LLPS-Dio-3107
Timm23
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Mitochondrial import inner membrane translocase subunit TIM23 |
| Gene Name: | Timm23 |
| Ensembl Gene: | ENSDORG00000027219.1 |
| Ensembl Protein: | ENSDORP00000017159.1 |
| Organism: | Dipodomys ordii |
| Taxa ID: | 10020 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Nucleolus | Predicted from orthologs | (View) |
▼ FUNCTION
| Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSDORT00000030671.1 | ENSDORP00000017159.1 |
| UniProt | A0A1S3GSK9, A0A1S3GSK9_DIPOR | |
| RefSeq | , XM_013036221.1 | , XP_012891675.1, XP_012891675.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MEGGGGSGNK TTGGLAGFFG ASGAGYSHAD LAGVPLTGMN PLSPYLNVDP RYLVQDTDEF 60 61 ILPTGANKTR GRFELAFFTI GGCCMTGAAF GAVNGLRLGL KETQNMAWSK PRNVQILNMV 120 121 TRQGALWANT LGSLALLYSA FGVIIEKSRG AEDDLNTVAA GTLTGMLYKC TGGLRGVARG 180 181 GLAGLTLTSL YALYNNWEHM KGSLLQQSL 209 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGAGGGTG GCGGGGGAAG TGGCAACAAG ACCACCGGAG GGCTGGCCGG CTTCTTTGGA 60 61 GCCAGTGGGG CCGGCTACTC GCACGCGGAT TTGGCCGGCG TGCCGCTAAC TGGTATGAAC 120 121 CCTCTATCTC CTTATTTAAA TGTGGATCCA CGATATCTGG TGCAGGACAC CGATGAGTTT 180 181 ATTTTACCTA CTGGAGCCAA TAAAACCCGG GGCAGATTTG AACTAGCCTT CTTTACTATT 240 241 GGAGGATGTT GCATGACAGG GGCTGCATTT GGAGCAGTGA ATGGTCTTCG TCTAGGATTG 300 301 AAGGAAACCC AGAACATGGC CTGGTCCAAA CCAAGAAACG TACAGATTTT GAATATGGTA 360 361 ACTAGGCAAG GAGCACTTTG GGCTAATACT TTAGGTTCTC TGGCTTTGCT CTATAGTGCA 420 421 TTTGGTGTTA TTATTGAGAA ATCACGAGGA GCAGAAGATG ACCTGAACAC AGTAGCAGCT 480 481 GGAACTTTGA CAGGCATGTT GTACAAATGT ACAGGTGGCC TTCGAGGGGT AGCACGAGGT 540 541 GGACTGGCAG GACTAACACT TACCAGCCTC TATGCACTGT ATAACAACTG GGAGCACATG 600 601 AAAGGCTCCT TGCTCCAACA GTCACTTTGA 630 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Integral component of membrane | |
Cellular Component | TIM23 mitochondrial import inner membrane translocase complex | |
Molecular Function | P-P-bond-hydrolysis-driven protein transmembrane transporter activity | |
Biological Process | Intracellular protein transport |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Sus-3777 | Sus scrofa | 98.91 | 3e-110 | 322 |
| LLPS-Myl-1400 | Myotis lucifugus | 98.37 | 1e-109 | 320 |
| LLPS-Poa-3605 | Pongo abelii | 97.93 | 2e-101 | 298 |
