• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Eqc-0620
COPS2

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: COP9 signalosome subunit 2
Gene Name: COPS2
Ensembl Gene: ENSECAG00000024709.2
Ensembl Protein: ENSECAP00000043112.1
Organism: Equus caballus
Taxa ID: 9796
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Chromatin, Nuclear speckle, Nucleolus, Centrosome/Spindle pole bodyPredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MSDMEDDFMC  DDEEDYDLEY  SEDSNSEPNV  DLENQYYNSK  ALKEDDPKAA  LSSFQKVLEL  60
61    EGEKGEWGFK  ALKQMIKINF  KLTNFPEMMN  RYKQLLTYIR  SAVTRNYSEK  SINSILDYIS  120
121   TSKQILMDLL  QEFYETTLEA  LKDAKNDRLW  FKTNTKLGKL  YLEREEYGKL  QKILRQLHQS  180
181   CQTDDGEDDL  KKGTQLLEIY  ALEIQMYTAQ  KNNKKLKALY  EQSLHIKSAI  PHPLIMGVIR  240
241   ECGGKMHLRE  GEFEKAHTDF  FEAFKNYDES  GSPRRTTCLK  YLVLANMLMK  SGINPFDSQE  300
301   AKPYKNDPEI  LAMTNLVSAY  QNNDITEFEK  ILKTNHSNIM  DDPFIREHIE  ELLRNIRTQV  360
361   LIKLIKPYTR  IHIPFISKEL  NIDVADVESL  LVQCILDNTI  HGRIDQVNQL  LELDHQKRGG  420
421   ARYTALDKWT  NQLNSLNQAV  VSKLA  445
Nucleotide CDS Sequence (FASTA)
1     ATGTCTGACA  TGGAGGATGA  TTTCATGTGC  GATGATGAGG  AGGACTACGA  CCTGGAATAC  60
61    TCTGAAGATA  GTAACTCCGA  GCCAAATGTG  GATTTGGAAA  ATCAGTACTA  TAATTCCAAA  120
121   GCGTTAAAAG  AAGATGACCC  AAAAGCAGCA  TTAAGCAGTT  TCCAAAAGGT  TTTGGAGCTT  180
181   GAAGGTGAAA  AAGGAGAATG  GGGATTTAAA  GCACTGAAAC  AAATGATTAA  GATTAACTTC  240
241   AAATTGACAA  ACTTTCCAGA  AATGATGAAC  AGATATAAAC  AACTATTGAC  CTATATTCGG  300
301   AGTGCAGTCA  CAAGAAATTA  TTCTGAAAAA  TCCATTAATT  CTATTCTTGA  TTATATCTCT  360
361   ACTTCTAAAC  AGATGGATTT  ACTGCAGGAA  TTCTATGAAA  CAACACTGGA  AGCTTTGAAA  420
421   GATGCTAAGA  ATGATAGACT  GTGGTTTAAG  ACAAACACAA  AGCTTGGGAA  ATTATATTTA  480
481   GAACGAGAAG  AGTATGGAAA  GCTTCAAAAA  ATTTTACGCC  AGTTGCATCA  GTCCTGCCAG  540
541   ACTGATGATG  GAGAAGATGA  CCTAAAAAAA  GGTACACAGT  TATTAGAAAT  ATATGCTTTG  600
601   GAAATTCAAA  TGTACACGGC  ACAGAAAAAT  AACAAAAAAC  TTAAAGCACT  GTATGAACAG  660
661   TCACTTCACA  TCAAGTCTGC  CATCCCTCAT  CCACTGATCA  TGGGAGTCAT  CAGAGAATGT  720
721   GGTGGTAAAA  TGCACTTGAG  AGAAGGTGAA  TTTGAAAAGG  CACACACTGA  TTTTTTTGAA  780
781   GCTTTCAAGA  ATTATGATGA  ATCTGGAAGT  CCAAGACGAA  CCACTTGCTT  GAAATATTTG  840
841   GTCTTAGCAA  ATATGCTAAT  GAAATCGGGA  ATAAATCCAT  TTGACTCACA  GGAGGCCAAA  900
901   CCGTACAAAA  ATGATCCAGA  AATTCTAGCA  ATGACGAATT  TAGTAAGTGC  CTATCAGAAT  960
961   AATGACATCA  CTGAATTTGA  AAAGATTCTG  AAAACAAATC  ACAGCAACAT  CATGGATGAT  1020
