• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Cas-1577
PPP2R1B

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X3
Gene Name: PPP2R1B
Ensembl Gene: ENSTSYG00000007244.2
Ensembl Protein: ENSTSYP00000006667.2
Organism: Carlito syrichta
Taxa ID: 1868482
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Stress granulePredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MAGAAAPGTG  LGAAGGDGDD  SLYPIAVLID  ELRNEDVQLR  LNSIKKLSTI  ALALGVERTR  60
61    TELLPFLTDT  IYDEDEVLLA  LAEQLGNFTG  LVGGPDFAHC  LLPPLESLAT  VEETVVRDRA  120
121   VESLRQISQE  HTPVALEVHF  VPLVKRLASG  DWFTSRTSAC  GLFSVCYPRA  SNAVKEEIRQ  180
181   HFRSLCSDDT  PMVRRAAASK  LGEFAKVLEL  DSVKSEIVPL  FTNLASDEQD  SVRLLAVEAC  240
241   VSIAQLLSQD  DLEALVMPTL  RQAAEDKSWR  VRYMVADKFS  ELQKAVGPKI  TLNDLIPAFQ  300
301   NLLKDCEAEV  RAAAAHKVKE  LCENLPIEGR  ETIIMNQILP  YIKELVSDMN  QHVKSALASV  360
361   IMGLSTILGK  ENTIEHLLPL  FLAQLKDECP  EVRLNIISNL  DCVNEVIGIR  QLSQSLLPAI  420
421   VELAKDAKWR  VRLAIIEYMP  LLAGQLGVEF  FDEKLNSLCM  AWLVDHVYAI  REAATNNLMK  480
481   LVQKFGTEWA  QNTIVPKVLV  MADDPNYLHR  MTTLFCINAL  SEACGQEITT  KQMLPIVLKM  540
541   AGDQVANVRF  NVAKSLQKIG  PILDTNALQG  EVRPVLQKLG  QDEDMDVKYF  AQEAISVMAQ  600
601   RLRKLDLPVK  DSEELSAPRA  DKNHFLSPTV  PGDNTRKGPA  YQLHVNTRDK  LAQLELAERV  660
661   HFPQSRD  667
Nucleotide CDS Sequence (FASTA)
1     ATGGCGGGTG  CGGCGGCACC  CGGGACCGGC  CTGGGGGCTG  CGGGCGGAGA  TGGAGACGAT  60
61    TCGCTCTACC  CGATCGCGGT  TTTAATCGAC  GAGCTCCGCA  ACGAGGACGT  GCAGCCTCCT  120
121   TTGGAAAGCC  TGGCAACTGT  GGAAGAGACT  GTTGTTCGTG  ATAGGGCTGT  GGAGTCCCTG  180
181   AGACAGATCT  CCCAGGAGCA  TACTCCTGTT  GCTCTGGAAG  TTCATTTTGT  ACCTCTGGTG  240
241   AAACGCCTAG  CCAGTGGCGA  TTGGTTCACC  TCTCGAACAT  CTGCATGTGG  TTTGTTCAGC  300
301   GTTTGCTATC  CCAGGGCTTC  AAATGCTGTC  AAGGAAGAAA  TTAGACAGCA  CTTCCGTTCT  360
361   TTGTGCTCAG  ATGACACACC  AATGGTACGA  CGTGCTGCTG  CTTCCAAGTT  GGGTGAATTT  420
421   GCAAAAGTTT  TGGAATTAGA  CAGTGTGAAA  AGTGAAATTG  TTCCATTGTT  CACGAATCTA  480
481   GCTTCAGATG  AACAGGATTC  AGTACGACTT  CTAGCTGTGG  AAGCTTGTGT  CAGTATTGCT  540
541   CAGTTACTGT  CCCAAGATGA  TCTTGAGGCC  TTGGTGATGC  CTACACTTCG  ACAAGCAGCA  600
601   GAAGATAAAT  CCTGGCGAGT  TCGCTATATG  GTAGCTGACA  AATTTTCAGA  GCTCCAGAAA  660
661   GCTGTGGGTC  CTAAAATCAC  CCTAAATGAC  CTCATCCCCG  CCTTTCAGAA  CCTACTGAAA  720
721   GACTGTGAAG  CTGAAGTCCG  AGCAGCTGCT  GCCCACAAAG  TAAAAGAACT  TTGTGAGAAC  780
781   TTGCCTATTG  AAGGTAGAGA  GACCATAATT  ATGAATCAAA  TCTTGCCTTA  TATAAAGGAA  840
841   TTAGTATCCG  ATATGAACCA  ACATGTCAAA  TCGGCTCTAG  CTTCTGTAAT  TATGGGATTG  900
901   TCTACGATTT  TGGGTAAAGA  GAATACCATT  GAACATCTTC  TGCCTCTTTT  TTTAGCTCAG  960
961   TTAAAGGATG  AGTGTCCTGA  AGTTCGTTTG  AATATCATCT  CCAATTTGGA  TTGTGTAAAT  1020
