• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Gas-0285
Gasu_53280

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: NAD-dependent histone deacetylase SIR2
Gene Name: Gasu_53280
Ensembl Gene: Gasu_53280
Ensembl Protein: EME27108
Organism: Galdieria sulphuraria
Taxa ID: 130081
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Stress granule, OthersPredicted from orthologs(View)

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblEME27108EME27108
UniProtM2XTW5, M2XTW5_GALSU
GeneBankKB454537EME27108.1
RefSeqXM_005703571.1XP_005703628.1

▼ SEQUENCE

Protein Sequence (FASTA)
1     MMSSPKRLCQ  RFKQDNLQQD  KTEEELAYDS  NWLDCDKAES  FQSNCPLASN  NQAPRMEQEE  60
61    DKSDTLEDTG  DQSGEQIDDY  ENTDKSESES  SSVEMAIEAF  IEEHSNSLEN  LRESLMDIGI  120
121   LVSLEQLEQL  QSEDIAALIR  NSIYKEPLLT  YRTKSEDLKN  IQDLARIIKQ  ASHILVVSGA  180
181   GISVSCGIPD  FRSAGGIYER  IQKTFSLFDP  QEIFDLNVFK  ESPELFYSFA  KEIIPRESTE  240
241   PSLSHRFIRD  LECHQKLLRN  YAQNIDGLES  IAGIDRVVYC  HGSFSAAHCL  RCNAHYSLDD  300
301   IRPDIVTGRV  PYCSFCGNRV  NWDTNIHESS  NNPSSEYKSC  IDNNSSTDGE  DEDRITPNII  360
361   KPDIVFFGEA  LSDQFFDCFE  SDRETADLLL  VIGTSLQVAP  VSKIPFCISA  EIPQVLINLE  420
421   PVGPSDWFDL  ELIGPCDVII  ERLYQLLGWQ  HGMNHVGCFK  EEQVQPRRFA  FQRDIK  476
Nucleotide CDS Sequence (FASTA)
1     ATGATGTCGA  GTCCAAAACG  ATTGTGTCAG  CGTTTCAAAC  AAGATAATCT  ACAACAAGAT  60
61    AAAACGGAAG  AGGAGTTAGC  TTATGATAGT  AACTGGTTAG  ACTGCGATAA  AGCGGAAAGC  120
121   TTTCAATCAA  ACTGTCCGTT  GGCTTCGAAC  AACCAGGCTC  CAAGAATGGA  ACAAGAAGAG  180
181   GACAAGAGTG  ATACTTTAGA  AGACACAGGT  GACCAAAGTG  GAGAGCAAAT  TGATGATTAT  240
241   GAAAATACTG  ATAAGAGTGA  AAGTGAGAGT  AGCAGTGTGG  AGATGGCTAT  TGAAGCTTTT  300
301   ATAGAAGAAC  ACAGCAACAG  TCTGGAGAAC  TTGAGAGAAT  CGTTGATGGA  CATAGGTATA  360
361   TTGGTGAGTC  TCGAACAACT  AGAACAGTTG  CAAAGCGAAG  ATATTGCAGC  TTTGATAAGA  420
421   AATTCTATAT  ATAAAGAACC  GCTGCTTACG  TACCGAACTA  AAAGCGAAGA  TTTGAAAAAT  480
481   ATTCAAGATT  TGGCTAGGAT  AATTAAACAG  GCTAGCCATA  TTTTGGTTGT  TAGTGGTGCA  540
541   GGTATTAGCG  TTAGTTGCGG  AATTCCTGAT  TTTCGTTCAG  CAGGTGGCAT  TTATGAACGC  600
601   ATTCAAAAGA  CATTTTCGTT  ATTCGATCCT  CAAGAGATAT  TCGACTTGAA  CGTATTCAAA  660
661   GAGAGTCCGG  AATTGTTTTA  TTCTTTTGCA  AAAGAGATCA  TTCCAAGAGA  GTCTACTGAA  720
721   CCTTCCTTGT  CTCATCGTTT  TATTCGAGAC  CTCGAATGTC  ATCAAAAGTT  GTTACGTAAT  780
781   TATGCACAAA  ATATTGATGG  CTTAGAAAGC  ATTGCAGGAA  TTGATCGGGT  TGTATATTGT  840
841   CACGGCTCAT  TTTCCGCTGC  ACATTGTTTG  CGTTGTAATG  CACATTATTC  TTTGGATGAT  900
901   ATTCGACCTG  ATATTGTAAC  AGGAAGAGTT  CCTTATTGTT  CTTTTTGCGG  AAATCGAGTG  960
961   AACTGGGACA  CAAATATCCA  TGAATCATCT  AACAATCCTT  CTTCAGAGTA  CAAGTCATGT  1020
1021  ATAGATAATA  ACAGCAGTAC  GGATGGAGAA  GATGAAGACC  GGATTACTCC  GAATATTATT  1080
1081  AAGCCAGATA  TTGTATTTTT  TGGTGAAGCA  TTGAGTGACC  AATTTTTTGA  TTGCTTTGAA  1140
1141  TCAGATAGAG  AAACGGCTGA  TTTGCTATTG  GTGATAGGAA  CTAGTTTACA  AGTTGCACCA  1200
1201  GTATCTAAAA  TACCGTTTTG  TATTTCAGCA  GAGATTCCTC  AAGTATTGAT  TAATTTGGAA  1260
1261  CCTGTAGGTC  CGTCTGATTG  GTTTGACTTG  GAACTGATTG  GTCCATGTGA  TGTTATTATC  1320
1321  GAACGCTTGT  ATCAATTATT  AGGTTGGCAA  CATGGTATGA  ATCATGTGGG  ATGTTTCAAA  1380
1381  GAGGAACAAG  TACAGCCTCG  AAGATTTGCA  TTCCAAAGAG  ACATAAAATA  A  1431

