LLPS-Gaga-3463
WDR24
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | GATOR complex protein WDR24 |
| Gene Name: | WDR24, RCJMB04_1a19 |
| Ensembl Gene: | ENSGALG00000002450.5 |
| Ensembl Protein: | ENSGALP00000003853.3 |
| Organism: | Gallus gallus |
| Taxa ID: | 9031 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Stress granule | Predicted from orthologs | (View) |
▼ FUNCTION
| As a component of the GATOR complex may function in the amino acid-sensing branch of the TORC1 signaling pathway. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSGALT00000003862.5 | ENSGALP00000003853.3 |
| Ensembl | ENSGALT00000090904.1 | ENSGALP00000070433.1 |
| UniProt | Q5ZMV9, WDR24_CHICK | |
| GeneBank | AJ719275 | CAG30934.1 |
| RefSeq | NM_001030628.1 | NP_001025799.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MEKMARVSTA LGGNTLTGRT MFCHLDAPAN AISVCRDAAQ VVVAGRNIFK IYSIEEEQFV 60 61 EKLNLRVGRK PSLNFSCADV VWHQMDENLL ATAATNGVVV TWNLGKPSRN KQDQLFTEHK 120 121 RTVNKVCFHP TEVYMLLSGS QDGYMKCFDL RKKDSVSTFS GQSESVRDVQ FSIRDYFTFA 180 181 ATFENGNVQL WDIRRPDRYE RMFTAHNGPV FCCDWHPEDR GWLATGGRDK MVKVWDMNTT 240 241 RAKEIYCVQT IASVARVKWR PECKHHIATC SMMVDHNIYV WDVRRPFIPS AMFEEHKDVT 300 301 TGIVWRHLHD PYFLLSGSKD STLYQHIFKD ASQPIDRANP EGLCYSLYGD LAFAAKESLI 360 361 SSDSNRKPYI GDRRHPIFFK RKLDPTEQFE YISSSSALSV FETDVESGSM DWFVHTAKQY 420 421 ALAGRPLAEL CDHNAKVAKG LDRNQVAQTW TMLRIIYSSL GTVSSTNLNH SMGKGSTTLP 480 481 LMNSFNLKDI PSGLGSESRL DRSKGESRTE NILMDSSSTL INNEDNEETE GSDVPADYLL 540 541 GDVEADEDDL YMMDHENPHA EEQEYSLPQE AFPLRHEIVD NPSALDHLQD KADSPHVSGN 600 601 EAETVSLTPV ESFSLISISH SLYENRLPSD FFNPIVRDTL LFYAEQGDVQ TAVSVLIVLG 660 661 DRIRKEIDEQ TQEHWYTSYI DLLQRFQLWN ISNEVIKLST CRAINCLNQA STTLHINCSN 720 721 CKRPMSNRGW ICDRCRQCAS MCAVCHHVVK GLFVWCQGCS HGGHLQHIMK WLETSSHCPA 780 781 GCGHLCEYT 789 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGATGAGA ACCTGCTGGC CACCGCCGCC ACCAATGGCG TGGTGGTCAC CTGGAACCTG 60 61 GGCAAGCCGT CCCGCAATAA GCAGGACCAG CTGTTCACCG AGCACAAGCG CACTGTCAAC 120 121 AAGGTCTGCT TCCACCCCAC CGAGGTGTAC ATGCTGCTCA GCGGCTCCCA GGATGGCTAC 180 181 ATGAAGTGCT TTGACCTGCG CAAGAAGGAC TCTGTCAGCA CCTTCTCTGG CCAGTCGGAG 240 241 AGTGTGCGTG ATGTGCAGTT CAGCATCCGT GACTACTTCA CCTTCGCTGC CACCTTTGAG 300 301 AATGGCAACG TGCAGCTGTG GGACATCCGC CGGCCCGACC GCTATGAGAG GATGTTCACA 360 361 