LLPS-Cae-1915
pas-7

▼ OVERVIEW


Status: Unreviewed
Protein Name: Proteasome subunit alpha type-3; Proteasome subunit alpha 7
Gene Name: pas-7, ZK945.2
Ensembl Gene: WBGene00003928
Ensembl Protein: ZK945.2.2
Organism: Caenorhabditis elegans
Taxa ID: 6239
LLPS Type: Others


▼ PROPERTY



——— Disorder propensity (calculated by IUPred2A)

▼ Classification


Condensates:
CondensateEvidenceOrthologs
Nuclear specklePredicted from orthologs(View)

▼ FUNCTION


The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity).

▼ CROSS REFERENCE


DatabaseNucleotide IDProtein ID
EnsemblZK945.2.2ZK945.2.2
EnsemblZK945.2.1ZK945.2.1
UniProtQ09583, PSA3_CAEEL
GeneBankZ48544CAA88436.2
RefSeqNM_063776.3NP_496177.2
Entrez174571

▼ SEQUENCE


Protein Sequence (FASTA)
1     MSSIGTGYDL  AASTFSPDGR  IFQVEYAQKA  VDNAGTMIAI  RGKNGVVVVA  DKLISSKLYT  60
61    DNANPRMFNV  NDNVGVAVAG  NYPDGFALKN  YAYGEAMKWL  KDYREPMPIQ  NIANSVAEYI  120
121   HIHTLGISRP  FGAGAFFMSW  NKQTGGRLFL  VEPSGLNYEY  KAWAVGKHRQ  AAKAEIEKLK  180
181   IEELDVNQLV  KEAARIIMVV  RDENKDKNVQ  IEMGWVGEQT  NGKYEEVPSE  VVTAAEEWAI  240
241   AKLDEDDMDD  250
Nucleotide CDS Sequence (FASTA)
1     ATGAGTTCAA  TCGGTACCGG  CTACGATCTC  GCCGCCTCTA  CTTTTTCTCC  TGATGGCAGA  60
61    ATTTTCCAAG  TCGAGTACGC  TCAAAAGGCT  GTCGACAATG  CAGGAACAAT  GATTGCAATT  120
121   CGTGGCAAGA  ACGGAGTTGT  GGTCGTTGCT  GACAAGCTGA  TCTCTTCCAA  ACTTTACACT  180
181   GATAACGCTA  ATCCAAGAAT  GTTTAACGTG  AACGACAATG  TTGGTGTCGC  AGTTGCTGGA  240
241   AACTATCCAG  ATGGTTTCGC  TCTGAAGAAC  TATGCTTACG  GAGAAGCAAT  GAAGTGGCTC  300
301   AAAGACTACC  GTGAGCCAAT  GCCGATTCAG  AATATTGCTA  ACTCAGTTGC  TGAGTACATT  360
361   CACATTCACA  CTCTCGGCAT  TAGTCGTCCG  TTTGGAGCAG  GAGCCTTCTT  CATGTCATGG  420
421   AACAAACAAA  CTGGAGGACG  TCTTTTCCTT  GTGGAGCCAT  CAGGTCTAAA  CTATGAATAC  480
481   AAGGCATGGG  CTGTCGGAAA  ACATCGCCAA  GCCGCAAAAG  CTGAGATTGA  GAAGCTGAAG  540
541   ATCGAGGAGC  TGGATGTGAA  TCAACTCGTG  AAGGAAGCTG  CTCGAATCAT  TATGGTGGTG  600
601   CGTGACGAGA  ACAAGGATAA  AAACGTTCAA  ATCGAAATGG  GATGGGTCGG  TGAGCAGACG  660
661   AACGGAAAGT  ACGAAGAAGT  TCCAAGCGAG  GTTGTCACTG  CTGCCGAGGA  ATGGGCTATT  720
721   GCCAAGCTTG  ACGAGGACGA  CATGGACGAT  TGA  753

▼ KEYWORD


ID
Family
Complete proteome
Cytoplasm
Hydrolase
Nucleus
Protease
Proteasome
Reference proteome
Threonine protease

