• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Cym-0496
CYME_CMK289C

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Proteasome subunit beta
Gene Name: CYME_CMK289C
Ensembl Gene: CMK289C
Ensembl Protein: CMK289CT
Organism: Cyanidioschyzon merolae
Taxa ID: 280699
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, P-bodyPredicted from orthologs(View)

▼ FUNCTION

The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblCMK289CTCMK289CT
UniProtM1VD46, M1VD46_CYAM1
GeneBankAP006493BAM80627.1
RefSeqXM_005536606.1XP_005536663.1

▼ SEQUENCE

Protein Sequence (FASTA)
1     MLLEQDFQGF  SFDLFLRNQQ  LLRRWSNESK  ERIENVLAKP  PRKTGTTIAG  VLFAGGVVLG  60
61    ADTRATEGNV  VADKNCSKIH  YIASNIYCCG  AGTAADTEAT  TQLIASQMEL  HRQAVDRDLV  120
121   PVAAAMTRLK  HYLFRYQGYI  SAALVLGGVD  ELNGPSLYTV  YPHGSVDQLP  YVSMGSGSLA  180
181   AMAVFEARWH  EALTEEEAKC  LVYEAISAGI  ENDLGSGSNV  DLCVVKNGGR  AVDYLRGYAK  240
241   ENVRVYRKPT  GHVFARGTTA  VLAQELRKYV  QVTRVVSDL  279
Nucleotide CDS Sequence (FASTA)
1     ATGCTTCTCG  AGCAGGACTT  CCAGGGATTT  AGTTTTGACT  TGTTTCTGCG  CAACCAGCAG  60
61    CTTTTAAGAC  GCTGGTCTAA  CGAATCCAAG  GAGAGGATCG  AAAACGTCCT  GGCAAAGCCG  120
121   CCACGCAAAA  CCGGGACGAC  CATTGCTGGC  GTACTCTTCG  CTGGCGGTGT  CGTGCTCGGA  180
181   GCAGACACGC  GCGCGACGGA  AGGAAACGTT  GTGGCTGATA  AAAACTGCAG  CAAGATTCAC  240
241   TACATAGCAT  CAAATATTTA  CTGCTGTGGA  GCTGGAACGG  CTGCGGACAC  GGAAGCCACG  300
301   ACGCAGTTGA  TCGCGAGCCA  AATGGAGCTG  CACCGGCAGG  CCGTCGATCG  CGACTTGGTT  360
361   CCGGTGGCCG  CTGCAATGAC  GAGATTAAAA  CACTACTTAT  TTCGCTACCA  AGGATACATA  420
421   TCCGCGGCGC  TTGTTCTAGG  TGGAGTTGAC  GAGCTGAATG  GCCCTTCGCT  GTACACGGTA  480
481   TACCCGCACG  GAAGCGTTGA  CCAGTTGCCC  TATGTATCAA  TGGGTAGTGG  CTCGCTAGCG  540
541   GCAATGGCTG  TGTTTGAAGC  GCGTTGGCAT  GAAGCGCTCA  CTGAAGAAGA  GGCAAAATGT  600
601   CTTGTATACG  AAGCGATCTC  GGCGGGAATC  GAGAACGACC  TGGGCTCCGG  TTCTAATGTT  660
661   GACCTGTGTG  TCGTGAAGAA  CGGTGGCAGG  GCAGTCGATT  ACCTGCGGGG  CTATGCGAAG  720
721   GAAAACGTTC  GTGTTTACCG  AAAACCTACA  GGGCACGTGT  TCGCGCGTGG  CACGACAGCT  780
781   GTCCTTGCAC  AAGAGCTGCG  CAAATACGTT  CAAGTAACGC  GCGTCGTCTC  CGATTTG  837

▼ KEYWORD

ID
Family
Complete proteome
Cytoplasm
Hydrolase
Nucleus
Protease
Proteasome
Reference proteome
Threonine protease

