LLPS-Caj-0737
CASC3
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | CASC3, exon junction complex subunit |
| Gene Name: | CASC3 |
| Ensembl Gene: | ENSCJAG00000016032.3 |
| Ensembl Protein: | ENSCJAP00000029512.3 |
| Organism: | Callithrix jacchus |
| Taxa ID: | 9483 |
| LLPS Type: | LLPS regulator |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Nuclear speckle, Nucleolus, P-body, Stress granule, Chromatoid body | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSCJAT00000031187.3 | ENSCJAP00000029512.3 |
| Ensembl | ENSCJAT00000078883.1 | ENSCJAP00000065747.1 |
| UniProt | U3F3U6, U3F3U6_CALJA, F7IH43 | |
| GeneBank | GAMP01000573, GAMR01000468 | JAB33464.1, JAB52182.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MADRRRQRAS QDTEDEESGA SGSDSGGSPL RGGGSCSGSA GGGGSGSLSS QRGGRIGALH 60 61 LRRVESGGAK SAEESECESE DGIEGDAVLS DYESAEDSEG EEGEYSEEEN SKVELKSEAN 120 121 DAVNSSTKEE KGEEKPDTKG TVTGERQSGD GQESTEPVEN KAGKKGPKQL DDDEDRKNPA 180 181 YIPRKGLFFE HDLRGQTQEE EVRPKGRQRK LWKDEGRWEH DKFREDEQAP KSRQELIALY 240 241 GYDIRSAHNP DDIKPRRIRK PRYGSPPQRD PNWNVEKLNK SHRHQGLGGT LPPRTFINRN 300 301 AAGTGRMSAP RNYSRSGAFK ESRPGFRPVE AGGQQGGWSG ETVKHDTSYR SRHLEQTCVR 360 361 DPSPEANAPV PGSPEKEETA SETLAAAPDT TPPAPDRPIE KKSYSRARRT RTKVGDAVKL 420 421 AEEVPPPPEG LIPAPPVPET TATPPTKTGN WEAPVDSTTS GLEQDVAQLN IAEQNWSPGQ 480 481 PSFLQPRELR GMANHIHMGA GPPPQFNRME EMGVQGGRAK RYSSQRQRPV PEPPAPPVHI 540 541 SIVEGHYYDP PQFQGPIYTH GDSPAPLPPQ GMLVQPEMHL PHPGLHPHQT PAPLPNPGLY 600 601 PPPVSMSPGQ PPPQQLLAPT YFSAPGVIFG NPSYPYAPGA LPPPPPPHLY PNTQAPSQVY 660 661 GGVTYYNPAQ QQVQPKPSPP RRTPQPVTIK PPPPEVVSRG SS 702 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGCGGACC GGCGGCGGCA GCGAGCTTCT CAAGATACCG AGGACGAGGA ATCTGGTGCT 60 61 TCGGGCTCAG ACAGCGGCGG CTCCCCGTTA AGGGGCGGCG GTAGCTGCAG CGGTAGCGCC 120 121 GGAGGCGGCG GCAGCGGCTC TCTGTCTTCA CAGCGCGGAG GCCGAATCGG GGCCCTTCAT 180 181 CTGCGGCGGG TGGAAAGCGG GGGCGCCAAG AGCGCTGAGG AGTCGGAGTG TGAGAGTGAA 240 241 GATGGCATTG AAGGTGATGC TGTTCTCTCG GATTATGAAA GTGCAGAAGA CTCGGAAGGT 300 301 GAAGAAGGTG AATACAGTGA AGAGGAAAAC TCCAAAGTGG AGCTGAAATC AGAAGCTAAT 360 361 GATGCTGTTA ATTCTTCAAC AAAAGAAGAG AAGGGAGAAG AAAAGCCTGA CACCAAAGGC 420 421 ACTGTGACGG GAGAGAGGCA AAGTGGGGAC GGACAGGAGA GCACGGAGCC TGTGGAGAAC 480 481 AAAGCAGGTA AAAAGGGCCC TAAGCAGTTG GATGATGATG AAGATCGGAA GAATCCAGCA 540 541 TACATACCTC GGAAAGGGCT ATTCTTTGAG CATGATCTTC GAGGGCAAAC TCAGGAGGAA 600 601 GAAGTCAGAC CCAAGGGGCG TCAGCGAAAG CTATGGAAGG ATGAGGGTCG CTGGGAGCAT 660 661 GACAAGTTCC GGGAAGATGA GCAGGCCCCA AAGTCTCGAC AGGAGCTCAT TGCTCTGTAT 720 721 GGTTATGACA TTCGCTCAGC TCACAATCCT GATGACATCA AACCCCGAAG AATCCGGAAA 780 781 CCCCGATATG GGAGTCCTCC ACAAAGAGAT