▼ GENE ONTOLOGY


ID
Classification
Description
Cellular Component
Cytoplasm
Cellular Component
Nucleus
Cellular Component
Proteasome core complex
Cellular Component
Proteasome core complex, alpha-subunit complex
Cellular Component
Synapse
Molecular Function
Endopeptidase activity
Molecular Function
Identical protein binding
Molecular Function
Threonine-type endopeptidase activity
Biological Process
Proteasomal protein catabolic process
Biological Process
Proteasomal ubiquitin-independent protein catabolic process
Biological Process
Proteasome-mediated ubiquitin-dependent protein catabolic process

▼ KEGG



▼ ORTHOLOGY


DrLLPS IDOrganismIdentityE-valueScore
LLPS-Leo-3785Lepisosteus oculatus50.835e-63 204
LLPS-Tar-1809Takifugu rubripes50.421e-61 202
LLPS-Orl-3822Oryzias latipes50.428e-63 204
LLPS-Gaa-3011Gasterosteus aculeatus50.05e-63 204
LLPS-Gaga-1561Gallus gallus49.81e-64 208
LLPS-Fia-3501Ficedula albicollis49.88e-65 209
LLPS-Orn-3329Oreochromis niloticus49.584e-63 204
LLPS-Dar-2957Danio rerio49.588e-62 201
LLPS-Tra-1275Triticum aestivum49.579e-58 191
LLPS-Bot-4114Bos taurus49.41e-63 206
LLPS-Sah-2592Sarcophilus harrisii49.47e-64 206
LLPS-Pes-2392Pelodiscus sinensis49.47e-64 206
LLPS-Mod-0955Monodelphis domestica49.41e-63 206
LLPS-Icp-3907Ictalurus punctatus49.177e-62 201
LLPS-Asm-0454Astyanax mexicanus49.174e-61 199
LLPS-Fec-3203Felis catus49.172e-60 198
LLPS-Tru-1561Triticum urartu49.141e-56 187
LLPS-Ran-3447Rattus norvegicus49.06e-63 204
LLPS-Ova-4460Ovis aries49.02e-63 205
LLPS-Mal-3069Mandrillus leucophaeus49.01e-63 206
LLPS-Paa-4098Papio anubis49.01e-63 206
LLPS-Gog-3512Gorilla gorilla49.01e-63 206
LLPS-Caj-1352Callithrix jacchus49.01e-63 206
LLPS-Fud-3260Fukomys damarensis49.02e-63 206
LLPS-Chs-2972Chlorocebus sabaeus49.01e-63 206
LLPS-Maf-4075Macaca fascicularis49.01e-63 206
LLPS-Aon-0926Aotus nancymaae49.07e-64 206
LLPS-Cea-1081Cercocebus atys49.01e-63 206
LLPS-Nol-4628Nomascus leucogenys49.01e-63 206
LLPS-Poa-2480Pongo abelii49.01e-63 206
LLPS-Orc-4013Oryctolagus cuniculus49.01e-61 203
LLPS-Hos-1142Homo sapiens49.01e-63 206
LLPS-Pat-4143Pan troglodytes49.01e-63 206
LLPS-Pap-3978Pan paniscus49.01e-63 206
LLPS-Man-1021Macaca nemestrina49.01e-63 206
LLPS-Pof-2203Poecilia formosa48.975e-61 199
LLPS-Xet-0178Xenopus tropicalis48.774e-60 197
LLPS-Scf-1841Scleropages formosus48.756e-61 199
LLPS-Brd-0608Brachypodium distachyon48.714e-57 189
LLPS-Aim-2237Ailuropoda melanoleuca48.611e-62 203
LLPS-Mup-3672Mustela putorius furo48.611e-62 203
LLPS-Mum-4381Mus musculus48.615e-63 204
LLPS-Sus-2460Sus scrofa48.611e-62 203
LLPS-Cas-1034Carlito syrichta48.617e-63 204