1021  GAAGTGATTG  GAATCCGACA  GCTCTCTCAG  TCTCTCCTTC  CTGCCATAGT  GGAGCTGGCC  1080
1081  AAAGATGCCA  AGTGGAGGGT  CCGGCTGGCC  ATCATTGAGT  ATATGCCGCT  GCTAGCAGGC  1140
1141  CAGCTGGGTG  TGGAATTCTT  TGATGAAAAG  CTGAATTCTT  TATGTATGGC  CTGGCTCGTG  1200
1201  GACCATGTAT  ATGCCATCCG  AGAAGCTGCT  ACCAACAACC  TCATGAAACT  AGTTCAGAAG  1260
1261  TTTGGTACAG  AGTGGGCCCA  AAATACCATC  GTTCCCAAAG  TGTTGGTAAT  GGCAGATGAT  1320
1321  CCTAATTACT  TACATAGGAT  GACCACTTTA  TTCTGCATTA  ATGCACTGTC  TGAAGCCTGT  1380
1381  GGTCAGGAAA  TAACCACTAA  GCAAATGCTG  CCCATCGTAT  TAAAGATGGC  AGGAGACCAA  1440
1441  GTAGCAAATG  TTCGTTTCAA  TGTGGCCAAA  TCTCTACAAA  AAATTGGACC  AATTTTAGAT  1500
1501  ACCAATGCTT  TGCAGGGGGA  AGTTAGGCCA  GTACTACAGA  AGTTAGGTCA  AGATGAAGAC  1560
1561  ATGGATGTCA  AATACTTTGC  ACAAGAAGCT  ATCAGTGTGA  TGGCACAAAG  GCTGAGGAAG  1620
1621  CTAGATCTTC  CTGTGAAGGA  CAGTGAAGAG  CTCAGCGCCC  CTAGGGCTGA  CAAGAACCAC  1680
1681  TTCCTGAGCC  CCACCGTGCC  TGGAGACAAC  ACCAGGAAGG  GACCAGCGTA  TCAACTGCAT  1740
1741  GTAAATACCA  GAGACAAACT  TGCCCAACTG  GAACTTGCAG  AACGAGTGCA  TTTTCCCCAA  1800
1801  AGCAGAGACT  GA  1812

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Otg-3256Otolemur garnettii97.750.01161
LLPS-Caf-2272Canis familiaris97.410.01150
LLPS-Chs-3072Chlorocebus sabaeus96.890.01146
LLPS-Ran-1977Rattus norvegicus96.890.01154
LLPS-Ict-4215Ictidomys tridecemlineatus96.60.01216
LLPS-Sus-1370Sus scrofa96.090.01197
LLPS-Fec-2497Felis catus96.030.01134
LLPS-Orc-1411Oryctolagus cuniculus95.790.01210
LLPS-Bot-1422Bos taurus95.790.01203
LLPS-Caj-2790Callithrix jacchus95.340.01133
LLPS-Eqc-0437Equus caballus95.320.01193
LLPS-Sah-1244Sarcophilus harrisii94.980.01054
LLPS-Rhb-3400Rhinopithecus bieti94.740.01250
LLPS-Man-2652Macaca nemestrina94.740.01250
LLPS-Mam-1230Macaca mulatta94.740.01250
LLPS-Cea-4166Cercocebus atys94.740.01250
LLPS-Maf-0200Macaca fascicularis94.740.01249
LLPS-Paa-1753Papio anubis94.590.01249
LLPS-Mal-4022Mandrillus leucophaeus94.590.01214
LLPS-Cap-0058Cavia porcellus94.330.01186
LLPS-Pat-2397Pan troglodytes94.280.01246
LLPS-Aon-0850Aotus nancymaae94.260.01207
LLPS-Tut-2051Tursiops truncatus93.970.01239
LLPS-Hos-2517Homo sapiens93.820.01240
LLPS-Nol-4084Nomascus leucogenys93.510.01229
LLPS-Dio-1680Dipodomys ordii93.440.01095
LLPS-Fud-0303Fukomys damarensis93.350.01171
LLPS-Myl-2358Myotis lucifugus93.310.01014
LLPS-Urm-1539Ursus maritimus93.190.01169
LLPS-Mod-1314Monodelphis domestica93.160.01112
LLPS-Mea-1314Mesocricetus auratus91.540.01243
LLPS-Aim-0798Ailuropoda melanoleuca91.410.01243
LLPS-Mup-1116Mustela putorius furo91.250.01237
LLPS-Loa-0596Loxodonta africana91.110.01244
LLPS-Ova-0688Ovis aries90.950.01227
LLPS-Mum-3896Mus musculus90.490.01237
LLPS-Leo-0619Lepisosteus oculatus90.170.01071
LLPS-Scf-2916Scleropages formosus90.160.01072
