• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Dos-1321
DOTSEDRAFT_67480

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Nucleolar GTP-binding protein 2
Gene Name: DOTSEDRAFT_67480
Ensembl Gene: DOTSEDRAFT_67480
Ensembl Protein: EME48448
Organism: Dothistroma septosporum
Taxa ID: 675120
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
NucleolusPredicted from orthologs(View)

▼ FUNCTION

GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblEME48448EME48448
UniProtN1PZL1, N1PZL1_DOTSN
GeneBankKB446535EME48448.1

▼ SEQUENCE

Protein Sequence (FASTA)
1     MGTGKKEATR  KVREGKTSDG  MANVKTKGEN  FYRSAKKVKT  LNMFRDGKAQ  RNAQGDITKA  60
61    ASFQSREKPS  ARVEPNRKWF  TNTRVISQDA  LESFRGAVEA  QSKDPYSYLL  KQNKLPMSLI  120
121   HDNKDKERKD  GLTQHKAKIR  IETEKFGDTF  GPKAQRKRPR  LDVSSIANMA  ERSTTDFSKF  180
181   EERRAEARYL  AGLGEGEPNE  SVDASILASG  QIATAREPVF  SKGQSKRIWN  ELYKVIDSSD  240
241   VVIHVLDARD  PDGTRCRSVE  KYIKEEAPHK  HLLFLLNKCD  LVPTSVAAKW  VKHLSKDYPT  300
301   LAFHASMTNS  FGKGTLISLL  RQFSSLHSNR  KQISVGFIGY  PNTGKSSIIN  TLRKKKVCTV  360
361   APIPGETKVW  QYITLMKRIY  LIDCPGIVPP  SMTDSPEDIL  LRGVVRVENV  ENPAQYIPAV  420
421   LAKCKQHHLE  RTYEMKGWSM  DDDTAFTDKP  EQQRTEEGIK  FLEALARKGG  RLLKGGEADM  480
481   DGVAKMVLND  FLRGKIPWFS  PPPTTVGEDE  KLVESRDEAL  GFTHKKRKRE  LGDVGSQAPE  540
541   DEREDENEEA  DVDEDGGFEG  FDEEEEHASE  DTKSGGVQID  PGASDDETPT  590
Nucleotide CDS Sequence (FASTA)
1     ATGGGTACCG  GCAAGAAGGA  GGCGACCCGC  AAGGTCCGCG  AGGGCAAGAC  CAGCGATGGC  60
61    ATGGCTAACG  TCAAGACCAA  GGGCGAGAAC  TTCTACCGAA  GTGCCAAGAA  GGTCAAGACG  120
121   CTCAATATGT  TTCGAGATGG  CAAGGCGCAA  AGGAACGCTC  AAGGAGACAT  CACCAAGGCC  180
181   GCTTCATTCC  AAAGCAGAGA  AAAGCCTTCC  GCGCGAGTCG  AGCCCAACCG  AAAGTGGTTC  240
241   ACCAACACCA  GAGTTATCTC  GCAAGATGCG  CTCGAATCGT  TCCGTGGTGC  GGTGGAGGCG  300
301   CAGAGCAAGG  ATCCATACAG  CTACTTGTTG  AAACAGAACA  AGCTTCCCAT  GAGCTTGATC  360