GCCCACAACG GCCCCGTCTT CTGCTGTGAC TGGCACCCCG AGGACCGGGG CTGGCTGGCA 420 421 ACAGGTGGCC GGGATAAGAT GGTGAAGGTT TGGGACATGA ACACCACGCG GGCAAAGGAA 480 481 ATCTACTGCG TGCAGACCAT CGCCTCCGTA GCCCGGGTGA AGTGGCGGCC GGAGTGCAAG 540 541 CACCACATTG CCACCTGCTC CATGATGGTG GACCACAACA TCTACGTCTG GGACGTGCGG 600 601 CGGCCCTTCA TCCCCTCTGC CATGTTTGAG GAGCACAAGG ATGTCACCAC GGGCATCGTG 660 661 TGGCGTCACC TCCACGACCC CTACTTCCTC CTGTCCGGCT CCAAGGACAG TACCCTCTAC 720 721 CAGCACATCT TCAAGGACGC CAGCCAGCCC ATCGACCGGG CCAACCCTGA GGGGCTGTGC 780 781 TACAGCCTTT ATGGAGACCT GGCCTTCGCA GCCAAGGAAA GTCTCATCTC CTCCGACTCC 840 841 AACCGCAAGC CCTACATCGG GGACCGCCGC CACCCCATCT TTTTCAAGCG CAAGCTGGAC 900 901 CCCACGGAGC AGTTTGAGTA CATCTCCTCC TCCAGTGCCC TCAGTGTCTT CGAGACGGAC 960 961 GTGGAGAGTG GCAGCATGGA CTGGTTTGTG CACACTGCCA AGCAGTATGC ACTGGCTGGC 1020 1021 AGGCCCCTGG CTGAGCTCTG CGACCACAAT GCCAAGGTGG CCAAGGGCTT GGACCGCAAC 1080 1081 CAGGTGGCTC AAACGTGGAC GATGCTCCGG ATCATCTACT CCAGCCTTGG CACCGTGTCA 1140 1141 TCCACCAACC TCAATCACAG CATGGGGAAG GGCAGCACCA CTCTCCCGCT CATGAACAGC 1200 1201 TTTAACCTGA AGGACATCCC CTCCGGGCTG GGCAGCGAGT CGAGGTTGGA TCGCAGCAAA 1260 1261 GGAGAAAGCC GCACCGAAAA TATCCTCATG GATTCCTCCT CCACCCTGAT CAACAACGAG 1320 1321 GACAACGAGG AGACAGAGGG CAGCGATGTC CCTGCAGACT ACCTGCTGGG AGACGTGGAG 1380 1381 GCGGATGAAG ATGACCTGTA TATGATGGAC CACGAGAACC CACACGCAGA AGAGCAGGAG 1440 1441 TATAGCCTTC CCCAGGAAGC CTTCCCCCTG CGCCACGAAA TCGTGGACAA CCCGTCAGCC 1500 1501 CTGGACCACC TGCAGGACAA GGCTGACTCC CCCCACGTCA GTGGCAATGA GGCCGAGACG 1560 1561 GTGTCCCTGA CGCCCGTGGA GTCCTTCTCC CTCATCTCCA TCTCCCACTC GCTCTATGAG 1620 1621 AACCGCCTGC CCTCCGACTT CTTCAACCCC ATTGTGCGTG ACACGCTGCT CTTCTACGCC 1680 1681 GAACAAGGGG ACGTGCAGAC AGCTGTGTCT GTGCTCATTG TGCTGGGAGA CCGAATCCGC 1740 1741 AAGGAGATCG ATGAGCAGAC CCAGGAGCAC TGGTACACCT CCTACATCGA CCTGCTGCAG 1800 1801 CGCTTCCAGC TCTGGAACAT CTCCAACGAG GTGATCAAGC TGAGCACGTG CCGCGCCATC 1860 1861 AACTGCCTCA ACCAAGCCTC CACCACCCTC CACATCAACT GCAGCAACTG CAAGCGGCCC 1920 1921 ATGAGCAACA GGGGCTGGAT CTGTGACAGG TGTCGGCAGT GTGCCAGCAT GTGCGCCGTG 1980 1981 TGCCACCACG TGGTGAAGGG GCTCTTTGTC TGGTGCCAGG GCTGCAGCCA CGGCGGCCAC 2040 2041 CTGCAGCACA TCATGAAGTG GTTGGAGACC AGCTCACACT GCCCGGCGGG CTGCGGCCAC 2100 2101 CTCTGCGAGT ACACCTGA 2118 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Lysosomal membrane | |
Biological Process | Autophagy | |
