• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Fud-2325
H920_05180

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Sequestosome-1
Gene Name: H920_05180
Ensembl Gene: ENSFDAG00000006115.1
Ensembl Protein: ENSFDAP00000017567.1
Organism: Fukomys damarensis
Taxa ID: 885580
LLPS Type: Scaffold


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Droplet, Stress granule, OthersPredicted from orthologs(View)

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     LFIFLYWGLN  LGPCDWKIGT  VPLSYIPGHE  DGDLVAFSSD  EELMMAMSYV  KDDIFRIYIK  60
61    EKKEYRREHR  PQCVQGAPHP  MVHPNVICDG  CDGPVVGTRY  KCSVCPNYDL  CGVCEGKGIH  120
121   REHSKVPLAS  PLEHFAEGFA  HSRWFRKLKH  GHCRWPGWEM  GPPGNWSPRP  PRAGDARPSS  180
181   GAEPASGPSE  DPNVNFLKNV  GESVAAALSP  LGIEVDIDVE  HGGKRSRLTP  VSPESPSMED  240
241   KGSSQPSSCS  SEPSRPDSSG  KGMAQALAEQ  MRKIALEPTG  QPEEQMESDN  CSGGDEDWTH  300
301   LSSKEVDPST  GELQSLQMPE  SEGPSSLDPS  QQGPTGLKEA  ALYPHLPPEA  DPRLIESLSQ  360
361   MLSMGFSDEG  GWLTRLLQTK  NYDIGAALDT  IQYSKHPPPL  400
Nucleotide CDS Sequence (FASTA)
1     TTATTTATTT  TTTTGTATTG  GGGATTGAAC  TTAGGACCTT  GCGATTGGAA  GATAGGCACA  60
61    GTGCCACTGA  GCTACATACC  TGGCCATGAG  GACGGGGACT  TGGTGGCCTT  TTCCAGTGAC  120
121   GAGGAGCTGA  TGATGGCCAT  GTCCTATGTG  AAGGATGACA  TCTTCCGCAT  CTACATTAAA  180
181   GAGAAGAAAG  AGTACCGGAG  GGAGCACCGC  CCCCAGTGTG  TGCAGGGAGC  GCCTCACCCC  240
241   ATGGTGCACC  CCAACGTGAT  CTGTGACGGC  TGTGACGGGC  CTGTGGTGGG  AACCCGATAC  300
301   AAGTGCAGCG  TGTGCCCCAA  CTACGATCTG  TGTGGCGTCT  GCGAGGGGAA  AGGCATTCAC  360
361   AGGGAGCACA  GCAAGGTCCC  GCTGGCCAGC  CCCCTGGAGC  ACTTTGCTGA  GGGCTTCGCT  420
421   CACAGCCGCT  GGTTCCGGAA  GCTGAAACAC  GGGCATTGCC  GGTGGCCTGG  CTGGGAGATG  480
481   GGCCCGCCAG  GCAACTGGAG  CCCACGTCCT  CCTCGGGCGG  GGGATGCCCG  CCCCAGCTCC  540
541   GGTGCAGAAC  CAGCTTCTGG  CCCATCAGAG  GATCCCAATG  TAAATTTTCT  GAAGAATGTA  600
601   GGGGAGAGTG  TGGCGGCTGC  CCTCAGTCCT  CTGGGAATTG  AAGTTGACAT  TGACGTGGAG  660
661   CATGGAGGAA  AAAGGAGCCG  CCTGACACCC  GTCTCCCCGG  AGAGCCCCAG  CATGGAGGAC  720
721   AAGGGCAGCT  CCCAGCCGAG  CAGCTGCTCC  TCAGAGCCCA  GCAGGCCGGA  CAGCAGCGGC  780
781   AAGGGCATGG  CGCAGGCTCT  GGCAGAACAG  ATGAGGAAGA  TCGCCCTGGA  GCCCACGGGG  840
841   CAGCCCGAGG  AGCAGATGGA  GTCCGACAAC  TGTTCCGGAG  GAGATGAGGA  CTGGACTCAT  900
901   CTGTCTTCAA  AAGAAGTGGA  CCCCTCCACT  GGGGAGCTTC  AGTCCCTCCA  GATGCCAGAG  960
961   TCGGAAGGGC  CAAGCTCTCT  GGACCCTTCC  CAGCAGGGGC  CCACAGGGCT  GAAGGAGGCC  1020
1021  GCTTTGTACC  CGCACCTCCC  ACCAGAGGCT  GACCCCCGGC  TGATTGAGTC  ACTGTCCCAG  1080
1081  ATGCTGTCCA  TGGGCTTCTC  TGATGAAGGT  GGCTGGCTCA  CCCGGCTCCT  GCAGACCAAG  1140
1141  AACTACGACA  TAGGGGCCGC  CCTGGACACC  ATCCAGTACT  CGAAGCACCC  GCCACCGCTG  1200
1201  TGA  1203

