LLPS-Dar-3371
daw1
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Dynein assembly factor with WDR repeat domains 1; Outer row dynein assembly protein 16 homolog; WD repeat-containing protein 69 |
| Gene Name: | daw1, oda16, wdr69, si:dkey-223n17.5, zgc:153626 |
| Ensembl Gene: | ENSDARG00000021462.11 |
| Ensembl Protein: | ENSDARP00000116595.1 |
| Organism: | Danio rerio |
| Taxa ID: | 7955 |
| LLPS Type: | Client |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Nucleolus | Predicted from orthologs | (View) |
▼ FUNCTION
| Required for axonemal dynein assembly and ciliary motility in ciliated organs, including Kupffer's vesicle, during embryogenesis. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSDART00000142790.2 | ENSDARP00000116595.1 |
| Ensembl | ENSDART00000024202.9 | ENSDARP00000017736.9 |
| UniProt | Q1LV15, DAW1_DANRE, Q05AK4, Q05AM0 | |
| GeneBank | BC124403, BC124455, BX908751 | AAI24456.1, AAI24404.1, CAK05479.1 |
| Entrez | 556760 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MRLKRMHIRY YPPGIFLDYE KGGQLRTKCI DLLNLTPETD VEELVLEIRA AEPLITSSCV 60 61 EQVKLLICKL QEKVSQKDER KFYLFRALQA HILPLTNVAF NKSGSCFITG SYDRTCKIWD 120 121 TASGEELHTL EGHRNVVYAI AFNNPYGDKV ATGSFDKTCK LWSAETGKCF YTFRGHTAEI 180 181 VCLAFNPQST LVATGSMDTT AKLWDVESGE EVSTLAGHFA EIISLCFNTT GDRLVTGSFD 240 241 HTAILWDVPS GRKVHVLSGH RGEISCVQFN WDCSLIATAS LDKSCKVWDA EGGQCLATLL 300 301 GHNDEVLDVC FNYTGQLIAT ASADGTSRVF STDTFQCLCQ LEGHKGEISK VCFNAQGSRV 360 361 LTASVDKTSR VWCVKTGACL QVLEGHSDEI FSCAFNYEGD TIITGNYIHL RNTHEFIR 418 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGAGACTGA AACGGATGCA CATACGGTAC TATCCTCCAG GAATTTTCCT AGACTATGAA 60 61 AAAGGGGGAC AGCTGAGGAC GAAATGCATC GATCTGTTAA ACTTGACTCC AGAGACTGAT 120 121 GTGGAAGAGT TGGTTTTAGA GATTAGAGCA GCTGAGCCTC TCATCACCTC CTCCTGTGTC 180 181 GAGCAGGTGA AACTCCTGAT CTGCAAACTG CAGGAGAAAG TCAGCCAAAA GGATGAGCGC 240 241 AAGTTTTACC TTTTTAGGGC ACTTCAGGCT CACATCTTGC CCCTGACGAA TGTAGCCTTC 300 301 AATAAATCAG GATCTTGCTT TATAACCGGA AGCTATGACA GGACCTGTAA AATATGGGAC 360 361 ACTGCATCCG GAGAGGAGCT GCACACTTTG GAGGGTCACA GGAACGTTGT GTATGCCATC 420 421 GCCTTCAACA ACCCTTACGG AGACAAGGTT GCCACAGGCT CCTTTGACAA GACCTGCAAA 480 481 TTGTGGAGTG CTGAAACAGG AAAGTGTTTC TACACGTTTA GAGGGCACAC GGCAGAAATC 540 541 GTATGCCTGG CCTTTAACCC TCAAAGTACC CTTGTTGCTA CAGGCAGCAT GGACACCACG 600 601 GCTAAATTAT GGGATGTTGA AAGTGGGGAA GAGGTGTCTA CATTGGCAGG TCACTTCGCT 660 661 GAGATCATCT CTCTGTGCTT TAACACAACG GGTGATCGAT TGGTCACGGG GTCATTTGAC 720 721 CACACTGCCA TTTTATGGGA TGTTCCTTCT GGCAGGAAAG TTCACGTTCT CTCAGGTCAC 780 781 CGTGGAGAGA TCAGCTGTGT GCAGTTCAAC TGGGACTGTT