Biological Process | Positive regulation of TOR signaling |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Meg-1378 | Meleagris gallopavo | 100.0 | 0.0 | 1487 |
| LLPS-Fia-3670 | Ficedula albicollis | 98.86 | 0.0 | 1650 |
| LLPS-Sah-4002 | Sarcophilus harrisii | 96.91 | 4e-98 | 330 |
| LLPS-Pes-1939 | Pelodiscus sinensis | 95.44 | 0.0 | 1598 |
| LLPS-Ova-2589 | Ovis aries | 92.44 | 2e-161 | 475 |
| LLPS-Anc-1349 | Anolis carolinensis | 91.59 | 0.0 | 674 |
| LLPS-Mod-3648 | Monodelphis domestica | 90.37 | 0.0 | 1521 |
| LLPS-Mam-2555 | Macaca mulatta | 90.06 | 2e-89 | 307 |
| LLPS-Cea-4717 | Cercocebus atys | 90.06 | 2e-89 | 308 |
| LLPS-Xet-2194 | Xenopus tropicalis | 85.0 | 0.0 | 1227 |
| LLPS-Lac-0452 | Latimeria chalumnae | 83.63 | 0.0 | 1394 |
| LLPS-Ran-0962 | Rattus norvegicus | 83.57 | 0.0 | 1401 |
| LLPS-Mea-3518 | Mesocricetus auratus | 83.44 | 0.0 | 1397 |
| LLPS-Cap-1668 | Cavia porcellus | 83.19 | 0.0 | 1407 |
| LLPS-Mum-3364 | Mus musculus | 83.19 | 0.0 | 1395 |
| LLPS-Ict-2322 | Ictidomys tridecemlineatus | 83.16 | 0.0 | 1410 |
| LLPS-Eqc-2835 | Equus caballus | 83.1 | 0.0 | 1392 |
| LLPS-Mup-1425 | Mustela putorius furo | 82.93 | 0.0 | 1405 |
| LLPS-Cas-0389 | Carlito syrichta | 82.81 | 0.0 | 1407 |
| LLPS-Bot-4778 | Bos taurus | 82.81 | 0.0 | 1404 |
| LLPS-Fec-0272 | Felis catus | 82.55 | 0.0 | 1402 |
| LLPS-Aim-2929 | Ailuropoda melanoleuca | 82.55 | 0.0 | 1380 |
| LLPS-Chs-3767 | Chlorocebus sabaeus | 82.43 | 0.0 | 1403 |
| LLPS-Fud-2598 | Fukomys damarensis | 82.05 | 0.0 | 1395 |
| LLPS-Sus-3621 | Sus scrofa | 81.92 | 0.0 | 1390 |
| LLPS-Dio-1533 | Dipodomys ordii | 81.79 | 0.0 | 1359 |
| LLPS-Leo-2704 | Lepisosteus oculatus | 81.67 | 0.0 | 1356 |
| LLPS-Urm-1938 | Ursus maritimus | 81.6 | 0.0 | 1141 |
| LLPS-Loa-2308 | Loxodonta africana | 81.42 | 0.0 | 1389 |
| LLPS-Scf-1137 | Scleropages formosus | 80.89 | 0.0 | 1356 |
| LLPS-Rhb-1111 | Rhinopithecus bieti | 80.38 | 0.0 | 1101 |
| LLPS-Scm-3791 | Scophthalmus maximus | 79.45 | 0.0 | 1329 |
| LLPS-Gaa-1284 | Gasterosteus aculeatus | 79.45 | 0.0 | 1315 |
| LLPS-Orn-2866 | Oreochromis niloticus | 78.91 | 0.0 | 1322 |
| LLPS-Ten-1423 | Tetraodon nigroviridis | 78.54 | 0.0 | 1294 |
| LLPS-Tar-1318 | Takifugu rubripes | 78.44 | 0.0 | 1306 |
| LLPS-Orl-3282 | Oryzias latipes | 78.31 | 0.0 | 1312 |
