• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Icp-0746
vcp

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Transitional Endoplasmic reticulum ATPase
Gene Name: vcp
Ensembl Gene: ENSIPUG00000007814.1
Ensembl Protein: ENSIPUP00000011536.1
Organism: Ictalurus punctatus
Taxa ID: 7998
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Stress granule, Postsynaptic densityPredicted from orthologs(View)

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MASGGESKND  DLSTAILKQK  NRPNRLIVDE  SINEDNSVVS  LSQAKMDELQ  LFRGDTVLLK  60
61    GKKRRETVCI  VLSDDSCSDE  KVRMNRVVRN  NLRVRLGDVI  SIQPCPDVKY  GKRIHVLPID  120
121   DTVEGITGNL  FEVYLKPYFL  EAYRPIRKGD  IFLVRGGMRA  VEFKVVETDP  SPYCIVAPDT  180
181   VIHCEGEPIK  REDEEESLNE  VGYDDIGGVR  KQLAQIKEMV  ELPLRHPALF  KAIGVKPPRG  240
241   ILLYGPPGTG  KTLIARAVAN  ETGAFFFLIN  GPEIMSKLAG  ESESNLRKAF  EEAEKNAPAI  300
301   IFIDELDAIA  PKREKTHGEV  ERRIVSQLLT  LMDGLKQRAH  VIVMAATNRP  NSIDPALRRF  360
361   GRFDREVDIG  IPDATGRLEI  LQIHTKNMKL  ADDVDLEQVA  NETHGHVGAD  LAALCSEAAL  420
421   QAIRKKMDLI  DLEDETIDAE  VMNSLAVTMD  DFRWALSQSN  PSALRETVVE  VPNISWEDIG  480
481   GLDDVKRELQ  ELVQYPVEHP  DKFLKFGMTP  SKGVLFYGPP  GCGKTLLAKA  IANECQANFI  540
541   SIKGPELLTM  WFGESEANVR  EIFDKARQAA  PCVLFFDELD  SIAKARGGSA  GDGGGAADRV  600
601   INQILTEMDG  MSSKKNVFII  GATNRPDIID  PAILRPGRLD  QLIYIPLPDE  KSRMAILKAN  660
661   LRKSPIAKDV  DLDFLAKMTN  GFSGADLTEV  CQRACKLAIR  ESIENEIRRE  RERQTNPSAM  720
721   EVEEDDPVPE  IRKDHFEEAM  RFARRSVSDN  DIRKYEMFAQ  TLQQSRGFGS  FRFPSSNQGG  780
781   GGPSQGSAGG  TGGNVFNEDN  DDDLYG  806
Nucleotide CDS Sequence (FASTA)
1     ATGGCTTCGG  GTGGAGAATC  TAAAAATGAT  GATCTTTCTA  CTGCCATTTT  AAAACAAAAG  60
61    AACAGACCCA  ACAGGTTGAT  CGTTGATGAA  TCCATCAATG  AAGATAACAG  TGTGGTCTCG  120
121   CTCTCTCAGG  CCAAGATGGA  TGAGCTTCAG  CTTTTCAGGG  GGGACACTGT  GCTGCTGAAG  180
181   GGCAAGAAAA  GGAGGGAGAC  GGTTTGCATC  GTACTGTCTG  ACGATAGCTG  CTCTGATGAG  240
241   AAAGTGCGCA  TGAACAGGGT  GGTGCGCAAT  AACCTCAGGG  TTCGTCTCGG  AGATGTCATC  300
301   AGCATTCAGC  CATGCCCAGA  TGTGAAGTAT  GGGAAACGCA  TCCATGTTCT  GCCCATTGAT  360
361   GACACAGTGG  AGGGAATCAC  TGGCAACTTA  TTTGAGGTGT  ACCTGAAGCC  TTACTTCCTA  420
421   GAGGCTTACC  GGCCAATCCG  TAAAGGTGAT  ATCTTCCTTG  TAAGAGGAGG  CATGCGTGCT  480
481   GTTGAGTTCA  AAGTGGTGGA  GACTGATCCT  AGCCCTTACT  GTATAGTGGC  TCCAGACACT  540
541   GTCATTCACT  GTGAAGGAGA  ACCTATTAAG  CGTGAGGACG  AAGAAGAATC  TCTGAATGAA  600