LLPS-Lac-1158Latimeria chalumnae89.980.01076
LLPS-Gaa-1538Gasterosteus aculeatus89.980.01071
LLPS-Orn-1642Oreochromis niloticus89.810.01069
LLPS-Icp-1404Ictalurus punctatus89.810.01069
LLPS-Scm-0132Scophthalmus maximus89.760.01065
LLPS-Pof-0248Poecilia formosa89.460.01069
LLPS-Orl-2630Oryzias latipes89.460.01063
LLPS-Xim-0092Xiphophorus maculatus89.460.01069
LLPS-Tar-1575Takifugu rubripes89.460.01060
LLPS-Asm-3314Astyanax mexicanus89.290.01063
LLPS-Dar-1373Danio rerio89.120.01060
LLPS-Ora-0695Ornithorhynchus anatinus89.120.01065
LLPS-Ten-2959Tetraodon nigroviridis88.830.0 636
LLPS-Poa-0229Pongo abelii86.860.01135
LLPS-Pes-1479Pelodiscus sinensis86.717e-80 258
LLPS-Pap-3073Pan paniscus86.530.01040
LLPS-Gog-2543Gorilla gorilla86.530.01040
LLPS-Anc-1252Anolis carolinensis86.360.01037
LLPS-Xet-2242Xenopus tropicalis83.820.0 986
LLPS-Fia-3005Ficedula albicollis81.679e-24 100
LLPS-Anp-1484Anas platyrhynchos80.773e-37 138
LLPS-Tag-1552Taeniopygia guttata75.193e-126 382
LLPS-Drm-1136Drosophila melanogaster72.630.0 820
LLPS-Cii-1356Ciona intestinalis70.120.0 861
LLPS-Cis-0698Ciona savignyi68.210.0 825
LLPS-Cae-0133Caenorhabditis elegans62.370.0 724
LLPS-Hea-0403Helianthus annuus58.030.0 671
LLPS-Dac-1936Daucus carota58.010.0 667
LLPS-Mua-0501Musa acuminata57.690.0 665
LLPS-Mae-0043Manihot esculenta57.670.0 662
LLPS-Sob-2236Sorghum bicolor57.510.0 657
LLPS-Nia-0504Nicotiana attenuata57.490.0 660
LLPS-Brr-2699Brassica rapa57.490.0 658
LLPS-Sol-1237Solanum lycopersicum57.490.0 660
LLPS-Sot-1250Solanum tuberosum57.490.0 660
LLPS-Pot-1417Populus trichocarpa57.370.0 664
LLPS-Vir-0801Vigna radiata57.350.0 646
LLPS-Hov-0509Hordeum vulgare57.340.0 664
LLPS-Coc-1057Corchorus capsularis57.320.0 656
LLPS-Met-0728Medicago truncatula57.320.0 659
LLPS-Cus-0413Cucumis sativus57.320.0 657
LLPS-Prp-0992Prunus persica57.190.0 661
LLPS-Amt-0448Amborella trichopoda57.170.0 657
LLPS-Tra-0270Triticum aestivum57.170.0 660
LLPS-Bro-0175Brassica oleracea57.145e-161 477
LLPS-Thc-0592Theobroma cacao57.140.0 657
LLPS-Ors-1128Oryza sativa56.990.0 659
LLPS-Org-0321Oryza glaberrima56.990.0 659
LLPS-Orni-0892Oryza nivara56.990.0 659
LLPS-Orb-1281Oryza barthii56.990.0 659
LLPS-Ori-0326Oryza indica56.990.0 659
LLPS-Brd-2193Brachypodium distachyon56.990.0 654
LLPS-Lep-0103Leersia perrieri56.990.0 659
LLPS-Orgl-0579Oryza glumaepatula56.990.0 659
LLPS-Phv-0485Phaseolus vulgaris56.970.0 658
LLPS-Art-0279Arabidopsis thaliana56.970.0 658
LLPS-Zem-0039Zea mays56.970.0 662
LLPS-Arl-0317Arabidopsis lyrata56.970.0 664
LLPS-Via-0910Vigna angularis56.970.0 657
LLPS-Viv-0848Vitis vinifera56.820.0 659
LLPS-Gor-1183Gossypium raimondii56.80.0 657
LLPS-Sei-1838Setaria italica56.80.0 660
LLPS-Glm-2239Glycine max56.790.0 657
LLPS-Brn-0233Brassica napus56.70.0 661
