LLPS-Dio-3662
Fyco1
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | FYVE and coiled-coil domain-containing protein 1 |
| Gene Name: | Fyco1 |
| Ensembl Gene: | ENSDORG00000006539.2 |
| Ensembl Protein: | ENSDORP00000006126.2 |
| Organism: | Dipodomys ordii |
| Taxa ID: | 10020 |
| LLPS Type: | LLPS regulator |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Chromatoid body | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSDORT00000006540.2 | ENSDORP00000006126.2 |
| UniProt | A0A1S3GA29, A0A1S3GA29_DIPOR | |
| RefSeq | , XM_013030229.1 | , XP_012885683.1, XP_012885683.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 SSEFKEVGEP ITDDSTSLHK FSYKLEYLLQ FDQKEKASLL GHKKDYWDYF CACLAKVKGA 60 61 NDGIRFVKSI SELRTSLGRG RAFIRYSLVH QRLADTLQQC FMNTKVTSDW YYARSPFLKP 120 121 KLSSDIVGQL YELTEVQFDL ASRGYDLDAA WPTFARYLPK YPPNEALVAP TVILTQDMAS 180 181 SLDLSSQVNN EALEGFDEMR LELEQLEVRE KQLQQRLEQL ERENGELRAA RGIQELQGKL 240 241 QLVEGENAAM RASLLRLRSV EDELAAARAQ ASMRTSSQEP PRVQDEAQEL RRELQSMAGR 300 301 NQLLEGKLQA LQADYQTLQQ REAAIQGSLA SLEAEQASIR HLGDQMEASL LAVRKAKEAM 360 361 KAQVAEKEAA LQSKEQECDR LRQEALKWRQ LAESRDGERK ALEHQCQQQS QLIETLSSQK 420 421 GPEELPRGDS VQLAVLSQAQ LEVHQGEARR LQAEVGDLHA KLRVALGERD KAQSQLTVTE 480 481 ATLQEHKALV QQLKEQNEAL NRAHVQELLH CSEAQGDRQE EQAAVALQAE LLRVACGSED 540 541 AQLAHVELQE QLRRANTDTA ELGIQVCALT AEKERVEGAL ACTAQELQDC KEAAARTRAS 600 601 LESQVVGLQQ ENESLQEQLK RAEEAAGSLA GLQVQLAQAE QQAQSLQEAA HQERDALKFQ 660 661 LSTEIMDYQS QLKTANEEGE SLRAQLDERG QQLQAAREAV DELKVSATLE EKLSCTSSRL 720 721 AECQACALQK EQEAAALREQ LDRTQKELTK ASAKIQEYYT KLCQEVTDRE RNDQKLLADL 780 781 DDLNRTKKYL EERLIELLRD KDALWQKSDA LEFQQKLSAE ERCVGDAEAT HCHDCRREFG 840 841 WMVRRHHCRI CGRAFCYYCC NNYVLAKPGG KKERCCRACF HKCSDGPGSP GSASSGASQG 900 901 EASPAPSPAR TRPPAIEGPG AAADCRSPDD AVFDIITDEE LCQIQESGSS LPETPTETES 960 961 PEPSVA 966 |
| Nucleotide CDS Sequence (FASTA) |
1 AGCAGCGAAT TCAAGGAAGT GGGAGAGCCC ATCACCGATG ACAGCACCAG CTTGCACAAG 60 61 TTTTCCTACA AGCTCGAGTA TCTCCTGCAA TTTGACCAGA AGGAGAAGGC CAGCCTCTTG 120 121 GGACACAAGA AAGACTACTG GGACTACTTC TGTGCTTGCC TGGCCAAAGT GAAAGGGGCC 180 181 AATGACGGGA TCCGCTTCGT CAAGTCCATC TCGGAGCTCC GGACGTCTCT GGGGAGAGGA 240 241 AGAGCCTTCA TCCGCTACTC GCTGGTGCAC CAGAGGCTGG CAGACACCTT ACAGCAATGC 300 301 TTCATGAACA CTAAAGTGAC CAGTGACTGG TACTATGCAC GAAGCCCTTT TCTGAAGCCC 360 361 AAGCTGAGCT CCGACATCGT GGGCCAACTC TATGAGCTGA CCGAGGTTCA GTTTGACCTG 420 421 