• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Ere-0790
DYNC1I2

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: cytoplasmic dynein 1 intermediate chain 2 isoform X1
Gene Name: DYNC1I2
Ensembl Gene: ENSEEUG00000001131.1
Ensembl Protein: ENSEEUP00000001018.1
Organism: Erinaceus europaeus
Taxa ID: 9365
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Centrosome/Spindle pole body, Postsynaptic density, OthersPredicted from orthologs(View)

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     TDQKKEAVAP  VQEESDLEKK  RREAEALLQS  MGLTPESPIA  DTCLFHYLVP  PPMSPSSKSV  60
61    STPSEAGSQD  SGDGAVGSRT  LHWDTDPSVL  QLHSDSDLGR  GPIKLGMAKI  TQVDFPPREI  120
121   VTYTKETQTP  VMAQPKEEEE  EEDDVVTPKP  PIEPEEEKTL  KKDEGNESKV  PPHELTEEEK  180
181   QQILHSEEFL  SFFDHSTRIV  ERALSEQINI  FFDYSGRDLE  DKEGEIQAGA  KLSLNRQFFD  240
241   ERWSKHRVVS  CLDWSSQYPE  LLVASYNNNE  DAPHEPDGVA  LVWNMKYKKT  TPEYVFHCQA  300
301   HPLFSGPSSQ  FWDRSNKRTP  VQRTPLSAAA  HTHPVYCVNV  VGTQNAHNLI  SISTDGKICS  360
361   WSLDMLSHPQ  DSMELVHKQS  KAVAVTSMSF  PVGDVNNFVV  GSEEGSVYTA  CRHGSKAGIS  420
421   EMFEGHQGPI  TGIHCHAAVG  AVDFSHLFVT  SSFDWTVKLW  TTKNNKPLYS  FEDNSDYVYD  480
481   VMWSPTHPAL  FACVDGMGRL  DLWNLNNDTE  VPTASISVEG  NPALNRVRWT  HSGREIAVGD  540
541   SEGQIVIFDV  GEQIAVPRND  EWARFGRTLA  EINANRADAE  EEAATRIPA  589
Nucleotide CDS Sequence (FASTA)
1     ACTGATCAGA  AGAAGGAAGC  AGTAGCTCCT  GTGCAAGAAG  AATCAGATCT  TGAAAAAAAA  60
61    AGAAGAGAAG  CCGAAGCACT  GCTTCAAAGC  ATGGGGCTGA  CTCCAGAATC  CCCCATTGCG  120
121   GATACCTGTC  TATTTCACTA  TTTAGTCCCT  CCTCCTATGT  CTCCATCCTC  CAAATCTGTG  180
181   AGCACGCCAA  GTGAAGCTGG  AAGCCAAGAC  TCTGGAGATG  GTGCAGTGGG  ATCTAGGACG  240
241   CTGCATTGGG  ATACAGATCC  ATCAGTTCTT  CAGCTTCACT  CAGATTCCGA  TTTGGGACGT  300
301   GGACCTATTA  AACTTGGAAT  GGCTAAAATT  ACACAAGTTG  ACTTTCCTCC  TCGAGAAATC  360
361   GTCACATATA  CAAAAGAAAC  TCAGACTCCA  GTTATGGCTC  AGCCTAAAGA  AGAGGAGGAG  420
421   GAAGAAGATG  ATGTGGTGAC  TCCTAAGCCA  CCTATTGAAC  CCGAAGAAGA  GAAAACTTTA  480
481   AAGAAAGATG  AGGGAAATGA  GAGTAAAGTC  CCTCCTCATG  AGCTAACTGA  AGAAGAAAAA  540
541   CAACAAATCT  TGCACTCTGA  GGAGTTTTTA  AGTTTCTTTG  ACCATTCTAC  AAGAATTGTA  600
601   GAAAGAGCGC  TTTCTGAGCA  GATTAATATC  TTCTTTGACT  ACAGTGGAAG  AGATTTGGAA  660
661   GACAAAGAGG  GAGAGATTCA  AGCAGGTGCT  AAACTGTCAT  TAAATCGGCA  ATTTTTCGAT  720
721   GAACGTTGGT  CAAAGCATCG  TGTTGTTAGC  TGTTTGGATT  GGTCATCTCA  GTATCCAGAG  780
