• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Aim-0280
YARS

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Tyrosine--tRNA ligase; Tyrosyl-tRNA synthetase
Gene Name: YARS
Ensembl Gene: ENSAMEG00000007476.1
Ensembl Protein: ENSAMEP00000007916.1
Organism: Ailuropoda melanoleuca
Taxa ID: 9646
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Stress granule, Postsynaptic densityPredicted from orthologs(View)

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MGDAPSPEEK  LHLITRNLQE  VLGEEKLKEV  LKERELKVYW  GTATTGKPHV  AYFVPMSKIA  60
61    DFLKAGCEVT  ILFADLHAYL  DNMKAPWELL  ELRTNYYENV  IKAMLESIGV  PLEKLKFVKG  120
121   TDYQLSKEYT  LDVYRLSSVV  TQHDAKKAGA  EVVKQVEHPL  LSGLLYPGLQ  ALDEEYLKVD  180
181   AQFGGVDQRK  IFTFAEKYLP  ALGYSKRVHL  MNPMVPGLTG  SKMSSSEEES  KIDLLDRKED  240
241   VKKKLKKAFC  EPGNVENNGV  LSFIKHVLFP  LKSEFVILRD  EKWGGNKTYT  TYLDLEKDFA  300
301   DEVVHPGDLK  NSVEVALNKL  LDPIREKFNT  PALKKLTSAA  YPEPSKQKPV  AKGPAKNSEP  360
361   EEVIPSRLDI  RVGKVISVDK  HPDADSLYVE  KIDVGEAEPR  TVVSGLVQFV  PKEELQDRLV  420
421   VVLCNLKPQK  MRGVESQGML  LCASLEGVDR  KVEPLDPPAG  SAPGERVFVK  GYEKGQPDEE  480
481   LKPKKKVFEK  LQADFKTSED  CIAQWKQTNF  MTKLGCISCK  SLKGGNIS  528
Nucleotide CDS Sequence (FASTA)
1     ATGGGGGACG  CTCCGAGCCC  TGAAGAGAAG  CTGCACCTTA  TCACCCGGAA  CCTGCAGGAG  60
61    GTTCTGGGGG  AAGAGAAGCT  GAAGGAGGTA  CTCAAGGAGC  GGGAACTTAA  AGTTTACTGG  120
121   GGAACAGCAA  CCACAGGCAA  GCCACATGTG  GCTTACTTCG  TGCCTATGTC  TAAGATTGCG  180
181   GACTTCCTAA  AAGCAGGATG  TGAGGTAACG  ATTCTGTTTG  CGGACCTTCA  CGCATACCTG  240
241   GATAACATGA  AAGCTCCATG  GGAACTTCTA  GAACTCCGAA  CCAACTACTA  TGAGAATGTG  300
301   ATCAAGGCAA  TGCTGGAGAG  CATTGGTGTA  CCCCTGGAAA  AGCTCAAGTT  CGTCAAAGGC  360
361   ACTGATTACC  AGCTCAGCAA  AGAGTACACA  CTAGACGTGT  ACAGACTCTC  GTCCGTGGTC  420
421   ACACAGCACG  ACGCCAAGAA  AGCTGGGGCC  GAGGTGGTGA  AGCAGGTGGA  GCACCCTCTG  480
481   CTGAGCGGTC  TGCTGTACCC  TGGATTACAG  GCCTTGGATG  AAGAGTATTT  GAAAGTAGAT  540
541   GCCCAGTTTG  GAGGCGTTGA  TCAGAGAAAG  ATTTTTACCT  TTGCAGAGAA  GTACCTCCCT  600
601   GCACTCGGCT  ACTCAAAACG  GGTCCATCTG  ATGAATCCCA  TGGTTCCAGG  ATTAACTGGC  660
661   AGTAAAATGA  GCTCCTCAGA  AGAGGAGTCC  AAGATTGATC  TCCTTGACCG  GAAGGAGGAT  720
721   GTAAAGAAAA  AACTAAAGAA  GGCCTTCTGT  GAGCCAGGGA  ATGTGGAGAA  CAATGGGGTT  780
781   CTGTCTTTCA  TCAAGCATGT  CCTCTTCCCC  CTGAAGTCCG  AGTTTGTGAT  CCTTCGAGAT  840
841   GAGAAATGGG  GTGGAAACAA  AACCTATACC  ACTTACTTGG  ACCTGGAAAA  GGACTTTGCT  900
901   GATGAGGTTG  TACACCCTGG  AGACCTAAAG  AATTCTGTTG  AAGTCGCCCT  GAACAAGTTG  960