LLPS-Anc-2538Anolis carolinensis48.612e-63 205
LLPS-Ict-4659Ictidomys tridecemlineatus48.618e-63 204
LLPS-Cap-4336Cavia porcellus48.618e-63 204
LLPS-Eqc-4570Equus caballus48.619e-63 204
LLPS-Caf-1219Canis familiaris48.619e-63 204
LLPS-Otg-0879Otolemur garnettii48.617e-63 204
LLPS-Urm-0817Ursus maritimus48.611e-62 203
LLPS-Loa-3282Loxodonta africana48.618e-63 204
LLPS-Viv-1547Vitis vinifera48.485e-54 181
LLPS-Phv-1199Phaseolus vulgaris48.471e-54 182
LLPS-Rhb-3574Rhinopithecus bieti48.412e-61 200
LLPS-Tag-2237Taeniopygia guttata48.361e-59 195
LLPS-Hov-0437Hordeum vulgare48.283e-56 186
LLPS-Myl-1429Myotis lucifugus48.215e-62 202
LLPS-Cus-2156Cucumis sativus48.054e-55 184
LLPS-Hea-2161Helianthus annuus48.032e-54 182
LLPS-Glm-2455Glycine max48.031e-53 180
LLPS-Ten-3806Tetraodon nigroviridis47.956e-59 194
LLPS-Anp-0609Anas platyrhynchos47.952e-58 192
LLPS-Prp-1465Prunus persica47.642e-53 179
LLPS-Sot-0151Solanum tuberosum47.623e-54 182
LLPS-Nia-0544Nicotiana attenuata47.621e-54 182
LLPS-Lep-1311Leersia perrieri47.62e-58 192
LLPS-Orbr-0193Oryza brachyantha47.62e-58 192
LLPS-Asg-1168Ashbya gossypii47.547e-51 174
LLPS-Mam-0285Macaca mulatta47.542e-58 192
LLPS-Meg-2906Meleagris gallopavo47.542e-56 187
LLPS-Met-2020Medicago truncatula47.21e-58 193
LLPS-Via-2356Vigna angularis47.22e-55 185
LLPS-Pug-1068Puccinia graminis46.641e-55 185
LLPS-Xim-4147Xiphophorus maculatus46.614e-58 193
LLPS-Usm-1526Ustilago maydis46.613e-57 189
LLPS-Sol-2254Solanum lycopersicum46.42e-55 185
LLPS-Pot-2194Populus trichocarpa46.43e-56 187
LLPS-Coc-0281Corchorus capsularis46.354e-53 178
LLPS-Tum-1347Tuber melanosporum46.222e-51 175
LLPS-Mua-2261Musa acuminata46.02e-56 187
LLPS-Mae-1189Manihot esculenta46.03e-56 186
LLPS-Lac-0146Latimeria chalumnae46.06e-57 189
LLPS-Dac-1069Daucus carota45.924e-52 176
LLPS-Chr-1682Chlamydomonas reinhardtii45.828e-53 178
LLPS-Cii-2248Ciona intestinalis45.829e-58 191
LLPS-Sei-1463Setaria italica45.696e-54 181
LLPS-Thc-1878Theobroma cacao45.62e-55 185
LLPS-Amt-1443Amborella trichopoda45.63e-55 184
LLPS-Asni-1591Aspergillus niger45.569e-53 178
LLPS-Dio-4368Dipodomys ordii45.422e-53 179
LLPS-Cis-1910Ciona savignyi45.421e-57 190
LLPS-Spr-0889Sporisorium reilianum45.424e-57 189
LLPS-Gor-0250Gossypium raimondii45.429e-54 180
LLPS-Sob-0872Sorghum bicolor45.269e-52 175
LLPS-Orgl-2173Oryza glumaepatula45.22e-56 187
LLPS-Php-2512Physcomitrella patens45.22e-52 177
LLPS-Orni-1212Oryza nivara45.24e-55 186
LLPS-Ori-1343Oryza indica45.22e-56 187
LLPS-Org-2121Oryza glaberrima45.22e-56 187
LLPS-Orm-1800Oryza meridionalis45.23e-56 187
LLPS-Orr-2347Oryza rufipogon45.22e-56 187
LLPS-Ors-2133Oryza sativa45.22e-56 187