601   GTCGGCTACG  ATGACATTGG  AGGTGTGAGG  AAGCAGCTGG  CTCAGATCAA  AGAAATGGTG  660
661   GAGCTGCCGC  TCAGGCACCC  AGCACTCTTC  AAGGCCATTG  GCGTGAAACC  TCCCCGTGGT  720
721   ATTCTTCTGT  ACGGACCCCC  CGGAACTGGA  AAAACTCTGA  TTGCTCGCGC  TGTCGCAAAT  780
781   GAAACTGGAG  CATTCTTCTT  CCTGATCAAC  GGCCCTGAAA  TTATGAGTAA  ACTGGCTGGT  840
841   GAGTCTGAGA  GCAACCTGCG  TAAAGCTTTT  GAAGAAGCCG  AGAAAAACGC  TCCTGCCATC  900
901   ATCTTCATTG  ATGAACTGGA  TGCTATTGCA  CCTAAGAGAG  AGAAGACTCA  CGGTGAGGTA  960
961   GAGAGGCGCA  TTGTGTCTCA  GCTGCTCACC  CTGATGGACG  GACTGAAGCA  GCGGGCTCAC  1020
1021  GTGATCGTCA  TGGCTGCCAC  CAACAGACCC  AACAGCATTG  ACCCAGCTCT  CAGGCGATTC  1080
1081  GGCCGCTTTG  ACAGAGAGGT  GGACATTGGT  ATTCCTGATG  CCACAGGAAG  ACTGGAAATC  1140
1141  CTGCAGATCC  ACACTAAGAA  CATGAAGCTG  GCTGATGATG  TTGATCTGGA  ACAGGTTGCC  1200
1201  AACGAGACCC  ATGGTCATGT  GGGTGCTGAT  TTGGCTGCCC  TGTGCTCAGA  GGCTGCTCTG  1260
1261  CAGGCCATCC  GCAAGAAGAT  GGACCTCATT  GACCTGGAGG  ATGAGACGAT  TGACGCAGAG  1320
1321  GTCATGAACT  CCCTGGCTGT  CACTATGGAT  GACTTCAGGT  GGGCCCTGAG  CCAGAGCAAC  1380
1381  CCATCGGCTC  TGCGCGAGAC  TGTTGTGGAA  GTGCCCAACA  TCAGCTGGGA  GGACATTGGT  1440
1441  GGACTGGATG  ATGTCAAGAG  AGAACTGCAG  GAACTGGTGC  AGTACCCAGT  GGAGCATCCA  1500
1501  GACAAATTCC  TGAAGTTTGG  TATGACTCCA  TCCAAGGGTG  TGTTGTTCTA  TGGTCCGCCA  1560
1561  GGTTGTGGTA  AAACCCTCTT  GGCCAAGGCC  ATTGCCAATG  AGTGCCAGGC  CAACTTCATT  1620
1621  TCCATCAAAG  GCCCTGAACT  GCTAACCATG  TGGTTTGGAG  AGTCTGAGGC  TAATGTTCGT  1680
1681  GAGATCTTTG  ATAAGGCTCG  TCAAGCTGCC  CCATGCGTGC  TCTTCTTTGA  TGAGCTGGAC  1740
1741  TCCATTGCTA  AAGCCCGTGG  TGGAAGCGCA  GGTGACGGCG  GTGGAGCAGC  CGACCGCGTC  1800
1801  ATAAACCAGA  TCCTGACTGA  GATGGACGGC  ATGTCCAGCA  AGAAGAACGT  CTTCATCATT  1860
1861  GGCGCCACCA  ACAGACCGGA  TATAATTGAC  CCTGCCATCC  TCAGGCCTGG  CCGTCTGGAC  1920
1921  CAGCTTATCT  ACATCCCTCT  GCCCGATGAG  AAATCTCGCA  TGGCCATTCT  TAAAGCTAAC  1980
1981  CTCAGGAAGT  CTCCAATCGC  CAAGGATGTA  GACCTGGACT  TCCTGGCCAA  GATGACCAAT  2040
2041  GGCTTCTCTG  GTGCTGACTT  GACAGAGGTT  TGCCAGCGAG  CCTGCAAACT  GGCTATTCGT  2100
2101  GAGTCCATCG  AGAACGAGAT  CAGGAGGGAA  CGTGAGAGGC  AGACGAACCC  ATCAGCCATG  2160
2161  GAAGTGGAGG  AGGATGACCC  AGTGCCCGAG  ATCAGGAAGG  ACCACTTCGA  GGAGGCCATG  2220
2221  CGTTTCGCCC  GTCGCTCTGT  CAGTGACAAC  GACATCCGCA  AATACGAGAT  GTTTGCACAG  2280
2281  ACCCTGCAGC  AAAGCAGAGG  CTTTGGCAGT  TTCAGATTCC  CTTCCAGTAA  TCAGGGAGGA  2340