CCAAACTGGA ATGTTGAGAA GCTAAACAAG 840 841 TCCCATCGCC ACCAGGGTCT TGGGGGTACC CTACCACCAA GGACATTTAT TAACAGGAAT 900 901 GCTGCAGGTA CCGGCCGCAT GTCTGCACCG AGGAATTATT CTCGATCTGG GGCCTTCAAG 960 961 GAAAGTCGTC CTGGTTTTAG GCCTGTGGAA GCTGGTGGGC AGCAGGGTGG CTGGTCTGGT 1020 1021 GAGACTGTTA AGCATGATAC TAGTTACCGG TCACGGCATC TAGAGCAGAC TTGTGTGAGG 1080 1081 GATCCATCTC CAGAAGCAAA TGCTCCAGTG CCTGGCAGTC CTGAGAAGGA AGAGACAGCC 1140 1141 TCAGAGACAT TAGCTGCTGC TCCTGATACC ACACCACCAG CCCCGGACAG GCCCATTGAG 1200 1201 AAGAAATCCT ATTCCCGGGC AAGAAGAACC CGAACCAAGG TTGGAGATGC AGTCAAGCTT 1260 1261 GCAGAAGAGG TGCCCCCTCC TCCTGAGGGG CTGATTCCAG CACCTCCAGT CCCAGAAACC 1320 1321 ACCGCAACTC CACCTACTAA GACTGGGAAC TGGGAGGCTC CAGTGGATTC CACTACAAGT 1380 1381 GGACTTGAAC AAGATGTGGC ACAACTAAAT ATAGCAGAAC AGAATTGGAG TCCCGGGCAG 1440 1441 CCTTCTTTCC TGCAGCCACG GGAACTTCGA GGTATGGCCA ACCATATACA CATGGGAGCA 1500 1501 GGACCTCCAC CTCAGTTTAA CCGGATGGAA GAAATGGGTG TCCAGGGTGG TCGAGCCAAA 1560 1561 CGCTATTCAT CCCAGCGGCA AAGACCTGTG CCAGAGCCCC CTGCCCCTCC AGTGCATATC 1620 1621 AGTATCGTGG AGGGACATTA CTATGATCCA CCACAGTTCC AGGGACCAAT CTATACCCAT 1680 1681 GGTGACAGCC CTGCCCCGCT GCCTCCACAG GGCATGCTTG TGCAGCCAGA AATGCACCTT 1740 1741 CCCCACCCAG GTTTACATCC CCACCAGACA CCAGCGCCTC TGCCCAATCC GGGTCTCTAT 1800 1801 CCCCCACCAG TGTCCATGTC TCCTGGACAG CCACCACCTC AGCAGTTGCT TGCTCCTACT 1860 1861 TACTTTTCTG CTCCAGGCGT TATCTTTGGT AATCCCAGTT ACCCTTATGC TCCAGGGGCA 1920 1921 CTGCCTCCCC CACCGCCGCC TCATCTATAT CCTAATACGC AGGCCCCATC GCAGGTATAT 1980 1981 GGAGGAGTGA CCTACTATAA CCCCGCCCAG CAGCAGGTGC AACCAAAGCC CTCCCCACCC 2040 2041 CGGAGGACTC CCCAGCCAGT CACCATCAAG CCCCCTCCAC CTGAGGTTGT AAGCAGGGGT 2100 2101 TCCAGTTAA 2109 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Rhb-0936 | Rhinopithecus bieti | 95.7 | 0.0 | 863 |
| LLPS-Chs-2423 | Chlorocebus sabaeus | 95.4 | 0.0 | 862 |
| LLPS-Paa-3326 | Papio anubis | 95.21 | 0.0 | 806 |
| LLPS-Mal-2625 | Mandrillus leucophaeus | 95.08 | 0.0 | 849 |
| LLPS-Hos-0037 | Homo sapiens | 94.95 | 0.0 | 848 |
| LLPS-Pap-0002 | Pan paniscus | 94.8 | 0.0 | 847 |
| LLPS-Gog-4356 | Gorilla gorilla | 94.65 | 0.0 | 859 |
| LLPS-Maf-2052 | Macaca fascicularis | 94.23 | 0.0 | 855 |
| LLPS-Cea-1085 | Cercocebus atys | 94.23 | 0.0 | 855 |
| LLPS-Poa-2192 | Pongo abelii | 93.61 | 0.0 | 853 |
| LLPS-Nol-4198 | Nomascus leucogenys | 93.61 | 0.0 | 855 |
| LLPS-Caf-0549 | Canis familiaris | 93.16 | 0.0 | 842 |
| LLPS-Aim-3655 | Ailuropoda melanoleuca | 93.02 | 0.0 | 839 |
| LLPS-Fec-4388 | Felis catus | 92.87 | 0.0 | 838 |
| LLPS-Mam-3769 | Macaca mulatta | 92.75 | 0.0 | 854 |
| LLPS-Otg-1181 | Otolemur garnettii | 92.6 | 0.0 | 839 |
| LLPS-Mup-0310 | Mustela putorius furo | 92.27 | 0.0 | 834 |
