LLPS-Eqc-4333
PTK2B
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Protein tyrosine kinase 2 beta |
| Gene Name: | PTK2B |
| Ensembl Gene: | ENSECAG00000018924.2 |
| Ensembl Protein: | ENSECAP00000029476.1 |
| Organism: | Equus caballus |
| Taxa ID: | 9796 |
| LLPS Type: | Client |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Centrosome/Spindle pole body, Postsynaptic density | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSECAT00000036576.1 | ENSECAP00000029476.1 |
| Ensembl | ENSECAT00000064537.1 | ENSECAP00000039338.1 |
| Ensembl | ENSECAT00000021005.2 | ENSECAP00000017277.2 |
| Ensembl | ENSECAT00000031195.1 | ENSECAP00000033364.1 |
| Ensembl | ENSECAT00000037722.1 | ENSECAP00000023411.1 |
| Ensembl | ENSECAT00000057698.1 | ENSECAP00000035480.1 |
| UniProt | F7CGD4, F7CGD4_HORSE |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MSGVSEPLSR VKVGTLRRPE GPPEPMVVVP ADVEKEDVRI LKVCFYSNSF NPGKNFKLVK 60 61 CTVHTEIREV IASILLSGRI GPNIQLAECY GLRLKHMKSD EIHWLHPQMT VGEVQDKYEC 120 121 LHMEAEWRYD LQIRYLPEDF MESLKEDRTT LLYFYQQLRN DYMQRYASKV SEGMALQLGC 180 181 LELRRFFKDM PHNALDKKSN FELLEKEVGL DLFFPKQMQE NLKPKQFRKM IQQTFQQYAS 240 241 LREEECVMKF FNTLAGFANI DQETYRCELI QGWNITVDLV IGPKGIRQLT SQDTKPTCLA 300 301 EFKQIKSIRC LPLEEGQAVL QLGIEGAPQS LSIKTSSLAE AENMADLIDG YCRLQGEHKG 360 361 SLIIHPKKDG EKRNSLPQIP VLNLETQRSR LSESCSIESD IYAEIPDETL RRPGGPQYGI 420 421 AREDVVLSRI LGEGFFGEVY EGVYTNHKGE KINVAVKTCK KDCTLDNKEK FMSEAVIMKN 480 481 LDHPHIVKLI GIIEEEPTWI IMELYPFGEL GHYLERNKNS LKVLTLVLYS LQICKAMAYL 540 541 ESINCVHRDI AVRNILVASA NCVKLGDFGL SRYIEDEEYY KASVTRLPIK WMAPESINFR 600 601 RFTTASDVWM FAVCMWEILS FGKQPFFWLE NKDVIGVLEK GDRLPKPDLC PPILYTLMTR 660 661 CWDYDPSERP RFTELVCSLS DVYQMEKDID TEQERNARYR PPKILEPTAL QEPPPKPSRP 720 721 KYRTPPQTNL LAPTLQFQVP EGLCASSPTL TSPMEYPSPV NSLHTPPLHR HNVFKRHSMR 780 781 EGDFVRPSSR EEAQQLWEAE RVKMRQILDK QQKQMVEDYQ WLRQEEKSLD PMVYMNDKSP 840 841 LTPEKEPGYT EFTGPPQKPP RLGAQSIQPT ANLDRTDDLV YLNVMELVRA VLDLKNELCQ 900 901 LPPEGYVVVV KVRARGRRRG QQGAGCASRP GGKRGGAELP CLPSRCLSQE DPQYSKVLKG 960 961 NLVPGSLGRW VLSQKGSSQG KPEVLKRKVT VTLPLSLPER GPDPAEAHRE RGRSPALLAV 1020 1021 IFTDRGGCPR PRMCHWLSPL PFTSTCPSCV PHRRLMRALS SLILPAGPSA VGSDSTSERV 1080 1081 P 1081 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGTCTGGGG TGTCCGAGCC CCTGAGCCGA GTGAAGGTGG GCACGTTACG TCGGCCGGAG 60 61 GGCCCCCCGG AGCCCATGGT GGTGGTGCCA GCAGACGTGG AAAAGGAAGA CGTGCGGATC 120 121 CTCAAGGTCT GCTTCTATAG CAACAGCTTC AACCCCGGGA AGAACTTCAA