• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Eqc-0173
AP2B1

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: AP complex subunit beta
Gene Name: AP2B1
Ensembl Gene: ENSECAG00000009033.2
Ensembl Protein: ENSECAP00000007479.2
Organism: Equus caballus
Taxa ID: 9796
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, P-body, Postsynaptic densityPredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MTDSKYFTTN  KKGEIFELKA  ELNNEKKEKR  KEAVKKVIAA  MTVGKDVSSL  FPDVVNCMQT  60
61    DNLELKKLVY  LYLMNYAKSQ  PDMAIMAVNS  FVKDCEDPNP  LIRALAVRTM  GCIRVDKITE  120
121   YLCEPLRKCL  KDEDPYVRKT  AAVCVAKLHD  INAQMVEDQG  FLDSLRDLIA  DSNPMVVANA  180
181   VAALSEISES  HPNSNLLDLN  PQNINKLLTA  LNECTEWGQI  FILDCLSNYN  PKDDREAQSI  240
241   CERVTPRLSH  ANSAVVLSAV  KVLMKFLELL  PKDSDYYNML  LKKLAPPLVT  LLSGEPEVQY  300
301   VALRNINLIV  QKRPEILKQE  IKVFFVKYND  PIYVKLEKLD  IMIRLASQAN  IAQVLAELKE  360
361   YATEVDVDFV  RKAVRAIGRC  AIKVEQSAER  CVSTLLDLIQ  TKVNYVVQEA  IVVIRDIFRK  420
421   YPNKYESIIA  TLCENLDSLD  EPDARAAMIW  IVGEYAERID  NADELLESFL  EGFHDESTQV  480
481   QLTLLTAIVK  LFLKKPSETQ  ELVQQVLSLA  TQDSDNPDLR  DRGYIYWRLL  STDPVTAKEV  540
541   VLSEKPLISE  ETDLIEPTLL  DELICHIGSL  ASVYHKPPNA  FVEGSHGIHR  KHLPIHHGST  600
601   DAGDSPVGTT  TATNLEQPQV  IPSQGDLLGD  LLNLDLGPPV  NVPQVSSMQM  GAVDLLGGGL  660
661   DSLLGSDLGG  GIGGSPAVGQ  SFIPSSVPAT  FAPSPTPAVV  SSGLNDLFEL  STGIGMAPGG  720
721   YVAPKAVWLP  AVKAKGLEIS  GTFTHRQGHI  YMEMNFTNKA  LQHMTDFAIQ  FNKNSFGVIP  780
781   STPLAIHTPL  MPNQSIDVSL  PLNTLGPVMK  MEPLNNLQVA  VKNNIDVFYF  SCLIPLNVLF  840
841   VEDGKMERQV  FLATWKDIPN  ENELQFQIKE  CHLNADTVSS  KLQNNNVYTI  AKRNVEGQDM  900
901   LYQSLKLTNG  IWILAELRIQ  PGNPNYTLSL  KCRAPEVSQY  IYQVYDSILK  N  951
Nucleotide CDS Sequence (FASTA)
1     ATGACTGACT  CCAAATATTT  CACAACCAAT  AAAAAAGGAG  AAATCTTTGA  ATTAAAGGCT  60
61    GAACTCAACA  ATGAAAAGAA  AGAAAAGAGG  AAGGAGGCTG  TGAAGAAAGT  GATTGCTGCT  120
121   ATGACTGTGG  GGAAGGATGT  TAGTTCTCTC  TTTCCAGATG  TAGTGAACTG  TATGCAGACT  180
181   GACAACCTGG  AGCTAAAGAA  GCTTGTGTAT  CTCTACTTGA  TGAACTATGC  CAAGAGTCAG  240
241   CCAGACATGG  CCATCATGGC  TGTCAACAGC  TTTGTGAAGG  ACTGTGAAGA  TCCCAATCCT  300
301   CTGATTCGGG  CCTTGGCAGT  CAGAACCATG  GGGTGCATCC  GGGTGGACAA  GATTACAGAA  360
361   TATCTCTGTG  AGCCCCTCCG  CAAGTGCTTG  AAGGATGAAG  ACCCCTATGT  TCGGAAGACA  420
421   GCAGCAGTCT  GCGTGGCAAA  ACTCCATGAT  ATCAATGCCC  AGATGGTGGA  AGATCAGGGG  480
481   TTTCTGGATT  CTCTGCGGGA  TCTCATAGCA  GATTCAAATC  CAATGGTGGT  GGCTAATGCT  540
