LLPS-Dio-0654
Vcl
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | vinculin isoform X2 |
| Gene Name: | Vcl |
| Ensembl Gene: | ENSDORG00000012886.2 |
| Ensembl Protein: | ENSDORP00000012116.2 |
| Organism: | Dipodomys ordii |
| Taxa ID: | 10020 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Centrosome/Spindle pole body, Postsynaptic density | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSDORT00000012886.2 | ENSDORP00000012116.2 |
| Ensembl | ENSDORT00000023949.1 | ENSDORP00000021460.1 |
| UniProt | A0A1S3FWZ4, A0A1S3FWZ4_DIPOR | |
| RefSeq | , XM_013025629.1 | , XP_012881083.1, XP_012881083.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MPVFHTRTIE SILEPVAQQI SHLVIMHEEG EVDGKAIPDL TAPVAAVQAA VSNLVRVGKE 60 61 TVQTTEDQIL KRDMPPAFIK VENACTKLVQ AAQMLQSDPY SVPARDYLID GSRGILSGTS 120 121 DLLLTFDEAE VRKIIRVCKG ILEYLTVAEV VETMEDLVTY TKNLGPGMTK MAKMIDERQQ 180 181 ELTHQEHRVM LVNSMNTVKE LLPVLISAMK IFVTTKNSKN QGIEEALKNR NFTVEKMSAE 240 241 INEIIRVLQL TSWDEDAWAS KDTEAMKRAL ASIDSKLNQA KGWLRDPNAN PGDAGEQAIR 300 301 QILDEAGKVG ELCAGKERRE ILGTCKMLGQ MTDQVADLRA SRGQGASPVA MQKAQQVSQG 360 361 LDVLTAKVEN AARKLEAMTN SKQSIAKKID AAQNWLADPN GGPEGEEQIR GALAEARKIA 420 421 ELCDDPKERD DILRSLGEIA ALTSKLADLR RQGKGDSPEA RALAKQVATA LQNLQSKTNR 480 481 AVANSRPAKA AVHLEGKIEQ AQRWIDNPTV DDRGVGQAAI RGLVAEGHRL ANVMMGPYRQ 540 541 DLLAKCDRVD QLTAQLADLA ARGEGESPQA RALASQLQDS LKDLKAQMQE AMTQEVSDVF 600 601 SDTTTPIKLL AVAATAPPDT PNREEVFDER AANFENHSGR LGATAEKAAA VGTANKSTVE 660 661 GIQASVKTAR ELTPQVVSAA RILLRNPGNQ AAYEHFETMK NQWIDNVEKM TGLVDEAIDT 720 721 KSLLDASEEA IKKDLDKCKV AMANIQPQML VAGATSIARR ANRILLVAKR EVENSEDPKF 780 781 REAVKAASDE LSKTISPMVL DAKAVAGNIS DPGLQKSFLD SGYRILGAVA KVREAFQPQE 840 841 PDFPPPPPDL EQLRLTDELA PPKPPLPEGE VPPPRPPPPE EKDEEFPEQK AGEVINQPMM 900 901 MAARQLHDEA RKWSSKPGVP ATKVGIGVVA EADVADAVGF PVPSDMEDDY EPELLLMPSN 960 961 QPVNQPILAA AQSLHREATK WSSKGNDIIA AAKRMALLMA EMSRLVRGGS GTKRALIQCA 1020 1021 KDIAKASDEV TRLAKEVAKQ CTDKRIRTNL LQVCERIPTI STQLKILSTV KATMLGRTNI 1080 1081 SDEESEQATE MLVHNAQNLM QSVKETVREA EAASIKIRTD AGFTLRWVRK