LLPS-Caf-2774
PTK2B
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Protein tyrosine kinase 2 beta |
| Gene Name: | PTK2B |
| Ensembl Gene: | ENSCAFG00000008670.3 |
| Ensembl Protein: | ENSCAFP00000012751.3 |
| Organism: | Canis familiaris |
| Taxa ID: | 9615 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Centrosome/Spindle pole body, Postsynaptic density | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSCAFT00000013788.3 | ENSCAFP00000012751.3 |
| UniProt | E2QTG4, E2QTG4_CANLF | |
| GeneBank | AAEX03014346 | |
| RefSeq | XM_005635677.2, XM_005635678.2, XM_014107549.1 | XP_005635734.1, XP_005635735.1, XP_013963024.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MSGVSEPLSR VKVGTLRHPQ GPPESMVVVP VDVEKEDVRI LKVCFYSNSF NPGKNFKLVK 60 61 CTVHTEIQEV IASILLSGRI GPNIQLAECY GLRLKHMKSD EIHWLHPQMT VGEVQDKYEC 120 121 LHVEAEWRYD LQIRYLPEDF MESLKEDRTT LLYFYQQLRN DYMQRYASKV SEGMALQLGC 180 181 LELRRFFKDM PHNALDKKSN FELLEKEVGL DLFFPKQMQE NLKPKQFRKM IQQTFQQYAS 240 241 LREEECVMKF FNTLAGFANI DQETYRCELI QGWNITVDLV IGPKGIRQLT SQDAKPTCLA 300 301 EFKQIKSIRC LPLEEGQAIL QLGIEGAPQS LSIKTSSLAE AENMADLVDG YCRLQGEHKG 360 361 SLIIHPKKDG EKRNSLPQIP MLNLEAQRPH LSESCSIESD IYAEIPDETL RRPGGPQYGV 420 421 TREDVVLNRI LGEGFFGEVY EGVYTNHKGE KINVAVKTCK KDCTLDNKEK FLSEAVIMKN 480 481 LDHPHIVKLI GIIEEEPTWI IMELYPYGEL GHYLERNKNS LKVLTLVLYS LQICKAMAYL 540 541 ENINCVHRDI AVRNILVAST ECVKLGDFGL SRYIEDEEYY KASVTRLPIK WMSPESINFR 600 601 RFTTASDVWM FAVCMWEILS FGKQPFFWLE NKDVIGVLEK GDRLPKPDLC PPVLYTLMTR 660 661 CWDYDPSERP RFTELVCNLS DIYQMEKDIA IEQERNARYR PPKILEPTAY QEPPPKPSRP 720 721 KYRLPPQTNL LAPKLQFQVP EGLCASSPTL TSPMEYPSPV NSLHTPPLHR HNVFKRHSMR 780 781 EEDFIRPSSR EEAQQLWEAE RLKMRQILDK QQKQMVEDYQ WLRQEEKSLD PMLYMNDKSP 840 841 LTPEKEAGYT EFTGPPQKPP RLGAQSIQPT ANLDRTDDLV YLNVMELVRA VLDLKNELCQ 900 901 LPPEGYVVVV KNVGLTLRKL IGSVDDLLPS LPSSSRTEIE GTQKLLNKDL AELINKMRLA 960 961 QQNAVTSLSE ECKRQMLTAS HTLAVDAKNL LDAVDQAKVL ANLAHPPAE 1009 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGTCTGGGG TGTCCGAGCC CCTGAGCCGA GTGAAGGTGG GCACCTTACG TCATCCCCAA 60 61 GGCCCCCCAG AGTCCATGGT GGTGGTGCCA GTAGATGTGG AGAAGGAAGA CGTGCGGATC 120 121 CTCAAGGTCT GCTTCTATAG CAACAGCTTC AACCCTGGGA AGAACTTTAA GCTGGTTAAA 180 181 TGCACTGTGC ACACCGAGAT CCAGGAGGTC ATTGCCTCCA TCCTGCTGAG CGGACGGATC 240 241 GGGCCCAACA TCCAGCTGGC TGAGTGCTAT GGGCTGAGGC TGAAGCACAT GAAGTCGGAT 300 301 GAGATCCATT GGTTGCACCC GCAGATGACA GTGGGTGAGG