• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Cym-0107
CYME_CMS034C

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: FACT complex subunit SSRP1
Gene Name: CYME_CMS034C
Ensembl Gene: CMS034C
Ensembl Protein: CMS034CT
Organism: Cyanidioschyzon merolae
Taxa ID: 280699
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Chromatin, Nucleolus, Stress granulePredicted from orthologs(View)

▼ FUNCTION

Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblCMS034CTCMS034CT
UniProtM1VLQ6, M1VLQ6_CYAM1
GeneBankAP006501BAM82683.1
RefSeqXM_005538662.1XP_005538719.1

▼ SEQUENCE

Protein Sequence (FASTA)
1     MSAAQVIDPV  YVTDQSLGPG  SLRLSKAGLL  WSPRNEGLYT  ISVAREDLAS  LRWFRGARGD  60
61    QLRCTRKDGS  TVNFEGFRPA  DRATLEEYVK  EAWAWTKGVP  RGEQGVVGWN  FGQVRIEGES  120
121   VLFVSGSETA  FELPISDISQ  VVRSGRNELA  LEFHLDDTAG  KTDECLVEMR  FQAPTEEDAI  180
181   ALHAELSARV  GSASFMGESL  VFFEELPFIV  PRGRYDLELF  PTYLSMHGKS  FDYKILYKTV  240
241   RRMFLLPKPD  EIHLALVISL  DPPIRQGNTT  YPHLVLQLRR  DDDEIEVALN  MKPEELQKRY  300
301   GDKLPPKISG  ELWQVVTKVL  RVLVDKPLHA  PKNFVTSQGA  HALRTALGAN  DGYLYPLENC  360
361   FFFVNKPPTY  LRYEDVDFVE  FKRLEMDRRF  DLQVVMLNGS  TLLFTNLERS  EFSTLYQFLE  420
421   SKQVRMVGIP  PALLRGATTG  KTSMRAAAVR  AEMAIAAEEA  ARREADGEDD  EEADDQDTKY  480
481   DGKRDPQTFD  DEDDEEDEDF  AGDVEDESDG  APSDSDAARD  DDDDDDDDDD  DDDDEALEAE  540
541   LEPEEPLEQV  TEEDQSQGDP  ESTSAAAAAE  TGHATDLEKA  LHS  583
Nucleotide CDS Sequence (FASTA)
1     ATGAGTGCTG  CCCAGGTCAT  TGATCCCGTT  TATGTGACCG  ACCAGTCGCT  TGGACCTGGG  60
61    TCACTGCGGC  TGTCGAAGGC  TGGACTACTC  TGGTCACCGC  GCAACGAAGG  TCTATACACG  120
121   ATCAGTGTGG  CTCGCGAGGA  CCTCGCGTCG  CTGCGCTGGT  TCAGAGGCGC  TCGCGGTGAC  180
181   CAGCTACGCT  GCACTCGTAA  AGACGGCAGC  ACCGTGAACT  TTGAAGGTTT  TCGTCCAGCG  240
241   GATCGCGCAA  CCTTGGAGGA  GTATGTGAAG  GAGGCCTGGG  CATGGACCAA  GGGTGTACCG  300
301   CGCGGCGAAC  AGGGCGTCGT  CGGATGGAAC  TTTGGACAGG  TGCGCATCGA  GGGTGAGAGC  360
361   GTGCTCTTCG  TCTCTGGATC  AGAGACGGCG  TTCGAGTTGC  CAATTTCGGA  TATATCGCAA  420
421   GTGGTGCGTT  CAGGTCGCAA  CGAGCTGGCG  TTGGAGTTTC  ATCTCGACGA  CACGGCAGGG  480
481   AAAACCGACG  AGTGCCTTGT  TGAGATGCGC  TTCCAGGCAC  CGACCGAGGA  GGACGCAATC  540
541   GCGCTCCACG  CAGAGCTATC  GGCGCGTGTT  GGCTCAGCGT  CGTTTATGGG  TGAGTCTCTA  600
601   GTTTTCTTCG  AGGAACTCCC  GTTTATCGTG  CCGCGAGGTC  GCTACGATCT  CGAGCTGTTC  660
661   CCCACGTACC  TGAGTATGCA  CGGCAAATCT  TTCGACTACA  AGATCCTGTA  CAAGACAGTG  720
721   CGGCGTATGT  TCCTGCTGCC  AAAACCGGAT  GAGATCCATC  TGGCGCTGGT  TATCTCTCTG  780
781   GACCCGCCGA  TTCGCCAGGG  CAACACAACC  TATCCACACC  TGGTGCTCCA  GCTCCGCCGC  840
841   GACGACGATG  AGATCGAGGT  GGCGTTAAAC  ATGAAGCCAG  AAGAGTTGCA  GAAACGCTAC  900
901   GGGGATAAGT  TGCCGCCGAA  AATCAGCGGT  GAGCTCTGGC  AAGTCGTCAC  GAAGGTGCTG  960
961   CGTGTTTTGG  TCGACAAGCC  CCTGCATGCA  CCGAAGAATT  TTGTGACCTC  ACAGGGTGCC  1020
1021  CATGCGCTGC  GCACCGCGCT  CGGTGCCAAT  GACGGTTATC  TGTATCCGCT  GGAGAACTGT  1080
1081  TTCTTCTTTG  TGAACAAGCC  GCCGACCTAT  TTGCGTTATG  AGGATGTTGA  TTTTGTTGAA  1140
1141  TTCAAACGAC  TGGAAATGGA  TAGAAGGTTT  GACCTGCAGG  TCGTGATGCT  GAATGGCTCC  1200
1201  ACGCTGCTCT  TTACGAATCT  CGAGCGAAGC  GAGTTCTCGA  CACTCTACCA  GTTTCTGGAG  1260
1261  AGCAAACAAG  TTCGGATGGT  CGGGATCCCG  CCGGCGCTCC  TGCGCGGTGC  AACGACCGGC  1320
1321  AAGACCAGTA  TGCGCGCGGC  AGCCGTGCGA  GCCGAAATGG  CTATCGCCGC  AGAGGAGGCT  1380
1381  GCTCGTCGTG  AAGCGGATGG  TGAGGACGAC  GAAGAAGCCG  ACGACCAGGA  TACCAAATAT  1440
1441  GATGGGAAAC  GTGATCCGCA  GACGTTTGAC  GACGAGGATG  ACGAGGAAGA  TGAAGATTTT  1500
1501  GCAGGCGACG  TTGAAGATGA  GTCCGACGGT  GCACCCAGTG  ACTCGGATGC  AGCGCGCGAC  1560
1561  GATGACGATG  ATGATGACGA  TGATGATGAT  GATGATGATG  ATGAGGCGCT  AGAAGCCGAA  1620
1621  CTCGAGCCCG  AGGAGCCCCT  CGAGCAAGTC  ACGGAGGAAG  ATCAGTCGCA  AGGCGATCCG  1680
1681  GAATCGACAT  CAGCAGCAGC  AGCAGCAGAG  ACTGGGCATG  CAACTGACCT  GGAAAAAGCT  1740
1741  TTACATTCC  1749