1021  CCTTTCATAA  GGGAACACAT  CGAAGAGCTT  TTGCGAAACA  TCAGAACACA  AGTGCTCATA  1080
1081  AAGTTAATTA  AGCCTTATAC  AAGAATACAT  ATTCCTTTTA  TTTCTAAGGA  GTTAAACATA  1140
1141  GATGTAGCTG  ATGTGGAGAG  CTTGCTGGTG  CAGTGCATAT  TGGATAACAC  TATTCATGGC  1200
1201  CGAATTGATC  AAGTCAACCA  ACTCCTTGAA  CTGGATCATC  AGAAGAGAGG  TGGTGCCCGA  1260
1261  TATACTGCAC  TAGATAAATG  GACCAACCAA  CTAAATTCTC  TCAACCAGGC  TGTAGTCAGT  1320
1321  AAACTGGCTT  AA  1332

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Pes-0505Pelodiscus sinensis99.520.0 855
LLPS-Urm-3743Ursus maritimus99.520.0 855
LLPS-Gaga-2065Gallus gallus99.520.0 855
LLPS-Ict-2886Ictidomys tridecemlineatus99.520.0 855
LLPS-Caf-2153Canis familiaris99.520.0 855
LLPS-Poa-1926Pongo abelii99.520.0 855
LLPS-Cap-0183Cavia porcellus99.520.0 855
LLPS-Fud-2708Fukomys damarensis99.520.0 855
LLPS-Chs-0453Chlorocebus sabaeus99.520.0 855
LLPS-Sus-1032Sus scrofa99.520.0 855
LLPS-Ran-3006Rattus norvegicus99.520.0 855
LLPS-Ova-2248Ovis aries99.520.0 855
LLPS-Mup-1736Mustela putorius furo99.520.0 855
LLPS-Fia-2176Ficedula albicollis99.460.0 759
LLPS-Anp-1587Anas platyrhynchos99.280.0 853
LLPS-Sah-1083Sarcophilus harrisii99.280.0 853
LLPS-Tag-1829Taeniopygia guttata99.050.0 850
LLPS-Asm-3112Astyanax mexicanus99.040.0 852
LLPS-Dar-0237Danio rerio98.80.0 850
LLPS-Leo-1352Lepisosteus oculatus98.80.0 852
LLPS-Scf-3837Scleropages formosus98.80.0 849
LLPS-Orn-1875Oreochromis niloticus98.560.0 848
LLPS-Pof-0206Poecilia formosa98.560.0 848
LLPS-Lac-2068Latimeria chalumnae98.560.0 848
LLPS-Scm-1252Scophthalmus maximus98.560.0 848
LLPS-Orl-1856Oryzias latipes98.560.0 848
LLPS-Xim-3769Xiphophorus maculatus98.560.0 848
LLPS-Gaa-0347Gasterosteus aculeatus98.560.0 848
LLPS-Orc-2254Oryctolagus cuniculus98.350.0 852
LLPS-Rhb-2295Rhinopithecus bieti98.350.0 852
LLPS-Pap-0477Pan paniscus98.350.0 852
LLPS-Pat-2774Pan troglodytes98.350.0 852
LLPS-Hos-1080Homo sapiens98.350.0 852
LLPS-Fec-2168Felis catus98.350.0 852
LLPS-Nol-3162Nomascus leucogenys98.350.0 852
LLPS-Mam-1836Macaca mulatta98.350.0 852
LLPS-Gog-4294Gorilla gorilla98.350.0 852
LLPS-Caj-2103Callithrix jacchus98.350.0 852
LLPS-Mea-0150Mesocricetus auratus98.350.0 852
LLPS-Mum-0711Mus musculus98.350.0 852
LLPS-Maf-0151Macaca fascicularis98.350.0 852
LLPS-Aon-3940Aotus nancymaae98.350.0 852
LLPS-Cea-0493Cercocebus atys98.350.0 852
LLPS-Paa-2459Papio anubis98.350.0 852
LLPS-Mal-0030Mandrillus leucophaeus98.350.0 852
LLPS-Aim-1197Ailuropoda melanoleuca98.350.0 852
LLPS-Bot-2932Bos taurus98.350.0 852