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Cytoplasm
Cellular Component
Nucleus
Cellular Component
Proteasome core complex
Molecular Function
Threonine-type endopeptidase activity
Biological Process
Proteolysis involved in cellular protein catabolic process

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Asm-0699Astyanax mexicanus66.072e-74 235
LLPS-Anc-1575Anolis carolinensis66.041e-42 149
LLPS-Pes-2599Pelodiscus sinensis63.111e-70 226
LLPS-Chc-0417Chondrus crispus62.798e-84 259
LLPS-Fia-1630Ficedula albicollis61.92e-67 216
LLPS-Ran-1942Rattus norvegicus61.512e-71 228
LLPS-Anp-2870Anas platyrhynchos61.461e-67 216
LLPS-Icp-2373Ictalurus punctatus61.361e-78 248
LLPS-Gas-0193Galdieria sulphuraria60.742e-86 266
LLPS-Leo-3685Lepisosteus oculatus60.471e-77 244
LLPS-Gaga-3399Gallus gallus60.477e-75 236
LLPS-Xim-3587Xiphophorus maculatus60.156e-74 235
LLPS-Orl-2027Oryzias latipes60.01e-75 239
LLPS-Orn-2952Oreochromis niloticus59.772e-74 236
LLPS-Tag-3362Taeniopygia guttata59.79e-74 233
LLPS-Gaa-1820Gasterosteus aculeatus59.621e-74 236
LLPS-Abg-0798Absidia glauca59.181e-82 256
LLPS-Mal-2564Mandrillus leucophaeus59.04e-73 233
LLPS-Paa-3846Papio anubis59.04e-73 233
LLPS-Gog-1054Gorilla gorilla59.05e-74 234
LLPS-Cea-3330Cercocebus atys59.08e-74 234
LLPS-Maf-1547Macaca fascicularis59.04e-73 233
LLPS-Nol-0825Nomascus leucogenys59.07e-74 234
LLPS-Poa-0985Pongo abelii59.07e-74 234
LLPS-Man-0816Macaca nemestrina59.08e-74 234
LLPS-Pat-0733Pan troglodytes59.07e-74 234
LLPS-Pap-0938Pan paniscus59.07e-74 234
LLPS-Caj-1572Callithrix jacchus58.944e-74 234
LLPS-Aon-4760Aotus nancymaae58.944e-74 234
LLPS-Scf-3847Scleropages formosus58.878e-74 234
LLPS-Xet-3077Xenopus tropicalis58.781e-75 238
LLPS-Mod-3816Monodelphis domestica58.782e-73 233
LLPS-Chs-4505Chlorocebus sabaeus58.621e-73 233
LLPS-Mum-4882Mus musculus58.621e-73 233
LLPS-Rhb-2544Rhinopithecus bieti58.626e-73 231
LLPS-Hos-4613Homo sapiens58.621e-73 234
LLPS-Dio-2772Dipodomys ordii58.581e-74 236
LLPS-Sah-2518Sarcophilus harrisii58.176e-74 234
LLPS-Eqc-3009Equus caballus58.179e-74 234
LLPS-Otg-2676Otolemur garnettii58.172e-73 233
LLPS-Scm-3646Scophthalmus maximus58.157e-75 237
LLPS-Myl-3012Myotis lucifugus58.114e-73 232
LLPS-Brd-2473Brachypodium distachyon57.921e-76 241
LLPS-Ova-4144Ovis aries57.842e-74 235
LLPS-Ict-0809Ictidomys tridecemlineatus57.841e-73 233
LLPS-Caf-3627Canis familiaris57.848e-74 234
LLPS-Mea-3734Mesocricetus auratus57.782e-74 236
LLPS-Cas-1596Carlito syrichta57.725e-75 237
LLPS-Tar-2914Takifugu rubripes57.691e-70 226
LLPS-Zem-0533Zea mays57.624e-78 244