GCTGGTGAAA 180 181 TGCACGGTGC ACACCGAGAT CCGGGAGGTC ATTGCCTCCA TCCTGCTGAG TGGGCGGATC 240 241 GGGCCCAACA TCCAGCTGGC TGAGTGCTAT GGGCTGAGGC TGAAGCACAT GAAGTCGGAT 300 301 GAGATCCACT GGCTGCACCC GCAGATGACG GTGGGTGAGG TGCAGGACAA GTATGAGTGT 360 361 CTACACATGG AAGCCGAGTG GAGGTATGAC CTTCAAATCC GCTACTTGCC CGAGGACTTC 420 421 ATGGAGAGCC TGAAAGAAGA TAGGACCACA CTGCTTTATT TTTACCAACA GCTCCGGAAT 480 481 GACTACATGC AGCGCTACGC CAGCAAGGTC AGCGAGGGCA TGGCCCTACA GCTGGGCTGC 540 541 CTGGAGCTCA GGAGGTTCTT CAAGGACATG CCCCACAATG CACTCGACAA AAAGTCCAAC 600 601 TTCGAGCTCC TAGAGAAGGA AGTGGGACTG GACCTGTTTT TCCCAAAGCA GATGCAAGAG 660 661 AACTTAAAGC CCAAGCAGTT CCGGAAGATG ATCCAGCAGA CGTTCCAGCA GTACGCCTCG 720 721 CTCAGGGAGG AGGAGTGCGT CATGAAGTTC TTCAACACCC TCGCGGGCTT TGCCAACATC 780 781 GACCAGGAGA CCTATCGCTG TGAACTCATT CAAGGTTGGA ACATTACTGT GGACCTGGTC 840 841 ATCGGCCCGA AAGGCATCCG CCAGCTGACA AGCCAAGATA CAAAGCCCAC CTGCCTGGCC 900 901 GAGTTCAAGC AGATCAAGTC CATCAGGTGC CTGCCCCTGG AGGAGGGCCA GGCGGTACTG 960 961 CAGTTGGGCA TTGAAGGCGC CCCCCAGTCC TTGTCCATCA AAACCTCCTC TCTGGCAGAG 1020 1021 GCTGAGAACA TGGCTGACCT CATAGACGGT TACTGCCGGC TGCAGGGGGA GCACAAAGGC 1080 1081 TCTCTCATCA TTCATCCCAA GAAAGATGGT GAGAAGCGGA ACAGCCTGCC CCAGATCCCG 1140 1141 GTGCTGAACC TGGAGACTCA GCGGTCCCGC CTCTCAGAAA GCTGTAGCAT AGAATCAGAC 1200 1201 ATCTATGCAG AGATTCCCGA CGAGACCCTG CGAAGGCCAG GAGGCCCACA GTATGGCATC 1260 1261 GCCCGGGAAG ATGTGGTTCT GAGTCGCATT CTTGGTGAAG GCTTTTTTGG GGAGGTCTAC 1320 1321 GAAGGTGTCT ACACAAATCA CAAAGGGGAG AAAATCAATG TGGCTGTGAA GACCTGCAAG 1380 1381 AAGGACTGTA CTCTCGACAA CAAGGAGAAG TTCATGAGTG AGGCAGTGAT CATGAAGAAC 1440 1441 CTCGACCACC CGCACATTGT GAAGCTCATC GGCATCATCG AAGAGGAGCC CACCTGGATC 1500 1501 ATCATGGAAC TGTATCCCTT CGGGGAGCTG GGCCACTACC TGGAGCGGAA CAAGAACTCC 1560 1561 CTGAAGGTAC TCACTCTCGT CCTGTACTCG CTGCAGATTT GCAAGGCCAT GGCCTACCTG 1620 1621 GAGAGCATCA ACTGTGTGCA CAGGGACATC GCCGTCCGAA ATATCCTGGT GGCCTCTGCT 1680 1681 AACTGTGTGA AGCTGGGGGA CTTTGGCCTC TCCCGATACA TTGAGGACGA GGAGTATTAC 1740 1741 AAAGCCTCTG TGACTCGGCT CCCCATCAAA TGGATGGCCC CCGAGTCCAT TAACTTCCGC 1800 1801 CGCTTCACGA CGGCCAGCGA CGTCTGGATG TTTGCCGTGT GCATGTGGGA GATCCTGAGC 1860 1861 TTTGGGAAGC AGCCCTTCTT CTGGCTGGAG AACAAGGATG TCATCGGGGT GCTGGAGAAG 1920 1921 GGGGACCGGC TGCCCAAGCC CGACCTCTGC CCGCCTATTC TCTACACCCT CATGACCCGC 1980 1981 TGCTGGGACT ACGACCCCAG CGAGCGGCCC CGCTTTACCG AGCTCGTGTG CAGCCTCAGT 2040 2041 GACGTTTATC AGATGGAGAA AGACATCGAC ACAGAGCAGG AGAGGAATGC TCGCTATCGA 2100 2101 CCTCCCAAAA TCTTGGAGCC CACAGCCCTC