• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Gaga-2295
YARS

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Tyrosine--tRNA ligase; Tyrosyl-tRNA synthetase
Gene Name: YARS
Ensembl Gene: ENSGALG00000003563.6
Ensembl Protein: ENSGALP00000005633.4
Organism: Gallus gallus
Taxa ID: 9031
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Stress granule, Postsynaptic densityPredicted from orthologs(View)

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MQPGHAAAAM  ETASGPQEKY  QLITRNLQEV  LGEDKLMAIL  KEREVKIYWG  TATTGKPHVA  60
61    YFVPMSKIAD  FLKAGCEVTI  LFADLHAYLD  NMKAPWELLE  LRTRYYEHVI  KAMLESIGVP  120
121   LEKLKFIRGT  DYQLSKEYTL  DVYRLSSVVT  QHDAKKAGAE  VVKQVEHPLL  SGLLYPGLQA  180
181   LDEEYLKVDA  QFGGVDQRKI  FTFAEKYLPS  LGYAKRIHLM  NPMVPGLTGS  KMSSSEEDSK  240
241   IDLLDRKEDV  KKKLKKAFCE  PGNIENNGVL  SFIKHVLFPL  KSEFVILREE  KWGGNKTYTA  300
301   YETLEKDFAE  QVVHPGDLKN  SVEVALNKLL  DPIREKFNSP  ELKKLTNAAY  PNPSKAKPAE  360
361   KGTKNSEPET  IVPSRLDIRV  GKVVSVEKHP  DADSLYVEKI  DVGEPEPRTV  VSGLVQFVPK  420
421   EQLQDRLVVL  LCNLKPQKMR  GVESQGMVLC  ASSVGEPRQV  EPLDPPAECC  AGERVYVEGY  480
481   EDGEPDDELK  PKKKVFEKLQ  ADFRISEDCI  AQWKERNFLT  KLGSISCKSL  KGGSIS  536
Nucleotide CDS Sequence (FASTA)
1     ATGCAACCCG  GGCACGCCGC  TGCCGCCATG  GAGACCGCGT  CCGGTCCGCA  GGAGAAGTAC  60
61    CAGCTCATCA  CCCGCAACCT  GCAGGAGGTG  CTGGGTGAGG  ATAAGCTGAT  GGCCATCCTG  120
121   AAGGAGCGGG  AGGTGAAGAT  CTACTGGGGC  ACTGCCACCA  CGGGCAAGCC  GCACGTTGCC  180
181   TACTTCGTGC  CCATGTCCAA  GATCGCCGAC  TTCCTGAAGG  CTGGCTGTGA  GGTGACGATC  240
241   CTCTTTGCTG  ACCTCCACGC  TTACCTAGAC  AACATGAAGG  CCCCCTGGGA  GCTGCTGGAG  300
301   TTGCGCACTC  GCTATTATGA  GCATGTGATC  AAAGCCATGC  TGGAGAGCAT  TGGAGTGCCC  360
361   CTGGAAAAGC  TGAAGTTCAT  CCGAGGCACG  GACTACCAGC  TCAGCAAGGA  GTACACGTTG  420
421   GATGTGTACC  GTTTGTCATC  TGTGGTGACA  CAGCATGATG  CAAAGAAGGC  AGGAGCAGAG  480
481   GTGGTGAAGC  AGGTGGAGCA  TCCTTTGTTG  AGCGGCTTGC  TCTACCCAGG  CCTGCAGGCC  540
541   CTGGACGAGG  AATACCTCAA  GGTCGATGCA  CAGTTTGGAG  GAGTTGATCA  AAGGAAGATA  600
601   TTCACCTTTG  CAGAGAAGTA  CCTTCCTTCC  CTGGGCTATG  CCAAGCGCAT  CCACTTGATG  660
661   AATCCAATGG  TTCCCGGTCT  GACAGGCAGC  AAAATGAGCT  CATCAGAAGA  GGACTCGAAA  720
721   ATTGATCTTC  TGGACCGCAA  AGAAGATGTG  AAGAAAAAGC  TGAAGAAGGC  TTTCTGTGAG  780
781   CCAGGGAATA  TAGAGAACAA  TGGTGTCCTC  TCCTTCATTA  AGCACGTCCT  CTTTCCCCTC  840
841   AAGTCAGAGT  TTGTGATTCT  GCGAGAAGAA  AAATGGGGAG  GAAACAAAAC  ATACACAGCC  900
901   TATGAAACTC  TGGAGAAGGA  CTTTGCTGAG  CAGGTTGTGC  ATCCTGGAGA  CCTGAAGAAC  960
961   TCTGTGGAAG  TGGCCCTGAA  TAAGCTGCTT  GACCCCATCA  GGGAGAAATT  CAACAGCCCA  1020