LLPS-Dar-1713Danio rerio57.524e-72 230
LLPS-Tra-3050Triticum aestivum57.472e-76 240
LLPS-Aim-0609Ailuropoda melanoleuca57.462e-74 235
LLPS-Bot-2648Bos taurus57.462e-74 235
LLPS-Fud-3644Fukomys damarensis57.468e-74 234
LLPS-Sus-0242Sus scrofa57.463e-74 235
LLPS-Cap-1710Cavia porcellus57.467e-74 234
LLPS-Fec-1253Felis catus57.464e-74 234
LLPS-Urm-0666Ursus maritimus57.462e-73 234
LLPS-Sob-1237Sorghum bicolor57.255e-78 244
LLPS-Mup-1759Mustela putorius furo57.096e-74 234
LLPS-Tut-1503Tursiops truncatus57.042e-73 233
LLPS-Loa-2007Loxodonta africana57.031e-73 234
LLPS-Mua-2204Musa acuminata56.981e-76 241
LLPS-Hov-1711Hordeum vulgare56.873e-75 239
LLPS-Php-2134Physcomitrella patens56.517e-77 241
LLPS-Orbr-0831Oryza brachyantha56.462e-75 238
LLPS-Sot-0109Solanum tuberosum56.342e-65 214
LLPS-Coc-1009Corchorus capsularis56.22e-75 238
LLPS-Orgl-0008Oryza glumaepatula55.563e-74 235
LLPS-Orni-1175Oryza nivara55.563e-74 235
LLPS-Ori-0814Oryza indica55.563e-74 235
LLPS-Orb-0211Oryza barthii55.563e-74 235
LLPS-Org-1249Oryza glaberrima55.563e-74 235
LLPS-Orm-1836Oryza meridionalis55.563e-74 235
LLPS-Orr-1126Oryza rufipogon55.563e-74 235
LLPS-Ors-0747Oryza sativa55.563e-74 235
LLPS-Vir-0446Vigna radiata55.261e-73 233
LLPS-Viv-0772Vitis vinifera55.267e-76 239
LLPS-Gor-0817Gossypium raimondii55.221e-77 244
LLPS-Cii-1744Ciona intestinalis55.212e-69 222
LLPS-Orp-0996Oryza punctata55.191e-74 236
LLPS-Sei-1774Setaria italica55.068e-74 236
LLPS-Mae-1703Manihot esculenta55.041e-73 233
LLPS-Arl-2330Arabidopsis lyrata55.025e-76 239
LLPS-Lep-0799Leersia perrieri55.023e-73 232
LLPS-Ere-0092Erinaceus europaeus54.867e-2499.8
LLPS-Cus-1817Cucumis sativus54.859e-74 234
LLPS-Thc-1696Theobroma cacao54.852e-77 243
LLPS-Sem-0696Selaginella moellendorffii54.854e-72 229
LLPS-Glm-0921Glycine max54.851e-73 233
LLPS-Hea-2006Helianthus annuus54.819e-75 236
LLPS-Orc-0120Oryctolagus cuniculus54.728e-62 204
LLPS-Brn-1479Brassica napus54.653e-75 237
LLPS-Brr-0181Brassica rapa54.653e-75 237
LLPS-Art-1536Arabidopsis thaliana54.651e-75 238
LLPS-Spr-1382Sporisorium reilianum54.317e-66 214
LLPS-Usm-1232Ustilago maydis54.315e-67 217
LLPS-Blg-1128Blumeria graminis54.242e-61 202
LLPS-Miv-0693Microbotryum violaceum54.23e-63 207
LLPS-Dac-1575Daucus carota54.11e-73 233
LLPS-Phv-1452Phaseolus vulgaris54.12e-72 230
LLPS-Amt-1619Amborella trichopoda54.14e-77 242
LLPS-Bro-1335Brassica oleracea54.049e-76 239
LLPS-Nia-0448Nicotiana attenuata53.934e-71 227
LLPS-Pot-0416Populus trichocarpa53.91e-73 233
LLPS-Sol-1327Solanum lycopersicum53.561e-71 228