TPWYQ 1135 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGCCGGTGT TTCATACACG CACGATTGAG AGCATCTTGG AGCCGGTGGC GCAGCAGATC 60 61 TCGCACCTGG TGATTATGCA CGAGGAGGGC GAGGTGGACG GCAAAGCCAT TCCTGACCTC 120 121 ACGGCGCCCG TGGCTGCGGT GCAAGCGGCG GTCAGCAACC TAGTCCGGGT TGGAAAAGAG 180 181 ACTGTTCAGA CCACCGAGGA TCAGATTTTG AAGAGAGATA TGCCACCGGC ATTTATTAAG 240 241 GTCGAGAATG CTTGCACCAA GCTTGTTCAG GCAGCACAGA TGCTTCAGTC AGACCCTTAC 300 301 TCAGTGCCTG CTCGAGATTA TCTCATCGAT GGGTCAAGGG GCATCCTCTC TGGCACATCA 360 361 GACCTGCTTC TTACCTTTGA TGAGGCTGAG GTTCGGAAAA TCATTCGTGT TTGCAAAGGC 420 421 ATCTTGGAAT ATCTTACAGT GGCAGAGGTA GTGGAGACTA TGGAAGATTT GGTCACTTAT 480 481 ACAAAGAATC TTGGGCCAGG AATGACTAAG ATGGCCAAGA TGATTGATGA GAGACAGCAG 540 541 GAGCTGACTC ACCAGGAGCA TCGAGTGATG TTGGTGAACT CGATGAATAC TGTGAAAGAG 600 601 TTGCTTCCAG TTCTCATTTC AGCTATGAAG ATTTTTGTAA CAACTAAAAA CTCAAAAAAC 660 661 CAAGGAATAG AAGAAGCTTT GAAAAATCGC AATTTTACTG TAGAAAAGAT GAGTGCTGAA 720 721 ATTAATGAGA TCATTCGTGT CTTACAACTC ACTTCTTGGG ATGAAGATGC CTGGGCCAGC 780 781 AAGGACACTG AAGCCATGAA GAGAGCACTA GCCTCCATAG ACTCTAAACT GAACCAGGCC 840 841 AAAGGTTGGC TTCGGGACCC CAATGCCAAC CCAGGGGATG CTGGTGAGCA AGCCATCAGG 900 901 CAGATCTTAG ATGAAGCTGG CAAAGTTGGC GAACTTTGTG CAGGCAAGGA ACGCAGGGAG 960 961 ATCCTGGGAA CCTGCAAGAT GCTGGGGCAG ATGACTGATC AAGTGGCTGA CCTCCGAGCC 1020 1021 AGTAGAGGAC AAGGAGCCTC ACCTGTGGCC ATGCAGAAAG CCCAGCAGGT ATCTCAAGGA 1080 1081 CTGGATGTGC TCACGGCGAA GGTGGAAAAT GCAGCTCGCA AGCTGGAAGC CATGACGAAC 1140 1141 TCAAAGCAGA GTATTGCGAA GAAGATCGAT GCTGCTCAGA ATTGGCTTGC AGATCCAAAT 1200 1201 GGTGGACCTG AAGGGGAAGA ACAGATTCGA GGGGCTTTGG CTGAAGCTCG GAAAATAGCA 1260 1261 GAATTGTGTG ATGATCCAAA AGAGAGAGAT GACATTCTGC GTTCCCTTGG AGAAATAGCT 1320 1321 GCTCTGACTT CGAAATTAGC AGATTTAAGA AGACAGGGTA AAGGAGATTC CCCAGAGGCT 1380 1381 CGAGCACTGG CCAAACAGGT AGCCACTGCC TTGCAGAACC TGCAGTCCAA AACCAACAGG 1440 1441 GCTGTGGCCA ACAGCAGACC TGCCAAGGCA GCCGTCCACC TGGAGGGCAA GATTGAGCAA 1500 1501 GCTCAGCGGT GGATTGACAA TCCCACAGTG GACGACCGGG GAGTTGGCCA GGCTGCCATC 1560 1561 CGGGGGCTTG TAGCTGAAGG ACATCGTCTG GCTAATGTTA TGATGGGACC