LLPS-Orp-1745Oryza punctata45.22e-56 187
LLPS-Sem-1758Selaginella moellendorffii45.063e-50 171
LLPS-Orb-2264Oryza barthii44.764e-53 181
LLPS-Abg-0268Absidia glauca44.631e-46 167
LLPS-Scj-0520Schizosaccharomyces japonicus44.051e-53 181
LLPS-Drm-2187Drosophila melanogaster43.821e-52 177
LLPS-Put-0597Puccinia triticina43.89e-53 178
LLPS-Brn-1070Brassica napus43.63e-53 179
LLPS-Bro-1282Brassica oleracea43.69e-53 177
LLPS-Brr-2527Brassica rapa43.63e-53 179
LLPS-Mel-1182Melampsora laricipopulina43.593e-50 171
LLPS-Kop-0320Komagataella pastoris43.579e-48 165
LLPS-Asn-0868Aspergillus nidulans43.549e-50 171
LLPS-Miv-1100Microbotryum violaceum43.36e-51 173
LLPS-Scm-3188Scophthalmus maximus43.152e-28 111
LLPS-Crn-1355Cryptococcus neoformans43.043e-47 164
LLPS-Scp-1208Schizosaccharomyces pombe43.039e-49 167
LLPS-Asc-1621Aspergillus clavatus42.82e-49 170
LLPS-Art-2127Arabidopsis thaliana42.84e-51 176
LLPS-Zyt-1426Zymoseptoria tritici42.75e-50 172
LLPS-Yal-1150Yarrowia lipolytica42.698e-49 167
LLPS-Gag-1367Gaeumannomyces graminis42.553e-48 167
LLPS-Dos-0198Dothistroma septosporum42.553e-51 175
LLPS-Scc-1091Schizosaccharomyces cryophilus42.52e-46 161
LLPS-Mao-1358Magnaporthe oryzae42.442e-48 167
LLPS-Arl-0788Arabidopsis lyrata42.42e-52 177
LLPS-Coo-1336Colletotrichum orbiculare42.399e-47 163
LLPS-Zem-0015Zea mays42.253e-53 179
LLPS-Sac-1579Saccharomyces cerevisiae42.215e-44 156
LLPS-Asf-0692Aspergillus flavus42.187e-50 172
LLPS-Pyt-1393Pyrenophora teres42.037e-50 171
LLPS-Pytr-1468Pyrenophora triticirepentis42.031e-49 171
LLPS-Cog-1008Colletotrichum gloeosporioides42.037e-46 162
LLPS-Aso-1463Aspergillus oryzae41.828e-50 171
LLPS-Cogr-1086Colletotrichum graminicola41.671e-45 160
LLPS-Chc-0202Chondrus crispus41.636e-50 171
LLPS-Trr-1569Trichoderma reesei41.183e-46 162
LLPS-Fus-0371Fusarium solani41.033e-46 162
LLPS-Lem-0901Leptosphaeria maculans40.963e-47 166
LLPS-Phn-1263Phaeosphaeria nodorum40.891e-45 160
LLPS-Nec-1424Neurospora crassa40.888e-47 164
LLPS-Trv-0953Trichoderma virens40.812e-45 160
LLPS-Mea-0109Mesocricetus auratus40.482e-29 115
LLPS-Asfu-0774Aspergillus fumigatus40.242e-37 139
LLPS-Ast-1132Aspergillus terreus40.211e-45 160
LLPS-Nef-0582Neosartorya fischeri40.161e-36 136
LLPS-Blg-1273Blumeria graminis40.074e-48 167
LLPS-Fuv-0723Fusarium verticillioides40.072e-45 160
LLPS-Fuo-0641Fusarium oxysporum40.072e-45 160
LLPS-Ved-0181Verticillium dahliae40.03e-45 159
LLPS-Beb-0973Beauveria bassiana39.786e-43 153
LLPS-Cym-0990Cyanidioschyzon merolae39.51e-43 154
LLPS-Vir-2044Vigna radiata38.728e-36 134
LLPS-Gas-1033Galdieria sulphuraria38.651e-45 160
LLPS-Osl-1396Ostreococcus lucimarinus38.332e-40 145