| LLPS-Pof-3255 | Poecilia formosa | 77.46 | 0.0 | 1280 |
| LLPS-Xim-0964 | Xiphophorus maculatus | 77.33 | 0.0 | 1277 |
| LLPS-Poa-4367 | Pongo abelii | 77.08 | 0.0 | 1320 |
| LLPS-Otg-1073 | Otolemur garnettii | 76.74 | 0.0 | 1368 |
| LLPS-Asm-2134 | Astyanax mexicanus | 75.47 | 0.0 | 1249 |
| LLPS-Dar-2709 | Danio rerio | 74.75 | 0.0 | 1222 |
| LLPS-Icp-3735 | Ictalurus punctatus | 72.6 | 0.0 | 1200 |
| LLPS-Abg-1026 | Absidia glauca | 41.77 | 3e-36 | 150 |
| LLPS-Drm-2024 | Drosophila melanogaster | 38.11 | 1e-170 | 519 |
| LLPS-Cii-2217 | Ciona intestinalis | 38.07 | 5e-146 | 456 |
| LLPS-Cis-1552 | Ciona savignyi | 36.4 | 1e-140 | 441 |
| LLPS-Tum-1626 | Tuber melanosporum | 34.68 | 1e-68 | 250 |
| LLPS-Kop-1118 | Komagataella pastoris | 34.26 | 1e-36 | 153 |
| LLPS-Trr-1216 | Trichoderma reesei | 33.33 | 3e-06 | 55.1 |
| LLPS-Mae-1255 | Manihot esculenta | 30.43 | 1e-13 | 79.3 |
| LLPS-Orgl-1541 | Oryza glumaepatula | 30.27 | 2e-15 | 85.1 |
| LLPS-Lem-1628 | Leptosphaeria maculans | 30.03 | 1e-36 | 153 |
| LLPS-Tag-3269 | Taeniopygia guttata | 29.82 | 1e-13 | 78.6 |
| LLPS-Ors-2384 | Oryza sativa | 29.73 | 7e-15 | 83.2 |
| LLPS-Lep-0914 | Leersia perrieri | 29.73 | 5e-15 | 83.6 |
| LLPS-Coo-1158 | Colletotrichum orbiculare | 29.7 | 5e-06 | 54.7 |
| LLPS-Orbr-0405 | Oryza brachyantha | 29.69 | 7e-21 | 99.0 |
| LLPS-Orp-1537 | Oryza punctata | 29.69 | 1e-21 | 101 |
| LLPS-Org-2280 | Oryza glaberrima | 29.69 | 3e-21 | 100 |
| LLPS-Orr-1338 | Oryza rufipogon | 29.69 | 3e-21 | 100 |
| LLPS-Orm-0583 | Oryza meridionalis | 29.69 | 2e-21 | 100 |
| LLPS-Orni-2267 | Oryza nivara | 29.69 | 2e-21 | 100 |
| LLPS-Orb-0817 | Oryza barthii | 29.69 | 2e-21 | 100 |
| LLPS-Ori-1639 | Oryza indica | 29.69 | 2e-21 | 100 |
| LLPS-Phn-0446 | Phaeosphaeria nodorum | 29.66 | 4e-36 | 151 |
| LLPS-Put-1009 | Puccinia triticina | 29.41 | 7e-16 | 86.3 |
| LLPS-Pug-0407 | Puccinia graminis | 29.39 | 7e-17 | 89.4 |
| LLPS-Nef-1188 | Neosartorya fischeri | 29.21 | 1e-35 | 150 |
| LLPS-Asfu-1469 | Aspergillus fumigatus | 29.21 | 4e-35 | 148 |
| LLPS-Aso-1557 | Aspergillus oryzae | 29.16 | 2e-37 | 155 |
| LLPS-Fus-0819 | Fusarium solani | 29.13 | 2e-06 | 56.2 |
| LLPS-Pyt-1421 | Pyrenophora teres | 29.02 | 3e-35 | 149 |
| LLPS-Sac-0638 | Saccharomyces cerevisiae | 28.98 | 2e-13 | 78.6 |