TTATCGACAA 1620 1621 GATCTTCTGG CTAAGTGTGA CCGTGTGGAT CAGCTGACAG CTCAGTTGGC TGACCTGGCT 1680 1681 GCCCGAGGGG AAGGGGAGAG TCCTCAGGCC AGAGCACTTG CATCACAGCT TCAAGACTCC 1740 1741 TTAAAGGATC TGAAAGCCCA GATGCAAGAA GCCATGACTC AGGAGGTGTC AGATGTTTTC 1800 1801 AGTGATACCA CGACTCCCAT CAAGCTATTG GCAGTGGCGG CCACTGCCCC TCCTGATACT 1860 1861 CCCAATAGGG AGGAGGTATT TGATGAGAGA GCAGCAAACT TTGAGAACCA TTCAGGAAGG 1920 1921 CTTGGAGCCA CAGCAGAGAA GGCGGCTGCT GTTGGTACTG CTAACAAATC AACAGTGGAA 1980 1981 GGCATTCAGG CGTCAGTGAA GACGGCCCGA GAACTCACAC CCCAGGTTGT ATCTGCTGCT 2040 2041 CGCATCTTAC TTAGGAACCC TGGAAATCAA GCTGCTTATG AACATTTTGA GACTATGAAG 2100 2101 AACCAGTGGA TTGATAATGT TGAAAAAATG ACAGGGCTGG TGGACGAAGC AATTGATACC 2160 2161 AAATCTCTCT TGGATGCTTC TGAAGAAGCA ATTAAAAAGG ACCTGGACAA GTGTAAGGTA 2220 2221 GCTATGGCCA ACATTCAGCC GCAGATGCTG GTCGCTGGAG CAACCAGTAT CGCTCGTCGG 2280 2281 GCCAACCGAA TCCTGCTGGT TGCTAAGAGG GAGGTAGAGA ACTCTGAAGA TCCCAAGTTC 2340 2341 CGTGAGGCTG TCAAAGCCGC CTCTGATGAA CTGAGCAAAA CCATCTCCCC GATGGTGCTG 2400 2401 GATGCAAAGG CTGTGGCTGG AAACATCTCT GACCCTGGCC TGCAAAAGAG CTTCCTGGAC 2460 2461 TCAGGATATC GGATCCTGGG AGCTGTGGCC AAGGTCAGAG AAGCTTTCCA ACCTCAGGAG 2520 2521 CCTGACTTCC CGCCGCCTCC ACCAGACCTT GAACAGCTCC GTCTAACAGA TGAGCTTGCT 2580 2581 CCTCCCAAAC CACCACTGCC TGAGGGTGAG GTCCCTCCAC CCAGGCCCCC ACCTCCAGAG 2640 2641 GAAAAGGATG AAGAGTTCCC TGAGCAGAAA GCCGGGGAGG TGATTAACCA GCCAATGATG 2700 2701 ATGGCTGCCA GGCAGCTCCA TGATGAAGCT CGCAAATGGT CCAGCAAGCC GGGTGTCCCA 2760 2761 GCCACTAAGG TGGGTATAGG AGTTGTAGCT GAGGCAGATG TGGCTGATGC TGTTGGGTTC 2820 2821 CCTGTCCCCT CTGACATGGA AGATGATTAC GAACCTGAGC TGCTGTTAAT GCCATCTAAT 2880 2881 CAGCCAGTCA ACCAGCCCAT TCTGGCCGCG GCTCAGTCCT TGCATCGGGA AGCTACCAAG 2940 2941 TGGTCTAGTA AGGGCAATGA CATCATTGCA GCAGCCAAGC GCATGGCTCT ACTGATGGCT 3000 3001 GAGATGTCTC GGCTTGTGAG AGGGGGCAGT GGTACCAAAC GGGCACTTAT TCAGTGCGCC 3060 3061 AAGGACATCG CCAAGGCCTC AGATGAGGTC ACTCGGTTGG CCAAGGAGGT TGCCAAGCAG 3120 3121 TGCACAGATA AGCGGATTAG AACCAATCTC TTGCAGGTAT GTGAACGAAT CCCAACTATA 3180 3181 AGTACCCAGC TGAAAATCCT GTCCACAGTG AAGGCCACCA TGCTGGGCCG GACCAACATC 