CAGGAGCCCC CACCCAAGCC CAGCCGCCCC 2160 2161 AAGTACAGAA CCCCTCCACA AACCAACCTT CTGGCTCCCA CACTGCAGTT CCAGGTCCCC 2220 2221 GAGGGTCTGT GTGCCAGCTC ACCTACGCTC ACCAGCCCTA TGGAGTACCC ATCTCCTGTA 2280 2281 AACTCGCTGC ACACCCCGCC TCTCCACCGG CACAATGTCT TCAAGCGCCA CAGCATGCGG 2340 2341 GAGGGGGACT TCGTCCGACC CAGCAGCCGA GAAGAGGCCC AGCAGCTCTG GGAGGCCGAG 2400 2401 AGGGTCAAGA TGCGGCAGAT CCTGGATAAG CAGCAGAAGC AGATGGTGGA AGATTACCAG 2460 2461 TGGCTGAGGC AGGAGGAGAA ATCCTTGGAC CCCATGGTTT ACATGAACGA TAAGTCCCCG 2520 2521 TTGACCCCGG AGAAGGAGCC TGGCTACACA GAGTTCACGG GACCCCCACA GAAGCCACCG 2580 2581 CGGCTGGGCG CTCAGTCCAT CCAGCCCACA GCCAACCTGG ACCGCACCGA CGACCTGGTG 2640 2641 TACCTCAACG TCATGGAGCT GGTGCGGGCT GTGCTGGACC TCAAGAACGA GCTCTGTCAG 2700 2701 CTGCCTCCCG AGGGCTACGT GGTGGTGGTG AAGAACGTGG GCCTGACCCT GCGGAAGCTC 2760 2761 ATCGGGAGCG TGGACGATCT CCTGCCCTCC TTGCCGTCAT CTTCACGGAC CGAGATTGAG 2820 2821 GGGACCCAGA AACTGCTCAA CAAGGACCTG GCTGAGCTCA TCAATAAGAT GCGGCTGGCC 2880 2881 CAGCAAAATG CCGTGACCTC CCTGAGCGAG GAGTGCAAGC GACAGATGCT CACAGCCTCC 2940 2941 CACACCCTGG CTGTGGACGC CAAGAACCTG CTCGATGCTG TGGACCAGGC CAAGGTTCTG 3000 3001 GCCAACCTGG CCCACCCGCC TGCAGAGTGA 3030 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Urm-2849 | Ursus maritimus | 96.35 | 0.0 | 1752 |
| LLPS-Sus-0667 | Sus scrofa | 96.24 | 0.0 | 1748 |
| LLPS-Mup-1753 | Mustela putorius furo | 96.13 | 0.0 | 1749 |
| LLPS-Caf-2774 | Canis familiaris | 96.13 | 0.0 | 1761 |
| LLPS-Aim-4076 | Ailuropoda melanoleuca | 95.92 | 0.0 | 1747 |
| LLPS-Gog-0878 | Gorilla gorilla | 95.8 | 0.0 | 1750 |
| LLPS-Pap-1812 | Pan paniscus | 95.8 | 0.0 | 1749 |
| LLPS-Pat-2458 | Pan troglodytes | 95.8 | 0.0 | 1746 |
| LLPS-Hos-0751 | Homo sapiens | 95.8 | 0.0 | 1749 |
| LLPS-Maf-3582 | Macaca fascicularis | 95.46 | 0.0 | 1748 |
| LLPS-Aon-4683 | Aotus nancymaae | 95.46 | 0.0 | 1744 |
| LLPS-Paa-3093 | Papio anubis | 95.46 | 0.0 | 1746 |
| LLPS-Mal-2351 | Mandrillus leucophaeus | 95.46 | 0.0 | 1744 |
| LLPS-Bot-1385 | Bos taurus | 95.46 | 0.0 | 1732 |
| LLPS-Man-2366 | Macaca nemestrina | 95.46 | 0.0 | 1748 |
| LLPS-Cas-0550 | Carlito syrichta | 95.46 | 0.0 | 1736 |
| LLPS-Poa-2789 | Pongo abelii | 95.46 | 0.0 | 1747 |
| LLPS-Mam-1804 | Macaca mulatta | 95.46 | 0.0 | 1750 |
| LLPS-Chs-0094 | Chlorocebus sabaeus | 95.35 | 0.0 | 1744 |
| LLPS-Cea-2076 | Cercocebus atys | 95.35 | 0.0 | 1744 |
| LLPS-Caj-2885 | Callithrix jacchus | 95.13 | 0.0 | 1738 |
| LLPS-Rhb-2598 | Rhinopithecus bieti | 95.13 | 0.0 | 1740 |
