• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Bro-2415
106336294

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Nicalin
Gene Name: 106336294
Ensembl Gene: Bo3g123550
Ensembl Protein: Bo3g123550.1
Organism: Brassica oleracea
Taxa ID: 109376
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
NucleolusPredicted from orthologs(View)

▼ FUNCTION

May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblBo3g123550.1Bo3g123550.1
UniProtA0A0D3BGY1, A0A0D3BGY1_BRAOL
RefSeqXM_013775082.1XP_013630536.1

▼ SEQUENCE

Protein Sequence (FASTA)
1     MADEKKSKQR  DGSMVFESMY  PLLALMLILV  ACVDLCDAAT  VVDVYRLVQY  DISGVPFGSR  60
61    FSSLNHHAAS  LSFQRGADLS  RSVLILPLRE  LDLGFLQDYI  SQKQSLGGLL  ILLPQTLRPG  120
121   NIGGGSVLSE  TQGFRKLLAQ  LEKLLVHGNI  PFPVYFAFEN  EETDAMLADV  KKNDALGQQA  180
181   TATTGGYKLV  ISVSEPRKIA  SPTITNIQGW  LPGSRAEGDS  NQLPTIAIVA  SYDTFGAAPA  240
241   LSVGSDSNGS  GVVALLEVAR  LFSTLYSNPK  TRGRYNLLFA  LTSGGPYNYE  GTQKWLKSLD  300
301   QRMRESIDYA  ICLNSVGSWD  NELLVHVSKP  PDNAYIKQIF  EGFSNVAEDL  GFQVALKHKK  360
361   INISNSRVAW  EHEQFSRLRV  TAATLSELPT  PPELLESAGS  LSDTRQLVHD  DAIIKGVKLV  420
421   AESLARHIYG  HQRKDIKIFA  DDSSLAVNPF  NVRSWLDLLS  QTPRVAPFLS  KSEPLIMALK  480
481   KELEDYTAEV  SVQHESLDGI  FTFYDSTKAS  LNIYQVASVT  FDLLLLLVLG  SYLIVLFSFL  540
541   VITTRGVDDL  ISLFRRPPSR  KVKMV  565
Nucleotide CDS Sequence (FASTA)
1     ATGGCGGACG  AAAAGAAGTC  GAAGCAGAGA  GATGGGTCCA  TGGTCTTCGA  GTCCATGTAT  60
61    CCACTCCTCG  CCCTCATGCT  CATCCTCGTC  GCTTGCGTCG  ATCTGTGCGA  CGCGGCCACT  120
121   GTTGTAGATG  TTTACCGTCT  CGTCCAATAT  GACATCTCCG  GCGTTCCTTT  CGGCTCTCGT  180
181   TTCTCCTCCC  TCAACCACCA  CGCCGCCTCC  CTCAGCTTCC  AGCGCGGCGC  CGATCTATCT  240
241   CGCTCTGTAC  TTATCCTCCC  ACTCCGCGAA  CTCGATCTCG  GATTCCTTCA  GGATTACATC  300
301   TCACAGAAGC  AGTCTCTTGG  GGGATTGTTG  ATTTTGCTTC  CCCAGACGTT  AAGACCTGGC  360
361   AACATTGGTG  GTGGAAGTGT  TCTCTCTGAA  ACCCAAGGGT  TCAGGAAATT  ATTAGCACAG  420
421   CTTGAGAAAT  TACTTGTCCA  CGGCAACATA  CCTTTTCCTG  TGTACTTTGC  ATTTGAGAAT  480
481   GAAGAGACTG  ATGCTATGTT  GGCTGATGTT  AAGAAAAATG  ATGCACTTGG  TCAGCAAGCT  540
541   ACTGCCACCA  CAGGCGGATA  TAAGCTTGTT  ATCTCTGTAT  CCGAGCCTAG  GAAAATTGCA  600
601   TCTCCCACCA  TCACTAATAT  TCAGGGATGG  CTTCCAGGAT  CAAGAGCAGA  AGGAGATTCC  660
661   AACCAGCTTC  CAACAATTGC  TATTGTTGCA  TCCTATGATA  CCTTCGGAGC  AGCTCCTGCA  720
721   CTATCGGTGG  GAAGTGATAG  CAATGGAAGT  GGGGTCGTGG  CGCTTCTTGA  AGTAGCTAGA  780
781   CTATTTTCCA  CTCTTTATTC  AAATCCCAAG  ACAAGGGGAA  GGTACAATTT  ACTTTTTGCA  840
841   CTGACATCTG  GTGGACCCTA  CAACTACGAA  GGGACTCAAA  AGTGGCTGAA  GAGCCTTGAT  900
901   CAGCGGATGC  GTGAGAGCAT  TGATTATGCC  ATTTGCTTGA  ACAGTGTTGG  CTCTTGGGAC  960
961   AATGAATTAT  TGGTTCACGT  GTCAAAGCCT  CCAGATAACG  CCTATATAAA  ACAAATATTT  1020
1021  GAGGGCTTCT  CTAATGTGGC  AGAAGACTTG  GGTTTTCAAG  TTGCTCTGAA  GCACAAGAAG  1080
1081  ATTAATATCT  CTAATTCACG  TGTTGCTTGG  GAGCATGAAC  AATTTTCACG  ACTCAGAGTA  1140
1141  ACTGCAGCCA  CTCTATCCGA  ACTTCCGACT  CCACCTGAGT  TACTGGAAAG  TGCTGGAAGT  1200
1201  CTGTCTGACA  CAAGGCAACT  TGTGCATGAT  GATGCCATCA  TTAAGGGTGT  CAAGTTGGTG  1260
1261  GCTGAAAGCC  TTGCTAGACA  TATCTATGGT  CACCAAAGAA  AAGACATCAA  GATTTTTGCA  1320
1321  GATGACAGTA  GTTTGGCTGT  AAATCCCTTT  AATGTGAGAT  CATGGTTGGA  TCTTTTGTCA  1380
1381  CAAACTCCTC  GGGTGGCACC  GTTTCTCTCA  AAGAGTGAAC  CACTAATCAT  GGCTCTGAAG  1440
1441  AAGGAACTAG  AGGATTATAC  TGCTGAAGTG  AGTGTTCAAC  ATGAATCTTT  AGATGGAATT  1500
1501  TTCACCTTTT  ACGACTCAAC  AAAGGCTAGC  CTTAACATAT  ACCAGGTGGC  GAGTGTAACA  1560
1561  TTCGACTTGC  TCTTGCTTCT  GGTGTTAGGA  TCATACTTAA  TAGTGCTTTT  CAGCTTCCTC  1620
1621  GTCATCACAA  CTCGGGGTGT  GGATGACTTA  ATAAGCTTAT  TCCGCCGGCC  TCCTTCCCGG  1680
1681  AAAGTGAAAA  TGGTTTGA  1698