541   GTAGCAGCGT  TATCTGAAAT  CAGCGAATCT  CATCCAAACA  GCAACTTACT  CGATCTGAAC  600
601   CCACAGAACA  TTAATAAATT  GCTGACAGCC  CTAAATGAGT  GTACCGAATG  GGGCCAGATT  660
661   TTCATCTTGG  ACTGCCTATC  TAATTACAAC  CCTAAAGATG  ACCGGGAAGC  TCAGAGCATC  720
721   TGTGAACGGG  TAACTCCCCG  GCTATCTCAT  GCCAACTCAG  CAGTGGTGCT  TTCAGCGGTA  780
781   AAAGTCCTAA  TGAAATTTCT  AGAGTTGTTA  CCCAAGGACT  CTGACTACTA  CAATATGCTG  840
841   CTGAAGAAGT  TGGCCCCTCC  GCTTGTCACT  TTGCTGTCTG  GGGAGCCAGA  GGTGCAGTAC  900
901   GTTGCCCTGA  GGAACATCAA  CCTAATTGTT  CAGAAAAGGC  CTGAAATCTT  GAAGCAGGAA  960
961   ATCAAAGTCT  TCTTTGTGAA  ATACAATGAT  CCCATCTATG  TTAAACTAGA  GAAGTTGGAC  1020
1021  ATCATGATTC  GTTTGGCATC  CCAAGCCAAC  ATTGCTCAGG  TTCTGGCAGA  ACTGAAGGAG  1080
1081  TATGCCACAG  AGGTGGATGT  TGACTTTGTT  CGCAAAGCTG  TGCGGGCCAT  TGGACGGTGT  1140
1141  GCCATCAAGG  TGGAGCAATC  TGCAGAGCGC  TGTGTAAGCA  CATTGCTTGA  TCTCATCCAG  1200
1201  ACCAAAGTAA  ATTATGTGGT  CCAAGAGGCG  ATTGTTGTCA  TCAGGGACAT  CTTCCGCAAA  1260
1261  TACCCCAACA  AGTATGAAAG  TATCATTGCC  ACTCTTTGTG  AGAATTTAGA  CTCACTGGAT  1320
1321  GAGCCAGATG  CACGAGCAGC  TATGATTTGG  ATTGTGGGAG  AATATGCTGA  AAGAATTGAC  1380
1381  AATGCAGATG  AGTTACTAGA  GAGCTTCCTG  GAGGGTTTTC  ATGATGAAAG  CACCCAGGTG  1440
1441  CAGCTCACTC  TGCTTACTGC  CATAGTGAAG  CTGTTTCTCA  AGAAACCATC  AGAAACACAG  1500
1501  GAGCTGGTAC  AGCAGGTCTT  GAGTTTGGCA  ACACAGGATT  CTGATAATCC  TGACCTTCGA  1560
1561  GACCGGGGCT  ATATTTATTG  GCGTCTTCTC  TCAACGGACC  CTGTCACAGC  CAAAGAAGTA  1620
1621  GTCTTGTCTG  AGAAGCCACT  GATCTCTGAG  GAGACGGATC  TTATTGAGCC  AACTCTGCTG  1680
1681  GATGAGCTTA  TCTGCCACAT  TGGTTCTTTG  GCTTCTGTGT  ACCATAAGCC  TCCCAATGCT  1740
1741  TTTGTGGAAG  GAAGTCATGG  AATCCATCGC  AAACACTTGC  CCATACATCA  TGGGAGCACT  1800
1801  GATGCAGGTG  ACAGCCCTGT  TGGCACCACC  ACTGCCACCA  ACCTGGAACA  GCCTCAGGTT  1860
1861  ATCCCCTCTC  AAGGTGACCT  TCTGGGGGAC  CTTTTAAACC  TTGACCTTGG  TCCCCCAGTC  1920
1921  AATGTGCCAC  AGGTATCCTC  CATGCAAATG  GGAGCAGTGG  ATCTCTTGGG  AGGAGGACTG  1980
1981  GATAGTCTGC  TTGGCAGTGA  CCTTGGCGGG  GGCATTGGAG  GAAGTCCGGC  AGTGGGACAG  2040
2041  TCCTTCATCC  CATCATCAGT  GCCTGCAACC  TTTGCTCCTT  CACCTACTCC  TGCTGTGGTC  2100
2101  AGCAGTGGCC  TGAATGACCT  GTTTGAACTC  TCCACAGGGA  TAGGCATGGC  ACCTGGTGGA  2160
2161  TATGTGGCTC  CCAAGGCTGT  CTGGCTGCCT  GCAGTAAAGG  CTAAAGGCTT  GGAGATTTCT  2220
2221  GGAACATTTA  CTCACCGCCA  AGGGCACATC  TATATGGAAA  TGAACTTCAC  CAACAAAGCT  2280
2281  CTGCAGCACA  TGACAGACTT  TGCAATCCAG  TTCAACAAGA  ATAGCTTTGG  TGTCATCCCC  2340