CCCTCATCGC CACGGCCTCT 840 841 CTGGATAAAT CCTGCAAGGT GTGGGATGCA GAAGGTGGTC AGTGTTTGGC TACTCTCTTA 900 901 GGTCATAATG ATGAGGTGTT GGATGTGTGT TTTAACTACA CTGGTCAGCT GATTGCTACA 960 961 GCCTCTGCTG ATGGTACATC AAGAGTGTTC AGCACTGACA CGTTTCAGTG TTTATGTCAA 1020 1021 TTAGAAGGCC ATAAAGGAGA GATATCAAAG GTGTGTTTTA ATGCGCAGGG GAGCCGCGTG 1080 1081 TTGACGGCGA GTGTGGACAA AACGTCTCGT GTGTGGTGTG TGAAGACGGG AGCGTGTTTG 1140 1141 CAGGTGCTGG AGGGACATTC GGATGAAATC TTCTCCTGCG CGTTCAACTA TGAGGGAGAC 1200 1201 ACCATCATTA CAGGGAGCAA AGACAACACC TGCAGGATCT GGCACTGA 1248 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Cilium | |
Biological Process | Axonemal dynein complex assembly | |
Biological Process | Cilium assembly | |
Biological Process | Cilium-dependent cell motility | |
Biological Process | Determination of left/right symmetry |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Icp-1994 | Ictalurus punctatus | 82.02 | 0.0 | 717 |
| LLPS-Asm-0731 | Astyanax mexicanus | 80.79 | 0.0 | 688 |
| LLPS-Ora-1337 | Ornithorhynchus anatinus | 79.17 | 1e-121 | 359 |
| LLPS-Leo-2430 | Lepisosteus oculatus | 77.59 | 0.0 | 680 |
| LLPS-Xet-0111 | Xenopus tropicalis | 76.47 | 0.0 | 670 |
| LLPS-Orn-0037 | Oreochromis niloticus | 74.14 | 0.0 | 642 |
| LLPS-Otg-0310 | Otolemur garnettii | 73.58 | 0.0 | 635 |
| LLPS-Caf-1277 | Canis familiaris | 73.4 | 0.0 | 641 |
| LLPS-Bot-2955 | Bos taurus | 73.4 | 0.0 | 641 |
| LLPS-Xim-0183 | Xiphophorus maculatus | 73.4 | 0.0 | 634 |
| LLPS-Scm-2376 | Scophthalmus maximus | 73.39 | 0.0 | 582 |
| LLPS-Pof-1583 | Poecilia formosa | 73.15 | 0.0 | 632 |
| LLPS-Scf-0471 | Scleropages formosus | 73.15 | 0.0 | 637 |
| LLPS-Ova-0950 | Ovis aries | 73.15 | 0.0 | 639 |
| LLPS-Aim-2970 | Ailuropoda melanoleuca | 72.91 | 0.0 | 627 |
| LLPS-Mup-3232 | Mustela putorius furo | 72.66 | 0.0 | 637 |
| LLPS-Hos-1198 | Homo sapiens | 72.41 | 0.0 | 639 |
| LLPS-Pat-3157 | Pan troglodytes | 72.41 | 0.0 | 640 |
| LLPS-Eqc-1400 | Equus caballus | 72.41 | 0.0 | 635 |
| LLPS-Pap-1521 | Pan paniscus | 72.29 | 0.0 | 618 |
| LLPS-Pes-0086 | Pelodiscus sinensis | 72.17 | 0.0 | 632 |
| LLPS-Mam-0774 | Macaca mulatta | 72.17 | 0.0 | 634 |
| LLPS-Poa-2785 | Pongo abelii | 72.17 | 0.0 | 635 |
| LLPS-Sus-4551 | Sus scrofa | 72.17 | 0.0 | 629 |
| LLPS-Aon-2327 | Aotus nancymaae | 72.17 | 0.0 | 633 |
| LLPS-Chs-3144 | Chlorocebus sabaeus | 72.17 | 0.0 | 634 |
| LLPS-Maf-1366 | Macaca fascicularis | 72.17 | 0.0 | 634 |
| LLPS-Mal-4218 | Mandrillus leucophaeus | 72.17 | 0.0 | 633 |
| LLPS-Paa-3434 | Papio anubis | 72.17 | 0.0 | 634 |
| LLPS-Gog-3787 | Gorilla gorilla | 71.92 | 0.0 | 639 |