3240 3241 AGTGATGAGG AATCTGAACA GGCCACAGAG ATGCTGGTTC ACAATGCCCA GAACCTTATG 3300 3301 CAGTCTGTGA AAGAGACTGT GCGAGAGGCA GAGGCTGCTT CAATCAAAAT CCGAACAGAT 3360 3361 GCTGGATTTA CACTGCGCTG GGTCAGAAAG ACTCCTTGGT ACCAGTAG 3408 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Maf-4007 | Macaca fascicularis | 100.0 | 5e-46 | 166 |
| LLPS-Mum-3804 | Mus musculus | 99.24 | 0.0 | 1664 |
| LLPS-Eqc-2455 | Equus caballus | 99.02 | 0.0 | 1652 |
| LLPS-Sus-4256 | Sus scrofa | 98.86 | 0.0 | 2071 |
| LLPS-Bot-4310 | Bos taurus | 98.77 | 0.0 | 2072 |
| LLPS-Orc-4110 | Oryctolagus cuniculus | 98.77 | 0.0 | 2074 |
| LLPS-Caf-3055 | Canis familiaris | 98.69 | 0.0 | 1651 |
| LLPS-Gog-4538 | Gorilla gorilla | 98.59 | 0.0 | 2073 |
| LLPS-Pap-3303 | Pan paniscus | 98.59 | 0.0 | 2073 |
| LLPS-Pat-4008 | Pan troglodytes | 98.59 | 0.0 | 2073 |
| LLPS-Hos-2296 | Homo sapiens | 98.59 | 0.0 | 2073 |
| LLPS-Ict-0466 | Ictidomys tridecemlineatus | 98.59 | 0.0 | 2070 |
| LLPS-Caj-1079 | Callithrix jacchus | 98.5 | 0.0 | 2071 |
| LLPS-Cea-1446 | Cercocebus atys | 98.41 | 0.0 | 2066 |
| LLPS-Aon-0829 | Aotus nancymaae | 98.41 | 0.0 | 2071 |
| LLPS-Paa-3225 | Papio anubis | 98.41 | 0.0 | 2066 |
| LLPS-Man-0589 | Macaca nemestrina | 98.41 | 0.0 | 2066 |
| LLPS-Mam-4250 | Macaca mulatta | 98.41 | 0.0 | 2066 |
| LLPS-Nol-3649 | Nomascus leucogenys | 98.39 | 0.0 | 1934 |
| LLPS-Loa-1244 | Loxodonta africana | 98.36 | 0.0 | 1646 |
| LLPS-Chs-3363 | Chlorocebus sabaeus | 98.33 | 0.0 | 2063 |
| LLPS-Poa-3838 | Pongo abelii | 98.33 | 0.0 | 2069 |
| LLPS-Fud-3157 | Fukomys damarensis | 98.24 | 0.0 | 2089 |
| LLPS-Ran-3617 | Rattus norvegicus | 98.24 | 0.0 | 2062 |
| LLPS-Mal-1944 | Mandrillus leucophaeus | 98.24 | 0.0 | 2063 |
| LLPS-Cap-4603 | Cavia porcellus | 98.24 | 0.0 | 2062 |
| LLPS-Otg-0585 | Otolemur garnettii | 98.11 | 0.0 | 1919 |
| LLPS-Aim-4192 | Ailuropoda melanoleuca | 98.07 | 0.0 | 2050 |
| LLPS-Ova-0152 | Ovis aries | 98.04 | 0.0 | 1935 |
| LLPS-Mup-1650 | Mustela putorius furo | 97.97 | 0.0 | 2058 |
| LLPS-Urm-0748 | Ursus maritimus | 97.93 | 0.0 | 1654 |