1021  GAGCTGAAGA  AGTTGACCAA  CGCAGCATAT  CCTAACCCAT  CCAAAGCAAA  GCCTGCAGAG  1080
1081  AAAGGCACCA  AGAACTCAGA  GCCAGAGACT  ATTGTCCCAT  CTCGGCTGGA  CATCCGTGTT  1140
1141  GGCAAAGTGG  TCAGTGTGGA  AAAGCACCCA  GATGCTGACA  GCCTGTATGT  GGAGAAGATC  1200
1201  GATGTGGGTG  AGCCTGAGCC  CCGCACTGTG  GTCAGTGGCC  TGGTGCAGTT  TGTCCCTAAG  1260
1261  GAGCAGCTGC  AGGACAGGCT  CGTGGTGCTG  CTTTGTAACC  TCAAGCCTCA  GAAGATGAGG  1320
1321  GGCGTGGAGT  CACAGGGCAT  GGTGCTGTGT  GCCTCCAGTG  TGGGGGAGCC  ACGGCAGGTG  1380
1381  GAGCCCCTGG  ACCCACCTGC  TGAGTGCTGC  GCTGGGGAGC  GTGTCTACGT  GGAGGGCTAC  1440
1441  GAGGATGGGG  AGCCTGATGA  TGAGCTCAAG  CCAAAGAAGA  AGGTGTTTGA  GAAGCTACAG  1500
1501  GCTGATTTTC  GCATCTCTGA  GGACTGCATC  GCTCAGTGGA  AGGAGAGAAA  CTTTCTGACC  1560
1561  AAGCTGGGGA  GCATCTCGTG  TAAAAGCCTG  AAGGGGGGGA  GCATCAGCTA  A  1611

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Meg-0614Meleagris gallopavo97.450.0 985
LLPS-Fia-2326Ficedula albicollis94.810.0 986
LLPS-Tag-1386Taeniopygia guttata94.50.0 996
LLPS-Fec-0407Felis catus91.676e-146 435
LLPS-Anp-0494Anas platyrhynchos88.780.0 891
LLPS-Mea-0069Mesocricetus auratus88.30.0 887
LLPS-Mup-3252Mustela putorius furo88.143e-104 319
LLPS-Otg-1215Otolemur garnettii88.070.0 922
LLPS-Aon-2841Aotus nancymaae88.070.0 908
LLPS-Chs-2921Chlorocebus sabaeus88.070.0 910
LLPS-Paa-1419Papio anubis88.070.0 909
LLPS-Mam-2873Macaca mulatta87.880.0 908
LLPS-Cas-0240Carlito syrichta87.690.0 902
LLPS-Mal-3003Mandrillus leucophaeus87.690.0 903
LLPS-Cea-3654Cercocebus atys87.430.0 911
LLPS-Ova-2844Ovis aries87.330.0 907
LLPS-Hos-1305Homo sapiens87.310.0 903
LLPS-Aim-0280Ailuropoda melanoleuca87.310.0 903
LLPS-Orc-1361Oryctolagus cuniculus87.120.0 905
LLPS-Sus-3850Sus scrofa87.120.0 906
LLPS-Myl-0251Myotis lucifugus87.120.0 903
LLPS-Pat-1579Pan troglodytes87.050.0 904
LLPS-Pap-1328Pan paniscus87.050.0 904
LLPS-Nol-2003Nomascus leucogenys87.030.0 906
LLPS-Mum-4546Mus musculus87.010.0 905
LLPS-Caj-4543Callithrix jacchus86.930.0 900
LLPS-Bot-1066Bos taurus86.930.0 899
LLPS-Ict-1059Ictidomys tridecemlineatus86.790.0 902
LLPS-Eqc-1493Equus caballus86.780.0 906
LLPS-Cap-2849Cavia porcellus86.420.0 913
LLPS-Gog-1019Gorilla gorilla86.330.0 901
LLPS-Caf-4065Canis familiaris86.120.0 902
LLPS-Ran-0855Rattus norvegicus86.060.0 902
LLPS-Fud-2437Fukomys damarensis86.040.0 892
LLPS-Dio-3812Dipodomys ordii85.980.0 889
LLPS-Anc-1165Anolis carolinensis85.770.0 887
LLPS-Tut-2071Tursiops truncatus85.610.0 889
LLPS-Loa-2452Loxodonta africana85.390.0 895
LLPS-Poa-0189Pongo abelii85.310.0 865
LLPS-Sah-0699Sarcophilus harrisii85.230.0 885