961   CTGGATCCCA  TCCGGGAGAA  GTTTAATACC  CCGGCACTGA  AGAAACTGAC  CAGCGCCGCC  1020
1021  TACCCAGAGC  CCTCCAAGCA  GAAACCAGTT  GCCAAAGGCC  CTGCCAAGAA  TTCGGAACCA  1080
1081  GAGGAGGTCA  TCCCGTCCCG  GCTGGATATC  CGTGTGGGGA  AAGTCATTAG  CGTGGACAAG  1140
1141  CACCCCGATG  CAGACAGCCT  GTACGTGGAG  AAGATTGACG  TGGGGGAAGC  CGAGCCGCGG  1200
1201  ACTGTGGTGA  GCGGCCTGGT  GCAGTTTGTG  CCCAAGGAGG  AGTTGCAGGA  CCGGCTGGTG  1260
1261  GTGGTGCTGT  GCAATCTGAA  ACCCCAGAAG  ATGAGAGGCG  TCGAGTCCCA  GGGCATGCTT  1320
1321  CTGTGCGCCT  CCCTAGAGGG  GGTAGACCGC  AAGGTTGAGC  CTCTGGACCC  TCCTGCAGGC  1380
1381  TCTGCTCCCG  GTGAGCGAGT  GTTCGTGAAG  GGCTACGAGA  AGGGCCAACC  AGATGAAGAG  1440
1441  CTCAAGCCCA  AGAAGAAAGT  CTTTGAGAAG  TTGCAGGCTG  ACTTTAAAAC  CTCTGAGGAT  1500
1501  TGCATCGCAC  AGTGGAAGCA  AACCAACTTC  ATGACCAAGC  TGGGGTGCAT  CTCCTGTAAA  1560
1561  TCGCTGAAAG  GGGGAAACAT  CAGCTAG  1587

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Fec-0407Felis catus98.218e-138 414
LLPS-Caf-4065Canis familiaris97.540.0 964
LLPS-Mup-0496Mustela putorius furo96.860.0 582
LLPS-Sus-3850Sus scrofa96.590.0 954
LLPS-Orc-1361Oryctolagus cuniculus96.40.0 954
LLPS-Ict-1059Ictidomys tridecemlineatus96.210.0 947
LLPS-Myl-0251Myotis lucifugus96.210.0 952
LLPS-Mum-4546Mus musculus96.020.0 948
LLPS-Ova-2844Ovis aries96.020.0 949
LLPS-Mea-0069Mesocricetus auratus95.920.0 916
LLPS-Otg-1215Otolemur garnettii95.830.0 953
LLPS-Loa-2452Loxodonta africana95.830.0 945
LLPS-Pat-1579Pan troglodytes95.640.0 947
LLPS-Pap-1328Pan paniscus95.640.0 947
LLPS-Nol-2003Nomascus leucogenys95.640.0 948
LLPS-Mam-2873Macaca mulatta95.640.0 950
LLPS-Bot-1066Bos taurus95.640.0 945
LLPS-Eqc-1493Equus caballus95.620.0 942
LLPS-Hos-1305Homo sapiens95.450.0 948
LLPS-Cas-0240Carlito syrichta95.450.0 944
LLPS-Chs-2921Chlorocebus sabaeus95.450.0 948
LLPS-Cea-3654Cercocebus atys95.450.0 950
LLPS-Aon-2841Aotus nancymaae95.450.0 949
LLPS-Paa-1419Papio anubis95.450.0 950
LLPS-Tut-2071Tursiops truncatus95.450.0 943
LLPS-Gog-1019Gorilla gorilla95.270.0 945
LLPS-Mal-3003Mandrillus leucophaeus95.080.0 944
LLPS-Caj-4543Callithrix jacchus94.890.0 944
LLPS-Dio-3812Dipodomys ordii94.70.0 933
LLPS-Ran-0855Rattus norvegicus94.510.0 940
LLPS-Cap-2849Cavia porcellus93.940.0 939
LLPS-Fud-2437Fukomys damarensis93.750.0 934
LLPS-Poa-0189Pongo abelii93.410.0 913
LLPS-Sah-0699Sarcophilus harrisii90.530.0 899
LLPS-Meg-0614Meleagris gallopavo90.410.0 858
LLPS-Maf-4019Macaca fascicularis89.960.0 882
LLPS-Man-3979Macaca nemestrina88.660.0 843
LLPS-Urm-0904Ursus maritimus88.640.0 833
LLPS-Fia-2326Ficedula albicollis88.480.0 862