361   CACGATAACA  AGGACAAAGA  GCGGAAAGAT  GGCCTCACAC  AGCACAAGGC  AAAGATCAGG  420
421   ATAGAGACCG  AAAAGTTTGG  CGACACGTTC  GGACCGAAGG  CACAGCGGAA  GCGACCGCGC  480
481   TTAGATGTAT  CGAGTATTGC  TAACATGGCG  GAGCGATCAA  CAACGGACTT  TTCGAAATTC  540
541   GAAGAACGAC  GGGCAGAGGC  ACGATATCTT  GCTGGACTTG  GCGAGGGTGA  GCCCAATGAG  600
601   TCTGTGGATG  CATCAATCCT  GGCCAGTGGA  CAGATCGCGA  CAGCAAGAGA  ACCAGTCTTT  660
661   TCCAAAGGCC  AAAGCAAACG  AATATGGAAC  GAACTCTACA  AGGTCATCGA  CAGCTCCGAT  720
721   GTGGTGATAC  ACGTTCTAGA  CGCGCGAGAC  CCCGATGGCA  CCCGATGTCG  AAGCGTCGAA  780
781   AAGTATATAA  AAGAAGAGGC  GCCACATAAG  CACTTGCTCT  TCCTGCTGAA  CAAGTGCGAT  840
841   TTGGTGCCAA  CCAGCGTTGC  GGCAAAATGG  GTCAAGCACC  TGTCGAAAGA  CTATCCGACT  900
901   TTGGCTTTTC  ACGCGAGCAT  GACAAACAGC  TTCGGCAAGG  GCACGCTCAT  CTCACTACTG  960
961   CGACAATTCT  CCTCACTGCA  CAGTAACCGC  AAGCAAATCT  CAGTTGGCTT  CATTGGCTAT  1020
1021  CCCAATACCG  GCAAATCGTC  GATAATCAAC  ACCCTCCGGA  AGAAGAAAGT  ATGCACAGTC  1080
1081  GCACCTATCC  CTGGAGAGAC  GAAGGTCTGG  CAGTACATTA  CGCTCATGAA  GCGAATATAT  1140
1141  CTCATCGACT  GTCCCGGTAT  CGTGCCGCCC  TCGATGACCG  ACTCGCCTGA  GGACATCCTG  1200
1201  CTGCGAGGTG  TGGTACGAGT  GGAGAATGTG  GAGAATCCAG  CACAGTACAT  CCCAGCTGTA  1260
1261  CTGGCGAAGT  GCAAGCAGCA  CCATTTGGAG  CGGACTTATG  AGATGAAAGG  CTGGAGCATG  1320
1321  GACGACGACA  CAGCGTTTAC  AGATAAGCCG  GAACAGCAGA  GGACAGAGGA  AGGCATCAAG  1380
1381  TTCCTAGAAG  CACTAGCACG  AAAAGGAGGC  AGACTTCTGA  AAGGTGGCGA  AGCGGACATG  1440
1441  GACGGTGTGG  CCAAGATGGT  ACTGAATGAC  TTCCTGCGAG  GCAAAATCCC  GTGGTTCAGC  1500
1501  CCGCCGCCTA  CGACTGTGGG  TGAAGACGAG  AAGCTGGTGG  AAAGCAGAGA  CGAAGCGCTA  1560
1561  GGCTTTACAC  ATAAGAAGAG  GAAGCGCGAG  CTCGGAGACG  TTGGGTCTCA  GGCTCCTGAA  1620
1621  GATGAGCGGG  AAGATGAGAA  CGAGGAGGCA  GACGTAGACG  AAGATGGTGG  TTTCGAAGGC  1680
1681  TTTGACGAGG  AAGAAGAGCA  TGCCAGTGAG  GATACGAAAT  CCGGCGGTGT  GCAGATAGAT  1740
1741  CCTGGCGCGA  GTGACGACGA  GACGCCGACT  TGA  1773