| LLPS-Ran-0787 | Rattus norvegicus | 71.92 | 0.0 | 639 |
| LLPS-Urm-3554 | Ursus maritimus | 71.83 | 0.0 | 599 |
| LLPS-Mum-4798 | Mus musculus | 71.67 | 0.0 | 638 |
| LLPS-Caj-2855 | Callithrix jacchus | 71.67 | 0.0 | 633 |
| LLPS-Fec-3670 | Felis catus | 71.43 | 0.0 | 633 |
| LLPS-Fia-2988 | Ficedula albicollis | 71.22 | 3e-180 | 514 |
| LLPS-Nol-3668 | Nomascus leucogenys | 71.18 | 0.0 | 623 |
| LLPS-Anc-1312 | Anolis carolinensis | 71.18 | 0.0 | 624 |
| LLPS-Fud-0353 | Fukomys damarensis | 71.18 | 0.0 | 622 |
| LLPS-Ict-0985 | Ictidomys tridecemlineatus | 70.94 | 0.0 | 627 |
| LLPS-Cas-1863 | Carlito syrichta | 70.94 | 0.0 | 622 |
| LLPS-Tag-1516 | Taeniopygia guttata | 70.83 | 0.0 | 612 |
| LLPS-Myl-1164 | Myotis lucifugus | 70.69 | 0.0 | 617 |
| LLPS-Mea-1466 | Mesocricetus auratus | 70.44 | 0.0 | 628 |
| LLPS-Gaga-0689 | Gallus gallus | 70.2 | 0.0 | 617 |
| LLPS-Cap-0759 | Cavia porcellus | 69.7 | 0.0 | 612 |
| LLPS-Anp-3294 | Anas platyrhynchos | 69.65 | 0.0 | 589 |
| LLPS-Dio-4269 | Dipodomys ordii | 68.72 | 0.0 | 609 |
| LLPS-Cea-4298 | Cercocebus atys | 66.58 | 0.0 | 566 |
| LLPS-Man-3640 | Macaca nemestrina | 66.5 | 0.0 | 561 |
| LLPS-Orl-2891 | Oryzias latipes | 65.39 | 0.0 | 545 |
| LLPS-Rhb-2034 | Rhinopithecus bieti | 64.61 | 9e-113 | 339 |
| LLPS-Meg-2221 | Meleagris gallopavo | 64.13 | 0.0 | 537 |
| LLPS-Orc-2983 | Oryctolagus cuniculus | 62.1 | 0.0 | 528 |
| LLPS-Chr-0828 | Chlamydomonas reinhardtii | 48.31 | 1e-127 | 382 |
| LLPS-Sem-1965 | Selaginella moellendorffii | 38.81 | 2e-59 | 201 |
| LLPS-Coc-0846 | Corchorus capsularis | 38.22 | 2e-27 | 115 |
| LLPS-Php-2319 | Physcomitrella patens | 37.75 | 8e-27 | 113 |
| LLPS-Gag-1017 | Gaeumannomyces graminis | 37.54 | 6e-53 | 196 |
| LLPS-Lep-1671 | Leersia perrieri | 37.42 | 9e-26 | 110 |
| LLPS-Gaa-3912 | Gasterosteus aculeatus | 37.17 | 5e-42 | 160 |
| LLPS-Mod-1997 | Monodelphis domestica | 36.4 | 5e-45 | 165 |
| LLPS-Lac-2087 | Latimeria chalumnae | 36.4 | 5e-46 | 167 |
| LLPS-Sah-1670 | Sarcophilus harrisii | 36.4 | 6e-46 | 167 |
| LLPS-Cus-2124 | Cucumis sativus | 36.29 | 9e-18 | 89.4 |
| LLPS-Tar-2694 | Takifugu rubripes | 36.03 | 3e-45 | 166 |
| LLPS-Hea-1495 | Helianthus annuus | 36.02 | 9e-27 | 113 |
| LLPS-Nia-1989 | Nicotiana attenuata | 35.71 | 4e-18 | 90.5 |
| LLPS-Tra-2832 | Triticum aestivum | 35.71 | 1e-22 | 101 |
| LLPS-Hov-1642 | Hordeum vulgare | 35.71 | 1e-22 | 102 |
| LLPS-Cae-1849 | Caenorhabditis elegans | 35.45 | 5e-33 | 134 |
| LLPS-Sol-0570 | Solanum lycopersicum | 35.34 | 6e-19 | 93.2 |
| LLPS-Sot-2109 | Solanum tuberosum | 35.34 | 5e-19 | 93.2 |