2341  GGTGGACCAA  GCCAAGGTTC  CGCAGGTGGC  ACTGGAGGGA  ATGTCTTCAA  TGAGGACAAC  2400
2401  GACGATGACC  TTTACGGATA  A  2421

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Dar-0124Danio rerio98.760.01461
LLPS-Leo-0922Lepisosteus oculatus98.640.01459
LLPS-Scf-1484Scleropages formosus98.380.01450
LLPS-Scm-0718Scophthalmus maximus97.520.01454
LLPS-Xim-0465Xiphophorus maculatus97.020.01450
LLPS-Sah-0814Sarcophilus harrisii97.00.01431
LLPS-Sus-2026Sus scrofa96.990.01427
LLPS-Gaa-1179Gasterosteus aculeatus96.90.01452
LLPS-Pof-0776Poecilia formosa96.90.01450
LLPS-Fia-0305Ficedula albicollis96.880.01431
LLPS-Orn-0745Oreochromis niloticus96.880.01443
LLPS-Urm-1807Ursus maritimus96.850.01358
LLPS-Fud-2089Fukomys damarensis96.750.01428
LLPS-Orl-2769Oryzias latipes96.750.01436
LLPS-Loa-1132Loxodonta africana96.750.01429
LLPS-Gaga-1611Gallus gallus96.750.01430
LLPS-Ran-0792Rattus norvegicus96.650.01436
LLPS-Mod-0606Monodelphis domestica96.650.01438
LLPS-Mea-0209Mesocricetus auratus96.630.01426
LLPS-Gog-1311Gorilla gorilla96.530.01436
LLPS-Caj-0929Callithrix jacchus96.530.01436
LLPS-Maf-3408Macaca fascicularis96.530.01436
LLPS-Mum-0997Mus musculus96.530.01436
LLPS-Chs-0638Chlorocebus sabaeus96.530.01436
LLPS-Cea-2649Cercocebus atys96.530.01436
LLPS-Mal-0762Mandrillus leucophaeus96.530.01436
LLPS-Dio-0057Dipodomys ordii96.530.01436
LLPS-Orc-0712Oryctolagus cuniculus96.530.01436
LLPS-Rhb-1139Rhinopithecus bieti96.530.01436
LLPS-Hos-1698Homo sapiens96.530.01436
LLPS-Pat-0632Pan troglodytes96.530.01436
LLPS-Pap-1534Pan paniscus96.530.01436
LLPS-Cas-1422Carlito syrichta96.530.01436
LLPS-Poa-0368Pongo abelii96.530.01436
LLPS-Cap-0590Cavia porcellus96.530.01436
LLPS-Mam-2019Macaca mulatta96.530.01436
LLPS-Mup-1577Mustela putorius furo96.40.01436
LLPS-Myl-0276Myotis lucifugus96.40.01437
LLPS-Bot-2920Bos taurus96.40.01436
LLPS-Fec-3017Felis catus96.40.01436
LLPS-Caf-1852Canis familiaris96.40.01436
LLPS-Paa-0740Papio anubis96.290.01431
LLPS-Otg-0202Otolemur garnettii96.280.01427
LLPS-Anp-2307Anas platyrhynchos96.280.01428
LLPS-Aim-1479Ailuropoda melanoleuca96.270.01429
LLPS-Aon-0373Aotus nancymaae96.150.01424
LLPS-Ict-0904Ictidomys tridecemlineatus96.150.01429
LLPS-Tut-0689Tursiops truncatus96.120.01410
LLPS-Xet-0910Xenopus tropicalis96.080.01354
LLPS-Eqc-1552Equus caballus96.020.01418
LLPS-Nol-1013Nomascus leucogenys95.920.01422
LLPS-Ora-0296Ornithorhynchus anatinus95.640.01414