LLPS-Tag-1386Taeniopygia guttata88.070.0 870
LLPS-Gaga-2295Gallus gallus87.310.0 870
LLPS-Anc-1165Anolis carolinensis85.20.0 851
LLPS-Ora-1319Ornithorhynchus anatinus84.240.0 734
LLPS-Leo-2890Lepisosteus oculatus83.870.0 830
LLPS-Anp-0494Anas platyrhynchos83.330.0 776
LLPS-Scf-1368Scleropages formosus82.770.0 814
LLPS-Dar-0430Danio rerio82.420.0 813
LLPS-Asm-0863Astyanax mexicanus81.70.0 820
LLPS-Lac-0541Latimeria chalumnae81.630.0 827
LLPS-Tar-1958Takifugu rubripes80.530.0 788
LLPS-Icp-1084Ictalurus punctatus79.70.0 777
LLPS-Xet-1991Xenopus tropicalis79.360.0 808
LLPS-Ten-1308Tetraodon nigroviridis79.320.0 787
LLPS-Rhb-3233Rhinopithecus bieti78.952e-131 392
LLPS-Orl-3739Oryzias latipes78.860.0 770
LLPS-Gaa-1572Gasterosteus aculeatus78.720.0 786
LLPS-Xim-2442Xiphophorus maculatus78.130.0 724
LLPS-Orn-0305Oreochromis niloticus77.940.0 781
LLPS-Pof-1360Poecilia formosa77.820.0 774
LLPS-Pes-2875Pelodiscus sinensis74.910.0 696
LLPS-Scm-3720Scophthalmus maximus73.480.0 755
LLPS-Cii-0637Ciona intestinalis70.080.0 681
LLPS-Drm-0986Drosophila melanogaster69.790.0 639
LLPS-Cis-2093Ciona savignyi66.850.0 620
LLPS-Abg-1385Absidia glauca66.36e-142 422
LLPS-Scj-0901Schizosaccharomyces japonicus62.12e-119 365
LLPS-Cae-1088Caenorhabditis elegans59.746e-88 292
LLPS-Yal-0393Yarrowia lipolytica58.671e-118 362
LLPS-Tum-0974Tuber melanosporum58.621e-119 366
LLPS-Asg-0746Ashbya gossypii58.074e-118 361
LLPS-Kop-0307Komagataella pastoris57.592e-117 360
LLPS-Sac-0404Saccharomyces cerevisiae56.945e-118 361
LLPS-Trr-0697Trichoderma reesei56.572e-97 307
LLPS-Scp-1048Schizosaccharomyces pombe56.362e-116 357
LLPS-Scc-0577Schizosaccharomyces cryophilus55.753e-112 345
LLPS-Mel-0436Melampsora laricipopulina55.73e-43 164
LLPS-Trv-1253Trichoderma virens54.954e-102 319
LLPS-Ere-0736Erinaceus europaeus54.821e-48 175
LLPS-Usm-0508Ustilago maydis54.742e-113 352
LLPS-Spr-0791Sporisorium reilianum54.572e-110 343
LLPS-Miv-0677Microbotryum violaceum54.193e-98 311
LLPS-Asfu-1434Aspergillus fumigatus54.195e-93 296
LLPS-Sem-0785Selaginella moellendorffii54.091e-38 154
LLPS-Asf-0170Aspergillus flavus53.993e-94 299
LLPS-Nef-0035Neosartorya fischeri53.878e-93 295
LLPS-Beb-0260Beauveria bassiana53.851e-97 308
LLPS-Asn-0526Aspergillus nidulans53.851e-97 308
LLPS-Asc-1192Aspergillus clavatus53.786e-96 303
LLPS-Php-1913Physcomitrella patens53.72e-42 166
LLPS-Aso-0598Aspergillus oryzae53.671e-93 298
LLPS-Cogr-0953Colletotrichum graminicola53.551e-93 298
LLPS-Coo-1283Colletotrichum orbiculare53.553e-95 302
LLPS-Dac-2038Daucus carota53.294e-44 172
