DrLLPS - Data resource of LLPS

LLPS-Fuv-1056
FVEG_10358

Integrated Annotations

▼ OVERVIEW


Status:	Unreviewed
Protein Name:	Acetyltransferase component of pyruvate dehydrogenase complex
Gene Name:	FVEG_10358
Ensembl Gene:	FVEG_10358
Ensembl Protein:	FVEG_10358T0
Organism:	Fusarium verticillioides
Taxa ID:	334819
LLPS Type:	LLPS regulator

▼ PROPERTY

——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:

Condensate	Evidence	Orthologs
Nucleolus, Stress granule, Others	Predicted from orthologs	(View)

Organism	DrLLPS ID	UniProt ID	LLPS type	Condensate	Identity	E-value	Score
Saccharomyces cerevisiae	LLPS-Sac-0020	P12695	Regulator	Stress granule	49.57	3e-123	375
Homo sapiens	LLPS-Hos-0703	P10515	Client	Nucleolus, Postsynaptic density	47.00	6e-22	103

▼ FUNCTION

The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

▼ CROSS REFERENCE

Database	Nucleotide ID	Protein ID
Ensembl	FVEG_10358T0	FVEG_10358T0
UniProt		W7MI00, W7MI00_GIBM7
GeneBank	DS022255	EWG51362.1, EWG51363.1
RefSeq	XM_018899483.1, XM_018899484.1	XP_018757553.1, XP_018757554.1

▼ SEQUENCE

Protein Sequence (FASTA)
1 MLSAALRRRV LAPTHSALRT GFAAHVVRHY ASFPEHQVIK MPALSPTMQA GNIGAWQKKP 60 61 GDSIAPGDVL VEIETDKAQM DFEFQEEGVI AKILKDAGEK DIAVGSPIAV LVEEGTDISA 120 121 FEKFSVEDAG GDAAKPAAPK KEEKSESKSE SASAPEPTPE PQQYQSQGRL QTALDRLPNI 180 181 SASAKRLARE KGISIDGLKG TGKNGQITEE DVKKASSTPA ASSAPSASYE DIPISGMRKT 240 241 IANRLVESTQ TNPHFYVTSS ISVSKLLKLR QALNSSADGK YKLSVNDFLI KAIAVASRKV 300 301 PQVNSSWRDG NIRQFNNVDV SVAVSTPTGL ITPIVTGVEG RGLEAISSQV KSLAKKARDG 360 361 KLKPEEYQGG TISISNMGMN PAVDHFTAVI NPPQAAILAV GTTKKVAIPA ENEAGVEFDD 420 421 QITLTASFDH KVVDGAVGAE WLKELKQVLE NPLELLL 457

Protein Sequence (FASTA)

1     MLSAALRRRV  LAPTHSALRT  GFAAHVVRHY  ASFPEHQVIK  MPALSPTMQA  GNIGAWQKKP  60
61    GDSIAPGDVL  VEIETDKAQM  DFEFQEEGVI  AKILKDAGEK  DIAVGSPIAV  LVEEGTDISA  120
121   FEKFSVEDAG  GDAAKPAAPK  KEEKSESKSE  SASAPEPTPE  PQQYQSQGRL  QTALDRLPNI  180
181   SASAKRLARE  KGISIDGLKG  TGKNGQITEE  DVKKASSTPA  ASSAPSASYE  DIPISGMRKT  240
241   IANRLVESTQ  TNPHFYVTSS  ISVSKLLKLR  QALNSSADGK  YKLSVNDFLI  KAIAVASRKV  300
301   PQVNSSWRDG  NIRQFNNVDV  SVAVSTPTGL  ITPIVTGVEG  RGLEAISSQV  KSLAKKARDG  360
361   KLKPEEYQGG  TISISNMGMN  PAVDHFTAVI  NPPQAAILAV  GTTKKVAIPA  ENEAGVEFDD  420
421   QITLTASFDH  KVVDGAVGAE  WLKELKQVLE  NPLELLL  457

▼ KEYWORD

ID	Family
KW-0012	Acyltransferase
KW-0181	Complete proteome
KW-0450	Lipoyl
KW-0670	Pyruvate
KW-1185	Reference proteome
KW-0808	Transferase

▼ GENE ONTOLOGY

ID	Classification	Description
GO:0005759	Cellular Component	Mitochondrial matrix
GO:0045254	Cellular Component	Pyruvate dehydrogenase complex
GO:0004742	Molecular Function	Dihydrolipoyllysine-residue acetyltransferase activity
GO:0006090	Biological Process	Pyruvate metabolic process