LLPS-Pes-0788Pelodiscus sinensis95.510.01371
LLPS-Tar-1879Takifugu rubripes95.160.0 820
LLPS-Anc-1680Anolis carolinensis95.040.01432
LLPS-Ten-1386Tetraodon nigroviridis94.540.01443
LLPS-Tag-0701Taeniopygia guttata93.630.01361
LLPS-Ova-1264Ovis aries93.580.01423
LLPS-Meg-1745Meleagris gallopavo92.370.01202
LLPS-Lac-3801Latimeria chalumnae90.910.01103
LLPS-Cis-0849Ciona savignyi86.590.01281
LLPS-Cii-0589Ciona intestinalis85.440.01262
LLPS-Drm-0157Drosophila melanogaster84.430.01256
LLPS-Asm-1636Astyanax mexicanus84.280.01160
LLPS-Man-2697Macaca nemestrina81.690.01144
LLPS-Cae-0195Caenorhabditis elegans81.00.01192
LLPS-Brn-1595Brassica napus80.50.01184
LLPS-Brr-1721Brassica rapa80.50.01181
LLPS-Bro-2750Brassica oleracea80.50.01184
LLPS-Hov-0321Hordeum vulgare80.370.01187
LLPS-Brd-1637Brachypodium distachyon80.370.01187
LLPS-Viv-0788Vitis vinifera80.370.01216
LLPS-Orp-0738Oryza punctata80.370.01214
LLPS-Sob-1049Sorghum bicolor80.260.01212
LLPS-Tra-1500Triticum aestivum80.240.01200
LLPS-Amt-0721Amborella trichopoda80.240.01210
LLPS-Tru-1253Triticum urartu80.240.01189
LLPS-Abg-1039Absidia glauca80.180.01203
LLPS-Zem-1199Zea mays80.130.01211
LLPS-Cus-1351Cucumis sativus80.110.01211
LLPS-Pot-0063Populus trichocarpa79.970.01216
LLPS-Orbr-0008Oryza brachyantha79.90.01214
LLPS-Art-0402Arabidopsis thaliana79.870.01199
LLPS-Vir-0466Vigna radiata79.840.01208
LLPS-Arl-0850Arabidopsis lyrata79.740.01200
LLPS-Lep-1460Leersia perrieri79.740.01193
LLPS-Php-0299Physcomitrella patens79.710.01185
LLPS-Sem-2355Selaginella moellendorffii79.710.01193
LLPS-Via-1117Vigna angularis79.710.01204
LLPS-Orm-0487Oryza meridionalis79.610.01214
LLPS-Chr-0100Chlamydomonas reinhardtii79.550.01189
LLPS-Sei-0858Setaria italica79.530.01203
LLPS-Orb-0399Oryza barthii79.510.01213
LLPS-Ori-0118Oryza indica79.510.01213
LLPS-Orgl-0154Oryza glumaepatula79.510.01213
LLPS-Ors-0321Oryza sativa79.510.01213
LLPS-Orr-1312Oryza rufipogon79.510.01213
LLPS-Sot-1499Solanum tuberosum79.480.01209
LLPS-Osl-0532Ostreococcus lucimarinus79.470.01190
LLPS-Phv-0688Phaseolus vulgaris79.450.01201
LLPS-Orni-0423Oryza nivara79.380.01213
LLPS-Org-0362Oryza glaberrima79.380.01209
LLPS-Met-0156Medicago truncatula79.320.01200
LLPS-Glm-0115Glycine max79.310.01212
LLPS-Hea-1671Helianthus annuus79.290.01203
LLPS-Gor-2281Gossypium raimondii79.290.01202
LLPS-Thc-0163Theobroma cacao79.030.01199
LLPS-Dac-0804Daucus carota78.940.01194