| LLPS-Mua-0648 | Musa acuminata | 35.29 | 6e-18 | 89.4 |
| LLPS-Drm-0507 | Drosophila melanogaster | 35.29 | 1e-44 | 164 |
| LLPS-Dos-0652 | Dothistroma septosporum | 35.14 | 3e-12 | 72.0 |
| LLPS-Abg-0038 | Absidia glauca | 35.1 | 5e-26 | 113 |
| LLPS-Orp-0615 | Oryza punctata | 34.77 | 3e-39 | 152 |
| LLPS-Loa-2825 | Loxodonta africana | 34.72 | 1e-44 | 164 |
| LLPS-Phv-2605 | Phaseolus vulgaris | 34.56 | 6e-16 | 84.0 |
| LLPS-Cis-1737 | Ciona savignyi | 34.55 | 5e-48 | 179 |
| LLPS-Ors-1965 | Oryza sativa | 34.38 | 4e-39 | 152 |
| LLPS-Orm-0918 | Oryza meridionalis | 34.38 | 4e-39 | 152 |
| LLPS-Orr-2335 | Oryza rufipogon | 34.38 | 2e-39 | 151 |
| LLPS-Orni-0654 | Oryza nivara | 34.38 | 5e-39 | 151 |
| LLPS-Orgl-1347 | Oryza glumaepatula | 34.38 | 3e-39 | 152 |
| LLPS-Via-1400 | Vigna angularis | 34.27 | 2e-36 | 144 |
| LLPS-Vir-2115 | Vigna radiata | 34.27 | 2e-36 | 145 |
| LLPS-Prp-0598 | Prunus persica | 34.26 | 3e-41 | 158 |
| LLPS-Zyt-1277 | Zymoseptoria tritici | 34.23 | 1e-11 | 69.7 |
| LLPS-Ten-2222 | Tetraodon nigroviridis | 34.16 | 1e-45 | 171 |
| LLPS-Mae-0257 | Manihot esculenta | 34.04 | 2e-17 | 88.2 |
| LLPS-Viv-0575 | Vitis vinifera | 34.01 | 1e-39 | 154 |
| LLPS-Sob-1435 | Sorghum bicolor | 33.98 | 7e-38 | 148 |
| LLPS-Art-2856 | Arabidopsis thaliana | 33.82 | 2e-39 | 149 |
| LLPS-Orbr-0586 | Oryza brachyantha | 33.59 | 9e-38 | 147 |
| LLPS-Cii-0493 | Ciona intestinalis | 33.57 | 1e-40 | 154 |
| LLPS-Arl-0934 | Arabidopsis lyrata | 33.45 | 2e-39 | 149 |
| LLPS-Trv-1582 | Trichoderma virens | 33.33 | 3e-57 | 197 |
| LLPS-Glm-1971 | Glycine max | 33.33 | 9e-36 | 142 |
| LLPS-Thc-0178 | Theobroma cacao | 33.33 | 4e-40 | 151 |
| LLPS-Brd-1546 | Brachypodium distachyon | 33.2 | 6e-37 | 145 |
| LLPS-Sei-2106 | Setaria italica | 33.2 | 1e-38 | 150 |
| LLPS-Gor-2545 | Gossypium raimondii | 32.85 | 3e-40 | 151 |
| LLPS-Amt-1259 | Amborella trichopoda | 32.54 | 3e-15 | 81.6 |
| LLPS-Asfu-1327 | Aspergillus fumigatus | 32.22 | 2e-17 | 89.4 |
| LLPS-Chc-0712 | Chondrus crispus | 32.21 | 6e-28 | 121 |
| LLPS-Trr-0795 | Trichoderma reesei | 30.34 | 1e-37 | 147 |
| LLPS-Fus-0344 | Fusarium solani | 29.91 | 8e-36 | 142 |
| LLPS-Asc-0951 | Aspergillus clavatus | 29.43 | 1e-39 | 153 |
| LLPS-Asn-0684 | Aspergillus nidulans | 29.43 | 3e-40 | 155 |
| LLPS-Nef-0511 | Neosartorya fischeri | 29.14 | 1e-39 | 153 |
| LLPS-Tut-2058 | Tursiops truncatus | 28.93 | 5e-39 | 150 |
| LLPS-Fuo-1383 | Fusarium oxysporum | 28.77 | 9e-38 | 148 |
| LLPS-Fuv-0634 | Fusarium verticillioides | 28.77 | 7e-38 | 148 |
| LLPS-Ast-0961 | Aspergillus terreus | 28.57 | 3e-39 | 152 |