GCCTCCAGAG GCTATGACTT AGATGCTGCT TGGCCGACGT TTGCCAGGTA CTTACCAAAA 480 481 TACCCCCCAA ACGAGGCGCT GGTGGCTCCA ACTGTCATCC TAACTCAGGA TATGGCTTCC 540 541 AGCTTGGACC TCAGCAGCCA GGTAAACAAC GAGGCGCTGG AGGGCTTTGA CGAGATGCGG 600 601 CTGGAGCTGG AGCAGCTGGA GGTGCGGGAG AAGCAGCTTC AGCAGCGCCT GGAGCAGCTG 660 661 GAGCGGGAGA ACGGGGAGCT GCGGGCCGCC CGGGGGATCC AGGAGCTGCA AGGCAAGCTC 720 721 CAGCTGGTGG AAGGCGAGAA CGCCGCCATG CGGGCGTCGC TGCTGCGCCT GCGCTCGGTG 780 781 GAGGACGAGC TGGCGGCGGC CAGGGCGCAG GCGAGCATGC GCACGAGCAG CCAGGAGCCG 840 841 CCGCGGGTCC AGGACGAGGC GCAGGAGCTG AGGCGCGAGC TGCAGAGCAT GGCCGGGCGC 900 901 AACCAGCTCC TGGAGGGCAA GCTGCAGGCC CTGCAGGCCG ACTACCAGAC GCTGCAGCAG 960 961 CGCGAGGCGG CCATCCAGGG CTCCCTGGCC TCGCTGGAGG CCGAGCAGGC CAGCATCCGC 1020 1021 CACCTGGGCG ACCAGATGGA GGCCAGCCTC CTGGCGGTGC GGAAGGCCAA GGAGGCCATG 1080 1081 AAGGCGCAGG TGGCGGAGAA GGAGGCGGCC CTGCAGAGCA AGGAGCAGGA ATGCGATCGC 1140 1141 TTGCGCCAGG AGGCCCTGAA GTGGCGGCAG CTGGCCGAGT CCCGGGACGG GGAGCGCAAG 1200 1201 GCCCTGGAGC ACCAGTGCCA GCAGCAGAGC CAGCTGATCG AGACCCTCAG CAGCCAGAAA 1260 1261 GGCCCCGAGG AGCTGCCCCG GGGCGACAGC GTGCAGCTGG CCGTGCTGTC TCAGGCCCAG 1320 1321 CTGGAGGTCC ACCAAGGGGA GGCCCGGCGG CTGCAGGCCG AGGTGGGCGA CCTGCACGCC 1380 1381 AAGCTGCGGG TGGCCCTGGG CGAGCGCGAC AAGGCGCAGA GCCAGCTGAC GGTGACGGAG 1440 1441 GCCACCCTGC AGGAGCACAA GGCCCTGGTG CAGCAGCTGA AGGAGCAGAA CGAGGCGCTG 1500 1501 AACCGGGCCC ACGTGCAGGA GCTGCTGCAC TGCTCCGAGG CCCAAGGGGA CCGGCAGGAG 1560 1561 GAGCAGGCGG CTGTGGCCCT GCAGGCCGAG CTGCTGCGCG TGGCGTGCGG CTCCGAGGAC 1620 1621 GCGCAGCTGG CGCACGTCGA GCTGCAGGAG CAGCTGCGCC GGGCCAACAC CGACACGGCC 1680 1681 GAGCTGGGCA TCCAGGTGTG CGCGCTGACG GCAGAGAAGG AGCGGGTGGA GGGCGCGCTG 1740 1741 GCCTGCACCG CGCAGGAGCT GCAGGACTGC AAAGAGGCGG CGGCCAGGAC GAGGGCCAGC 1800 1801 CTGGAAAGCC AGGTCGTGGG CCTCCAGCAA GAGAACGAGA GTCTGCAGGA GCAGCTCAAG 1860 1861 AGGGCCGAGG AGGCAGCCGG CTCCCTGGCT GGCCTGCAGG TCCAGCTGGC TCAAGCCGAG 1920 1921 CAGCAGGCCC AGAGCCTGCA GGAGGCCGCA CACCAGGAGC GGGACGCCCT CAAGTTCCAG 1980 1981 CTGAGCACCG AGATCATGGA TTACCAAAGC CAGCTGAAGA CAGCCAACGA AGAGGGCGAG 2040 2041 AGCCTCAGGG CGCAGCTGGA CGAGCGGGGC CAGCAGCTGC AGGCGGCCCG GGAGGCCGTG 2100 2101 GACGAGTTGA AGGTCAGTGC AACCTTGGAG GAGAAGCTGA GCTGCACCAG CAGCCGCCTG 2160 2161 GCCGAGTGCC AGGCCTGCGC GCTGCAGAAG GAGCAGGAGG CGGCCGCCCT GCGCGAGCAG 2220 2221 CTAGACCGAA CACAGAAGGA GCTGACCAAA GCCTCAGCAA AAATCCAAGA GTATTACACC 2280 2281 AAACTCTGCC AAGAGGTGAC CGACCGGGAG AGGAACGACC AGAAGCTGCT