| LLPS-Ova-4210 | Ovis aries | 95.02 | 0.0 | 1732 |
| LLPS-Orc-0034 | Oryctolagus cuniculus | 94.69 | 0.0 | 1710 |
| LLPS-Dio-3407 | Dipodomys ordii | 94.47 | 0.0 | 1729 |
| LLPS-Ran-2236 | Rattus norvegicus | 94.25 | 0.0 | 1717 |
| LLPS-Mea-3459 | Mesocricetus auratus | 94.14 | 0.0 | 1712 |
| LLPS-Mum-3214 | Mus musculus | 94.14 | 0.0 | 1713 |
| LLPS-Myl-2891 | Myotis lucifugus | 94.03 | 0.0 | 1714 |
| LLPS-Fec-4385 | Felis catus | 93.85 | 0.0 | 1735 |
| LLPS-Loa-4407 | Loxodonta africana | 93.82 | 0.0 | 1687 |
| LLPS-Cap-2391 | Cavia porcellus | 93.81 | 0.0 | 1709 |
| LLPS-Fud-0552 | Fukomys damarensis | 93.69 | 0.0 | 1712 |
| LLPS-Otg-4714 | Otolemur garnettii | 92.97 | 0.0 | 1691 |
| LLPS-Sah-2730 | Sarcophilus harrisii | 91.07 | 0.0 | 1673 |
| LLPS-Mod-3640 | Monodelphis domestica | 89.4 | 0.0 | 1621 |
| LLPS-Ora-1482 | Ornithorhynchus anatinus | 82.27 | 0.0 | 1194 |
| LLPS-Pes-1890 | Pelodiscus sinensis | 81.52 | 0.0 | 1512 |
| LLPS-Nol-4042 | Nomascus leucogenys | 81.23 | 0.0 | 1315 |
| LLPS-Ict-4058 | Ictidomys tridecemlineatus | 81.19 | 0.0 | 1381 |
| LLPS-Gaga-1437 | Gallus gallus | 76.07 | 0.0 | 1376 |
| LLPS-Fia-3570 | Ficedula albicollis | 74.74 | 0.0 | 1305 |
| LLPS-Meg-1705 | Meleagris gallopavo | 70.03 | 0.0 | 1228 |
| LLPS-Xet-1286 | Xenopus tropicalis | 68.23 | 0.0 | 1011 |
| LLPS-Leo-2496 | Lepisosteus oculatus | 64.1 | 0.0 | 1113 |
| LLPS-Asm-3319 | Astyanax mexicanus | 61.65 | 0.0 | 1035 |
| LLPS-Pof-2091 | Poecilia formosa | 61.4 | 0.0 | 1033 |
| LLPS-Icp-0043 | Ictalurus punctatus | 61.17 | 0.0 | 1016 |
| LLPS-Scf-1800 | Scleropages formosus | 60.78 | 0.0 | 1021 |
| LLPS-Orn-3176 | Oreochromis niloticus | 60.67 | 0.0 | 1028 |
| LLPS-Gaa-1234 | Gasterosteus aculeatus | 60.62 | 0.0 | 1025 |
| LLPS-Orl-0315 | Oryzias latipes | 60.36 | 0.0 | 1004 |
| LLPS-Xim-3193 | Xiphophorus maculatus | 60.21 | 0.0 | 1019 |
| LLPS-Tar-0183 | Takifugu rubripes | 59.7 | 0.0 | 1004 |
| LLPS-Scm-2414 | Scophthalmus maximus | 59.61 | 0.0 | 991 |
| LLPS-Dar-0964 | Danio rerio | 58.92 | 0.0 | 1003 |
| LLPS-Ten-1393 | Tetraodon nigroviridis | 58.38 | 0.0 | 994 |
| LLPS-Lac-0581 | Latimeria chalumnae | 55.33 | 0.0 | 764 |
| LLPS-Tag-3123 | Taeniopygia guttata | 46.15 | 8e-63 | 234 |
| LLPS-Anc-2144 | Anolis carolinensis | 45.69 | 9e-62 | 231 |
| LLPS-Cii-1598 | Ciona intestinalis | 43.64 | 2e-55 | 211 |
| LLPS-Anp-1782 | Anas platyrhynchos | 42.61 | 3e-56 | 214 |
| LLPS-Drm-1666 | Drosophila melanogaster | 41.63 | 2e-51 | 203 |