LLPS-Cii-1686
LOC100185663
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | vinculin |
| Gene Name: | LOC100185663 |
| Ensembl Gene: | ENSCING00000023532.1 |
| Ensembl Protein: | ENSCINP00000036097.1 |
| Organism: | Ciona intestinalis |
| Taxa ID: | 7719 |
| LLPS Type: | Client |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Centrosome/Spindle pole body, Postsynaptic density | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSCINT00000034018.1 | ENSCINP00000036097.1 |
| UniProt | H2Y2G2, H2Y2G2_CIOIN, A0A1W2W9C3 | |
| RefSeq | , XM_002123718.1 | , XP_002123754.1, XP_002123754.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MPVFHTKTIE QILEPVAEQV SHLVILHEQG EDGAAIPSLM KPIQAVSAAV NNLAKVGTAQ 60 61 IQTSKDEVLK LDTPEAINKV KSSADLLLDS AKLIEEDEYS KQGREKLIAG SRGILQGTSD 120 121 LLLIFDEAEV RRICHVCRRV RDYLKVSEVV AGMEDLVTYV KNLTPGMTNL SDLVLQRSKD 180 181 LTNALHADQL KTGVADLRNQ LPNLISSMKI FVTTVDGSGV GSEASVHNRQ YYVKNLSDII 240 241 TEIIRVLQLV STDQEILVDP TNVLQLKQVR DKMANNLIAA NRWLNDPNAP PDTADELALR 300 301 QTLDQAREIG SKAGGALGAK IMDKCNDIGI MTEKLAALRK QNKGNSAEAR RLANQIQTAL 360 361 NGLLQDVDDA LKNLEEIDEA FGVVSSKTPS AKEWLADPQA KPGPGTGSQD IRDIIGATRK 420 421 IAKSLATNPQ TAKDAAELMK MCDELDELME KLDAYRERGE GHLPEARHLA KQAADKIGQI 480 481 NAKIGKALAS GGLPQTLEAK LDVANRWLDH PGVEDGGKGM LAARSVMSDA RKLAVECDNP 540 541 VIKAALLQNA AECESLCNQL ADLVKQGKGG SPEARRIAEE LQQKLQELKQ NMKLAVIGQV 600 601 ADEFSDTTTV LKQFVTAASA PKDVAGREEK FAERSQALTK QAQKLANLGI QAVATSELGA 660 661 EEKVAKATLS AKKIQELTPQ VINAGKIVLD YPENKLAKEH LKALTDEWTE HVDDLTEQVD 720 721 DAMDVVDFIK ASEDGIKKDH KTCMKALQDN QPTVALPAAG NIARRAHRIL MAGKREVENT 780 781 DDAAYVQELK GNLNNLSRTI NPMVQATREY ANNPNSNAAK DNVRECDDQL IAAVAQVRNT 840 841 VEARRIEQQA KNIVIEEEPP PVPPLPQDCE AAPPVPPLPE EEEFPEEQEE DVPMMQAARE 900 901 LHEEARKWES KGNDIIATAK RMALLMAKMS HLVRGEEGRK SDLIACAKEI AKASNEVTRL 960 961 ANEVADKCSD RRIRTDMKKT LDRIPTISTQ LRILSTVKAA SLGDNMDMTK EEEEAAEQAT 1020 1021 EMLVHNAQNL MMSVKDTVRS AEAASIRIRT EAGVMMRWVR KS 1062 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGCCGGTGT TTCACACGAA GACGATTGAA CAGATTTTGG AACCGGTTGC GGAACAAGTG 60 61 TCCCATCTTG TCATCCTTCA CGAACAGGGG GAAGATGGCG CGGCAATTCC TTCTTTGATG 120 121 AAACCGATTC AAGCCGTGAG TGCGGCTGTA AACAACCTTG CAAAAGTTGG GACGGCGCAA 180 181 ATCCAAACAT CTAAGGATGA AGTTCTTAAA CTTGATACAC CGGAGGCGAT CAACAAAGTG 240 241 AAGTCTAGTG CCGACCTTCT GCTTGATTCG GCCAAACTTA TTGAGGAAGA TGAATATTCA 300 301 AAGCAAGGAA GGGAGAAGTT GATAGCTGGG TCGAGGGGAA TCCTCCAAGG AACATCCGAT 360 361 CTTCTTCTCA TCTTTGATGA AGCTGAGGTT CGTCGTATTT