• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Caf-1714
TRAF6

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: TNF receptor associated factor 6
Gene Name: TRAF6
Ensembl Gene: ENSCAFG00000006813.3
Ensembl Protein: ENSCAFP00000010159.3
Organism: Canis familiaris
Taxa ID: 9615
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
P-bodyPredicted from orthologs(View)

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblENSCAFT00000010962.3ENSCAFP00000010159.3
UniProtE2RDE8, E2RDE8_CANLF
GeneBankAAEX03011373

▼ SEQUENCE

Protein Sequence (FASTA)
1     MSLLNCENSC  GSSQSESDCC  PAMASSCSAA  VKDDSVSGTT  STGNLSSSFM  EEIQGYDVEF  60
61    DPPLESKYEC  PICLMALREA  VQTPCGHRFC  KACIIKSIRD  AGHKCPVDNE  ILLENQLFPD  120
121   NFAKREILSL  MVKCPNEGCL  HKMELRHLED  HQLHCEFALM  NCLQCQRTFQ  KCQLNIHILK  180
181   ECPRRQVSCM  NCAALMAFED  KEIHDQNCPL  ANVICEYCNT  MLIREQMPNH  YDLDCPTAPI  240
241   PCTFSTFGCH  VKMQRNHLAR  HLQENTQSHM  RMLGQAVQSL  SLALAPVPQR  DVPPYDSSSV  300
301   SRVSSTCHPE  VQNFQETIQQ  LEGRLVRQDH  QIRELTAKME  TQSMHVSELK  RNIRTLEDKV  360
361   AEIEAQQCNG  IYIWKIGNFG  MHLKSQEEEK  PVVIHSPGFY  TGKPGYKLCM  RLHLQLPTAQ  420
421   RCANYISLFV  HTMQGEYDSH  LPWPFQGTIR  LAILDQSEAP  VRQNHEEIMD  AKPELLAFQR  480
481   PTIPRNPKGS  CSALMGLRYT  AKIKVTQRSC  SAQLPLQPPA  HHWFPVHFLA  SRCPLAAAVP  540
541   STQLLRILAA  PPSRLGALHC  CC  562
Nucleotide CDS Sequence (FASTA)
1     ATGAGTCTGC  TAAACTGTGA  AAACAGCTGT  GGATCCAGCC  AGTCTGAAAG  CGACTGCTGT  60
61    CCTGCCATGG  CCAGCTCCTG  TAGCGCCGCA  GTGAAAGATG  ACAGTGTGAG  TGGAACCACC  120
121   AGCACGGGGA  ACCTCTCCAG  CTCTTTTATG  GAAGAGATCC  AGGGGTATGA  TGTGGAGTTT  180
181   GACCCACCCC  TGGAAAGCAA  GTATGAGTGC  CCCATCTGCT  TGATGGCATT  ACGGGAAGCA  240
241   GTGCAAACAC  CGTGTGGCCA  TAGGTTCTGC  AAAGCTTGCA  TCATCAAATC  AATAAGGGAT  300
301   GCAGGTCACA  AATGCCCAGT  TGACAATGAA  ATACTCCTGG  AAAATCAACT  GTTTCCTGAC  360