TGCAGGACAA GTACGAGTGT 360 361 CTGCATGTGG AAGCCGAGTG GAGGTATGAT CTTCAAATCC GCTACTTGCC AGAGGACTTC 420 421 ATGGAAAGCC TAAAAGAAGA CAGGACAACG CTACTGTATT TTTACCAACA GCTACGGAAT 480 481 GACTACATGC AACGCTATGC CAGCAAGGTC AGCGAGGGCA TGGCCCTGCA GCTAGGCTGT 540 541 CTGGAGCTCA GGCGGTTCTT CAAGGACATG CCTCACAATG CACTTGACAA AAAGTCCAAC 600 601 TTTGAGCTCC TGGAGAAGGA AGTGGGACTG GACCTATTTT TCCCAAAGCA GATGCAGGAG 660 661 AACTTAAAGC CCAAGCAGTT CCGGAAGATG ATCCAGCAGA CGTTCCAGCA GTATGCGTCG 720 721 CTCAGGGAGG AGGAGTGCGT CATGAAGTTC TTCAACACCC TCGCAGGCTT TGCCAACATC 780 781 GACCAGGAGA CCTATCGCTG TGAACTCATT CAAGGATGGA ACATTACTGT GGACCTAGTC 840 841 ATCGGCCCTA AGGGCATCCG CCAGCTGACA AGTCAAGATG CAAAGCCCAC CTGCCTGGCC 900 901 GAATTCAAGC AGATCAAGTC CATCAGGTGC CTCCCTCTGG AGGAGGGCCA GGCAATACTG 960 961 CAGCTGGGTA TTGAAGGCGC CCCCCAGTCC TTGTCCATCA AAACCTCCTC TCTGGCAGAG 1020 1021 GCCGAGAACA TGGCTGACCT GGTGGACGGT TACTGCCGGC TGCAGGGGGA GCACAAAGGC 1080 1081 TCTCTCATCA TTCATCCCAA GAAAGATGGT GAGAAGCGGA ACAGCCTGCC CCAGATCCCC 1140 1141 ATGCTAAACC TGGAGGCGCA GCGGCCCCAC CTGTCAGAGA GCTGCAGCAT AGAATCAGAC 1200 1201 ATCTATGCAG AGATTCCCGA TGAGACCCTT CGAAGGCCTG GAGGCCCGCA GTATGGTGTC 1260 1261 ACACGGGAAG ATGTGGTCCT GAATCGGATT CTTGGTGAAG GCTTTTTTGG GGAGGTCTAT 1320 1321 GAAGGTGTCT ACACAAATCA CAAAGGGGAG AAAATCAATG TAGCTGTAAA GACCTGCAAG 1380 1381 AAGGACTGCA CTCTGGACAA CAAGGAGAAG TTCCTGAGTG AGGCAGTGAT CATGAAGAAT 1440 1441 CTCGACCACC CGCATATTGT GAAACTGATC GGCATCATTG AAGAGGAGCC CACCTGGATC 1500 1501 ATCATGGAAT TGTATCCCTA CGGTGAGCTG GGCCACTACC TGGAGAGGAA CAAGAACTCC 1560 1561 CTGAAGGTGC TCACCCTCGT CCTGTACTCA TTGCAGATTT GCAAGGCCAT GGCCTACCTG 1620 1621 GAGAACATCA ACTGTGTCCA CAGGGACATC GCCGTCCGAA ACATCCTGGT GGCCTCCACT 1680 1681 GAGTGTGTGA AGCTGGGCGA CTTTGGCCTT TCCCGGTACA TTGAGGATGA GGAGTACTAC 1740 1741 AAAGCCTCTG TGACTCGTCT TCCCATCAAG TGGATGTCCC CTGAGTCCAT CAACTTCCGC 1800 1801 CGCTTTACGA CAGCCAGTGA TGTCTGGATG TTCGCTGTAT GCATGTGGGA GATCCTGAGC 1860 1861 TTTGGCAAGC AACCCTTCTT CTGGCTGGAG AACAAGGATG TCATTGGGGT GCTCGAGAAA 1920 1921 GGGGACCGGC TGCCCAAGCC CGACCTCTGC CCACCTGTTC TCTACACCCT TATGACTCGC 1980 1981 TGCTGGGACT ACGACCCCAG TGAGAGGCCA CGCTTCACTG AGCTCGTGTG CAACCTCAGT 2040 2041 GACATTTATC AGATGGAGAA GGACATTGCT ATAGAGCAGG AGAGGAATGC TCGCTACCGA 2100 2101 CCTCCCAAAA TCTTGGAGCC CACAGCCTAC CAGGAACCCC CACCTAAGCC CAGCCGGCCT 2160 2161 AAGTACAGAC TCCCTCCACA AACCAACCTC TTGGCTCCCA AGCTACAGTT CCAGGTCCCT 2220 2221 GAGGGTCTGT GTGCCAGCTC