▼ KEGG

fvr:FVEG_10358

▼ ORTHOLOGY

DrLLPS ID	Organism	Identity	E-value	Score
LLPS-Fuo-0567	Fusarium oxysporum	98.91	0.0	822
LLPS-Fus-0693	Fusarium solani	85.25	0.0	742
LLPS-Trr-0662	Trichoderma reesei	79.52	0.0	601
LLPS-Trv-0872	Trichoderma virens	78.04	0.0	674
LLPS-Beb-1506	Beauveria bassiana	76.74	0.0	688
LLPS-Ved-1080	Verticillium dahliae	74.4	0.0	617
LLPS-Map-0219	Magnaporthe poae	73.87	0.0	597
LLPS-Cog-0978	Colletotrichum gloeosporioides	73.2	0.0	616
LLPS-Gag-0935	Gaeumannomyces graminis	72.35	0.0	609
LLPS-Cogr-0311	Colletotrichum graminicola	70.87	0.0	617
LLPS-Mao-0912	Magnaporthe oryzae	70.82	0.0	590
LLPS-Coo-1514	Colletotrichum orbiculare	69.44	0.0	605
LLPS-Yal-1441	Yarrowia lipolytica	69.05	4e-31	128
LLPS-Nec-0030	Neurospora crassa	66.96	0.0	594
LLPS-Asf-0598	Aspergillus flavus	66.67	0.0	567
LLPS-Aso-0283	Aspergillus oryzae	66.67	0.0	566
LLPS-Asc-1453	Aspergillus clavatus	65.91	0.0	559
LLPS-Asn-0165	Aspergillus nidulans	65.47	0.0	548
LLPS-Ast-0654	Aspergillus terreus	65.3	0.0	557
LLPS-Nef-0566	Neosartorya fischeri	65.23	0.0	562
LLPS-Asfu-0875	Aspergillus fumigatus	65.23	0.0	561
LLPS-Asni-0920	Aspergillus niger	65.07	0.0	554
LLPS-Blg-0419	Blumeria graminis	64.33	0.0	577
LLPS-Zyt-0252	Zymoseptoria tritici	63.82	8e-180	520
LLPS-Scs-0541	Sclerotinia sclerotiorum	63.19	0.0	561
LLPS-Pytr-0518	Pyrenophora triticirepentis	62.34	0.0	551
LLPS-Pyt-0382	Pyrenophora teres	62.13	0.0	551
LLPS-Phn-0985	Phaeosphaeria nodorum	61.02	2e-173	506
LLPS-Tum-1186	Tuber melanosporum	60.99	8e-165	478
LLPS-Vir-1343	Vigna radiata	60.24	3e-22	103
LLPS-Gor-0354	Gossypium raimondii	60.0	4e-28	121
LLPS-Thc-1523	Theobroma cacao	59.57	4e-26	115
LLPS-Dos-1234	Dothistroma septosporum	57.93	1e-164	480
LLPS-Mae-2430	Manihot esculenta	57.45	1e-24	110
LLPS-Sem-2379	Selaginella moellendorffii	56.79	5e-20	97.1
LLPS-Viv-0733	Vitis vinifera	56.07	4e-26	115
LLPS-Cym-0420	Cyanidioschyzon merolae	53.06	1e-24	110
LLPS-Brn-3032	Brassica napus	52.78	2e-21	100
LLPS-Bro-2496	Brassica oleracea	52.78	2e-21	100
LLPS-Kop-0446	Komagataella pastoris	52.44	6e-136	407
LLPS-Fia-0093	Ficedula albicollis	51.56	2e-87	284
LLPS-Tag-2532	Taeniopygia guttata	51.38	6e-87	284
LLPS-Scf-0599	Scleropages formosus	51.19	5e-18	90.5
LLPS-Pug-0558	Puccinia graminis	51.19	2e-82	269
LLPS-Sac-0020	Saccharomyces cerevisiae	49.79	1e-143	427
LLPS-Chr-0005	Chlamydomonas reinhardtii	49.11	3e-27	119
LLPS-Php-0757	Physcomitrella patens	49.02	4e-24	109
LLPS-Asm-0656	Astyanax mexicanus	48.96	1e-21	102
LLPS-Asg-0958	Ashbya gossypii	48.86	1e-138	413
LLPS-Ran-4342	Rattus norvegicus	48.0	3e-22	103
LLPS-Drm-1228	Drosophila melanogaster	47.92	4e-72	243
LLPS-Ere-0803	Erinaceus europaeus	47.83	1e-55	198
LLPS-Scc-0720	Schizosaccharomyces cryophilus	47.6	1e-132	399