LLPS-Mae-0646Manihot esculenta78.90.01202
LLPS-Nia-0662Nicotiana attenuata78.90.01200
LLPS-Mua-2473Musa acuminata78.850.01187
LLPS-Prp-1161Prunus persica78.770.01199
LLPS-Sol-2351Solanum lycopersicum78.640.01181
LLPS-Gas-0515Galdieria sulphuraria77.690.01181
LLPS-Spr-1211Sporisorium reilianum77.360.01162
LLPS-Chc-0426Chondrus crispus77.220.01149
LLPS-Phn-0853Phaeosphaeria nodorum76.360.01071
LLPS-Mel-0495Melampsora laricipopulina76.170.01154
LLPS-Usm-0109Ustilago maydis75.480.01150
LLPS-Crn-0411Cryptococcus neoformans75.420.01140
LLPS-Cym-0087Cyanidioschyzon merolae75.390.01139
LLPS-Miv-0242Microbotryum violaceum75.030.01150
LLPS-Put-0137Puccinia triticina74.350.01154
LLPS-Pytr-1461Pyrenophora triticirepentis74.210.01121
LLPS-Coo-0032Colletotrichum orbiculare74.150.01120
LLPS-Pyt-1181Pyrenophora teres74.120.01120
LLPS-Lem-0655Leptosphaeria maculans74.080.01120
LLPS-Cog-0557Colletotrichum gloeosporioides74.080.01118
LLPS-Nec-0633Neurospora crassa74.050.01117
LLPS-Fus-0060Fusarium solani74.020.01129
LLPS-Map-1380Magnaporthe poae73.990.01120
LLPS-Pug-0193Puccinia graminis73.980.01153
LLPS-Cogr-0617Colletotrichum graminicola73.730.01119
LLPS-Fuv-1200Fusarium verticillioides73.630.01127
LLPS-Trr-0973Trichoderma reesei73.630.01124
LLPS-Fuo-0125Fusarium oxysporum73.630.01127
LLPS-Ast-0837Aspergillus terreus73.540.01119
LLPS-Asni-0139Aspergillus niger73.510.01106
LLPS-Gag-0137Gaeumannomyces graminis73.50.01122
LLPS-Nef-0641Neosartorya fischeri73.470.01119
LLPS-Asfu-0409Aspergillus fumigatus73.470.01118
LLPS-Tum-0621Tuber melanosporum73.380.01110
LLPS-Trv-0405Trichoderma virens73.370.01110
LLPS-Asc-0054Aspergillus clavatus73.310.01117
LLPS-Mao-0820Magnaporthe oryzae73.240.01118
LLPS-Scs-0443Sclerotinia sclerotiorum73.180.01119
LLPS-Asf-0755Aspergillus flavus73.150.01103
LLPS-Aso-0754Aspergillus oryzae73.150.01103
LLPS-Scp-0603Schizosaccharomyces pombe72.940.01088
LLPS-Ved-0929Verticillium dahliae72.940.01111
LLPS-Asn-0996Aspergillus nidulans72.820.01113
LLPS-Blg-1375Blumeria graminis72.750.01106
LLPS-Dos-0041Dothistroma septosporum72.270.01102
LLPS-Zyt-0327Zymoseptoria tritici71.980.01100
LLPS-Yal-0766Yarrowia lipolytica71.820.01098
LLPS-Scj-1330Schizosaccharomyces japonicus71.370.01090
LLPS-Asg-0841Ashbya gossypii71.280.01085
LLPS-Scc-0770Schizosaccharomyces cryophilus71.110.01088
LLPS-Kop-0019Komagataella pastoris70.710.01080
LLPS-Sac-0118Saccharomyces cerevisiae70.450.01083