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Cym-0764Cyanidioschyzon merolae44.958e-76 251
LLPS-Drm-1656Drosophila melanogaster44.781e-71 248
LLPS-Icp-2984Ictalurus punctatus44.632e-69 241
LLPS-Cii-0935Ciona intestinalis44.522e-71 246
LLPS-Orn-0101Oreochromis niloticus44.37e-70 241
LLPS-Tag-3327Taeniopygia guttata44.191e-70 241
LLPS-Pes-1061Pelodiscus sinensis43.966e-70 240
LLPS-Xim-0149Xiphophorus maculatus43.961e-68 238
LLPS-Anp-0792Anas platyrhynchos43.853e-70 241
LLPS-Aon-1163Aotus nancymaae43.714e-69 240
LLPS-Pof-1120Poecilia formosa43.625e-69 239
LLPS-Ten-0311Tetraodon nigroviridis43.522e-70 239
LLPS-Meg-0424Meleagris gallopavo43.527e-70 239
LLPS-Tar-3726Takifugu rubripes43.521e-69 241
LLPS-Caj-4267Callithrix jacchus43.273e-69 241
LLPS-Scm-2803Scophthalmus maximus43.142e-67 235
LLPS-Gaga-2135Gallus gallus43.093e-68 239
LLPS-Fia-0351Ficedula albicollis43.094e-69 238
LLPS-Ict-1565Ictidomys tridecemlineatus43.054e-69 237
LLPS-Rhb-3047Rhinopithecus bieti43.058e-68 236
LLPS-Dio-0970Dipodomys ordii43.052e-68 237
LLPS-Ran-1342Rattus norvegicus43.054e-67 234
LLPS-Paa-2440Papio anubis43.057e-68 237
LLPS-Mal-3143Mandrillus leucophaeus43.052e-68 237
LLPS-Aim-2169Ailuropoda melanoleuca43.056e-69 237
LLPS-Myl-3057Myotis lucifugus43.055e-69 238
LLPS-Mea-1506Mesocricetus auratus43.053e-68 237
LLPS-Chs-4589Chlorocebus sabaeus43.056e-68 237
LLPS-Cea-2499Cercocebus atys43.051e-67 236
LLPS-Fud-1676Fukomys damarensis43.051e-68 236
LLPS-Dar-3439Danio rerio42.959e-69 239
LLPS-Mod-2828Monodelphis domestica42.952e-68 238
LLPS-Orl-3170Oryzias latipes42.951e-68 238
LLPS-Asm-2362Astyanax mexicanus42.952e-69 242
LLPS-Xet-0889Xenopus tropicalis42.689e-71 244
LLPS-Poa-2669Pongo abelii42.636e-68 237
LLPS-Caf-1499Canis familiaris42.635e-68 237
LLPS-Eqc-4554Equus caballus42.633e-68 238
LLPS-Hos-3117Homo sapiens42.635e-68 237
LLPS-Pat-3247Pan troglodytes42.636e-68 237
LLPS-Fec-3373Felis catus42.633e-68 238
LLPS-Man-1184Macaca nemestrina42.638e-68 237
LLPS-Otg-0884Otolemur garnettii42.635e-68 237
LLPS-Mup-4131Mustela putorius furo42.632e-69 238
LLPS-Maf-1133Macaca fascicularis42.638e-68 237
LLPS-Sus-4403Sus scrofa42.634e-68 238
LLPS-Gog-4413Gorilla gorilla42.636e-68 237
LLPS-Leo-3220Lepisosteus oculatus42.521e-66 233
LLPS-Sah-1569Sarcophilus harrisii42.441e-67 233
LLPS-Loa-0232Loxodonta africana42.381e-67 234
LLPS-Anc-2103Anolis carolinensis42.312e-68 236
LLPS-Orc-2802Oryctolagus cuniculus42.317e-68 237
LLPS-Bot-1768Bos taurus42.311e-67 236
LLPS-Ova-4301Ovis aries42.312e-68 236
LLPS-Cogr-0980Colletotrichum graminicola42.281e-68 235