▼ KEYWORD

ID
Family
Complete proteome
Membrane
Reference proteome
Signal
Transmembrane
Transmembrane helix

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Integral component of membrane
Biological Process
Protein processing
Biological Process
Regulation of signal transduction

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Brn-3372Brassica napus100.00.01043
LLPS-Brr-0414Brassica rapa97.350.01012
LLPS-Arl-2744Arabidopsis lyrata93.970.0 986
LLPS-Art-0511Arabidopsis thaliana93.790.0 983
LLPS-Vir-0634Vigna radiata81.163e-57 204
LLPS-Tru-1153Triticum urartu78.053e-23 108
LLPS-Thc-2357Theobroma cacao76.240.0 794
LLPS-Gor-2181Gossypium raimondii76.050.0 775
LLPS-Prp-2095Prunus persica75.970.0 779
LLPS-Coc-2280Corchorus capsularis75.350.0 782
LLPS-Mae-1300Manihot esculenta74.420.0 784
LLPS-Viv-1971Vitis vinifera73.520.0 761
LLPS-Cus-2004Cucumis sativus73.50.0 736
LLPS-Pot-1772Populus trichocarpa73.260.0 765
LLPS-Dac-1899Daucus carota72.780.0 726
LLPS-Nia-1618Nicotiana attenuata72.370.0 724
LLPS-Mua-2547Musa acuminata72.340.0 714
LLPS-Sol-2476Solanum lycopersicum71.630.0 721
LLPS-Via-0082Vigna angularis71.560.0 742
LLPS-Phv-2394Phaseolus vulgaris71.40.0 738
LLPS-Glm-1182Glycine max71.020.0 734
LLPS-Met-0924Medicago truncatula69.950.0 736
LLPS-Amt-2180Amborella trichopoda69.620.0 724
LLPS-Hea-1072Helianthus annuus69.60.0 724
LLPS-Ori-2248Oryza indica69.230.0 585
LLPS-Sei-1096Setaria italica68.420.0 650
LLPS-Orgl-1342Oryza glumaepatula68.160.0 645
LLPS-Orni-0798Oryza nivara68.160.0 646
LLPS-Orb-1277Oryza barthii68.050.0 640
LLPS-Orr-1905Oryza rufipogon67.980.0 644
LLPS-Ors-2359Oryza sativa67.980.0 644
LLPS-Orbr-1355Oryza brachyantha67.920.0 631
LLPS-Brd-1990Brachypodium distachyon67.540.0 647
LLPS-Hov-0790Hordeum vulgare66.920.0 644
LLPS-Tra-1084Triticum aestivum66.730.0 638
LLPS-Lep-1143Leersia perrieri66.360.0 627
LLPS-Sob-0099Sorghum bicolor65.820.0 653
LLPS-Zem-0901Zea mays65.390.0 659
LLPS-Sem-1745Selaginella moellendorffii60.370.0 557
LLPS-Php-1503Physcomitrella patens58.860.0 564
LLPS-Orm-1342Oryza meridionalis52.173e-0753.1
LLPS-Dar-2965Danio rerio34.352e-58 210
LLPS-Mam-2515Macaca mulatta33.591e-47 178
LLPS-Anc-3549Anolis carolinensis33.338e-44 167
LLPS-Ova-2712Ovis aries33.332e-55 201
LLPS-Leo-2225Lepisosteus oculatus33.157e-60 214
LLPS-Fec-2863Felis catus33.071e-56 205
LLPS-Bot-2713Bos taurus33.04e-57 206
LLPS-Ran-2864Rattus norvegicus32.872e-56 205
LLPS-Dio-0955Dipodomys ordii32.813e-56 204