| LLPS-Eqc-2666 | Equus caballus | 92.12 | 0.0 | 835 |
| LLPS-Orc-1516 | Oryctolagus cuniculus | 91.68 | 0.0 | 824 |
| LLPS-Urm-2105 | Ursus maritimus | 91.67 | 0.0 | 825 |
| LLPS-Ict-4080 | Ictidomys tridecemlineatus | 91.38 | 0.0 | 829 |
| LLPS-Ova-1428 | Ovis aries | 91.23 | 0.0 | 836 |
| LLPS-Ran-2396 | Rattus norvegicus | 91.1 | 5e-111 | 356 |
| LLPS-Bot-0316 | Bos taurus | 90.6 | 0.0 | 822 |
| LLPS-Loa-1381 | Loxodonta africana | 90.04 | 0.0 | 816 |
| LLPS-Sus-2002 | Sus scrofa | 89.72 | 0.0 | 801 |
| LLPS-Myl-2475 | Myotis lucifugus | 88.15 | 0.0 | 796 |
| LLPS-Mea-2001 | Mesocricetus auratus | 88.09 | 0.0 | 627 |
| LLPS-Aon-1734 | Aotus nancymaae | 87.94 | 0.0 | 750 |
| LLPS-Man-3084 | Macaca nemestrina | 87.85 | 9e-87 | 279 |
| LLPS-Cap-0241 | Cavia porcellus | 87.18 | 0.0 | 764 |
| LLPS-Mum-1640 | Mus musculus | 85.99 | 0.0 | 794 |
| LLPS-Ere-0298 | Erinaceus europaeus | 85.94 | 0.0 | 639 |
| LLPS-Fud-1017 | Fukomys damarensis | 84.25 | 0.0 | 739 |
| LLPS-Sah-2050 | Sarcophilus harrisii | 80.93 | 0.0 | 707 |
| LLPS-Mod-2025 | Monodelphis domestica | 76.16 | 0.0 | 659 |
| LLPS-Ten-0967 | Tetraodon nigroviridis | 74.36 | 9e-48 | 183 |
| LLPS-Scf-0524 | Scleropages formosus | 72.97 | 7e-60 | 220 |
| LLPS-Gaga-0599 | Gallus gallus | 72.97 | 0.0 | 661 |
| LLPS-Icp-0818 | Ictalurus punctatus | 72.39 | 2e-52 | 198 |
| LLPS-Gaa-1463 | Gasterosteus aculeatus | 70.59 | 2e-46 | 169 |
| LLPS-Tag-0086 | Taeniopygia guttata | 70.36 | 0.0 | 546 |
| LLPS-Meg-1398 | Meleagris gallopavo | 69.91 | 0.0 | 654 |
| LLPS-Orn-2003 | Oreochromis niloticus | 69.54 | 6e-52 | 196 |
| LLPS-Fia-2899 | Ficedula albicollis | 68.98 | 0.0 | 638 |
| LLPS-Pat-2643 | Pan troglodytes | 68.64 | 7e-120 | 378 |
| LLPS-Leo-1092 | Lepisosteus oculatus | 67.93 | 4e-38 | 155 |
| LLPS-Pes-0233 | Pelodiscus sinensis | 67.62 | 6e-131 | 402 |
| LLPS-Tar-1501 | Takifugu rubripes | 67.61 | 6e-49 | 187 |
| LLPS-Anc-0731 | Anolis carolinensis | 67.48 | 0.0 | 606 |
| LLPS-Scm-1187 | Scophthalmus maximus | 67.36 | 7e-48 | 184 |
| LLPS-Pof-1369 | Poecilia formosa | 65.64 | 5e-52 | 196 |
| LLPS-Xim-2835 | Xiphophorus maculatus | 62.78 | 1e-51 | 196 |
| LLPS-Ora-2055 | Ornithorhynchus anatinus | 62.13 | 2e-80 | 273 |
| LLPS-Orl-0113 | Oryzias latipes | 56.47 | 1e-43 | 171 |
| LLPS-Xet-3491 | Xenopus tropicalis | 55.26 | 1e-145 | 448 |
| LLPS-Asm-2609 | Astyanax mexicanus | 53.27 | 6e-46 | 178 |
| LLPS-Lac-0850 | Latimeria chalumnae | 52.84 | 7e-150 | 460 |
| LLPS-Dar-1885 | Danio rerio | 52.53 | 2e-41 | 165 |
| LLPS-Cae-1203 | Caenorhabditis elegans | 39.02 | 1e-09 | 65.5 |
| LLPS-Cii-0159 | Ciona intestinalis | 33.15 | 5e-11 | 69.3 |