▼ KEYWORD

ID
Family
Complete proteome
GTP-binding
Nucleotide-binding
Nucleus
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Nucleolus
Molecular Function
GTP binding

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Zyt-0139Zymoseptoria tritici75.540.0 855
LLPS-Scs-0585Sclerotinia sclerotiorum69.250.0 729
LLPS-Asn-0277Aspergillus nidulans68.610.0 695
LLPS-Blg-0360Blumeria graminis68.110.0 712
LLPS-Asc-1483Aspergillus clavatus67.80.0 701
LLPS-Asfu-0366Aspergillus fumigatus67.470.0 711
LLPS-Nef-0387Neosartorya fischeri67.470.0 708
LLPS-Asni-0728Aspergillus niger67.420.0 699
LLPS-Phn-0558Phaeosphaeria nodorum67.230.0 695
LLPS-Fus-0771Fusarium solani66.790.0 705
LLPS-Fuo-0498Fusarium oxysporum66.60.0 697
LLPS-Fuv-0130Fusarium verticillioides66.60.0 696
LLPS-Lem-1228Leptosphaeria maculans65.980.0 697
LLPS-Aso-1183Aspergillus oryzae65.860.0 692
LLPS-Beb-0562Beauveria bassiana65.460.0 689
LLPS-Trv-1340Trichoderma virens65.410.0 688
LLPS-Cogr-1417Colletotrichum graminicola65.230.0 695
LLPS-Ved-0689Verticillium dahliae65.050.0 672
LLPS-Ast-0378Aspergillus terreus65.040.0 680
LLPS-Pyt-1092Pyrenophora teres64.970.0 680
LLPS-Trr-1371Trichoderma reesei64.910.0 690
LLPS-Asf-0673Aspergillus flavus64.780.0 682
LLPS-Pytr-0354Pyrenophora triticirepentis64.590.0 632
LLPS-Cog-1329Colletotrichum gloeosporioides64.540.0 679
LLPS-Coo-1203Colletotrichum orbiculare63.470.0 681
LLPS-Sac-0032Saccharomyces cerevisiae63.130.0 615
LLPS-Asg-0638Ashbya gossypii63.020.0 617
LLPS-Map-0488Magnaporthe poae62.250.0 665
LLPS-Tum-1027Tuber melanosporum62.060.0 590
LLPS-Yal-0593Yarrowia lipolytica62.030.0 615
LLPS-Mao-1320Magnaporthe oryzae61.890.0 640
LLPS-Gag-1065Gaeumannomyces graminis61.020.0 654
LLPS-Kop-1419Komagataella pastoris60.860.0 606
LLPS-Scj-1251Schizosaccharomyces japonicus60.560.0 578
LLPS-Orbr-0826Oryza brachyantha60.484e-113 348
LLPS-Nec-0138Neurospora crassa60.070.0 629
LLPS-Scc-0315Schizosaccharomyces cryophilus58.20.0 579
LLPS-Scp-1435Schizosaccharomyces pombe57.850.0 576
LLPS-Usm-0411Ustilago maydis56.82e-176 525
LLPS-Crn-0200Cryptococcus neoformans56.252e-173 517
LLPS-Spr-1403Sporisorium reilianum56.27e-174 518
LLPS-Abg-1947Absidia glauca55.380.0 541
LLPS-Icp-0237Ictalurus punctatus53.832e-157 476
LLPS-Pug-0585Puccinia graminis53.672e-159 481
LLPS-Orn-2587Oreochromis niloticus53.664e-159 480
LLPS-Miv-0401Microbotryum violaceum53.581e-158 480
LLPS-Put-0302Puccinia triticina53.522e-157 472
LLPS-Xim-0525Xiphophorus maculatus53.461e-157 477
LLPS-Pof-0573Poecilia formosa53.256e-157 475
LLPS-Orl-3646Oryzias latipes53.161e-157 476
LLPS-Asm-0462Astyanax mexicanus53.042e-150 457
LLPS-Scf-0608Scleropages formosus52.565e-156 472
LLPS-Tar-1144Takifugu rubripes52.455e-155 470
LLPS-Orc-1174Oryctolagus cuniculus52.34e-149 455
LLPS-Cea-0142Cercocebus atys52.288e-151 459
LLPS-Dio-0672Dipodomys ordii52.224e-135 418
LLPS-Tut-0680Tursiops truncatus52.072e-150 457
LLPS-Ran-1705Rattus norvegicus51.976e-151 459
LLPS-Sus-0968Sus scrofa51.871e-148 453
LLPS-Ten-0003Tetraodon nigroviridis51.841e-154 468
LLPS-Dar-0211Danio rerio51.831e-156 473
LLPS-Ova-0847Ovis aries51.772e-148 454
LLPS-Fia-0876Ficedula albicollis51.769e-150 456
LLPS-Mum-2196Mus musculus51.764e-150 457
LLPS-Mel-1343Melampsora laricipopulina51.756e-158 478
LLPS-Cap-0872Cavia porcellus51.663e-150 457
LLPS-Cas-0584Carlito syrichta51.665e-150 457
LLPS-Tag-0405Taeniopygia guttata51.657e-150 456
LLPS-Leo-1070Lepisosteus oculatus51.595e-158 477
LLPS-Pes-0129Pelodiscus sinensis51.578e-152 460
LLPS-Bot-0331Bos taurus51.571e-148 454
LLPS-Mea-1203Mesocricetus auratus51.555e-149 454
LLPS-Gaga-0032Gallus gallus51.524e-149 456
LLPS-Ict-0699Ictidomys tridecemlineatus51.451e-148 453
LLPS-Scm-0603Scophthalmus maximus51.435e-152 462
LLPS-Anp-0777Anas platyrhynchos51.342e-147 449
LLPS-Eqc-2188Equus caballus51.242e-149 455