LLPS-Tar-0170Takifugu rubripes98.330.0 847
LLPS-Mod-2242Monodelphis domestica98.110.0 851
LLPS-Man-4323Macaca nemestrina98.110.0 851
LLPS-Loa-2985Loxodonta africana98.110.0 851
LLPS-Anc-2501Anolis carolinensis98.00.0 804
LLPS-Ten-1850Tetraodon nigroviridis97.850.0 836
LLPS-Ora-0094Ornithorhynchus anatinus97.60.0 750
LLPS-Tut-0240Tursiops truncatus97.40.0 829
LLPS-Myl-3921Myotis lucifugus96.930.0 838
LLPS-Otg-1666Otolemur garnettii95.050.0 821
LLPS-Icp-0662Ictalurus punctatus93.850.0 837
LLPS-Cas-2670Carlito syrichta93.50.0 808
LLPS-Meg-1674Meleagris gallopavo92.840.0 786
LLPS-Dio-2218Dipodomys ordii83.490.0 669
LLPS-Drm-1598Drosophila melanogaster83.290.0 718
LLPS-Cii-1886Ciona intestinalis80.860.0 702
LLPS-Cis-0972Ciona savignyi79.670.0 693
LLPS-Sem-0594Selaginella moellendorffii66.670.0 593
LLPS-Glm-2395Glycine max66.430.0 587
LLPS-Cae-1018Caenorhabditis elegans66.330.0 546
LLPS-Phv-2425Phaseolus vulgaris66.190.0 587
LLPS-Nia-0272Nicotiana attenuata66.190.0 588
LLPS-Gor-0828Gossypium raimondii66.190.0 590
LLPS-Hea-1261Helianthus annuus66.190.0 587
LLPS-Php-1750Physcomitrella patens66.190.0 591
LLPS-Met-1816Medicago truncatula66.190.0 584
LLPS-Brd-1494Brachypodium distachyon66.190.0 589
LLPS-Vir-0269Vigna radiata66.190.0 587
LLPS-Via-1305Vigna angularis66.190.0 587
LLPS-Sob-2340Sorghum bicolor65.950.0 589
LLPS-Pot-0506Populus trichocarpa65.870.0 583
LLPS-Thc-0804Theobroma cacao65.870.0 585
LLPS-Orbr-0550Oryza brachyantha65.710.0 587
LLPS-Ors-0023Oryza sativa65.710.0 585
LLPS-Ori-1078Oryza indica65.710.0 585
LLPS-Sei-0615Setaria italica65.710.0 590
LLPS-Hov-0216Hordeum vulgare65.710.0 589
LLPS-Tra-2936Triticum aestivum65.710.0 589
LLPS-Gas-0373Galdieria sulphuraria65.651e-177 511
LLPS-Mae-1538Manihot esculenta65.620.0 585
LLPS-Coc-1126Corchorus capsularis65.620.0 583
LLPS-Prp-2298Prunus persica65.620.0 581
LLPS-Orp-0803Oryza punctata65.470.0 583
LLPS-Mua-1681Musa acuminata65.470.0 580
LLPS-Dac-0426Daucus carota65.470.0 585
LLPS-Sol-1567Solanum lycopersicum65.230.0 580
LLPS-Orm-0304Oryza meridionalis65.190.0 563
LLPS-Orr-1210Oryza rufipogon65.020.0 564
LLPS-Orgl-1642Oryza glumaepatula65.020.0 564
LLPS-Amt-1405Amborella trichopoda64.990.0 580
LLPS-Viv-1538Vitis vinifera64.750.0 572
LLPS-Sot-0190Solanum tuberosum64.750.0 577
LLPS-Abg-1250Absidia glauca64.730.0 552
LLPS-Chc-1142Chondrus crispus63.640.0 548
LLPS-Tru-0727Triticum urartu62.410.0 577
LLPS-Cus-1192Cucumis sativus62.181e-39 150
LLPS-Lep-1492Leersia perrieri62.050.0 571
LLPS-Zem-0535Zea mays61.990.0 570
LLPS-Brr-1037Brassica rapa61.870.0 544