GTCATGTTTG CCGCAGAGTT 420 421 CGGGATTATC TTAAAGTATC GGAAGTTGTG GCCGGGATGG AAGACCTTGT TACTTATGTT 480 481 AAAAACCTTA CACCAGGAAT GACAAATCTA TCTGACTTGG TGTTGCAAAG GTCCAAGGAT 540 541 CTCACCAACG CTTTGCATGC CGATCAATTG AAAACTGGAG TTGCAGATTT ACGGAATCAG 600 601 TTGCCCAACT TAATATCAAG TATGAAGATA TTCGTTACAA CTGTAGATGG GAGTGGTGTT 660 661 GGAAGTGAAG CATCTGTTCA CAACAGGCAA TATTACGTCA AGAATCTTTC TGATATTATC 720 721 ACAGAAATAA TTCGTGTTTT ACAACTTGTG TCCACCGATC AGGAGATACT TGTCGACCCA 780 781 ACAAACGTAT TACAGTTGAA ACAAGTCCGA GACAAGATGG CAAACAATCT GATTGCTGCG 840 841 AACCGCTGGC TTAATGATCC TAACGCACCT CCCGACACAG CGGATGAACT CGCCCTTCGA 900 901 CAAACTTTGG ATCAAGCTCG GGAGATCGGG AGCAAAGCTG GTGGGGCGTT GGGAGCAAAG 960 961 ATAATGGACA AGTGCAACGA CATTGGTATT ATGACGGAGA AGCTTGCCGC TCTGCGCAAA 1020 1021 CAAAACAAAG GTAATTCAGC GGAAGCCCGT CGTCTTGCAA ATCAAATTCA AACGGCTTTG 1080 1081 AATGGTTTGT TGCAAGATGT GGATGACGCA TTAAAGAATC TGGAAGAAAT TGATGAAGCA 1140 1141 TTTGGTGTAG TTTCAAGCAA GACGCCTTCT GCTAAGGAAT GGCTGGCTGA TCCTCAAGCT 1200 1201 AAACCAGGAC CTGGTACTGG ATCTCAAGAT ATCAGAGACA TTATTGGGGC AACCAGGAAG 1260 1261 ATAGCAAAGA GTTTGGCTAC CAATCCCCAA ACAGCCAAAG ATGCGGCCGA ACTAATGAAG 1320 1321 ATGTGCGATG AGTTAGATGA GTTGATGGAG AAGTTGGATG CTTACAGGGA GAGAGGGGAA 1380 1381 GGACATCTAC CTGAAGCTAG ACATCTTGCG AAGCAAGCTG CAGATAAGAT TGGGCAAATC 1440 1441 AACGCAAAGA TTGGTAAAGC ACTCGCATCA GGTGGTTTGC CCCAAACACT GGAAGCGAAG 1500 1501 TTGGATGTGG CGAACCGTTG GCTTGACCAC CCTGGTGTAG AGGATGGAGG AAAAGGGATG 1560 1561 CTGGCCGCTA GGAGTGTCAT GAGTGATGCA AGGAAACTGG CTGTGGAATG TGATAATCCT 1620 1621 GTAATCAAAG CAGCTTTGCT ACAAAATGCT GCAGAGTGTG AGAGTTTGTG TAATCAGCTT 1680 1681 GCTGATCTGG TTAAGCAAGG TAAAGGTGGT TCACCTGAAG CGAGAAGAAT CGCCGAAGAA 1740 1741 CTCCAGCAGA AACTACAAGA GTTGAAGCAA AACATGAAGT TGGCGGTGAT CGGTCAAGTT 1800 1801 GCTGATGAGT TTTCAGACAC AACAACCGTG CTCAAGCAAT TCGTAACTGC TGCTTCAGCT 1860 1861 CCTAAGGATG TAGCGGGGCG AGAAGAGAAG TTTGCAGAAA GGTCTCAAGC TCTTACCAAA 1920 1921 CAAGCACAAA AGTTGGCGAA CCTAGGAATA CAAGCTGTGG CAACCAGTGA GCTTGGTGCT 1980 1981 GAGGAAAAAG TGGCAAAAGC TACACTTTCA GCAAAGAAGA TTCAAGAACT TACACCACAA 2040 2041 GTTATTAATG CAGGGAAAAT TGTTCTTGAT TATCCTGAGA ATAAACTTGC CAAGGAACAT 2100 2101 TTGAAAGCTC TCACAGATGA ATGGACGGAA CATGTGGATG ACCTCACTGA GCAAGTGGAT 2160 2161 GACGCGATGG ATGTTGTGGA TTTCATTAAA GCATCAGAAG ATGGGATCAA GAAAGATCAT 2220 2221 AAAACTTGTA TGAAAGCTCT GCAGGATAAC CAACCAACAG TTGCTTTGCC AGCTGCCGGT 2280 2281 AACATTGCAC GCCGAGCTCA TCGTATATTG ATGGCAGGTA AGAGGGAGGT TGAGAATACA 2340 2341 GATGATGCTG CTTATGTGCA AGAGTTGAAA GGTAACTTAA ACAACCTGAG