| LLPS-Mal-1050 | Mandrillus leucophaeus | 97.93 | 3e-101 | 297 |
| LLPS-Orc-1759 | Oryctolagus cuniculus | 97.83 | 4e-110 | 321 |
| LLPS-Cap-0720 | Cavia porcellus | 97.83 | 2e-109 | 320 |
| LLPS-Ict-1039 | Ictidomys tridecemlineatus | 97.83 | 9e-109 | 318 |
| LLPS-Fud-2120 | Fukomys damarensis | 97.83 | 6e-109 | 318 |
| LLPS-Urm-1497 | Ursus maritimus | 97.28 | 3e-109 | 319 |
| LLPS-Pat-2435 | Pan troglodytes | 97.28 | 1e-109 | 320 |
| LLPS-Hos-2308 | Homo sapiens | 97.28 | 1e-109 | 320 |
| LLPS-Rhb-4788 | Rhinopithecus bieti | 97.28 | 1e-109 | 320 |
| LLPS-Eqc-2622 | Equus caballus | 97.28 | 2e-109 | 320 |
| LLPS-Mam-3508 | Macaca mulatta | 97.28 | 1e-109 | 320 |
| LLPS-Cas-3333 | Carlito syrichta | 97.28 | 4e-109 | 318 |
| LLPS-Nol-2846 | Nomascus leucogenys | 97.28 | 7e-110 | 321 |
| LLPS-Maf-4335 | Macaca fascicularis | 97.28 | 1e-109 | 320 |
| LLPS-Chs-2966 | Chlorocebus sabaeus | 97.28 | 1e-109 | 320 |
| LLPS-Cea-1369 | Cercocebus atys | 97.28 | 1e-109 | 320 |
| LLPS-Paa-2485 | Papio anubis | 97.28 | 1e-109 | 320 |
| LLPS-Ova-3174 | Ovis aries | 97.28 | 9e-110 | 320 |
| LLPS-Aim-0635 | Ailuropoda melanoleuca | 97.28 | 3e-109 | 319 |
| LLPS-Caf-4332 | Canis familiaris | 97.24 | 6e-101 | 297 |
| LLPS-Tut-0798 | Tursiops truncatus | 97.11 | 2e-100 | 295 |
| LLPS-Fec-3090 | Felis catus | 96.74 | 4e-109 | 318 |
| LLPS-Man-4260 | Macaca nemestrina | 96.74 | 2e-109 | 320 |
| LLPS-Mum-4889 | Mus musculus | 96.74 | 5e-108 | 316 |
| LLPS-Bot-4828 | Bos taurus | 96.74 | 3e-109 | 319 |
| LLPS-Mup-2307 | Mustela putorius furo | 96.74 | 7e-109 | 318 |
| LLPS-Mea-3030 | Mesocricetus auratus | 96.59 | 2e-102 | 301 |
| LLPS-Ran-4051 | Rattus norvegicus | 95.65 | 3e-107 | 314 |
| LLPS-Fia-3443 | Ficedula albicollis | 95.52 | 5e-90 | 268 |
| LLPS-Tag-3093 | Taeniopygia guttata | 94.78 | 8e-90 | 268 |
| LLPS-Loa-3572 | Loxodonta africana | 93.68 | 4e-97 | 287 |
| LLPS-Anp-2494 | Anas platyrhynchos | 93.38 | 8e-90 | 268 |
| LLPS-Ora-3002 | Ornithorhynchus anatinus | 93.33 | 3e-90 | 268 |
| LLPS-Aon-1302 | Aotus nancymaae | 93.23 | 6e-106 | 311 |
| LLPS-Caj-1166 | Callithrix jacchus | 93.23 | 6e-106 | 311 |
| LLPS-Mod-3007 | Monodelphis domestica | 92.39 | 5e-104 | 306 |
| LLPS-Anc-3230 | Anolis carolinensis | 92.39 | 2e-104 | 307 |
| LLPS-Sah-3468 | Sarcophilus harrisii | 91.95 | 3e-97 | 287 |