2341  AGCACTCCTC  TGGCCATACA  TACACCACTG  ATGCCAAACC  AGAGCATTGA  TGTCTCCCTG  2400
2401  CCTCTCAACA  CGTTGGGCCC  AGTCATGAAG  ATGGAACCTC  TGAATAACCT  GCAGGTGGCT  2460
2461  GTGAAAAACA  ATATTGATGT  CTTCTACTTC  AGCTGCCTCA  TCCCACTCAA  TGTCCTTTTT  2520
2521  GTAGAAGATG  GCAAAATGGA  GCGCCAGGTC  TTCCTTGCAA  CGTGGAAGGA  TATTCCCAAT  2580
2581  GAAAATGAAC  TTCAGTTTCA  GATTAAGGAA  TGTCATTTAA  ATGCCGACAC  TGTTTCCAGC  2640
2641  AAGTTGCAAA  ACAACAATGT  TTATACTATT  GCCAAGAGGA  ATGTGGAAGG  GCAGGACATG  2700
2701  CTGTACCAAT  CTCTGAAGCT  CACCAACGGC  ATTTGGATTT  TGGCTGAGTT  ACGTATCCAG  2760
2761  CCAGGAAACC  CCAATTATAC  GCTGTCGCTG  AAGTGTAGAG  CTCCTGAAGT  CTCTCAGTAC  2820
2821  ATCTATCAGG  TCTACGACAG  CATTTTGAAA  AACTAG  2856

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Caj-1159Callithrix jacchus100.00.01813
LLPS-Chs-2633Chlorocebus sabaeus100.00.01813
LLPS-Mea-3976Mesocricetus auratus100.00.01813
LLPS-Maf-3770Macaca fascicularis100.00.01813
LLPS-Ran-2261Rattus norvegicus100.00.01813
LLPS-Rhb-2422Rhinopithecus bieti100.00.01813
LLPS-Fec-2636Felis catus100.00.01813
LLPS-Pap-2032Pan paniscus100.00.01813
LLPS-Urm-0942Ursus maritimus100.00.01813
LLPS-Pat-3273Pan troglodytes100.00.01813
LLPS-Hos-0981Homo sapiens100.00.01813
LLPS-Loa-0999Loxodonta africana100.00.01813
LLPS-Ict-2734Ictidomys tridecemlineatus100.00.01813
LLPS-Caf-1806Canis familiaris100.00.01813
LLPS-Gog-3707Gorilla gorilla99.890.01811
LLPS-Fud-2933Fukomys damarensis99.890.01811
LLPS-Mum-4070Mus musculus99.890.01811
LLPS-Sus-0897Sus scrofa99.890.01810
LLPS-Mup-3688Mustela putorius furo99.890.01656
LLPS-Tut-0155Tursiops truncatus99.890.01811
LLPS-Bot-2608Bos taurus99.890.01811
LLPS-Dio-3384Dipodomys ordii99.890.01810
LLPS-Orc-2748Oryctolagus cuniculus99.890.01811
LLPS-Nol-1496Nomascus leucogenys99.890.01811
LLPS-Cap-0869Cavia porcellus99.890.01811
LLPS-Poa-0221Pongo abelii99.890.01809
LLPS-Ova-3882Ovis aries99.790.01810
LLPS-Aon-1926Aotus nancymaae99.670.01761
LLPS-Aim-3080Ailuropoda melanoleuca99.370.01799
LLPS-Mod-0419Monodelphis domestica99.370.01803
LLPS-Fia-2782Ficedula albicollis99.050.01800
LLPS-Paa-3361Papio anubis98.950.01788
LLPS-Gaga-1679Gallus gallus98.950.01798
LLPS-Cea-3540Cercocebus atys98.850.01795
LLPS-Man-4320Macaca nemestrina98.850.01795
LLPS-Meg-1364Meleagris gallopavo98.840.01793
LLPS-Anp-0033Anas platyrhynchos98.840.01793
LLPS-Myl-1478Myotis lucifugus97.90.01789
LLPS-Cas-3851Carlito syrichta97.870.01731
LLPS-Tag-2461Taeniopygia guttata97.480.01769