LLPS-Zyt-0081Zymoseptoria tritici53.137e-87 281
LLPS-Phn-1028Phaeosphaeria nodorum52.91e-96 307
LLPS-Blg-0471Blumeria graminis52.722e-91 292
LLPS-Mod-1685Monodelphis domestica52.693e-48 176
LLPS-Chr-1207Chlamydomonas reinhardtii52.691e-45 166
LLPS-Nec-0820Neurospora crassa52.582e-93 297
LLPS-Dos-0822Dothistroma septosporum52.228e-89 286
LLPS-Cog-0845Colletotrichum gloeosporioides52.175e-60 209
LLPS-Put-1205Puccinia triticina52.146e-99 312
LLPS-Scs-0298Sclerotinia sclerotiorum52.122e-94 300
LLPS-Lem-0263Leptosphaeria maculans52.034e-99 314
LLPS-Fuo-0970Fusarium oxysporum51.825e-94 299
LLPS-Sob-1056Sorghum bicolor51.813e-41 163
LLPS-Tru-0199Triticum urartu51.752e-34 143
LLPS-Viv-1796Vitis vinifera51.611e-40 160
LLPS-Prp-1259Prunus persica51.452e-43 169
LLPS-Art-0613Arabidopsis thaliana51.38e-35 139
LLPS-Fus-1389Fusarium solani51.288e-98 308
LLPS-Sei-1075Setaria italica51.21e-44 164
LLPS-Map-0264Magnaporthe poae51.172e-90 289
LLPS-Gag-0905Gaeumannomyces graminis51.171e-92 295
LLPS-Pytr-1327Pyrenophora triticirepentis51.166e-88 285
LLPS-Lep-0439Leersia perrieri51.165e-46 167
LLPS-Pug-0828Puccinia graminis51.088e-99 312
LLPS-Mao-1125Magnaporthe oryzae51.011e-95 303
LLPS-Pyt-1378Pyrenophora teres51.05e-90 290
LLPS-Asni-0488Aspergillus niger50.872e-92 294
LLPS-Gas-0984Galdieria sulphuraria50.781e-44 167
LLPS-Zem-1083Zea mays50.02e-39 157
LLPS-Mua-1991Musa acuminata50.09e-47 167
LLPS-Arl-2364Arabidopsis lyrata50.06e-34 136
LLPS-Brr-0225Brassica rapa49.475e-43 167
LLPS-Bro-1018Brassica oleracea49.473e-43 168
LLPS-Brn-1172Brassica napus49.473e-43 168
LLPS-Crn-0847Cryptococcus neoformans49.141e-42 162
LLPS-Coc-0191Corchorus capsularis49.062e-33 135
LLPS-Pot-2138Populus trichocarpa48.977e-46 176
LLPS-Nia-1851Nicotiana attenuata48.73e-33 131
LLPS-Fuv-1038Fusarium verticillioides48.353e-95 302
LLPS-Met-1277Medicago truncatula47.833e-31 128
LLPS-Hov-1168Hordeum vulgare47.428e-42 164
LLPS-Ors-0185Oryza sativa46.861e-41 155
LLPS-Tra-1821Triticum aestivum46.633e-41 162
LLPS-Vir-1907Vigna radiata46.334e-32 130
LLPS-Gor-2385Gossypium raimondii46.243e-32 131
LLPS-Sot-1630Solanum tuberosum46.054e-32 125
LLPS-Phv-0196Phaseolus vulgaris45.71e-32 133
LLPS-Glm-1904Glycine max45.161e-31 130
LLPS-Org-1093Oryza glaberrima44.446e-31 128
LLPS-Orm-1070Oryza meridionalis44.445e-31 128
LLPS-Orgl-0617Oryza glumaepatula44.445e-31 128
LLPS-Cym-1073Cyanidioschyzon merolae43.792e-33 135
LLPS-Ast-1324Aspergillus terreus43.771e-66 226
LLPS-Via-1347Vigna angularis41.596e-32 130
LLPS-Ved-0342Verticillium dahliae36.441e-56 200