LLPS-Kop-0694Komagataella pastoris42.072e-62 218
LLPS-Urm-1692Ursus maritimus41.788e-41 157
LLPS-Mam-4597Macaca mulatta41.676e-48 177
LLPS-Asn-0828Aspergillus nidulans41.379e-72 242
LLPS-Miv-0765Microbotryum violaceum41.351e-69 239
LLPS-Nol-2802Nomascus leucogenys40.717e-61 217
LLPS-Cog-0869Colletotrichum gloeosporioides40.653e-69 236
LLPS-Cap-2604Cavia porcellus40.621e-67 236
LLPS-Trv-0371Trichoderma virens40.623e-66 228
LLPS-Asc-0090Aspergillus clavatus40.372e-69 235
LLPS-Aso-1150Aspergillus oryzae40.242e-66 227
LLPS-Asf-0151Aspergillus flavus40.243e-66 227
LLPS-Scf-2843Scleropages formosus40.22e-59 212
LLPS-Sac-0630Saccharomyces cerevisiae40.28e-58 206
LLPS-Crn-0785Cryptococcus neoformans40.062e-70 241
LLPS-Usm-1124Ustilago maydis39.825e-59 210
LLPS-Asni-0150Aspergillus niger39.823e-66 227
LLPS-Trr-1159Trichoderma reesei39.812e-62 218
LLPS-Beb-0565Beauveria bassiana39.475e-64 222
LLPS-Blg-1046Blumeria graminis39.364e-66 227
LLPS-Coo-0210Colletotrichum orbiculare39.232e-61 216
LLPS-Ast-1064Aspergillus terreus39.226e-62 223
LLPS-Asfu-0962Aspergillus fumigatus39.021e-64 223
LLPS-Nef-1323Neosartorya fischeri38.724e-64 221
LLPS-Asg-0074Ashbya gossypii38.664e-59 210
LLPS-Dos-1254Dothistroma septosporum38.646e-58 206
LLPS-Fuv-0025Fusarium verticillioides38.513e-65 224
LLPS-Phn-0500Phaeosphaeria nodorum38.463e-57 203
LLPS-Zyt-0442Zymoseptoria tritici38.417e-56 196
LLPS-Scj-0954Schizosaccharomyces japonicus38.153e-57 202
LLPS-Nec-1249Neurospora crassa37.968e-63 222
LLPS-Fuo-1407Fusarium oxysporum37.918e-63 218
LLPS-Pytr-1138Pyrenophora triticirepentis37.92e-58 206
LLPS-Pyt-0496Pyrenophora teres37.92e-59 209
LLPS-Scc-0647Schizosaccharomyces cryophilus37.841e-57 204
LLPS-Mum-2544Mus musculus37.766e-68 237
LLPS-Fus-0683Fusarium solani37.699e-64 220
LLPS-Yal-0904Yarrowia lipolytica37.212e-52 186
LLPS-Lem-0705Leptosphaeria maculans37.072e-56 202
LLPS-Scp-0068Schizosaccharomyces pombe36.996e-60 210
LLPS-Abg-1116Absidia glauca36.975e-63 221
LLPS-Mao-0794Magnaporthe oryzae36.64e-56 201
LLPS-Spr-0265Sporisorium reilianum36.534e-60 212
LLPS-Lac-3103Latimeria chalumnae36.485e-47 177
LLPS-Gag-1161Gaeumannomyces graminis36.317e-55 198
LLPS-Cis-1170Ciona savignyi35.641e-48 177
LLPS-Mel-0939Melampsora laricipopulina35.316e-47 169
LLPS-Pug-0398Puccinia graminis35.293e-41 158
LLPS-Pap-3213Pan paniscus33.656e-44 164
LLPS-Scs-0276Sclerotinia sclerotiorum33.551e-38 151
LLPS-Osl-0677Ostreococcus lucimarinus33.335e-41 155
LLPS-Gaa-2441Gasterosteus aculeatus33.043e-43 162
LLPS-Cas-0352Carlito syrichta32.421e-42 161