ACCTACGCTC ACCAGCCCTA TGGAGTATCC ATCTCCTGTA 2280 2281 AACTCGCTGC ATACCCCACC TCTCCACCGG CACAATGTCT TCAAGCGCCA CAGCATGCGG 2340 2341 GAGGAGGACT TCATCCGACC CAGCAGCCGA GAAGAAGCTC AGCAGCTATG GGAGGCCGAG 2400 2401 AGGCTCAAGA TGAGACAGAT CCTGGACAAG CAGCAGAAGC AGATGGTGGA AGATTACCAG 2460 2461 TGGCTGAGGC AGGAGGAGAA ATCCTTGGAC CCCATGTTGT ACATGAACGA TAAGTCCCCA 2520 2521 CTGACCCCAG AGAAGGAGGC TGGCTACACG GAGTTCACGG GTCCCCCACA GAAGCCACCA 2580 2581 CGGCTGGGCG CGCAGTCCAT CCAGCCCACA GCCAACCTGG ACCGGACCGA TGACCTGGTG 2640 2641 TACCTCAATG TCATGGAGCT AGTGCGGGCT GTGTTGGATC TCAAGAATGA GCTCTGCCAG 2700 2701 CTGCCTCCTG AAGGCTACGT GGTGGTGGTG AAGAACGTGG GCCTGACCCT GCGGAAGCTC 2760 2761 ATTGGGAGTG TGGATGATCT CCTGCCCTCC TTGCCGTCAT CCTCTCGGAC AGAGATTGAG 2820 2821 GGGACCCAGA AACTGCTCAA CAAGGATCTA GCAGAGCTCA TCAATAAGAT GCGCCTCGCC 2880 2881 CAGCAAAATG CCGTGACCTC CCTGAGCGAG GAGTGCAAGC GGCAGATGCT CACAGCCTCC 2940 2941 CACACCCTGG CCGTGGACGC CAAAAACCTG CTCGATGCCG TAGACCAGGC CAAAGTTCTG 3000 3001 GCCAATCTGG CCCACCCGCC TGCAGAGTGA 3030 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Urm-2849 | Ursus maritimus | 98.61 | 0.0 | 1973 |
| LLPS-Mup-1753 | Mustela putorius furo | 98.41 | 0.0 | 1974 |
| LLPS-Aim-4076 | Ailuropoda melanoleuca | 98.02 | 0.0 | 1967 |
| LLPS-Sus-0667 | Sus scrofa | 97.13 | 0.0 | 1949 |
| LLPS-Gog-0878 | Gorilla gorilla | 96.43 | 0.0 | 1942 |
| LLPS-Pat-2458 | Pan troglodytes | 96.23 | 0.0 | 1935 |
| LLPS-Pap-1812 | Pan paniscus | 96.23 | 0.0 | 1939 |
| LLPS-Hos-0751 | Homo sapiens | 96.23 | 0.0 | 1940 |
| LLPS-Mal-2351 | Mandrillus leucophaeus | 96.23 | 0.0 | 1939 |
| LLPS-Mam-1804 | Macaca mulatta | 96.2 | 0.0 | 1922 |
| LLPS-Man-2366 | Macaca nemestrina | 96.2 | 0.0 | 1921 |
| LLPS-Maf-3582 | Macaca fascicularis | 96.2 | 0.0 | 1921 |
| LLPS-Eqc-4333 | Equus caballus | 96.14 | 0.0 | 1756 |
| LLPS-Bot-1385 | Bos taurus | 96.13 | 0.0 | 1928 |
| LLPS-Fec-4385 | Felis catus | 96.12 | 0.0 | 1954 |
| LLPS-Paa-3093 | Papio anubis | 96.1 | 0.0 | 1916 |
| LLPS-Chs-0094 | Chlorocebus sabaeus | 96.0 | 0.0 | 1914 |
| LLPS-Cea-2076 | Cercocebus atys | 96.0 | 0.0 | 1914 |
| LLPS-Poa-2789 | Pongo abelii | 95.94 | 0.0 | 1938 |
| LLPS-Ova-4210 | Ovis aries | 95.94 | 0.0 | 1922 |
| LLPS-Aon-4683 | Aotus nancymaae | 95.94 | 0.0 | 1935 |
| LLPS-Cas-0550 | Carlito syrichta | 95.84 | 0.0 | 1931 |
| LLPS-Caj-2885 | Callithrix jacchus | 95.84 | 0.0 | 1931 |
| LLPS-Rhb-2598 | Rhinopithecus bieti | 95.74 | 0.0 | 1932 |