LLPS-Prp-2070Prunus persica53.521e-71 228
LLPS-Met-1989Medicago truncatula52.792e-73 233
LLPS-Put-0398Puccinia triticina52.711e-68 221
LLPS-Mam-4073Macaca mulatta52.486e-28 110
LLPS-Lac-2137Latimeria chalumnae52.431e-64 210
LLPS-Kop-1259Komagataella pastoris52.422e-61 202
LLPS-Drm-1480Drosophila melanogaster52.241e-73 233
LLPS-Scc-1073Schizosaccharomyces cryophilus52.082e-62 204
LLPS-Asfu-0592Aspergillus fumigatus51.991e-62 205
LLPS-Asf-1227Aspergillus flavus51.971e-63 207
LLPS-Aso-0065Aspergillus oryzae51.971e-63 207
LLPS-Scs-0317Sclerotinia sclerotiorum51.821e-62 205
LLPS-Ora-0650Ornithorhynchus anatinus51.692e-52 179
LLPS-Tum-1537Tuber melanosporum51.667e-61 201
LLPS-Nef-1258Neosartorya fischeri51.624e-62 204
LLPS-Pug-0908Puccinia graminis51.625e-69 222
LLPS-Sac-1530Saccharomyces cerevisiae51.543e-58 193
LLPS-Nec-1497Neurospora crassa51.483e-61 202
LLPS-Chr-1111Chlamydomonas reinhardtii51.476e-66 213
LLPS-Asn-0197Aspergillus nidulans51.453e-63 206
LLPS-Scj-0668Schizosaccharomyces japonicus51.322e-62 204
LLPS-Asc-0556Aspergillus clavatus51.251e-62 205
LLPS-Mel-1532Melampsora laricipopulina51.142e-61 202
LLPS-Cog-1283Colletotrichum gloeosporioides51.114e-60 198
LLPS-Fus-1034Fusarium solani51.17e-60 198
LLPS-Asg-0129Ashbya gossypii50.973e-51 175
LLPS-Pyt-1257Pyrenophora teres50.553e-57 191
LLPS-Coo-0858Colletotrichum orbiculare50.371e-59 197
LLPS-Cogr-1415Colletotrichum graminicola50.373e-60 199
LLPS-Ved-0669Verticillium dahliae50.362e-59 196
LLPS-Mao-1010Magnaporthe oryzae50.182e-59 197
LLPS-Scp-1542Schizosaccharomyces pombe50.08e-59 195
LLPS-Map-1320Magnaporthe poae50.03e-58 194
LLPS-Crn-0719Cryptococcus neoformans50.07e-61 201
LLPS-Gag-0688Gaeumannomyces graminis50.04e-59 196
LLPS-Fuv-1207Fusarium verticillioides50.08e-58 192
LLPS-Fuo-0655Fusarium oxysporum50.03e-58 194
LLPS-Dos-1186Dothistroma septosporum49.821e-57 192
LLPS-Phn-1568Phaeosphaeria nodorum49.646e-57 190
LLPS-Ast-1578Aspergillus terreus49.642e-59 197
LLPS-Zyt-1359Zymoseptoria tritici49.631e-58 195
LLPS-Beb-1344Beauveria bassiana49.636e-58 193
LLPS-Yal-0961Yarrowia lipolytica49.628e-57 189
LLPS-Asni-1560Aspergillus niger49.461e-59 197
LLPS-Pytr-0638Pyrenophora triticirepentis49.443e-56 187
LLPS-Tru-1100Triticum urartu49.432e-59 195
LLPS-Trv-0726Trichoderma virens48.92e-55 186
LLPS-Trr-0121Trichoderma reesei48.531e-54 184
LLPS-Ten-3698Tetraodon nigroviridis48.53e-50 172
LLPS-Lem-0465Leptosphaeria maculans48.015e-56 188
LLPS-Pof-4026Poecilia formosa47.377e-50 172
LLPS-Cae-0049Caenorhabditis elegans36.337e-32 124
LLPS-Via-1023Vigna angularis33.334e-1679.0