781   TTACTTGTGG  CTTCCTATAA  TAACAACGAA  GATGCCCCTC  ATGAGCCTGA  TGGTGTGGCC  840
841   CTTGTATGGA  ACATGAAATA  CAAAAAAACT  ACTCCAGAGT  ATGTGTTTCA  CTGCCAGGCA  900
901   CATCCACTGT  TTAGTGGACC  ATCCAGCCAA  TTTTGGGATC  GTAGCAATAA  GAGAACTCCA  960
961   GTACAAAGAA  CCCCACTGTC  AGCGGCTGCA  CACACACATC  CTGTATATTG  TGTAAATGTC  1020
1021  GTTGGGACAC  AAAATGCTCA  CAATCTGATT  AGTATCTCTA  CTGATGGAAA  AATTTGTTCA  1080
1081  TGGAGTTTGG  ATATGCTTTC  CCATCCACAG  GATAGTATGG  AGTTGGTCCA  TAAACAGTCA  1140
1141  AAAGCAGTAG  CTGTGACATC  TATGTCCTTC  CCTGTTGGAG  ACGTCAACAA  CTTTGTTGTT  1200
1201  GGGAGTGAAG  AAGGTTCTGT  GTACACAGCA  TGCCGTCATG  GCAGCAAAGC  TGGAATCAGT  1260
1261  GAAATGTTTG  AGGGACATCA  AGGACCAATC  ACTGGCATCC  ATTGTCATGC  AGCTGTTGGA  1320
1321  GCGGTGGACT  TCTCACATCT  TTTTGTCACT  TCATCATTTG  ACTGGACAGT  GAAACTTTGG  1380
1381  ACAACTAAGA  ACAACAAGCC  TCTGTACTCA  TTTGAAGATA  ACTCAGACTA  TGTCTATGAT  1440
1441  GTTATGTGGT  CTCCCACTCA  CCCAGCCCTG  TTCGCCTGTG  TGGATGGCAT  GGGGAGGCTG  1500
1501  GACTTGTGGA  ATCTCAACAA  TGACACAGAG  GTACCAACAG  CCAGCATTTC  TGTGGAGGGT  1560
1561  AATCCTGCTC  TTAACCGTGT  AAGATGGACC  CATTCTGGAA  GAGAGATTGC  CGTGGGTGAT  1620
1621  TCTGAAGGAC  AGATTGTTAT  ATTTGATGTG  GGAGAGCAGA  TTGCTGTCCC  CCGAAATGAT  1680
1681  GAGTGGGCAC  GATTTGGACG  AACACTTGCA  GAAATTAATG  CAAATCGAGC  TGATGCCGAG  1740
1741  GAGGAAGCAG  CTACCCGGAT  ACCTGCTTAG  1770

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Cas-2876Carlito syrichta93.90.0 963
LLPS-Aim-2374Ailuropoda melanoleuca93.40.01030
LLPS-Mup-1045Mustela putorius furo93.390.01028
LLPS-Eqc-4342Equus caballus93.390.01029
LLPS-Fud-3841Fukomys damarensis93.220.01034
LLPS-Loa-4071Loxodonta africana93.220.01032
LLPS-Man-3894Macaca nemestrina93.220.01033
LLPS-Dio-3787Dipodomys ordii93.160.01018
LLPS-Cea-2192Cercocebus atys93.060.01032
LLPS-Maf-4543Macaca fascicularis93.060.01032
LLPS-Mal-3091Mandrillus leucophaeus93.060.01032
LLPS-Hos-0093Homo sapiens93.060.01032
LLPS-Ict-1342Ictidomys tridecemlineatus93.060.01031
LLPS-Poa-3757Pongo abelii93.060.01032
LLPS-Caj-4283Callithrix jacchus93.00.01049
LLPS-Gog-0654Gorilla gorilla93.00.01050
LLPS-Paa-4467Papio anubis93.00.01050
LLPS-Pat-2818Pan troglodytes93.00.01050
LLPS-Mam-1856Macaca mulatta93.00.01050
LLPS-Aon-1773Aotus nancymaae92.890.01030
LLPS-Tut-1793Tursiops truncatus92.890.01015
LLPS-Rhb-4557Rhinopithecus bieti92.890.01025