CGCCGACCTG 2340 2341 GACGACCTGA ACCGAACGAA GAAGTACCTG GAGGAGAGGC TCATAGAGCT GCTCAGGGAC 2400 2401 AAGGACGCGC TGTGGCAGAA GTCGGACGCC CTGGAGTTCC AGCAGAAGCT CAGCGCCGAG 2460 2461 GAGCGGTGCG TGGGGGACGC GGAGGCGACC CACTGCCACG ACTGCAGGCG CGAGTTCGGC 2520 2521 TGGATGGTGC GCCGCCACCA CTGCAGGATC TGCGGGCGCG CCTTCTGTTA CTACTGCTGC 2580 2581 AACAACTACG TGCTTGCCAA GCCCGGCGGC AAGAAGGAGC GCTGCTGCCG GGCCTGCTTC 2640 2641 CACAAGTGCA GCGACGGGCC CGGCTCCCCC GGCAGCGCCA GCTCCGGCGC CAGCCAGGGC 2700 2701 GAGGCCAGCC CCGCGCCGTC CCCCGCCCGG ACCCGGCCGC CAGCCATCGA GGGCCCAGGG 2760 2761 GCCGCGGCTG ACTGCAGGTC CCCGGACGAC GCGGTGTTTG ACATCATCAC GGACGAGGAG 2820 2821 CTGTGTCAGA TCCAGGAGTC GGGCTCCTCC CTGCCCGAAA CACCCACGGA AACCGAGTCT 2880 2881 CCCGAGCCGA GCGTGGCT 2898 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Pof-0896 | Poecilia formosa | 85.06 | 3e-85 | 305 |
| LLPS-Xim-3774 | Xiphophorus maculatus | 85.06 | 1e-85 | 306 |
| LLPS-Ict-4676 | Ictidomys tridecemlineatus | 83.25 | 1e-106 | 368 |
| LLPS-Ran-4822 | Rattus norvegicus | 82.69 | 8e-106 | 365 |
| LLPS-Scm-1797 | Scophthalmus maximus | 82.47 | 1e-83 | 300 |
| LLPS-Lac-2778 | Latimeria chalumnae | 82.47 | 3e-84 | 302 |
| LLPS-Cap-1127 | Cavia porcellus | 82.3 | 4e-104 | 360 |
| LLPS-Orn-1906 | Oreochromis niloticus | 81.82 | 2e-82 | 296 |
| LLPS-Caj-3787 | Callithrix jacchus | 81.82 | 9e-106 | 365 |
| LLPS-Myl-2915 | Myotis lucifugus | 81.82 | 2e-105 | 364 |
| LLPS-Ten-2008 | Tetraodon nigroviridis | 81.41 | 2e-82 | 297 |
| LLPS-Leo-3832 | Lepisosteus oculatus | 81.41 | 2e-83 | 300 |
| LLPS-Cas-3445 | Carlito syrichta | 81.34 | 2e-104 | 362 |
| LLPS-Mum-2887 | Mus musculus | 81.34 | 5e-104 | 360 |
| LLPS-Gaa-1248 | Gasterosteus aculeatus | 81.17 | 4e-80 | 290 |
| LLPS-Man-3074 | Macaca nemestrina | 80.86 | 4e-104 | 361 |
| LLPS-Rhb-4401 | Rhinopithecus bieti | 80.86 | 7e-104 | 360 |
| LLPS-Otg-0567 | Otolemur garnettii | 80.86 | 4e-98 | 343 |
| LLPS-Mam-4507 | Macaca mulatta | 80.86 | 4e-104 | 360 |
| LLPS-Nol-4293 | Nomascus leucogenys | 80.86 | 3e-104 | 361 |
| LLPS-Maf-2073 | Macaca fascicularis | 80.86 | 3e-104 | 361 |
| LLPS-Chs-3397 | Chlorocebus sabaeus | 80.86 | 5e-104 | 360 |
| LLPS-Mal-4695 | Mandrillus leucophaeus | 80.86 | 3e-104 | 361 |
| LLPS-Paa-4419 | Papio anubis | 80.86 | 4e-104 | 361 |
| LLPS-Caf-2120 | Canis familiaris | 80.48 | 2e-102 | 356 |
| LLPS-Loa-2017 | Loxodonta africana | 80.38 | 2e-105 | 364 |