| LLPS-Asc-1654 | Aspergillus clavatus | 28.93 | 9e-36 | 150 |
| LLPS-Brd-1816 | Brachypodium distachyon | 28.75 | 6e-22 | 102 |
| LLPS-Scs-0964 | Sclerotinia sclerotiorum | 28.73 | 1e-33 | 143 |
| LLPS-Cus-2188 | Cucumis sativus | 28.64 | 7e-16 | 86.3 |
| LLPS-Dos-0932 | Dothistroma septosporum | 28.49 | 2e-36 | 152 |
| LLPS-Gas-0651 | Galdieria sulphuraria | 28.47 | 8e-48 | 184 |
| LLPS-Mua-0884 | Musa acuminata | 28.44 | 9e-22 | 101 |
| LLPS-Asni-0680 | Aspergillus niger | 28.38 | 2e-36 | 152 |
| LLPS-Sei-1262 | Setaria italica | 28.38 | 2e-16 | 85.5 |
| LLPS-Zyt-1566 | Zymoseptoria tritici | 28.29 | 6e-37 | 154 |
| LLPS-Viv-1827 | Vitis vinifera | 28.18 | 1e-14 | 82.0 |
| LLPS-Amt-1924 | Amborella trichopoda | 28.07 | 2e-21 | 100 |
| LLPS-Zem-0342 | Zea mays | 27.95 | 7e-19 | 92.8 |
| LLPS-Glm-2113 | Glycine max | 27.83 | 7e-15 | 83.2 |
| LLPS-Ast-0695 | Aspergillus terreus | 27.81 | 4e-36 | 151 |
| LLPS-Brn-3138 | Brassica napus | 27.73 | 3e-13 | 77.8 |
| LLPS-Met-1770 | Medicago truncatula | 27.73 | 5e-16 | 86.7 |
| LLPS-Mao-0303 | Magnaporthe oryzae | 27.71 | 7e-16 | 86.7 |
| LLPS-Bro-0139 | Brassica oleracea | 27.53 | 3e-13 | 77.4 |
| LLPS-Php-1887 | Physcomitrella patens | 27.4 | 2e-19 | 94.4 |
| LLPS-Nia-0167 | Nicotiana attenuata | 27.36 | 3e-14 | 81.3 |
| LLPS-Sob-2471 | Sorghum bicolor | 27.36 | 9e-14 | 79.7 |
| LLPS-Tra-1813 | Triticum aestivum | 27.36 | 1e-13 | 79.3 |
| LLPS-Pot-2211 | Populus trichocarpa | 27.27 | 1e-14 | 82.0 |
| LLPS-Brr-2105 | Brassica rapa | 27.27 | 2e-13 | 78.2 |
| LLPS-Prp-1268 | Prunus persica | 27.27 | 6e-15 | 83.2 |
| LLPS-Tru-1879 | Triticum urartu | 27.19 | 2e-14 | 82.0 |
| LLPS-Phv-0388 | Phaseolus vulgaris | 27.11 | 7e-20 | 95.9 |
| LLPS-Asn-0160 | Aspergillus nidulans | 27.11 | 3e-35 | 149 |
| LLPS-Sem-1730 | Selaginella moellendorffii | 27.11 | 3e-17 | 87.8 |
| LLPS-Vir-1032 | Vigna radiata | 27.11 | 4e-20 | 96.7 |
| LLPS-Via-1389 | Vigna angularis | 27.11 | 4e-20 | 96.7 |
| LLPS-Sol-1379 | Solanum lycopersicum | 26.89 | 1e-13 | 79.0 |
| LLPS-Sot-1681 | Solanum tuberosum | 26.89 | 6e-14 | 79.3 |
| LLPS-Coc-2057 | Corchorus capsularis | 26.82 | 1e-13 | 79.0 |
| LLPS-Thc-1930 | Theobroma cacao | 26.82 | 1e-13 | 79.7 |
| LLPS-Blg-1548 | Blumeria graminis | 26.71 | 1e-22 | 108 |