LLPS-Scj-0922	Schizosaccharomyces japonicus	47.01	6e-127	384
LLPS-Gog-0338	Gorilla gorilla	47.0	5e-22	103
LLPS-Sus-2741	Sus scrofa	47.0	5e-22	103
LLPS-Hos-0703	Homo sapiens	47.0	4e-22	103
LLPS-Pat-2657	Pan troglodytes	47.0	4e-22	103
LLPS-Orl-0936	Oryzias latipes	46.94	7e-21	99.8
LLPS-Xet-0307	Xenopus tropicalis	46.85	6e-23	105
LLPS-Mel-0407	Melampsora laricipopulina	46.67	9e-111	342
LLPS-Spr-0639	Sporisorium reilianum	46.41	6e-107	333
LLPS-Abg-0102	Absidia glauca	46.15	3e-130	393
LLPS-Dio-2508	Dipodomys ordii	46.08	2e-21	101
LLPS-Fud-0003	Fukomys damarensis	46.0	1e-20	98.6
LLPS-Icp-3397	Ictalurus punctatus	46.0	3e-21	100
LLPS-Aon-2872	Aotus nancymaae	46.0	5e-21	100
LLPS-Aim-4260	Ailuropoda melanoleuca	46.0	5e-21	100
LLPS-Orc-4017	Oryctolagus cuniculus	46.0	9e-21	99.4
LLPS-Pap-3009	Pan paniscus	46.0	2e-20	98.2
LLPS-Urm-0368	Ursus maritimus	46.0	6e-21	99.8
LLPS-Fec-1097	Felis catus	46.0	6e-21	99.8
LLPS-Loa-1453	Loxodonta africana	46.0	6e-21	99.8
LLPS-Cas-1428	Carlito syrichta	46.0	8e-21	99.4
LLPS-Poa-0744	Pongo abelii	46.0	5e-21	100
LLPS-Scp-0790	Schizosaccharomyces pombe	45.93	2e-128	388
LLPS-Tar-0382	Takifugu rubripes	45.45	2e-20	98.2
LLPS-Orn-0575	Oreochromis niloticus	45.45	2e-113	355
LLPS-Gaga-0229	Gallus gallus	45.36	2e-20	98.2
LLPS-Mum-3507	Mus musculus	45.35	4e-112	351
LLPS-Myl-0448	Myotis lucifugus	45.27	2e-113	354
LLPS-Caj-2321	Callithrix jacchus	45.1	4e-21	100
LLPS-Maf-3073	Macaca fascicularis	45.1	5e-21	100
LLPS-Chs-3595	Chlorocebus sabaeus	45.1	5e-21	100
LLPS-Cea-0854	Cercocebus atys	45.1	5e-21	100
LLPS-Paa-0723	Papio anubis	45.1	5e-21	100
LLPS-Mal-2892	Mandrillus leucophaeus	45.1	5e-21	100
LLPS-Mup-2620	Mustela putorius furo	45.1	2e-21	101
LLPS-Otg-3730	Otolemur garnettii	45.1	7e-21	99.8
LLPS-Rhb-0569	Rhinopithecus bieti	45.1	5e-21	100
LLPS-Man-1865	Macaca nemestrina	45.1	5e-21	100
LLPS-Nol-1965	Nomascus leucogenys	45.1	3e-21	100
LLPS-Ict-2922	Ictidomys tridecemlineatus	45.1	1e-20	99.4
LLPS-Caf-2485	Canis familiaris	45.1	5e-21	100
LLPS-Cap-2228	Cavia porcellus	45.1	1e-20	98.6
LLPS-Mam-1987	Macaca mulatta	45.1	5e-21	100
LLPS-Meg-0233	Meleagris gallopavo	45.02	7e-113	350
LLPS-Ova-2176	Ovis aries	45.0	3e-21	100
LLPS-Tut-1457	Tursiops truncatus	45.0	2e-21	101
LLPS-Pes-1605	Pelodiscus sinensis	45.0	1e-13	77.0
LLPS-Mod-2792	Monodelphis domestica	45.0	2e-21	101
LLPS-Dac-0690	Daucus carota	44.9	1e-17	89.7
LLPS-Pof-3830	Poecilia formosa	44.87	1e-110	347
LLPS-Mea-3042	Mesocricetus auratus	44.83	1e-21	101
LLPS-Gas-0743	Galdieria sulphuraria	44.8	5e-117	360
LLPS-Lac-2360	Latimeria chalumnae	44.76	5e-21	100
LLPS-Ten-1120	Tetraodon nigroviridis	44.74	3e-112	351
LLPS-Eqc-4725	Equus caballus	44.44	1e-21	102