LLPS-Leo-2890Lepisosteus oculatus82.920.0 855
LLPS-Maf-4019Macaca fascicularis82.580.0 843
LLPS-Xet-1991Xenopus tropicalis82.570.0 867
LLPS-Man-3979Macaca nemestrina82.420.0 821
LLPS-Dar-0430Danio rerio81.070.0 843
LLPS-Lac-0541Latimeria chalumnae80.460.0 855
LLPS-Scf-1368Scleropages formosus80.310.0 835
LLPS-Asm-0863Astyanax mexicanus80.150.0 851
LLPS-Ora-1319Ornithorhynchus anatinus79.40.0 733
LLPS-Urm-0904Ursus maritimus78.730.0 793
LLPS-Tar-1958Takifugu rubripes78.560.0 830
LLPS-Ten-1308Tetraodon nigroviridis78.460.0 827
LLPS-Orl-3739Oryzias latipes78.290.0 820
LLPS-Icp-1084Ictalurus punctatus77.760.0 804
LLPS-Pof-1360Poecilia formosa77.380.0 816
LLPS-Xim-2442Xiphophorus maculatus76.670.0 771
LLPS-Gaa-1572Gasterosteus aculeatus76.650.0 810
LLPS-Scm-3720Scophthalmus maximus76.110.0 792
LLPS-Pes-2875Pelodiscus sinensis75.760.0 739
LLPS-Rhb-3233Rhinopithecus bieti75.352e-127 382
LLPS-Orn-0305Oreochromis niloticus75.330.0 818
LLPS-Cii-0637Ciona intestinalis69.830.0 725
LLPS-Abg-1385Absidia glauca69.598e-161 470
LLPS-Drm-0986Drosophila melanogaster69.410.0 692
LLPS-Cis-2093Ciona savignyi65.730.0 664
LLPS-Scj-0901Schizosaccharomyces japonicus61.471e-133 401
LLPS-Asg-0746Ashbya gossypii58.642e-133 401
LLPS-Tum-0974Tuber melanosporum58.55e-132 398
LLPS-Yal-0393Yarrowia lipolytica58.171e-133 401
LLPS-Sac-0404Saccharomyces cerevisiae57.473e-131 395
LLPS-Scc-0577Schizosaccharomyces cryophilus57.435e-129 389
LLPS-Kop-0307Komagataella pastoris57.263e-130 393
LLPS-Scp-1048Schizosaccharomyces pombe56.232e-129 390
LLPS-Cae-1088Caenorhabditis elegans55.683e-99 322
LLPS-Trr-0697Trichoderma reesei55.499e-110 339
LLPS-Php-1913Physcomitrella patens55.491e-43 169
LLPS-Usm-0508Ustilago maydis54.748e-122 374
LLPS-Asc-1192Aspergillus clavatus54.62e-111 344
LLPS-Put-1205Puccinia triticina54.264e-112 346
LLPS-Gas-0984Galdieria sulphuraria53.992e-44 166
LLPS-Nef-0035Neosartorya fischeri53.962e-108 336
LLPS-Spr-0791Sporisorium reilianum53.84e-119 366
LLPS-Trv-1253Trichoderma virens53.713e-114 351
LLPS-Mel-0436Melampsora laricipopulina53.692e-41 159
LLPS-Asfu-1434Aspergillus fumigatus53.674e-108 335
LLPS-Scs-0298Sclerotinia sclerotiorum53.262e-107 334
LLPS-Asni-0488Aspergillus niger52.796e-108 335
LLPS-Pot-2138Populus trichocarpa52.781e-44 172
LLPS-Mao-1125Magnaporthe oryzae52.772e-107 333
LLPS-Chr-0102Chlamydomonas reinhardtii52.765e-42 166
LLPS-Beb-0260Beauveria bassiana52.725e-110 340
LLPS-Cogr-0953Colletotrichum graminicola52.728e-107 332
LLPS-Mod-1685Monodelphis domestica52.444e-47 172
LLPS-Gag-0905Gaeumannomyces graminis52.344e-105 327
LLPS-Pug-0828Puccinia graminis52.32e-113 351