LLPS-Dac-0707Daucus carota51.063e-147 443
LLPS-Sah-1602Sarcophilus harrisii51.038e-148 451
LLPS-Cii-0270Ciona intestinalis50.943e-149 448
LLPS-Mam-0393Macaca mulatta50.89e-151 459
LLPS-Man-1314Macaca nemestrina50.81e-150 458
LLPS-Paa-2218Papio anubis50.83e-150 457
LLPS-Maf-2069Macaca fascicularis50.89e-151 459
LLPS-Chs-0983Chlorocebus sabaeus50.81e-150 458
LLPS-Anc-1804Anolis carolinensis50.734e-146 446
LLPS-Rhb-0439Rhinopithecus bieti50.66e-150 456
LLPS-Mod-1414Monodelphis domestica50.522e-148 452
LLPS-Gaa-0068Gasterosteus aculeatus50.511e-151 461
LLPS-Pap-2078Pan paniscus50.42e-148 454
LLPS-Fec-0552Felis catus50.41e-148 453
LLPS-Gog-1822Gorilla gorilla50.46e-149 454
LLPS-Poa-2528Pongo abelii50.32e-149 455
LLPS-Nol-1783Nomascus leucogenys50.32e-149 455
LLPS-Pat-0878Pan troglodytes50.32e-149 455
LLPS-Hos-1141Homo sapiens50.34e-149 454
LLPS-Aon-2255Aotus nancymaae50.33e-148 452
LLPS-Lac-1254Latimeria chalumnae50.212e-147 450
LLPS-Aim-1907Ailuropoda melanoleuca50.23e-149 455
LLPS-Caj-0994Callithrix jacchus50.24e-148 452
LLPS-Loa-0484Loxodonta africana50.11e-149 456
LLPS-Xet-0831Xenopus tropicalis49.91e-149 456
LLPS-Ora-0986Ornithorhynchus anatinus49.94e-147 450
LLPS-Mup-0368Mustela putorius furo49.75e-149 454
LLPS-Sot-0124Solanum tuberosum49.494e-147 442
LLPS-Fud-0438Fukomys damarensis49.47e-148 451
LLPS-Mal-0971Mandrillus leucophaeus49.381e-136 422
LLPS-Nia-0965Nicotiana attenuata49.369e-144 434
LLPS-Orr-0283Oryza rufipogon49.274e-144 435
LLPS-Ors-0688Oryza sativa49.274e-144 435
LLPS-Orgl-0018Oryza glumaepatula49.274e-144 435
LLPS-Orb-0159Oryza barthii49.274e-144 435
LLPS-Ori-1076Oryza indica49.275e-144 435
LLPS-Orni-0017Oryza nivara49.275e-144 435
LLPS-Myl-0861Myotis lucifugus49.236e-149 454
LLPS-Hea-0375Helianthus annuus49.172e-144 436
LLPS-Orp-0328Oryza punctata49.153e-143 432
LLPS-Org-1454Oryza glaberrima49.061e-143 434
LLPS-Zem-0288Zea mays48.932e-141 429
LLPS-Cae-1382Caenorhabditis elegans48.842e-125 390
LLPS-Otg-3266Otolemur garnettii48.749e-132 410
LLPS-Lep-0868Leersia perrieri48.735e-141 427
LLPS-Phv-0519Phaseolus vulgaris48.61e-114 353
LLPS-Sob-1592Sorghum bicolor48.57e-140 424
LLPS-Sol-0207Solanum lycopersicum48.472e-143 432
LLPS-Chc-1064Chondrus crispus48.444e-123 382
LLPS-Mua-0541Musa acuminata48.425e-133 406
LLPS-Sei-0184Setaria italica48.417e-141 427
LLPS-Thc-0103Theobroma cacao48.416e-141 427
LLPS-Hov-1604Hordeum vulgare48.336e-142 430
LLPS-Brd-0103Brachypodium distachyon48.233e-143 432
LLPS-Art-0423Arabidopsis thaliana48.24e-138 421
LLPS-Brr-0740Brassica rapa48.22e-136 417
LLPS-Met-1508Medicago truncatula48.24e-138 421
LLPS-Brn-1164Brassica napus48.21e-136 417
LLPS-Mae-1295Manihot esculenta48.094e-132 405
LLPS-Cus-1048Cucumis sativus48.023e-144 436
LLPS-Bro-1640Brassica oleracea47.992e-136 417
LLPS-Meg-2374Meleagris gallopavo47.985e-129 402
LLPS-Sem-0907Selaginella moellendorffii47.92e-134 407
LLPS-Gor-0332Gossypium raimondii47.733e-147 444
LLPS-Pot-0161Populus trichocarpa47.672e-140 426
LLPS-Php-0091Physcomitrella patens47.541e-143 437
LLPS-Chr-0271Chlamydomonas reinhardtii47.511e-142 439
LLPS-Viv-1215Vitis vinifera47.491e-143 436
LLPS-Caf-0312Canis familiaris47.281e-149 456
LLPS-Gas-0925Galdieria sulphuraria47.182e-136 416
LLPS-Glm-2599Glycine max47.031e-136 416
LLPS-Prp-0044Prunus persica47.012e-139 422
LLPS-Amt-0505Amborella trichopoda46.962e-133 411
LLPS-Arl-0670Arabidopsis lyrata46.428e-135 412
LLPS-Osl-0014Ostreococcus lucimarinus45.682e-134 407
LLPS-Drm-0356Drosophila melanogaster45.576e-132 408
LLPS-Orm-0538Oryza meridionalis43.42e-112 352
LLPS-Tru-0148Triticum urartu42.892e-97 313
LLPS-Cis-1071Ciona savignyi42.896e-105 338
LLPS-Coc-0475Corchorus capsularis41.622e-112 353
LLPS-Cym-0415Cyanidioschyzon merolae39.156e-107 345
LLPS-Tra-1893Triticum aestivum34.782e-47 180
LLPS-Via-0876Vigna angularis31.626e-49 184