| LLPS-Gaga-3083 | Gallus gallus | 91.85 | 1e-104 | 307 |
| LLPS-Gog-4299 | Gorilla gorilla | 91.47 | 7e-80 | 242 |
| LLPS-Pes-0844 | Pelodiscus sinensis | 90.76 | 4e-103 | 306 |
| LLPS-Lac-2193 | Latimeria chalumnae | 86.96 | 2e-97 | 289 |
| LLPS-Leo-1882 | Lepisosteus oculatus | 85.33 | 3e-95 | 283 |
| LLPS-Orn-3499 | Oreochromis niloticus | 84.83 | 1e-93 | 280 |
| LLPS-Scf-2863 | Scleropages formosus | 84.18 | 6e-92 | 275 |
| LLPS-Icp-3083 | Ictalurus punctatus | 83.71 | 1e-91 | 274 |
| LLPS-Dar-3632 | Danio rerio | 83.05 | 4e-90 | 270 |
| LLPS-Tar-4020 | Takifugu rubripes | 82.58 | 1e-91 | 274 |
| LLPS-Xet-2736 | Xenopus tropicalis | 82.26 | 1e-88 | 267 |
| LLPS-Ten-2579 | Tetraodon nigroviridis | 82.02 | 1e-89 | 269 |
| LLPS-Xim-2689 | Xiphophorus maculatus | 82.02 | 6e-92 | 275 |
| LLPS-Gaa-0645 | Gasterosteus aculeatus | 82.02 | 9e-90 | 270 |
| LLPS-Pof-4199 | Poecilia formosa | 81.46 | 1e-91 | 275 |
| LLPS-Asm-2061 | Astyanax mexicanus | 81.46 | 6e-91 | 273 |
| LLPS-Scm-2225 | Scophthalmus maximus | 80.98 | 1e-91 | 274 |
| LLPS-Orl-3919 | Oryzias latipes | 80.34 | 3e-90 | 271 |
| LLPS-Otg-4604 | Otolemur garnettii | 65.76 | 6e-70 | 217 |
| LLPS-Drm-1673 | Drosophila melanogaster | 53.08 | 1e-34 | 128 |
| LLPS-Pug-1268 | Puccinia graminis | 47.27 | 3e-09 | 58.9 |
| LLPS-Put-0941 | Puccinia triticina | 47.27 | 2e-09 | 59.3 |
| LLPS-Mel-1519 | Melampsora laricipopulina | 45.45 | 5e-08 | 55.8 |
| LLPS-Miv-0474 | Microbotryum violaceum | 40.35 | 3e-06 | 50.4 |
| LLPS-Scc-1515 | Schizosaccharomyces cryophilus | 39.22 | 2e-11 | 63.9 |
| LLPS-Cii-1845 | Ciona intestinalis | 37.5 | 4e-19 | 86.7 |
| LLPS-Gag-0700 | Gaeumannomyces graminis | 36.9 | 3e-07 | 53.1 |
| LLPS-Mao-1578 | Magnaporthe oryzae | 36.9 | 4e-07 | 52.8 |
| LLPS-Map-0558 | Magnaporthe poae | 36.9 | 1e-07 | 54.3 |
| LLPS-Cus-0324 | Cucumis sativus | 36.15 | 2e-10 | 60.8 |
| LLPS-Org-1046 | Oryza glaberrima | 36.08 | 2e-06 | 50.4 |
| LLPS-Orb-2299 | Oryza barthii | 36.08 | 2e-06 | 50.4 |
| LLPS-Cis-2067 | Ciona savignyi | 35.94 | 5e-18 | 83.6 |
| LLPS-Scp-0298 | Schizosaccharomyces pombe | 35.82 | 4e-11 | 63.2 |
| LLPS-Dac-0142 | Daucus carota | 35.42 | 1e-06 | 50.8 |
| LLPS-Cog-0532 | Colletotrichum gloeosporioides | 35.35 | 5e-07 | 52.4 |
| LLPS-Glm-2990 | Glycine max | 34.46 | 1e-10 | 61.6 |
| LLPS-Aso-0107 | Aspergillus oryzae | 34.31 | 1e-09 | 59.3 |