LLPS-Xet-3399Xenopus tropicalis96.650.01753
LLPS-Otg-0611Otolemur garnettii96.110.01721
LLPS-Mam-2818Macaca mulatta95.10.01707
LLPS-Mal-4202Mandrillus leucophaeus94.90.01694
LLPS-Asm-2397Astyanax mexicanus94.850.01730
LLPS-Icp-0045Ictalurus punctatus94.740.01730
LLPS-Scf-1058Scleropages formosus94.640.01725
LLPS-Dar-4095Danio rerio94.530.01722
LLPS-Orl-2316Oryzias latipes93.910.01716
LLPS-Xim-0364Xiphophorus maculatus93.910.01702
LLPS-Ten-2644Tetraodon nigroviridis93.810.01697
LLPS-Orn-3585Oreochromis niloticus93.70.01693
LLPS-Lac-3676Latimeria chalumnae93.70.01689
LLPS-Tar-1320Takifugu rubripes93.60.01692
LLPS-Pof-3918Poecilia formosa93.360.01528
LLPS-Scm-2447Scophthalmus maximus93.180.01689
LLPS-Gaa-2551Gasterosteus aculeatus93.170.01707
LLPS-Leo-1103Lepisosteus oculatus91.90.01705
LLPS-Drm-0572Drosophila melanogaster82.880.01019
LLPS-Anc-2679Anolis carolinensis82.080.01488
LLPS-Sah-2980Sarcophilus harrisii79.010.01329
LLPS-Cae-0043Caenorhabditis elegans76.190.0 971
LLPS-Brn-0991Brassica napus74.70.0 825
LLPS-Brr-2133Brassica rapa74.70.0 825
LLPS-Bro-1131Brassica oleracea74.70.0 825
LLPS-Art-2902Arabidopsis thaliana74.530.0 836
LLPS-Coc-1905Corchorus capsularis74.350.0 833
LLPS-Viv-2339Vitis vinifera74.180.0 853
LLPS-Thc-0002Theobroma cacao74.010.0 832
LLPS-Via-2229Vigna angularis74.010.0 833
LLPS-Gor-1196Gossypium raimondii74.010.0 832
LLPS-Pot-0360Populus trichocarpa73.840.0 851
LLPS-Sei-0849Setaria italica73.670.0 809
LLPS-Lep-2118Leersia perrieri73.670.0 811
LLPS-Tra-2515Triticum aestivum73.490.0 807
LLPS-Phv-0692Phaseolus vulgaris73.490.0 810
LLPS-Glm-2601Glycine max73.340.0 834
LLPS-Dac-1370Daucus carota73.180.0 758
LLPS-Pes-2209Pelodiscus sinensis73.180.01276
LLPS-Hea-1383Helianthus annuus72.670.0 827
LLPS-Zem-2224Zea mays72.60.0 790
LLPS-Cii-2320Ciona intestinalis72.340.01082
LLPS-Nia-2414Nicotiana attenuata72.160.0 839
LLPS-Prp-1955Prunus persica72.110.0 838
LLPS-Sol-1918Solanum lycopersicum72.040.0 838
LLPS-Sot-0978Solanum tuberosum72.040.0 839
LLPS-Amt-1237Amborella trichopoda71.90.0 831
LLPS-Mua-2491Musa acuminata71.450.0 827
LLPS-Mae-2366Manihot esculenta70.990.0 850
LLPS-Cis-1306Ciona savignyi70.690.01050
LLPS-Php-1375Physcomitrella patens70.540.0 808
LLPS-Met-1241Medicago truncatula70.520.0 830
LLPS-Cus-0788Cucumis sativus70.510.0 833
LLPS-Arl-1168Arabidopsis lyrata70.30.0 823
LLPS-Sem-0274Selaginella moellendorffii68.580.0 811
LLPS-Tru-1978Triticum urartu68.210.0 780
LLPS-Abg-0967Absidia glauca66.270.0 755
LLPS-Asc-1477Aspergillus clavatus61.30.0 707