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Ict-2485Ictidomys tridecemlineatus88.410.0 618
LLPS-Sus-0262Sus scrofa85.710.0 600
LLPS-Gog-3991Gorilla gorilla85.710.0 588
LLPS-Hos-0672Homo sapiens85.710.0 588
LLPS-Pap-0430Pan paniscus85.710.0 588
LLPS-Pat-2608Pan troglodytes85.710.0 588
LLPS-Fec-0271Felis catus85.710.0 590
LLPS-Nol-3695Nomascus leucogenys85.713e-91 280
LLPS-Rhb-3003Rhinopithecus bieti85.40.0 590
LLPS-Maf-4031Macaca fascicularis85.180.0 602
LLPS-Paa-1928Papio anubis85.180.0 602
LLPS-Man-0030Macaca nemestrina85.180.0 602
LLPS-Mum-0941Mus musculus84.990.0 604
LLPS-Mea-0041Mesocricetus auratus84.990.0 605
LLPS-Chs-1410Chlorocebus sabaeus84.910.0 602
LLPS-Cea-1763Cercocebus atys84.910.0 599
LLPS-Aon-2451Aotus nancymaae84.910.0 597
LLPS-Tut-0650Tursiops truncatus84.910.0 592
LLPS-Eqc-3816Equus caballus84.910.0 592
LLPS-Mam-2445Macaca mulatta84.910.0 596
LLPS-Aim-2558Ailuropoda melanoleuca84.780.0 583
LLPS-Mal-2359Mandrillus leucophaeus84.680.0 600
LLPS-Orc-3816Oryctolagus cuniculus84.220.0 595
LLPS-Mup-3046Mustela putorius furo83.780.0 572
LLPS-Otg-0737Otolemur garnettii83.160.0 577
LLPS-Ova-3742Ovis aries82.620.0 578
LLPS-Caj-1327Callithrix jacchus81.750.0 601
LLPS-Ere-0809Erinaceus europaeus81.550.0 562
LLPS-Myl-2005Myotis lucifugus81.020.0 573
LLPS-Urm-0891Ursus maritimus80.653e-95 297
LLPS-Ran-2979Rattus norvegicus80.550.0 596
LLPS-Cas-2819Carlito syrichta80.050.0 557
LLPS-Bot-2631Bos taurus79.440.0 531
LLPS-Caf-2270Canis familiaris78.765e-167 482
LLPS-Cap-2329Cavia porcellus72.397e-158 459
LLPS-Orn-3428Oreochromis niloticus66.671e-0860.8
LLPS-Abg-0091Absidia glauca64.712e-0757.4
LLPS-Mod-3492Monodelphis domestica61.663e-149 438
LLPS-Ora-2870Ornithorhynchus anatinus61.61e-142 421
LLPS-Anp-0656Anas platyrhynchos60.511e-134 399
LLPS-Meg-2136Meleagris gallopavo59.853e-145 426
LLPS-Gaga-0677Gallus gallus59.343e-143 422
LLPS-Fia-0811Ficedula albicollis59.095e-140 414
LLPS-Sah-1523Sarcophilus harrisii58.854e-136 402
LLPS-Tag-2188Taeniopygia guttata58.663e-135 399
LLPS-Xet-0929Xenopus tropicalis54.347e-129 386
LLPS-Tar-0889Takifugu rubripes49.848e-86 270
LLPS-Lac-0377Latimeria chalumnae49.492e-114 348
LLPS-Gaa-1551Gasterosteus aculeatus49.483e-103 319
LLPS-Ten-3550Tetraodon nigroviridis49.23e-101 314
LLPS-Gag-0912Gaeumannomyces graminis48.07e-0652.4
LLPS-Leo-2612Lepisosteus oculatus47.59e-116 352
LLPS-Cis-0668Ciona savignyi47.378e-0754.7
LLPS-Coo-0991Colletotrichum orbiculare47.062e-0654.3
LLPS-Pof-0371Poecilia formosa46.723e-106 328
LLPS-Cogr-1202Colletotrichum graminicola46.06e-0652.8
LLPS-Anc-2894Anolis carolinensis45.958e-98 305
LLPS-Cog-0445Colletotrichum gloeosporioides45.281e-0654.7
LLPS-Dar-1469Danio rerio45.274e-105 325
LLPS-Scf-2998Scleropages formosus45.112e-105 325
LLPS-Orl-1867Oryzias latipes44.944e-95 298
LLPS-Asm-1866Astyanax mexicanus44.722e-101 315
LLPS-Icp-3142Ictalurus punctatus44.682e-102 318
LLPS-Cae-0881Caenorhabditis elegans40.382e-0857.4
LLPS-Poa-2382Pongo abelii35.485e-0652.8