361   AATTTTGCAA  AACGGGAGAT  TCTTTCTCTG  ATGGTGAAGT  GTCCAAATGA  AGGTTGTTTG  420
421   CACAAAATGG  AACTTAGGCA  TCTTGAGGAT  CACCAATTAC  ACTGTGAGTT  TGCTCTCATG  480
481   AATTGTCTCC  AGTGCCAACG  TACCTTCCAA  AAATGCCAAC  TTAATATTCA  CATTCTCAAG  540
541   GAGTGCCCGA  GGAGACAGGT  TTCTTGCATG  AACTGTGCTG  CATTGATGGC  ATTCGAAGAT  600
601   AAAGAGATCC  ATGACCAGAA  CTGTCCTTTG  GCAAATGTCA  TCTGTGAATA  CTGCAATACC  660
661   ATGCTCATCA  GAGAACAGAT  GCCTAATCAT  TATGATCTAG  ACTGTCCTAC  AGCCCCAATT  720
721   CCATGCACAT  TCAGTACCTT  TGGTTGCCAT  GTAAAGATGC  AGAGGAATCA  CTTGGCACGC  780
781   CACCTACAGG  AGAATACCCA  GTCACACATG  AGAATGTTGG  GGCAGGCTGT  TCAGAGTTTA  840
841   AGCCTTGCTT  TAGCTCCTGT  ACCTCAGCGT  GATGTGCCGC  CGTATGATTC  TTCCTCGGTG  900
901   TCCCGGGTTT  CCAGCACGTG  TCACCCAGAG  GTTCAGAATT  TCCAAGAAAC  CATTCAGCAG  960
961   TTAGAGGGTC  GTCTTGTAAG  ACAAGACCAT  CAAATCCGAG  AGCTAACTGC  TAAAATGGAA  1020
1021  ACTCAGAGCA  TGCATGTAAG  TGAGCTCAAA  AGAAATATTC  GAACCCTTGA  GGACAAAGTT  1080
1081  GCTGAAATAG  AAGCACAGCA  GTGCAACGGG  ATCTACATCT  GGAAGATCGG  CAACTTCGGG  1140
1141  ATGCATCTGA  AATCTCAGGA  AGAAGAGAAA  CCTGTTGTCA  TTCACAGCCC  TGGATTCTAC  1200
1201  ACAGGGAAGC  CTGGGTACAA  ACTGTGCATG  CGCCTGCACC  TCCAGTTACC  AACTGCTCAG  1260
1261  CGCTGTGCTA  ATTATATATC  CCTCTTTGTC  CACACCATGC  AAGGAGAGTA  TGATAGCCAC  1320
1321  CTCCCCTGGC  CCTTCCAGGG  TACAATACGC  CTTGCGATTC  TTGATCAATC  TGAAGCGCCC  1380
1381  GTCAGGCAAA  ACCATGAAGA  GATAATGGAT  GCCAAACCAG  AGCTGCTTGC  CTTCCAGAGA  1440
1441  CCCACGATCC  CACGGAACCC  AAAAGGCTCC  TGCTCTGCTC  TCATGGGTTT  ACGTTACACA  1500
1501  GCGAAAATAA  AGGTTACGCA  GAGATCCTGT  TCTGCACAAT  TACCACTCCA  GCCACCTGCT  1560
1561  CATCACTGGT  TCCCAGTTCA  CTTCCTGGCA  AGTCGGTGTC  CTCTAGCTGC  TGCTGTGCCT  1620
1621  TCCACCCAGC  TCCTGAGAAT  CCTTGCAGCC  CCACCGTCTA  GGTTGGGAGC  CCTGCACTGC  1680
1681  TGCTGCTAA  1689