| LLPS-Hos-3659 | Homo sapiens | 80.38 | 1e-103 | 359 |
| LLPS-Pat-4725 | Pan troglodytes | 80.38 | 1e-103 | 359 |
| LLPS-Urm-0586 | Ursus maritimus | 80.38 | 8e-104 | 359 |
| LLPS-Poa-3069 | Pongo abelii | 80.38 | 2e-103 | 358 |
| LLPS-Eqc-3348 | Equus caballus | 80.38 | 2e-104 | 361 |
| LLPS-Sus-1180 | Sus scrofa | 80.38 | 1e-103 | 359 |
| LLPS-Cea-0787 | Cercocebus atys | 80.38 | 4e-103 | 358 |
| LLPS-Aon-4710 | Aotus nancymaae | 80.38 | 3e-104 | 361 |
| LLPS-Bot-2483 | Bos taurus | 80.38 | 1e-102 | 356 |
| LLPS-Ova-4135 | Ovis aries | 80.38 | 3e-102 | 353 |
| LLPS-Dar-1325 | Danio rerio | 80.13 | 1e-81 | 295 |
| LLPS-Pap-0847 | Pan paniscus | 79.9 | 2e-103 | 358 |
| LLPS-Orc-3329 | Oryctolagus cuniculus | 79.9 | 8e-104 | 360 |
| LLPS-Mea-3917 | Mesocricetus auratus | 79.9 | 9e-104 | 359 |
| LLPS-Gog-2288 | Gorilla gorilla | 79.9 | 3e-103 | 358 |
| LLPS-Scf-1961 | Scleropages formosus | 79.49 | 3e-80 | 290 |
| LLPS-Fud-3489 | Fukomys damarensis | 79.43 | 2e-100 | 349 |
| LLPS-Asm-2866 | Astyanax mexicanus | 78.85 | 3e-80 | 291 |
| LLPS-Icp-0592 | Ictalurus punctatus | 78.85 | 2e-78 | 284 |
| LLPS-Mod-3844 | Monodelphis domestica | 76.67 | 1e-99 | 347 |
| LLPS-Orl-3424 | Oryzias latipes | 76.28 | 2e-76 | 279 |
| LLPS-Anp-1427 | Anas platyrhynchos | 72.51 | 4e-93 | 328 |
| LLPS-Tag-1948 | Taeniopygia guttata | 72.04 | 2e-93 | 329 |
| LLPS-Mup-0398 | Mustela putorius furo | 71.77 | 1e-80 | 291 |
| LLPS-Tar-1367 | Takifugu rubripes | 71.6 | 1e-75 | 276 |
| LLPS-Gaga-1605 | Gallus gallus | 71.43 | 4e-93 | 328 |
| LLPS-Fia-3088 | Ficedula albicollis | 71.09 | 1e-91 | 324 |
| LLPS-Ora-2807 | Ornithorhynchus anatinus | 61.89 | 3e-100 | 350 |
| LLPS-Sah-2212 | Sarcophilus harrisii | 53.73 | 0.0 | 575 |
| LLPS-Pes-3441 | Pelodiscus sinensis | 52.2 | 3e-88 | 298 |
| LLPS-Cii-1528 | Ciona intestinalis | 51.63 | 1e-42 | 173 |
| LLPS-Anc-2570 | Anolis carolinensis | 48.41 | 1e-94 | 333 |
| LLPS-Drm-1772 | Drosophila melanogaster | 45.65 | 1e-06 | 57.4 |
| LLPS-Cus-0754 | Cucumis sativus | 42.11 | 3e-07 | 59.3 |
| LLPS-Xet-3278 | Xenopus tropicalis | 40.48 | 3e-06 | 55.5 |
| LLPS-Hea-1714 | Helianthus annuus | 40.35 | 1e-07 | 60.1 |
| LLPS-Meg-0828 | Meleagris gallopavo | 39.66 | 2e-06 | 56.2 |
| LLPS-Aim-1986 | Ailuropoda melanoleuca | 39.66 | 3e-06 | 55.8 |
| LLPS-Fec-1954 | Felis catus | 31.03 | 2e-07 | 59.7 |
| LLPS-Tut-2059 | Tursiops truncatus | 25.97 | 5e-09 | 64.3 |