▼ KEYWORD

ID
Family
Chromosome
Complete proteome
DNA damage
DNA repair
DNA replication
Elongation factor
Nucleus
Protein biosynthesis
Reference proteome
Transcription
Transcription regulation

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Chromosome
Cellular Component
Nucleus
Molecular Function
DNA binding
Molecular Function
Translation elongation factor activity
Biological Process
DNA repair
Biological Process
DNA replication

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Gas-0857Galdieria sulphuraria48.484e-139 421
LLPS-Chc-0007Chondrus crispus44.12e-114 357
LLPS-Xet-1628Xenopus tropicalis37.975e-82 275
LLPS-Leo-1578Lepisosteus oculatus37.81e-70 246
LLPS-Scs-0054Sclerotinia sclerotiorum37.385e-44 164
LLPS-Brr-0203Brassica rapa36.281e-83 281
LLPS-Chr-0479Chlamydomonas reinhardtii36.212e-76 262
LLPS-Fud-0019Fukomys damarensis36.218e-85 285
LLPS-Gaga-2726Gallus gallus36.212e-86 289
LLPS-Meg-1460Meleagris gallopavo36.212e-86 289
LLPS-Fia-2029Ficedula albicollis36.211e-86 290
LLPS-Ved-0403Verticillium dahliae36.122e-46 171
LLPS-Brn-0152Brassica napus36.052e-83 280
LLPS-Bro-0151Brassica oleracea36.059e-84 281
LLPS-Cap-1390Cavia porcellus35.974e-85 286
LLPS-Pes-0887Pelodiscus sinensis35.975e-86 288
LLPS-Xim-0114Xiphophorus maculatus35.954e-81 276
LLPS-Drm-0841Drosophila melanogaster35.951e-79 271
LLPS-Eqc-0598Equus caballus35.842e-83 282
LLPS-Mae-0260Manihot esculenta35.81e-61 219
LLPS-Dio-1290Dipodomys ordii35.731e-84 285
LLPS-Bot-0023Bos taurus35.731e-84 285
LLPS-Hov-0009Hordeum vulgare35.734e-79 269
LLPS-Ran-1768Rattus norvegicus35.739e-85 285
LLPS-Mal-1910Mandrillus leucophaeus35.738e-85 285
LLPS-Paa-1244Papio anubis35.731e-84 285
LLPS-Myl-0706Myotis lucifugus35.738e-85 285
LLPS-Mup-0721Mustela putorius furo35.737e-85 285
LLPS-Aim-0287Ailuropoda melanoleuca35.738e-85 285
LLPS-Mum-0192Mus musculus35.731e-84 285
LLPS-Maf-2870Macaca fascicularis35.738e-85 285
LLPS-Mea-0010Mesocricetus auratus35.737e-85 285
LLPS-Chs-0716Chlorocebus sabaeus35.731e-84 285
LLPS-Sus-1554Sus scrofa35.731e-84 285
LLPS-Cea-1208Cercocebus atys35.738e-85 285
LLPS-Aon-1132Aotus nancymaae35.738e-85 285
LLPS-Gog-0664Gorilla gorilla35.738e-85 285
LLPS-Caj-0071Callithrix jacchus35.738e-85 285
LLPS-Caf-0718Canis familiaris35.735e-85 286
LLPS-Poa-0279Pongo abelii35.738e-85 285
LLPS-Mam-0799Macaca mulatta35.738e-85 285
LLPS-Cas-0721Carlito syrichta35.737e-85 285
LLPS-Nol-0537Nomascus leucogenys35.739e-85 285
LLPS-Anc-0353Anolis carolinensis35.734e-84 283
LLPS-Ict-2968Ictidomys tridecemlineatus35.738e-85 285
LLPS-Hos-1608Homo sapiens35.738e-85 285
LLPS-Urm-1214Ursus maritimus35.737e-85 285