| LLPS-Dac-2237 | Daucus carota | 26.36 | 4e-14 | 80.9 |
| LLPS-Anp-0565 | Anas platyrhynchos | 26.27 | 2e-17 | 88.2 |
| LLPS-Art-2198 | Arabidopsis thaliana | 26.22 | 2e-19 | 94.7 |
| LLPS-Scc-1268 | Schizosaccharomyces cryophilus | 26.13 | 1e-57 | 215 |
| LLPS-Cogr-0372 | Colletotrichum graminicola | 26.11 | 8e-24 | 112 |
| LLPS-Yal-0583 | Yarrowia lipolytica | 26.03 | 9e-14 | 78.2 |
| LLPS-Arl-0889 | Arabidopsis lyrata | 25.87 | 3e-18 | 90.5 |
| LLPS-Asg-0957 | Ashbya gossypii | 25.82 | 5e-20 | 100 |
| LLPS-Hov-2118 | Hordeum vulgare | 25.79 | 1e-13 | 79.0 |
| LLPS-Hea-0915 | Helianthus annuus | 25.78 | 2e-16 | 85.5 |
| LLPS-Myl-1811 | Myotis lucifugus | 25.63 | 2e-15 | 81.6 |
| LLPS-Orc-0416 | Oryctolagus cuniculus | 25.19 | 6e-17 | 86.7 |
| LLPS-Fuo-1551 | Fusarium oxysporum | 25.12 | 3e-23 | 110 |
| LLPS-Gag-1226 | Gaeumannomyces graminis | 25.06 | 2e-22 | 108 |
| LLPS-Nec-0892 | Neurospora crassa | 25.0 | 4e-22 | 106 |
| LLPS-Mal-2341 | Mandrillus leucophaeus | 24.9 | 9e-16 | 82.8 |
| LLPS-Fuv-1448 | Fusarium verticillioides | 24.83 | 2e-22 | 107 |
| LLPS-Scp-0952 | Schizosaccharomyces pombe | 24.64 | 3e-48 | 187 |
| LLPS-Nol-1101 | Nomascus leucogenys | 24.59 | 1e-15 | 82.8 |
| LLPS-Man-1064 | Macaca nemestrina | 24.44 | 3e-16 | 84.7 |
| LLPS-Pap-1753 | Pan paniscus | 24.44 | 5e-16 | 84.0 |
| LLPS-Caf-0689 | Canis familiaris | 24.44 | 7e-16 | 83.6 |
| LLPS-Maf-4339 | Macaca fascicularis | 24.44 | 3e-16 | 84.7 |
| LLPS-Paa-3889 | Papio anubis | 24.44 | 3e-16 | 84.7 |
| LLPS-Hos-1780 | Homo sapiens | 24.35 | 4e-16 | 84.3 |
| LLPS-Gog-1288 | Gorilla gorilla | 24.35 | 5e-16 | 84.0 |
| LLPS-Osl-0001 | Ostreococcus lucimarinus | 24.34 | 2e-14 | 79.3 |
| LLPS-Chr-1368 | Chlamydomonas reinhardtii | 24.19 | 2e-16 | 85.5 |
| LLPS-Beb-0206 | Beauveria bassiana | 24.11 | 6e-22 | 106 |
| LLPS-Ved-0399 | Verticillium dahliae | 24.11 | 6e-26 | 119 |
| LLPS-Cog-1420 | Colletotrichum gloeosporioides | 24.06 | 7e-21 | 102 |
| LLPS-Gor-0157 | Gossypium raimondii | 24.0 | 1e-17 | 89.4 |
| LLPS-Pat-1210 | Pan troglodytes | 23.99 | 8e-16 | 83.6 |
| LLPS-Caj-1842 | Callithrix jacchus | 23.99 | 1e-14 | 80.5 |
| LLPS-Aon-4414 | Aotus nancymaae | 23.99 | 8e-15 | 81.3 |
| LLPS-Trv-1140 | Trichoderma virens | 23.3 | 3e-15 | 84.7 |
| LLPS-Mel-0085 | Melampsora laricipopulina | 22.99 | 1e-18 | 94.0 |