LLPS-Urm-0580Ursus maritimus92.890.01025
LLPS-Nol-2797Nomascus leucogenys92.890.01029
LLPS-Cap-4032Cavia porcellus92.730.01025
LLPS-Ova-3642Ovis aries92.230.01018
LLPS-Mum-3534Mus musculus92.070.01018
LLPS-Bot-3592Bos taurus91.90.0 973
LLPS-Myl-0003Myotis lucifugus91.750.01026
LLPS-Ran-2851Rattus norvegicus91.240.01013
LLPS-Chs-0414Chlorocebus sabaeus91.030.01010
LLPS-Ora-0184Ornithorhynchus anatinus90.080.0 996
LLPS-Otg-1866Otolemur garnettii89.920.0 975
LLPS-Caf-3087Canis familiaris89.590.0 972
LLPS-Fec-2957Felis catus89.420.0 966
LLPS-Tag-1584Taeniopygia guttata89.090.0 960
LLPS-Pap-0594Pan paniscus89.00.0 958
LLPS-Sus-4314Sus scrofa88.930.0 959
LLPS-Fia-0069Ficedula albicollis88.930.0 963
LLPS-Orc-3575Oryctolagus cuniculus88.610.0 942
LLPS-Sah-1444Sarcophilus harrisii88.60.0 962
LLPS-Mod-2673Monodelphis domestica88.180.01000
LLPS-Pes-0374Pelodiscus sinensis87.620.0 980
LLPS-Anp-0580Anas platyrhynchos87.620.0 966
LLPS-Meg-3253Meleagris gallopavo87.440.0 963
LLPS-Gaga-2204Gallus gallus84.790.0 917
LLPS-Anc-0423Anolis carolinensis84.630.0 912
LLPS-Lac-2897Latimeria chalumnae83.170.0 933
LLPS-Xet-3528Xenopus tropicalis82.380.0 920
LLPS-Leo-1652Lepisosteus oculatus78.460.0 862
LLPS-Tar-1474Takifugu rubripes77.740.0 863
LLPS-Scf-0546Scleropages formosus77.650.0 884
LLPS-Gaa-2954Gasterosteus aculeatus77.650.0 869
LLPS-Dar-2936Danio rerio77.090.0 871
LLPS-Scm-0597Scophthalmus maximus76.540.0 874
LLPS-Asm-2340Astyanax mexicanus76.490.0 873
LLPS-Xim-1356Xiphophorus maculatus75.220.0 846
LLPS-Orn-1018Oreochromis niloticus75.090.0 826
LLPS-Icp-0706Ictalurus punctatus75.00.0 870
LLPS-Ten-0577Tetraodon nigroviridis73.990.0 841
LLPS-Pof-3579Poecilia formosa73.650.0 805
LLPS-Mea-1925Mesocricetus auratus69.870.0 825
LLPS-Orl-2205Oryzias latipes69.670.0 798
LLPS-Cii-0197Ciona intestinalis52.250.0 534
LLPS-Drm-1374Drosophila melanogaster50.02e-180 528
LLPS-Abg-1522Absidia glauca45.24e-133 410
LLPS-Cis-0685Ciona savignyi45.071e-175 521
LLPS-Crn-0115Cryptococcus neoformans45.061e-115 367
LLPS-Cae-0172Caenorhabditis elegans42.082e-109 348
LLPS-Tum-0994Tuber melanosporum41.082e-104 336
LLPS-Spr-0776Sporisorium reilianum40.383e-104 337
LLPS-Trr-0747Trichoderma reesei40.133e-97 318
LLPS-Miv-0905Microbotryum violaceum40.092e-106 345
LLPS-Asni-1568Aspergillus niger39.963e-95 312
LLPS-Mel-1124Melampsora laricipopulina39.879e-101 322