LLPS-Pap-0137Pan paniscus35.732e-83 284
LLPS-Pat-0005Pan troglodytes35.738e-85 285
LLPS-Fec-0093Felis catus35.738e-85 285
LLPS-Man-0186Macaca nemestrina35.738e-85 285
LLPS-Loa-0373Loxodonta africana35.731e-84 285
LLPS-Rhb-0123Rhinopithecus bieti35.738e-85 285
LLPS-Pof-0177Poecilia formosa35.712e-80 274
LLPS-Anp-0597Anas platyrhynchos35.592e-82 278
LLPS-Art-0094Arabidopsis thaliana35.551e-82 278
LLPS-Sah-0639Sarcophilus harrisii35.496e-84 283
LLPS-Otg-1364Otolemur garnettii35.495e-84 283
LLPS-Tar-1677Takifugu rubripes35.483e-79 270
LLPS-Ten-0235Tetraodon nigroviridis35.483e-80 273
LLPS-Orgl-0610Oryza glumaepatula35.447e-82 276
LLPS-Lep-0568Leersia perrieri35.442e-81 275
LLPS-Orb-0106Oryza barthii35.447e-82 276
LLPS-Ori-0543Oryza indica35.447e-82 276
LLPS-Orni-0450Oryza nivara35.447e-82 276
LLPS-Orm-0977Oryza meridionalis35.447e-82 276
LLPS-Org-0002Oryza glaberrima35.447e-82 276
LLPS-Ors-0229Oryza sativa35.447e-82 276
LLPS-Coc-0041Corchorus capsularis35.361e-80 273
LLPS-Tra-0830Triticum aestivum35.353e-75 258
LLPS-Sem-0420Selaginella moellendorffii35.353e-75 258
LLPS-Sei-0397Setaria italica35.278e-78 265
LLPS-Brd-0806Brachypodium distachyon35.273e-78 266
LLPS-Vir-0344Vigna radiata35.218e-80 271
LLPS-Met-1959Medicago truncatula35.27e-82 276
LLPS-Mod-0502Monodelphis domestica35.26e-84 283
LLPS-Osl-0107Ostreococcus lucimarinus35.163e-66 233
LLPS-Scf-0084Scleropages formosus35.023e-78 270
LLPS-Scm-2718Scophthalmus maximus35.06e-80 272
LLPS-Orn-0815Oreochromis niloticus35.09e-80 271
LLPS-Orp-1228Oryza punctata34.999e-81 273
LLPS-Orbr-0551Oryza brachyantha34.992e-81 275
LLPS-Dar-0845Danio rerio34.931e-80 274
LLPS-Scp-0628Schizosaccharomyces pombe34.892e-79 266
LLPS-Orr-1426Oryza rufipogon34.883e-79 270
LLPS-Tru-0033Triticum urartu34.882e-73 253
LLPS-Nia-1208Nicotiana attenuata34.887e-83 278
LLPS-Hea-2497Helianthus annuus34.814e-81 274
LLPS-Zem-0181Zea mays34.82e-75 258
LLPS-Sob-1066Sorghum bicolor34.82e-76 261
LLPS-Tag-1137Taeniopygia guttata34.771e-80 274
LLPS-Php-0679Physcomitrella patens34.711e-77 265
LLPS-Gaa-1249Gasterosteus aculeatus34.698e-79 269
LLPS-Orl-0287Oryzias latipes34.697e-81 275
LLPS-Asm-0358Astyanax mexicanus34.692e-78 270
LLPS-Icp-0033Ictalurus punctatus34.691e-78 268
LLPS-Thc-1173Theobroma cacao34.665e-81 273
LLPS-Dac-0659Daucus carota34.662e-80 271
LLPS-Gor-1822Gossypium raimondii34.667e-81 273
LLPS-Pot-1132Populus trichocarpa34.583e-78 266
LLPS-Arl-0130Arabidopsis lyrata34.462e-80 272
LLPS-Scc-0616Schizosaccharomyces cryophilus34.464e-77 259
LLPS-Mua-1412Musa acuminata34.343e-74 255
LLPS-Orc-0263Oryctolagus cuniculus34.251e-26 117