LLPS-Ten-2646Tetraodon nigroviridis32.787e-57 206
LLPS-Caf-1594Canis familiaris32.754e-57 206
LLPS-Icp-4008Ictalurus punctatus32.712e-60 215
LLPS-Ict-4568Ictidomys tridecemlineatus32.614e-55 201
LLPS-Nol-4044Nomascus leucogenys32.619e-48 179
LLPS-Scf-3603Scleropages formosus32.532e-60 215
LLPS-Xet-2331Xenopus tropicalis32.482e-56 204
LLPS-Mea-3841Mesocricetus auratus32.484e-56 204
LLPS-Mum-3059Mus musculus32.485e-57 206
LLPS-Otg-3983Otolemur garnettii32.414e-55 201
LLPS-Myl-3038Myotis lucifugus32.419e-56 202
LLPS-Sus-1526Sus scrofa32.413e-56 204
LLPS-Asm-1257Astyanax mexicanus32.379e-58 209
LLPS-Lac-3572Latimeria chalumnae32.364e-57 205
LLPS-Cas-1419Carlito syrichta32.348e-1065.1
LLPS-Gaga-0798Gallus gallus32.313e-58 209
LLPS-Gaa-1598Gasterosteus aculeatus32.311e-54 199
LLPS-Tag-2666Taeniopygia guttata32.282e-58 210
LLPS-Scm-1461Scophthalmus maximus32.271e-55 202
LLPS-Cap-0509Cavia porcellus32.29e-54 197
LLPS-Meg-1584Meleagris gallopavo32.162e-48 181
LLPS-Tar-2963Takifugu rubripes32.162e-58 210
LLPS-Maf-0425Macaca fascicularis32.144e-54 198
LLPS-Hos-2968Homo sapiens32.085e-56 203
LLPS-Xim-1892Xiphophorus maculatus32.055e-56 204
LLPS-Orl-2820Oryzias latipes31.958e-56 203
LLPS-Fud-2935Fukomys damarensis31.95e-31 129
LLPS-Pat-1812Pan troglodytes31.883e-55 201
LLPS-Paa-1013Papio anubis31.883e-55 201
LLPS-Chs-3971Chlorocebus sabaeus31.883e-55 201
LLPS-Aon-0908Aotus nancymaae31.882e-55 201
LLPS-Pof-3123Poecilia formosa31.774e-56 204
LLPS-Pap-3287Pan paniscus31.762e-52 194
LLPS-Fia-3336Ficedula albicollis31.752e-47 179
LLPS-Gog-1765Gorilla gorilla31.744e-53 195
LLPS-Aim-3694Ailuropoda melanoleuca31.696e-48 181
LLPS-Poa-4079Pongo abelii31.662e-43 167
LLPS-Mod-0312Monodelphis domestica31.624e-54 198
LLPS-Mup-4566Mustela putorius furo31.381e-49 185
LLPS-Anp-2059Anas platyrhynchos31.344e-48 180
LLPS-Sah-2870Sarcophilus harrisii31.292e-49 185
LLPS-Rhb-3872Rhinopithecus bieti31.191e-51 191
LLPS-Man-3938Macaca nemestrina31.141e-47 179
LLPS-Pes-2575Pelodiscus sinensis31.082e-47 178
LLPS-Cii-2309Ciona intestinalis31.071e-57 208
LLPS-Orn-2784Oreochromis niloticus31.052e-55 202
LLPS-Ora-3381Ornithorhynchus anatinus30.773e-49 184
LLPS-Cae-1852Caenorhabditis elegans30.362e-1996.3
LLPS-Mal-2136Mandrillus leucophaeus29.725e-22 102
LLPS-Caj-4096Callithrix jacchus29.626e-49 185
LLPS-Cea-4007Cercocebus atys29.012e-35 143
LLPS-Eqc-2270Equus caballus28.521e-48 184
LLPS-Loa-2224Loxodonta africana26.131e-23 108
LLPS-Drm-2324Drosophila melanogaster26.083e-29 125