LLPS-Xim-0616	Xiphophorus maculatus	44.3	1e-110	347
LLPS-Orm-0462	Oryza meridionalis	44.21	1e-69	243
LLPS-Ora-0018	Ornithorhynchus anatinus	44.12	1e-113	352
LLPS-Via-2341	Vigna angularis	44.08	4e-101	316
LLPS-Bot-2105	Bos taurus	44.0	1e-20	99.0
LLPS-Scm-0387	Scophthalmus maximus	44.0	3e-20	97.8
LLPS-Miv-0579	Microbotryum violaceum	43.97	5e-106	330
LLPS-Anp-0143	Anas platyrhynchos	43.96	4e-17	88.2
LLPS-Cii-1673	Ciona intestinalis	43.93	4e-102	321
LLPS-Gaa-1406	Gasterosteus aculeatus	43.88	5e-110	345
LLPS-Anc-1891	Anolis carolinensis	43.85	1e-111	350
LLPS-Crn-0599	Cryptococcus neoformans	43.84	9e-116	355
LLPS-Sah-0056	Sarcophilus harrisii	43.82	1e-17	89.7
LLPS-Cis-1861	Ciona savignyi	43.37	2e-98	315
LLPS-Dar-2098	Danio rerio	43.33	5e-21	100
LLPS-Usm-0388	Ustilago maydis	43.25	3e-105	329
LLPS-Sei-1293	Setaria italica	43.12	9e-104	326
LLPS-Phv-1341	Phaseolus vulgaris	43.05	5e-106	332
LLPS-Sob-0329	Sorghum bicolor	42.89	2e-103	325
LLPS-Chc-0447	Chondrus crispus	42.86	1e-47	181
LLPS-Orbr-2326	Oryza brachyantha	42.82	1e-104	329
LLPS-Cae-0584	Caenorhabditis elegans	42.76	3e-106	332
LLPS-Hov-0064	Hordeum vulgare	42.73	2e-103	325
LLPS-Glm-2523	Glycine max	42.7	3e-105	330
LLPS-Met-1016	Medicago truncatula	42.63	5e-106	332
LLPS-Leo-1798	Lepisosteus oculatus	42.57	5e-106	335
LLPS-Tra-1361	Triticum aestivum	42.56	7e-103	324
LLPS-Tru-0561	Triticum urartu	42.56	1e-103	328
LLPS-Lep-0368	Leersia perrieri	42.49	6e-99	310
LLPS-Brr-1982	Brassica rapa	42.46	3e-105	330
LLPS-Coc-0405	Corchorus capsularis	42.46	5e-111	344
LLPS-Orb-0844	Oryza barthii	42.37	9e-104	326
LLPS-Orgl-1014	Oryza glumaepatula	42.37	7e-104	327
LLPS-Ors-1412	Oryza sativa	42.37	1e-103	326
LLPS-Org-2077	Oryza glaberrima	42.37	1e-103	326
LLPS-Orr-1463	Oryza rufipogon	42.37	9e-104	326
LLPS-Hea-0562	Helianthus annuus	42.29	4e-105	330
LLPS-Arl-2409	Arabidopsis lyrata	42.28	2e-103	325
LLPS-Orp-1625	Oryza punctata	42.14	2e-98	313
LLPS-Brd-1351	Brachypodium distachyon	42.07	6e-105	330
LLPS-Art-0957	Arabidopsis thaliana	42.06	2e-102	323
LLPS-Nia-0696	Nicotiana attenuata	42.01	2e-105	331
LLPS-Sot-0414	Solanum tuberosum	42.0	9e-107	334
LLPS-Sol-0120	Solanum lycopersicum	41.78	2e-106	333
LLPS-Mua-1294	Musa acuminata	41.7	9e-107	337
LLPS-Ori-2398	Oryza indica	41.61	1e-101	321
LLPS-Orni-1048	Oryza nivara	41.55	1e-101	321
LLPS-Pot-0493	Populus trichocarpa	41.43	8e-102	321
LLPS-Zem-2419	Zea mays	41.18	4e-102	324
LLPS-Cus-1013	Cucumis sativus	41.1	8e-103	324
LLPS-Amt-1575	Amborella trichopoda	40.49	2e-101	320
LLPS-Prp-1740	Prunus persica	39.61	3e-101	320
LLPS-Osl-1241	Ostreococcus lucimarinus	38.25	2e-89	285
LLPS-Put-0577	Puccinia triticina	38.06	2e-68	231

LLPS-Fuv-1056FVEG_10358

Protein Sequence

Nucleotide Sequence

LLPS-Fuv-1056
FVEG_10358