LLPS-Trv-0727Trichoderma virens39.692e-96 316
LLPS-Put-0378Puccinia triticina39.566e-100 326
LLPS-Pug-0976Puccinia graminis39.341e-99 325
LLPS-Phn-1258Phaeosphaeria nodorum38.566e-95 312
LLPS-Ast-1283Aspergillus terreus38.531e-93 308
LLPS-Usm-0814Ustilago maydis38.514e-96 316
LLPS-Beb-0064Beauveria bassiana38.445e-93 307
LLPS-Scs-0408Sclerotinia sclerotiorum38.222e-98 322
LLPS-Asf-1532Aspergillus flavus38.28e-93 306
LLPS-Aso-1452Aspergillus oryzae38.28e-93 306
LLPS-Cogr-0802Colletotrichum graminicola37.953e-91 302
LLPS-Asc-0902Aspergillus clavatus37.931e-93 309
LLPS-Fuv-0596Fusarium verticillioides37.933e-95 313
LLPS-Nec-0872Neurospora crassa37.867e-98 320
LLPS-Coo-0435Colletotrichum orbiculare37.843e-92 305
LLPS-Asn-0117Aspergillus nidulans37.86e-92 304
LLPS-Nef-1455Neosartorya fischeri37.743e-92 305
LLPS-Asfu-0618Aspergillus fumigatus37.747e-93 307
LLPS-Fuo-0870Fusarium oxysporum37.723e-94 310
LLPS-Pytr-0202Pyrenophora triticirepentis37.692e-92 305
LLPS-Mao-0620Magnaporthe oryzae37.642e-92 305
LLPS-Blg-0915Blumeria graminis37.443e-93 307
LLPS-Pyt-0531Pyrenophora teres37.421e-95 314
LLPS-Fus-0881Fusarium solani37.344e-92 305
LLPS-Cog-0269Colletotrichum gloeosporioides37.167e-89 296
LLPS-Map-0959Magnaporthe poae37.142e-91 303
LLPS-Gag-0066Gaeumannomyces graminis37.063e-91 302
LLPS-Zyt-0339Zymoseptoria tritici36.495e-82 277
LLPS-Dos-1501Dothistroma septosporum36.157e-85 285
LLPS-Ved-0723Verticillium dahliae35.145e-33 131
LLPS-Yal-0171Yarrowia lipolytica34.211e-62 224
LLPS-Lem-1123Leptosphaeria maculans33.055e-74 256
LLPS-Orm-0543Oryza meridionalis30.856e-0653.5
LLPS-Orni-2354Oryza nivara29.792e-0655.1
LLPS-Tra-0445Triticum aestivum29.794e-0653.9
LLPS-Hov-1586Hordeum vulgare29.794e-0653.9
LLPS-Lep-1532Leersia perrieri29.793e-0654.3
LLPS-Orgl-2224Oryza glumaepatula29.792e-0655.1
LLPS-Orbr-1449Oryza brachyantha29.792e-0654.7
LLPS-Ors-2078Oryza sativa29.792e-0655.1
LLPS-Orr-2090Oryza rufipogon29.258e-0652.8
LLPS-Scp-0875Schizosaccharomyces pombe28.751e-38 153
LLPS-Sob-1132Sorghum bicolor28.726e-0653.1
LLPS-Zem-1149Zea mays28.725e-0653.5
LLPS-Nia-0566Nicotiana attenuata27.643e-0653.9
LLPS-Scc-1198Schizosaccharomyces cryophilus26.476e-33 137
LLPS-Sem-0637Selaginella moellendorffii24.93e-1580.9
LLPS-Scj-1187Schizosaccharomyces japonicus24.716e-24 110
LLPS-Kop-0776Komagataella pastoris23.684e-1892.0
LLPS-Chr-0489Chlamydomonas reinhardtii23.623e-1789.7