TCGAACCATC 2400 2401 AACCCTATGG TACAAGCTAC TCGTGAATAC GCCAACAATC CAAACTCTAA CGCTGCCAAG 2460 2461 GATAATGTTA GGGAATGTGA TGATCAGTTG ATTGCAGCTG TAGCACAAGT GAGGAACACA 2520 2521 GTGGAAGCGA GAAGGATCGA ACAACAAGCC AAGAATATTG TGATTGAGGA GGAACCTCCA 2580 2581 CCCGTACCTC CCCTGCCACA GGATTGTGAG GCAGCTCCTC CCGTTCCTCC TCTGCCTGAG 2640 2641 GAAGAAGAAT TCCCCGAGGA GCAAGAAGAA GATGTCCCGA TGATGCAAGC GGCTCGTGAG 2700 2701 TTGCATGAGG AGGCAAGAAA GTGGGAGAGC AAAGGAAATG ACATCATTGC GACTGCAAAG 2760 2761 AGAATGGCTC TTCTTATGGC GAAGATGTCG CATCTTGTAA GAGGGGAGGA GGGAAGAAAG 2820 2821 AGTGATCTAA TAGCTTGTGC CAAGGAGATT GCTAAAGCAT CGAATGAAGT AACCAGACTT 2880 2881 GCTAATGAGG TTGCTGATAA ATGCTCTGAT AGAAGGATCC GCACAGACAT GAAGAAAACA 2940 2941 TTAGATCGAA TCCCAACCAT TAGTACACAG CTGCGTATAT TGTCCACTGT CAAAGCTGCT 3000 3001 TCACTTGGTG ATAACATGGA TATGACTAAG GAGGAAGAAG AAGCTGCAGA GCAGGCCACT 3060 3061 GAGATGTTGG TACATAACGC ACAGAACCTC ATGATGAGTG TGAAGGACAC CGTCCGTTCC 3120 3121 GCTGAAGCTG CGTCTATCCG GATCCGCACC GAAGCCGGTG TTATGATGAG ATGGGTACGC 3180 3181 AAGTCATAA 3189 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Cis-0110 | Ciona savignyi | 79.53 | 0.0 | 866 |
| LLPS-Ora-3136 | Ornithorhynchus anatinus | 78.05 | 5e-11 | 71.2 |
| LLPS-Loa-1244 | Loxodonta africana | 70.41 | 1e-57 | 221 |
| LLPS-Mod-1452 | Monodelphis domestica | 70.41 | 1e-57 | 220 |
| LLPS-Urm-0748 | Ursus maritimus | 70.41 | 1e-57 | 220 |
| LLPS-Eqc-2455 | Equus caballus | 70.41 | 3e-57 | 220 |
| LLPS-Sah-1974 | Sarcophilus harrisii | 70.41 | 8e-58 | 221 |
| LLPS-Mum-3804 | Mus musculus | 70.41 | 1e-57 | 221 |
| LLPS-Orl-0838 | Oryzias latipes | 69.82 | 9e-56 | 215 |
| LLPS-Icp-0472 | Ictalurus punctatus | 69.82 | 4e-56 | 216 |
| LLPS-Scf-3460 | Scleropages formosus | 69.82 | 2e-56 | 217 |
| LLPS-Gaa-3776 | Gasterosteus aculeatus | 69.82 | 4e-56 | 216 |
| LLPS-Xim-0886 | Xiphophorus maculatus | 69.82 | 8e-56 | 215 |
| LLPS-Scm-2663 | Scophthalmus maximus | 69.23 | 3e-55 | 213 |
| LLPS-Leo-2910 | Lepisosteus oculatus | 69.23 | 1e-55 | 214 |
| LLPS-Asm-1083 | Astyanax mexicanus | 69.23 | 2e-55 | 214 |
| LLPS-Pof-3832 | Poecilia formosa | 68.64 | 6e-55 | 213 |
| LLPS-Orn-0480 | Oreochromis niloticus | 68.42 | 1e-46 | 186 |
| LLPS-Anp-2786 | Anas platyrhynchos | 68.05 | 2e-54 | 211 |
| LLPS-Man-0589 | Macaca nemestrina | 68.05 | 2e-54 | 211 |
| LLPS-Fec-2309 | Felis catus | 68.05 | 2e-54 | 211 |
| LLPS-Meg-1210 | Meleagris gallopavo | 68.05 | 2e-54 | 211 |
| LLPS-Hos-2296 | Homo sapiens | 68.05 | 2e-54 | 211 |