LLPS-Orni-0837Oryza nivara61.680.0 550
LLPS-Orb-2005Oryza barthii61.680.0 550
LLPS-Art-2358Arabidopsis thaliana61.630.0 546
LLPS-Bro-0862Brassica oleracea61.540.0 547
LLPS-Brn-1103Brassica napus61.540.0 547
LLPS-Arl-0274Arabidopsis lyrata61.390.0 545
LLPS-Chr-0648Chlamydomonas reinhardtii60.770.0 541
LLPS-Miv-0145Microbotryum violaceum57.352e-167 488
LLPS-Osl-0120Ostreococcus lucimarinus56.062e-170 493
LLPS-Usm-0990Ustilago maydis55.293e-163 476
LLPS-Spr-0591Sporisorium reilianum54.333e-161 471
LLPS-Asni-1133Aspergillus niger52.881e-155 457
LLPS-Fuv-0614Fusarium verticillioides52.82e-150 444
LLPS-Asfu-1552Aspergillus fumigatus52.772e-156 460
LLPS-Fus-1544Fusarium solani52.665e-150 443
LLPS-Asc-0871Aspergillus clavatus52.537e-155 456
LLPS-Fuo-0225Fusarium oxysporum52.313e-150 444
LLPS-Nef-0670Neosartorya fischeri52.291e-154 455
LLPS-Ast-0379Aspergillus terreus51.925e-154 454
LLPS-Beb-0159Beauveria bassiana51.822e-146 434
LLPS-Cogr-1393Colletotrichum graminicola51.823e-144 428
LLPS-Trv-1417Trichoderma virens51.827e-146 432
LLPS-Cog-0836Colletotrichum gloeosporioides51.592e-145 431
LLPS-Nec-0562Neurospora crassa51.555e-141 420
LLPS-Mao-0755Magnaporthe oryzae51.541e-144 431
LLPS-Asf-1005Aspergillus flavus51.448e-152 448
LLPS-Aso-0645Aspergillus oryzae51.441e-151 447
LLPS-Scs-0885Sclerotinia sclerotiorum51.345e-146 433
LLPS-Gag-1028Gaeumannomyces graminis51.033e-142 424
LLPS-Coo-0681Colletotrichum orbiculare50.981e-144 429
LLPS-Mel-1270Melampsora laricipopulina50.932e-149 441
LLPS-Asn-1000Aspergillus nidulans50.841e-150 445
LLPS-Phn-0434Phaeosphaeria nodorum50.722e-150 445
LLPS-Crn-0683Cryptococcus neoformans50.72e-143 426
LLPS-Map-0943Magnaporthe poae50.386e-141 421
LLPS-Ved-0536Verticillium dahliae50.07e-139 414
LLPS-Dos-0215Dothistroma septosporum50.01e-148 439
LLPS-Zyt-0869Zymoseptoria tritici49.763e-147 436
LLPS-Blg-0636Blumeria graminis49.513e-140 418
LLPS-Pytr-0426Pyrenophora triticirepentis48.921e-140 419
LLPS-Pyt-0699Pyrenophora teres48.922e-140 419
LLPS-Lem-0048Leptosphaeria maculans48.685e-136 407
LLPS-Scp-0305Schizosaccharomyces pombe48.353e-132 395
LLPS-Put-1062Puccinia triticina48.258e-146 432
LLPS-Pug-1045Puccinia graminis47.796e-145 429
LLPS-Tum-0357Tuber melanosporum47.092e-125 377
LLPS-Scc-1366Schizosaccharomyces cryophilus46.375e-122 369
LLPS-Scj-0619Schizosaccharomyces japonicus44.395e-119 362
LLPS-Yal-1220Yarrowia lipolytica35.882e-68 234
LLPS-Cym-0994Cyanidioschyzon merolae31.784e-33 135
LLPS-Kop-0041Komagataella pastoris30.411e-45 172