| LLPS-Asf-1108 | Aspergillus flavus | 34.31 | 1e-09 | 58.9 |
| LLPS-Scj-1239 | Schizosaccharomyces japonicus | 34.31 | 3e-13 | 69.3 |
| LLPS-Fus-1532 | Fusarium solani | 34.11 | 3e-09 | 58.5 |
| LLPS-Fuo-0530 | Fusarium oxysporum | 34.11 | 2e-09 | 58.9 |
| LLPS-Fuv-1595 | Fusarium verticillioides | 34.11 | 2e-09 | 58.9 |
| LLPS-Ved-0504 | Verticillium dahliae | 33.33 | 2e-09 | 59.3 |
| LLPS-Usm-0148 | Ustilago maydis | 33.03 | 3e-07 | 53.1 |
| LLPS-Orm-1668 | Oryza meridionalis | 32.64 | 5e-06 | 50.1 |
| LLPS-Asfu-1123 | Aspergillus fumigatus | 32.35 | 9e-10 | 59.7 |
| LLPS-Cogr-1088 | Colletotrichum graminicola | 32.12 | 5e-10 | 60.8 |
| LLPS-Coo-1090 | Colletotrichum orbiculare | 32.12 | 3e-09 | 58.9 |
| LLPS-Met-2346 | Medicago truncatula | 31.97 | 4e-08 | 54.7 |
| LLPS-Beb-0821 | Beauveria bassiana | 31.93 | 3e-09 | 58.9 |
| LLPS-Spr-0493 | Sporisorium reilianum | 31.78 | 4e-07 | 53.1 |
| LLPS-Cae-1959 | Caenorhabditis elegans | 31.58 | 3e-14 | 72.8 |
| LLPS-Nef-1356 | Neosartorya fischeri | 31.39 | 2e-09 | 58.9 |
| LLPS-Asc-0677 | Aspergillus clavatus | 31.39 | 3e-09 | 58.2 |
| LLPS-Asni-1509 | Aspergillus niger | 31.39 | 6e-09 | 58.2 |
| LLPS-Phn-1153 | Phaeosphaeria nodorum | 31.37 | 7e-07 | 52.0 |
| LLPS-Blg-1332 | Blumeria graminis | 31.37 | 4e-07 | 52.4 |
| LLPS-Crn-0071 | Cryptococcus neoformans | 31.16 | 3e-06 | 50.4 |
| LLPS-Asn-0826 | Aspergillus nidulans | 31.16 | 9e-10 | 59.7 |
| LLPS-Trv-0950 | Trichoderma virens | 31.09 | 2e-07 | 53.5 |
| LLPS-Ast-0746 | Aspergillus terreus | 30.88 | 7e-10 | 59.7 |
| LLPS-Amt-0370 | Amborella trichopoda | 30.88 | 4e-07 | 52.0 |
| LLPS-Phv-2228 | Phaseolus vulgaris | 30.77 | 6e-07 | 51.6 |
| LLPS-Via-1201 | Vigna angularis | 30.77 | 1e-06 | 50.8 |
| LLPS-Vir-1607 | Vigna radiata | 30.77 | 8e-08 | 53.9 |
| LLPS-Zyt-1361 | Zymoseptoria tritici | 30.33 | 2e-07 | 53.9 |
| LLPS-Trr-1175 | Trichoderma reesei | 30.25 | 4e-07 | 52.8 |
| LLPS-Abg-1113 | Absidia glauca | 30.1 | 1e-08 | 57.0 |
| LLPS-Nec-1103 | Neurospora crassa | 29.93 | 3e-07 | 53.1 |
| LLPS-Dos-1504 | Dothistroma septosporum | 29.71 | 2e-07 | 53.1 |
| LLPS-Lem-1217 | Leptosphaeria maculans | 29.33 | 6e-07 | 52.4 |
| LLPS-Sac-1332 | Saccharomyces cerevisiae | 29.25 | 9e-09 | 57.0 |
| LLPS-Asg-0731 | Ashbya gossypii | 29.2 | 2e-08 | 56.6 |