LLPS-Orbr-1642Oryza brachyantha56.510.0 587
LLPS-Php-0294Physcomitrella patens55.860.0 650
LLPS-Orr-0287Oryza rufipogon55.650.0 650
LLPS-Sem-0412Selaginella moellendorffii55.590.0 642
LLPS-Orp-0931Oryza punctata54.550.0 641
LLPS-Spr-0095Sporisorium reilianum54.10.0 622
LLPS-Usm-0664Ustilago maydis53.970.0 616
LLPS-Trr-0710Trichoderma reesei53.340.0 618
LLPS-Chr-0546Chlamydomonas reinhardtii53.040.0 591
LLPS-Phn-0294Phaeosphaeria nodorum52.990.0 617
LLPS-Fus-0356Fusarium solani52.940.0 619
LLPS-Pytr-0336Pyrenophora triticirepentis52.920.0 621
LLPS-Pyt-0618Pyrenophora teres52.920.0 621
LLPS-Lem-0418Leptosphaeria maculans52.750.0 619
LLPS-Tum-1243Tuber melanosporum52.670.0 605
LLPS-Trv-0860Trichoderma virens52.650.0 619
LLPS-Cogr-0043Colletotrichum graminicola52.520.0 621
LLPS-Map-1095Magnaporthe poae52.440.0 618
LLPS-Gag-0983Gaeumannomyces graminis52.440.0 619
LLPS-Fuv-0929Fusarium verticillioides52.420.0 618
LLPS-Scp-0718Schizosaccharomyces pombe52.40.0 602
LLPS-Crn-1011Cryptococcus neoformans52.320.0 581
LLPS-Coo-0407Colletotrichum orbiculare52.260.0 613
LLPS-Nef-0922Neosartorya fischeri52.250.0 614
LLPS-Cog-0880Colletotrichum gloeosporioides52.180.0 619
LLPS-Dos-0163Dothistroma septosporum52.160.0 607
LLPS-Mao-0468Magnaporthe oryzae52.10.0 617
LLPS-Asn-1065Aspergillus nidulans52.090.0 609
LLPS-Asc-1044Aspergillus clavatus52.090.0 615
LLPS-Ved-1116Verticillium dahliae52.00.0 619
LLPS-Asfu-0230Aspergillus fumigatus51.920.0 612
LLPS-Scj-1048Schizosaccharomyces japonicus51.90.0 585
LLPS-Scc-1347Schizosaccharomyces cryophilus51.810.0 587
LLPS-Miv-0108Microbotryum violaceum51.790.0 549
LLPS-Beb-0584Beauveria bassiana51.760.0 601
LLPS-Ast-0446Aspergillus terreus51.750.0 616
LLPS-Asni-0118Aspergillus niger51.590.0 607
LLPS-Zyt-0347Zymoseptoria tritici51.330.0 607
LLPS-Nec-0150Neurospora crassa51.090.0 606
LLPS-Put-0461Puccinia triticina51.030.0 570
LLPS-Mel-0197Melampsora laricipopulina50.940.0 564
LLPS-Scs-0286Sclerotinia sclerotiorum50.920.0 611
LLPS-Pug-0628Puccinia graminis50.690.0 563
LLPS-Fuo-0783Fusarium oxysporum50.590.0 577
LLPS-Blg-0276Blumeria graminis50.250.0 593
LLPS-Asf-0159Aspergillus flavus50.170.0 588
LLPS-Aso-0864Aspergillus oryzae50.170.0 588
LLPS-Abg-0350Absidia glauca49.830.0 571
LLPS-Gas-0284Galdieria sulphuraria48.714e-174 517
LLPS-Chc-0570Chondrus crispus47.241e-162 491
LLPS-Osl-0064Ostreococcus lucimarinus47.110.0 536
LLPS-Cym-0661Cyanidioschyzon merolae47.031e-157 475
LLPS-Asg-0382Ashbya gossypii44.261e-151 459
LLPS-Kop-0684Komagataella pastoris44.269e-152 461
LLPS-Sac-0484Saccharomyces cerevisiae44.138e-159 479
LLPS-Yal-0557Yarrowia lipolytica43.492e-155 470
LLPS-Orm-0557Oryza meridionalis38.497e-46 171
LLPS-Meg-2309Meleagris gallopavo25.757e-0757.0
LLPS-Gaga-2730Gallus gallus25.758e-0756.6