| LLPS-Mod-1452 | Monodelphis domestica | 97.49 | 0.0 | 1638 |
| LLPS-Sah-1974 | Sarcophilus harrisii | 97.45 | 0.0 | 1552 |
| LLPS-Fec-2309 | Felis catus | 97.27 | 0.0 | 2028 |
| LLPS-Rhb-2930 | Rhinopithecus bieti | 96.74 | 0.0 | 2013 |
| LLPS-Mea-3023 | Mesocricetus auratus | 95.42 | 0.0 | 2015 |
| LLPS-Cas-3228 | Carlito syrichta | 95.22 | 0.0 | 1975 |
| LLPS-Myl-3799 | Myotis lucifugus | 94.51 | 0.0 | 1891 |
| LLPS-Fia-3753 | Ficedula albicollis | 93.95 | 0.0 | 1563 |
| LLPS-Gaga-3367 | Gallus gallus | 93.49 | 0.0 | 2001 |
| LLPS-Anp-2786 | Anas platyrhynchos | 93.26 | 0.0 | 1889 |
| LLPS-Anc-3008 | Anolis carolinensis | 92.91 | 0.0 | 1977 |
| LLPS-Meg-1210 | Meleagris gallopavo | 92.63 | 0.0 | 1879 |
| LLPS-Tag-0763 | Taeniopygia guttata | 92.63 | 0.0 | 1931 |
| LLPS-Pes-2863 | Pelodiscus sinensis | 91.97 | 0.0 | 1847 |
| LLPS-Lac-3637 | Latimeria chalumnae | 90.74 | 0.0 | 1443 |
| LLPS-Scf-3460 | Scleropages formosus | 87.8 | 0.0 | 1891 |
| LLPS-Xet-2513 | Xenopus tropicalis | 87.41 | 0.0 | 1873 |
| LLPS-Icp-0472 | Ictalurus punctatus | 86.36 | 0.0 | 1826 |
| LLPS-Asm-1083 | Astyanax mexicanus | 86.18 | 0.0 | 1825 |
| LLPS-Dar-1398 | Danio rerio | 85.48 | 0.0 | 1825 |
| LLPS-Orn-0480 | Oreochromis niloticus | 84.03 | 0.0 | 1768 |
| LLPS-Xim-0886 | Xiphophorus maculatus | 81.6 | 0.0 | 1734 |
| LLPS-Scm-2663 | Scophthalmus maximus | 81.21 | 0.0 | 1719 |
| LLPS-Gaa-3776 | Gasterosteus aculeatus | 81.18 | 0.0 | 1713 |
| LLPS-Orl-0838 | Oryzias latipes | 81.14 | 0.0 | 1724 |
| LLPS-Pof-3832 | Poecilia formosa | 80.64 | 0.0 | 1672 |
| LLPS-Tar-2540 | Takifugu rubripes | 80.3 | 0.0 | 1364 |
| LLPS-Ten-3181 | Tetraodon nigroviridis | 79.79 | 0.0 | 1672 |
| LLPS-Ora-3136 | Ornithorhynchus anatinus | 77.91 | 0.0 | 1348 |
| LLPS-Leo-2910 | Lepisosteus oculatus | 76.22 | 0.0 | 1560 |
| LLPS-Cis-0110 | Ciona savignyi | 69.03 | 1e-48 | 191 |
| LLPS-Cii-1686 | Ciona intestinalis | 68.24 | 2e-55 | 214 |
| LLPS-Drm-2150 | Drosophila melanogaster | 67.01 | 3e-64 | 240 |
| LLPS-Cae-1254 | Caenorhabditis elegans | 61.62 | 9e-59 | 225 |