LLPS-Asfu-0725Aspergillus fumigatus60.790.0 703
LLPS-Asf-0633Aspergillus flavus60.740.0 650
LLPS-Nef-1068Neosartorya fischeri60.620.0 701
LLPS-Put-0844Puccinia triticina60.540.0 566
LLPS-Miv-0857Microbotryum violaceum60.470.0 708
LLPS-Aso-0666Aspergillus oryzae60.450.0 703
LLPS-Ast-0982Aspergillus terreus60.450.0 692
LLPS-Asni-1467Aspergillus niger60.270.0 703
LLPS-Tum-1127Tuber melanosporum60.260.0 724
LLPS-Cog-0175Colletotrichum gloeosporioides60.250.0 656
LLPS-Nec-1052Neurospora crassa59.770.0 703
LLPS-Pug-1415Puccinia graminis59.60.0 724
LLPS-Mel-0408Melampsora laricipopulina59.50.0 712
LLPS-Fuv-0720Fusarium verticillioides59.040.0 721
LLPS-Ved-1073Verticillium dahliae59.040.0 665
LLPS-Fuo-0354Fusarium oxysporum59.040.0 720
LLPS-Blg-1103Blumeria graminis58.980.0 723
LLPS-Usm-1105Ustilago maydis58.880.0 700
LLPS-Coo-0015Colletotrichum orbiculare58.710.0 681
LLPS-Gag-0119Gaeumannomyces graminis58.710.0 695
LLPS-Asn-1304Aspergillus nidulans58.540.0 686
LLPS-Crn-1291Cryptococcus neoformans58.520.0 705
LLPS-Gas-1014Galdieria sulphuraria58.460.0 685
LLPS-Mao-0624Magnaporthe oryzae58.40.0 686
LLPS-Fus-0327Fusarium solani58.290.0 719
LLPS-Pytr-0494Pyrenophora triticirepentis58.190.0 684
LLPS-Spr-0715Sporisorium reilianum58.140.0 699
LLPS-Dos-1519Dothistroma septosporum57.450.0 684
LLPS-Zyt-0192Zymoseptoria tritici57.40.0 682
LLPS-Pyt-1043Pyrenophora teres57.170.0 685
LLPS-Beb-0951Beauveria bassiana56.980.0 702
LLPS-Cogr-0229Colletotrichum graminicola56.870.0 662
LLPS-Trv-1625Trichoderma virens56.550.0 652
LLPS-Lem-0528Leptosphaeria maculans56.380.0 663
LLPS-Trr-0942Trichoderma reesei56.380.0 650
LLPS-Vir-1893Vigna radiata56.210.0 943
LLPS-Osl-0191Ostreococcus lucimarinus54.130.0 591
LLPS-Map-0556Magnaporthe poae53.790.0 604
LLPS-Yal-0401Yarrowia lipolytica53.280.0 629
LLPS-Phn-0170Phaeosphaeria nodorum52.262e-157 483
LLPS-Scs-0244Sclerotinia sclerotiorum50.920.0 612
LLPS-Scj-0886Schizosaccharomyces japonicus50.320.0 575
LLPS-Chr-0084Chlamydomonas reinhardtii49.326e-156 488
LLPS-Scc-1007Schizosaccharomyces cryophilus48.825e-175 533
LLPS-Kop-1240Komagataella pastoris48.627e-163 500
LLPS-Chc-1196Chondrus crispus46.683e-171 530
LLPS-Scp-0685Schizosaccharomyces pombe46.180.0 550
LLPS-Asg-0502Ashbya gossypii42.611e-134 427
LLPS-Sac-1597Saccharomyces cerevisiae39.512e-131 420
LLPS-Cym-0782Cyanidioschyzon merolae38.591e-116 387
LLPS-Brd-2068Brachypodium distachyon35.123e-99 337
LLPS-Ora-1966Ornithorhynchus anatinus30.981e-74 266