LLPS-Miv-0677Microbotryum violaceum52.282e-111 345
LLPS-Dac-2038Daucus carota52.275e-43 169
LLPS-Zyt-0081Zymoseptoria tritici52.242e-99 314
LLPS-Asn-0526Aspergillus nidulans52.161e-108 337
LLPS-Coo-1283Colletotrichum orbiculare52.152e-106 331
LLPS-Ere-0736Erinaceus europaeus52.026e-48 173
LLPS-Asf-0170Aspergillus flavus51.871e-105 328
LLPS-Map-0264Magnaporthe poae51.759e-103 321
LLPS-Fus-1389Fusarium solani51.671e-108 337
LLPS-Aso-0598Aspergillus oryzae51.624e-102 321
LLPS-Phn-1028Phaeosphaeria nodorum51.322e-106 333
LLPS-Sob-1056Sorghum bicolor50.918e-40 159
LLPS-Nec-0820Neurospora crassa50.883e-103 323
LLPS-Lem-0263Leptosphaeria maculans50.889e-106 331
LLPS-Blg-0471Blumeria graminis50.586e-102 320
LLPS-Mua-1991Musa acuminata50.575e-45 162
LLPS-Pyt-1378Pyrenophora teres50.422e-100 318
LLPS-Tru-0199Triticum urartu50.354e-33 139
LLPS-Sem-0785Selaginella moellendorffii50.271e-37 152
LLPS-Dos-0822Dothistroma septosporum50.09e-106 330
LLPS-Pytr-1327Pyrenophora triticirepentis50.03e-98 312
LLPS-Brr-0225Brassica rapa49.734e-43 168
LLPS-Bro-1018Brassica oleracea49.731e-43 169
LLPS-Brn-1172Brassica napus49.731e-43 169
LLPS-Prp-1259Prunus persica49.459e-44 170
LLPS-Sei-0553Setaria italica49.175e-41 162
LLPS-Met-1261Medicago truncatula49.132e-41 163
LLPS-Crn-1057Cryptococcus neoformans48.941e-106 344
LLPS-Viv-1796Vitis vinifera48.156e-38 153
LLPS-Fuv-1038Fusarium verticillioides48.111e-109 339
LLPS-Lep-0439Leersia perrieri47.592e-39 149
LLPS-Zem-1083Zea mays47.519e-39 155
LLPS-Via-1347Vigna angularis47.42e-33 134
LLPS-Fuo-0970Fusarium oxysporum47.372e-108 337
LLPS-Nia-2167Nicotiana attenuata47.23e-45 174
LLPS-Phv-0196Phaseolus vulgaris46.962e-34 138
LLPS-Ors-0185Oryza sativa46.23e-38 145
LLPS-Glm-1904Glycine max46.112e-33 135
LLPS-Tra-1821Triticum aestivum45.835e-40 159
LLPS-Cog-0845Colletotrichum gloeosporioides45.664e-69 233
LLPS-Hov-1168Hordeum vulgare45.63e-40 160
LLPS-Ast-1324Aspergillus terreus45.544e-80 261
LLPS-Cym-1073Cyanidioschyzon merolae40.14e-33 134
LLPS-Ved-0342Verticillium dahliae37.534e-63 218
LLPS-Cus-1482Cucumis sativus33.432e-35 140
LLPS-Gor-2509Gossypium raimondii33.044e-35 140
LLPS-Thc-2273Theobroma cacao31.754e-33 134
LLPS-Amt-1637Amborella trichopoda30.872e-33 135
LLPS-Orp-2365Oryza punctata30.112e-35 141
LLPS-Org-1783Oryza glaberrima30.02e-35 141
LLPS-Ori-0216Oryza indica30.02e-35 141
LLPS-Orbr-1101Oryza brachyantha29.752e-34 138
LLPS-Orm-0386Oryza meridionalis29.722e-35 141
LLPS-Orb-0496Oryza barthii29.563e-34 137
LLPS-Orr-0620Oryza rufipogon28.736e-34 136
LLPS-Orni-1529Oryza nivara28.736e-34 136
LLPS-Orgl-1670Oryza glumaepatula28.736e-34 136