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Aim-1598Ailuropoda melanoleuca97.140.0 914
LLPS-Urm-2929Ursus maritimus97.140.0 913
LLPS-Mup-1968Mustela putorius furo95.710.0 900
LLPS-Fec-2592Felis catus94.890.0 895
LLPS-Eqc-3237Equus caballus93.870.0 888
LLPS-Cap-1083Cavia porcellus91.850.0 872
LLPS-Sus-2647Sus scrofa91.840.0 868
LLPS-Orc-3910Oryctolagus cuniculus90.390.0 858
LLPS-Ova-3370Ovis aries90.20.0 863
LLPS-Bot-2164Bos taurus90.20.0 858
LLPS-Poa-0051Pongo abelii89.980.0 842
LLPS-Caj-3348Callithrix jacchus89.780.0 850
LLPS-Gog-1366Gorilla gorilla89.780.0 840
LLPS-Aon-1307Aotus nancymaae89.780.0 850
LLPS-Pap-0671Pan paniscus89.780.0 840
LLPS-Pat-2487Pan troglodytes89.780.0 840
LLPS-Fud-1686Fukomys damarensis89.610.0 862
LLPS-Hos-0351Homo sapiens89.370.0 838
LLPS-Nol-4653Nomascus leucogenys89.370.0 837
LLPS-Cea-2533Cercocebus atys89.160.0 835
LLPS-Myl-2066Myotis lucifugus89.160.0 842
LLPS-Paa-1307Papio anubis89.160.0 835
LLPS-Mal-2228Mandrillus leucophaeus89.160.0 835
LLPS-Otg-1717Otolemur garnettii89.00.0 845
LLPS-Chs-1115Chlorocebus sabaeus88.960.0 834
LLPS-Maf-2988Macaca fascicularis88.960.0 834
LLPS-Rhb-3093Rhinopithecus bieti88.960.0 832
LLPS-Man-2052Macaca nemestrina88.960.0 834
LLPS-Mam-1949Macaca mulatta88.960.0 834
LLPS-Ict-0637Ictidomys tridecemlineatus88.750.0 848
LLPS-Dio-1814Dipodomys ordii88.340.0 831
LLPS-Loa-0287Loxodonta africana88.140.0 829
LLPS-Mum-2736Mus musculus85.280.0 797
LLPS-Cas-0929Carlito syrichta85.280.0 815
LLPS-Ran-1650Rattus norvegicus84.050.0 789
LLPS-Mea-2593Mesocricetus auratus83.770.0 803
LLPS-Sah-0008Sarcophilus harrisii81.60.0 777
LLPS-Ora-1381Ornithorhynchus anatinus80.820.0 799
LLPS-Mod-3218Monodelphis domestica80.240.0 763
LLPS-Fia-2872Ficedula albicollis75.420.0 654
LLPS-Gaga-1541Gallus gallus74.850.0 721
LLPS-Meg-2474Meleagris gallopavo74.440.0 721
LLPS-Tag-1630Taeniopygia guttata74.240.0 723
LLPS-Anp-0354Anas platyrhynchos73.350.0 712
LLPS-Anc-0308Anolis carolinensis72.250.0 673
LLPS-Pes-1619Pelodiscus sinensis71.340.0 709
LLPS-Lac-1857Latimeria chalumnae70.130.0 650
LLPS-Xet-2932Xenopus tropicalis68.130.0 638
LLPS-Leo-0071Lepisosteus oculatus60.780.0 558
LLPS-Scf-1150Scleropages formosus58.690.0 528
LLPS-Dar-1639Danio rerio58.183e-177 519
LLPS-Ten-3096Tetraodon nigroviridis57.994e-175 514
LLPS-Scm-2031Scophthalmus maximus57.924e-180 528
LLPS-Asm-2861Astyanax mexicanus57.373e-180 527
LLPS-Orl-3182Oryzias latipes57.143e-180 528
LLPS-Icp-0145Ictalurus punctatus56.981e-178 523
LLPS-Xim-2309Xiphophorus maculatus56.922e-178 523
LLPS-Orn-3959Oreochromis niloticus56.770.0 543
LLPS-Pof-2113Poecilia formosa56.481e-175 516
LLPS-Tar-0042Takifugu rubripes56.221e-175 516
LLPS-Gaa-0665Gasterosteus aculeatus55.431e-177 521
LLPS-Drm-1133Drosophila melanogaster50.06e-0755.8
LLPS-Hea-0820Helianthus annuus46.34e-0652.0
LLPS-Mae-0114Manihot esculenta43.082e-0655.1
LLPS-Cis-0461Ciona savignyi42.996e-50 178
LLPS-Brr-0481Brassica rapa40.38e-0653.1
LLPS-Gor-0503Gossypium raimondii39.684e-0653.9
LLPS-Cym-0921Cyanidioschyzon merolae39.473e-0654.3
LLPS-Met-1885Medicago truncatula38.984e-0653.9
LLPS-Php-2403Physcomitrella patens38.247e-0653.1
LLPS-Amt-1173Amborella trichopoda37.56e-0653.1
LLPS-Tut-1912Tursiops truncatus33.338e-0857.4
LLPS-Fuv-0840Fusarium verticillioides31.01e-2099.8
LLPS-Mao-1349Magnaporthe oryzae30.695e-1582.0
LLPS-Fuo-0224Fusarium oxysporum30.53e-1995.5
LLPS-Dac-0629Daucus carota29.518e-0962.4
LLPS-Osl-0449Ostreococcus lucimarinus29.034e-0653.9
LLPS-Map-1088Magnaporthe poae28.512e-1170.9
LLPS-Miv-0911Microbotryum violaceum28.125e-1272.4
LLPS-Beb-0195Beauveria bassiana27.363e-1788.6
LLPS-Spr-0943Sporisorium reilianum26.898e-1581.6
LLPS-Cii-0264Ciona intestinalis26.574e-40 156
LLPS-Usm-0921Ustilago maydis26.21e-1480.9
LLPS-Cogr-1284Colletotrichum graminicola26.056e-1684.7
LLPS-Ere-0543Erinaceus europaeus25.02e-29 124
LLPS-Lem-1262Leptosphaeria maculans24.784e-0653.9
LLPS-Scs-0628Sclerotinia sclerotiorum24.354e-1066.6
LLPS-Cae-0411Caenorhabditis elegans24.074e-23 106
LLPS-Gag-0753Gaeumannomyces graminis23.171e-0655.5