| LLPS-Pat-4008 | Pan troglodytes | 68.05 | 2e-54 | 211 |
| LLPS-Pap-3303 | Pan paniscus | 68.05 | 2e-54 | 211 |
| LLPS-Orc-4110 | Oryctolagus cuniculus | 68.05 | 2e-54 | 211 |
| LLPS-Fia-3753 | Ficedula albicollis | 68.05 | 2e-54 | 211 |
| LLPS-Pes-2863 | Pelodiscus sinensis | 68.05 | 2e-54 | 211 |
| LLPS-Otg-0585 | Otolemur garnettii | 68.05 | 2e-54 | 211 |
| LLPS-Mam-4250 | Macaca mulatta | 68.05 | 2e-54 | 211 |
| LLPS-Poa-3838 | Pongo abelii | 68.05 | 2e-54 | 211 |
| LLPS-Tag-0763 | Taeniopygia guttata | 68.05 | 2e-54 | 211 |
| LLPS-Anc-3008 | Anolis carolinensis | 68.05 | 2e-54 | 211 |
| LLPS-Nol-3649 | Nomascus leucogenys | 68.05 | 2e-54 | 211 |
| LLPS-Ict-0466 | Ictidomys tridecemlineatus | 68.05 | 2e-54 | 211 |
| LLPS-Gaga-3367 | Gallus gallus | 68.05 | 2e-54 | 211 |
| LLPS-Cas-3228 | Carlito syrichta | 68.05 | 3e-54 | 211 |
| LLPS-Sus-4256 | Sus scrofa | 68.05 | 2e-54 | 211 |
| LLPS-Aon-0829 | Aotus nancymaae | 68.05 | 2e-54 | 211 |
| LLPS-Cea-1446 | Cercocebus atys | 68.05 | 2e-54 | 211 |
| LLPS-Chs-3363 | Chlorocebus sabaeus | 68.05 | 2e-54 | 211 |
| LLPS-Mea-3023 | Mesocricetus auratus | 68.05 | 7e-54 | 209 |
| LLPS-Caj-1079 | Callithrix jacchus | 68.05 | 2e-54 | 211 |
| LLPS-Fud-3157 | Fukomys damarensis | 68.05 | 2e-54 | 211 |
| LLPS-Gog-4538 | Gorilla gorilla | 68.05 | 2e-54 | 211 |
| LLPS-Bot-4310 | Bos taurus | 68.05 | 2e-54 | 211 |
| LLPS-Dio-0654 | Dipodomys ordii | 68.05 | 2e-54 | 211 |
| LLPS-Aim-4192 | Ailuropoda melanoleuca | 68.05 | 2e-54 | 211 |
| LLPS-Mup-1650 | Mustela putorius furo | 68.05 | 2e-54 | 211 |
| LLPS-Myl-3799 | Myotis lucifugus | 68.05 | 1e-54 | 211 |
| LLPS-Ova-0152 | Ovis aries | 68.05 | 2e-54 | 211 |
| LLPS-Mal-1944 | Mandrillus leucophaeus | 68.05 | 2e-54 | 211 |
| LLPS-Paa-3225 | Papio anubis | 68.05 | 2e-54 | 211 |
| LLPS-Ran-3617 | Rattus norvegicus | 68.05 | 3e-54 | 211 |
| LLPS-Caf-3055 | Canis familiaris | 67.86 | 9e-52 | 202 |
| LLPS-Cap-4603 | Cavia porcellus | 67.46 | 8e-54 | 209 |
| LLPS-Xet-2513 | Xenopus tropicalis | 67.46 | 6e-54 | 209 |
| LLPS-Rhb-2930 | Rhinopithecus bieti | 66.86 | 9e-52 | 202 |
| LLPS-Maf-4007 | Macaca fascicularis | 62.5 | 8e-20 | 91.3 |
| LLPS-Ten-3181 | Tetraodon nigroviridis | 60.95 | 3e-46 | 185 |
| LLPS-Drm-2150 | Drosophila melanogaster | 55.88 | 2e-40 | 166 |
| LLPS-Cae-1254 | Caenorhabditis elegans | 54.91 | 3e-43 | 175 |
| LLPS-Tar-2540 | Takifugu rubripes | 38.86 | 6e-161 | 506 |
| LLPS-Lac-3637 | Latimeria chalumnae | 37.85 | 5e-142 | 454 |
| LLPS-Dar-1398 | Danio rerio | 37.71 | 0.0 | 627 |