019
LLPS-Loa-1047Loxodonta africana86.830.01053
LLPS-Mal-3362Mandrillus leucophaeus86.460.01044
LLPS-Aon-4076Aotus nancymaae83.310.0 974
LLPS-Fia-0929Ficedula albicollis82.680.0 966
LLPS-Gaga-1888Gallus gallus81.570.01010
LLPS-Meg-2977Meleagris gallopavo80.280.0 779
LLPS-Anc-2963Anolis carolinensis79.610.0 865
LLPS-Sah-3746Sarcophilus harrisii78.970.0 817
LLPS-Tag-1398Taeniopygia guttata78.680.0 875
LLPS-Ora-1294Ornithorhynchus anatinus76.020.0 923
LLPS-Leo-2782Lepisosteus oculatus74.920.0 922
LLPS-Scf-3464Scleropages formosus72.920.0 913
LLPS-Dar-3660Danio rerio72.060.0 875
LLPS-Asm-1770Astyanax mexicanus72.030.0 900
LLPS-Pes-1215Pelodiscus sinensis71.570.0 698
LLPS-Orn-1824Oreochromis niloticus71.170.0 884
LLPS-Pof-3365Poecilia formosa71.080.0 887
LLPS-Xim-3956Xiphophorus maculatus70.470.0 884
LLPS-Icp-1189Ictalurus punctatus70.230.0 876
LLPS-Gaa-2720Gasterosteus aculeatus69.770.0 862
LLPS-Scm-2853Scophthalmus maximus69.60.0 830
LLPS-Xet-3805Xenopus tropicalis69.40.0 816
LLPS-Lac-3343Latimeria chalumnae69.10.0 776
LLPS-Orl-0268Oryzias latipes68.340.0 832
LLPS-Tar-2732Takifugu rubripes65.710.0 669
LLPS-Ten-0473Tetraodon nigroviridis65.220.0 681
LLPS-Anp-1863Anas platyrhynchos64.660.0 700
LLPS-Drm-0992Drosophila melanogaster53.871e-100 339
LLPS-Ova-3064Ovis aries48.338e-45 172
LLPS-Mea-2054Mesocricetus auratus43.043e-45 173
LLPS-Cii-1568Ciona intestinalis40.983e-130 403
LLPS-Cis-1021Ciona savignyi39.751e-50 181
LLPS-Tru-1875Triticum urartu35.642e-29 127
LLPS-Php-0748Physcomitrella patens35.643e-33 136
LLPS-Glm-1884Glycine max35.17e-30 128
LLPS-Sei-2008Setaria italica34.47e-29 127
LLPS-Zem-1095Zea mays34.042e-29 128
LLPS-Orm-2053Oryza meridionalis33.683e-28 124
LLPS-Lep-0717Leersia perrieri33.211e-28 124
LLPS-Brd-2351Brachypodium distachyon32.988e-28 123
LLPS-Viv-1039Vitis vinifera32.971e-28 125
LLPS-Org-1266Oryza glaberrima32.859e-28 121
LLPS-Orr-2001Oryza rufipogon32.859e-28 121
LLPS-Ors-0939Oryza sativa32.859e-28 121
LLPS-Ori-0065Oryza indica32.855e-28 122
LLPS-Mae-2117Manihot esculenta31.973e-28 123
LLPS-Sob-2344Sorghum bicolor31.882e-29 126
LLPS-Thc-0086Theobroma cacao31.791e-29 128
LLPS-Mua-2326Musa acuminata31.755e-28 122
LLPS-Tra-2921Triticum aestivum31.636e-31 132
LLPS-Prp-0967Prunus persica31.584e-30 129
LLPS-Sol-1189Solanum lycopersicum31.442e-31 133
LLPS-Sot-1080Solanum tuberosum31.46e-32 134
LLPS-Arl-2623Arabidopsis lyrata31.236e-28 124
LLPS-Gas-1313Galdieria sulphuraria31.011e-30 132
LLPS-Orbr-1889Oryza brachyantha30.671e-27 122
LLPS-Usm-1077Ustilago maydis30.636e-29 126
LLPS-Met-1944Medicago truncatula29.339e-30 128
LLPS-Phv-2181Phaseolus vulgaris29.282e-28 124
LLPS-Vir-0968Vigna radiata28.971e-27 122