LLPS-Viv-0511Vitis vinifera34.191e-76 262
LLPS-Cus-1138Cucumis sativus34.174e-78 266
LLPS-Phv-0104Phaseolus vulgaris33.883e-78 266
LLPS-Glm-0289Glycine max33.82e-78 266
LLPS-Amt-0851Amborella trichopoda33.85e-76 260
LLPS-Miv-0743Microbotryum violaceum33.735e-40 157
LLPS-Via-1083Vigna angularis33.643e-77 263
LLPS-Prp-0060Prunus persica33.491e-75 259
LLPS-Sot-0175Solanum tuberosum33.332e-78 266
LLPS-Scj-0825Schizosaccharomyces japonicus33.183e-77 260
LLPS-Sol-1219Solanum lycopersicum33.11e-77 265
LLPS-Nef-0589Neosartorya fischeri32.72e-70 243
LLPS-Asc-0739Aspergillus clavatus32.632e-68 239
LLPS-Asfu-0242Aspergillus fumigatus32.561e-70 244
LLPS-Spr-0736Sporisorium reilianum32.54e-74 253
LLPS-Ast-0753Aspergillus terreus32.421e-66 234
LLPS-Asg-0774Ashbya gossypii32.247e-73 249
LLPS-Zyt-0069Zymoseptoria tritici32.26e-70 242
LLPS-Asn-0014Aspergillus nidulans32.073e-67 234
LLPS-Usm-0490Ustilago maydis31.891e-72 249
LLPS-Aso-0648Aspergillus oryzae31.863e-68 238
LLPS-Trr-0402Trichoderma reesei31.853e-74 254
LLPS-Asf-0290Aspergillus flavus31.664e-67 236
LLPS-Mao-1112Magnaporthe oryzae31.656e-76 258
LLPS-Trv-1046Trichoderma virens31.655e-74 253
LLPS-Dos-0920Dothistroma septosporum31.562e-72 249
LLPS-Asni-0130Aspergillus niger31.453e-65 229
LLPS-Map-0701Magnaporthe poae31.453e-73 250
LLPS-Pug-0121Puccinia graminis31.433e-64 227
LLPS-Cii-0136Ciona intestinalis31.351e-79 269
LLPS-Blg-0096Blumeria graminis31.291e-46 174
LLPS-Coo-0743Colletotrichum orbiculare31.285e-72 248
LLPS-Gag-0650Gaeumannomyces graminis31.242e-75 257
LLPS-Abg-0852Absidia glauca31.217e-74 251
LLPS-Cis-0111Ciona savignyi31.212e-71 249
LLPS-Tum-0749Tuber melanosporum31.143e-66 232
LLPS-Put-0439Puccinia triticina30.953e-50 187
LLPS-Fus-0201Fusarium solani30.952e-68 238
LLPS-Fuo-0475Fusarium oxysporum30.931e-71 246
LLPS-Nec-0340Neurospora crassa30.926e-69 239
LLPS-Fuv-0001Fusarium verticillioides30.722e-71 246
LLPS-Ora-1754Ornithorhynchus anatinus30.572e-1374.7
LLPS-Cogr-0447Colletotrichum graminicola30.513e-71 246
LLPS-Beb-0572Beauveria bassiana30.471e-70 244
LLPS-Sac-0396Saccharomyces cerevisiae30.152e-69 240
LLPS-Crn-0210Cryptococcus neoformans29.912e-57 208
LLPS-Cae-1331Caenorhabditis elegans29.912e-66 235
LLPS-Kop-0086Komagataella pastoris29.281e-57 207
LLPS-Yal-0030Yarrowia lipolytica29.26e-64 225
LLPS-Phn-0253Phaeosphaeria nodorum29.044e-63 223
LLPS-Mel-0324Melampsora laricipopulina28.71e-58 210
LLPS-Pyt-0260Pyrenophora teres28.63e-58 210
LLPS-Cog-0209Colletotrichum gloeosporioides28.513e-57 207
LLPS-Pytr-0028Pyrenophora triticirepentis28.128e-59 212
LLPS-Lem-0531Leptosphaeria maculans27.992e-59 216