| LLPS-Cap-2391 | Cavia porcellus | 95.24 | 0.0 | 1913 |
| LLPS-Dio-3407 | Dipodomys ordii | 95.24 | 0.0 | 1917 |
| LLPS-Orc-0034 | Oryctolagus cuniculus | 95.14 | 0.0 | 1906 |
| LLPS-Loa-4407 | Loxodonta africana | 95.05 | 0.0 | 1882 |
| LLPS-Mea-3459 | Mesocricetus auratus | 95.04 | 0.0 | 1907 |
| LLPS-Ran-2236 | Rattus norvegicus | 94.95 | 0.0 | 1910 |
| LLPS-Fud-0552 | Fukomys damarensis | 94.95 | 0.0 | 1909 |
| LLPS-Mum-3214 | Mus musculus | 94.75 | 0.0 | 1906 |
| LLPS-Otg-4714 | Otolemur garnettii | 93.89 | 0.0 | 1889 |
| LLPS-Myl-2891 | Myotis lucifugus | 93.86 | 0.0 | 1892 |
| LLPS-Sah-2730 | Sarcophilus harrisii | 92.0 | 0.0 | 1860 |
| LLPS-Mod-3640 | Monodelphis domestica | 90.21 | 0.0 | 1805 |
| LLPS-Nol-4042 | Nomascus leucogenys | 83.87 | 0.0 | 1518 |
| LLPS-Ict-4058 | Ictidomys tridecemlineatus | 83.37 | 0.0 | 1582 |
| LLPS-Ora-1482 | Ornithorhynchus anatinus | 82.69 | 0.0 | 1246 |
| LLPS-Pes-1890 | Pelodiscus sinensis | 82.06 | 0.0 | 1674 |
| LLPS-Gaga-1437 | Gallus gallus | 78.02 | 0.0 | 1540 |
| LLPS-Fia-3570 | Ficedula albicollis | 76.1 | 0.0 | 1462 |
| LLPS-Meg-1705 | Meleagris gallopavo | 72.43 | 0.0 | 1392 |
| LLPS-Xet-1286 | Xenopus tropicalis | 70.4 | 0.0 | 1176 |
| LLPS-Leo-2496 | Lepisosteus oculatus | 64.92 | 0.0 | 1250 |
| LLPS-Icp-0043 | Ictalurus punctatus | 62.64 | 0.0 | 1167 |
| LLPS-Asm-3319 | Astyanax mexicanus | 62.38 | 0.0 | 1178 |
| LLPS-Scf-1800 | Scleropages formosus | 62.16 | 0.0 | 1165 |
| LLPS-Pof-2091 | Poecilia formosa | 61.74 | 0.0 | 1165 |
| LLPS-Xim-3193 | Xiphophorus maculatus | 61.23 | 0.0 | 1160 |
| LLPS-Gaa-1234 | Gasterosteus aculeatus | 61.21 | 0.0 | 1155 |
| LLPS-Orn-3176 | Oreochromis niloticus | 61.05 | 0.0 | 1155 |
| LLPS-Orl-0315 | Oryzias latipes | 60.86 | 0.0 | 1132 |
| LLPS-Tar-0183 | Takifugu rubripes | 60.19 | 0.0 | 1129 |
| LLPS-Dar-0964 | Danio rerio | 60.14 | 0.0 | 1142 |
| LLPS-Scm-2414 | Scophthalmus maximus | 59.88 | 0.0 | 1119 |
| LLPS-Ten-1393 | Tetraodon nigroviridis | 59.4 | 0.0 | 1125 |
| LLPS-Lac-0581 | Latimeria chalumnae | 58.37 | 0.0 | 914 |
| LLPS-Tag-3123 | Taeniopygia guttata | 45.73 | 1e-62 | 232 |
| LLPS-Anc-2144 | Anolis carolinensis | 44.83 | 2e-61 | 229 |
| LLPS-Cii-1598 | Ciona intestinalis | 44.07 | 2e-56 | 214 |
| LLPS-Drm-1666 | Drosophila melanogaster | 41.2 | 1e-51 | 202 |
| LLPS-Anp-1782 | Anas platyrhynchos | 40.82 | 1e-55 | 211 |