LLPS-Bro-1614
106306802
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | dCTP pyrophosphatase 1 |
| Gene Name: | 106306802 |
| Ensembl Gene: | Bo7g031080 |
| Ensembl Protein: | Bo7g031080.1 |
| Organism: | Brassica oleracea |
| Taxa ID: | 109376 |
| LLPS Type: | Client |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Stress granule | Predicted from orthologs | (View) |
▼ FUNCTION
| Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | Bo7g031080.1 | Bo7g031080.1 |
| UniProt | A0A0D3D4S0, A0A0D3D4S0_BRAOL | |
| RefSeq | XM_013743556.1 | XP_013599010.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MDMGEEKEVV SLGTLSKKMD DFAKARDWEK YHSPRNLLLA MVGEVGELSE IFQWRGEVER 60 61 GLPDWKEEDK VHLGEELSDV LLYLVRLSDV CGVDLGKAAL RKLELNAIKY PAPKQTDHCV 120 121 GEHSSDNTKL TEDN 134 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGACATGG GGGAAGAGAA GGAAGTAGTT TCTCTGGGAA CTCTGAGTAA GAAGATGGAT 60 61 GATTTTGCAA AGGCTAGAGA TTGGGAGAAG TATCACAGCC CAAGGAACCT CCTTTTAGCC 120 121 ATGGTGGGTG AAGTGGGAGA GTTATCAGAG ATATTCCAAT GGAGAGGGGA AGTGGAAAGA 180 181 GGACTTCCGG ATTGGAAAGA AGAAGACAAA GTTCATCTTG GTGAAGAATT ATCAGATGTG 240 241 TTGTTGTATC TGGTGAGGCT TTCTGATGTT TGTGGTGTCG ATTTGGGCAA GGCCGCTCTG 300 301 CGGAAACTCG AGCTCAATGC CATTAAGTAC CCAGCACCCA AACAGACTGA TCATTGTGTT 360 361 GGTGAACATT CAAGCGACAA TACTAAGTTG ACCGAAGATA ATTAA 405 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Molecular Function | Metal ion binding | |
Molecular Function | Nucleoside-triphosphate diphosphatase activity | |
Biological Process | Nucleoside triphosphate catabolic process |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Brr-2922 | Brassica rapa | 99.25 | 6e-93 | 271 |
| LLPS-Brn-1141 | Brassica napus | 97.76 | 3e-91 | 267 |
| LLPS-Arl-1879 | Arabidopsis lyrata | 88.28 | 3e-74 | 224 |
| LLPS-Art-2854 | Arabidopsis thaliana | 85.82 | 6e-75 | 226 |
| LLPS-Pot-1945 | Populus trichocarpa | 84.31 | 8e-56 | 178 |
| LLPS-Vir-2089 | Vigna radiata | 84.04 | 2e-53 | 171 |
| LLPS-Glm-2406 | Glycine max | 81.55 | 4e-57 | 181 |
| LLPS-Coc-1865 | Corchorus capsularis | 81.31 | 4e-57 | 181 |
| LLPS-Via-1086 | Vigna angularis | 80.58 | 8e-56 | 177 |
| LLPS-Gor-0231 | Gossypium raimondii | 80.37 | 2e-55 | 178 |
| LLPS-Dac-2082 | Daucus carota | 80.37 | 5e-56 | 177 |
| LLPS-Mae-1833 | Manihot esculenta | 80.0 | 7e-57 | 180 |
| LLPS-Thc-1473 | Theobroma cacao | 79.25 | 8e-56 | 178 |
| LLPS-Sot-2290 | Solanum tuberosum | 78.3 | 1e-54 | 175 |
| LLPS-Nia-0471 | Nicotiana attenuata | 78.18 | 2e-58 | 183 |
| LLPS-Zem-1892 | Zea mays | 77.45 | 1e-51 | 167 |
| LLPS-Hea-2160 | Helianthus annuus | 76.7 | 8e-53 | 170 |
| LLPS-Viv-2266 | Vitis vinifera | 76.58 | 7e-55 | 175 |
| LLPS-Sol-1368 | Solanum lycopersicum | 76.07 | 2e-59 | 186 |
| LLPS-Sei-1537 | Setaria italica | 75.73 | 8e-52 | 168 |
| LLPS-Orm-1037 | Oryza meridionalis | 75.25 | 5e-50 | 163 |
| LLPS-Cus-2222 | Cucumis sativus | 74.76 | 5e-50 | 162 |
| LLPS-Hov-2115 | Hordeum vulgare | 72.9 | 2e-52 | 170 |
| LLPS-Org-2217 | Oryza glaberrima | 72.73 | 2e-52 | 170 |
| LLPS-Ori-2463 | Oryza indica | 71.82 | 3e-51 | 167 |
| LLPS-Tra-2422 | Triticum aestivum | 71.67 | 3e-53 | 172 |
| LLPS-Phv-1937 | Phaseolus vulgaris | 70.77 | 3e-58 | 183 |
| LLPS-Met-0646 | Medicago truncatula | 70.73 | 1e-57 | 182 |
| LLPS-Amt-0410 | Amborella trichopoda | 69.92 | 1e-54 | 174 |
| LLPS-Tru-0046 | Triticum urartu | 69.05 | 4e-53 | 171 |
| LLPS-Sem-1928 | Selaginella moellendorffii | 68.1 | 2e-51 | 166 |
| LLPS-Php-0879 | Physcomitrella patens | 67.23 | 1e-46 | 155 |
| LLPS-Mua-0332 | Musa acuminata | 67.19 | 8e-54 | 172 |
| LLPS-Sob-2046 | Sorghum bicolor | 66.14 | 1e-52 | 170 |
| LLPS-Orp-0613 | Oryza punctata | 64.34 | 4e-51 | 166 |
| LLPS-Orbr-1710 | Oryza brachyantha | 64.12 | 3e-50 | 164 |
| LLPS-Brd-1271 | Brachypodium distachyon | 63.16 | 9e-52 | 168 |
| LLPS-Lep-2168 | Leersia perrieri | 62.88 | 4e-51 | 167 |
| LLPS-Prp-1511 | Prunus persica | 61.98 | 6e-46 | 152 |
| LLPS-Orl-3904 | Oryzias latipes | 61.7 | 3e-37 | 130 |
| LLPS-Ors-1032 | Oryza sativa | 61.36 | 6e-50 | 163 |
| LLPS-Orr-2095 | Oryza rufipogon | 61.36 | 6e-50 | 163 |
| LLPS-Orb-2207 | Oryza barthii | 61.36 | 6e-50 | 163 |
| LLPS-Orni-2019 | Oryza nivara | 61.36 | 6e-50 | 163 |
| LLPS-Orgl-2276 | Oryza glumaepatula | 61.36 | 6e-50 | 163 |
| LLPS-Gaa-3835 | Gasterosteus aculeatus | 60.64 | 4e-36 | 126 |
| LLPS-Xet-0903 | Xenopus tropicalis | 59.78 | 1e-33 | 121 |
| LLPS-Lac-3619 | Latimeria chalumnae | 59.62 | 7e-39 | 134 |
| LLPS-Xim-0903 | Xiphophorus maculatus | 59.62 | 1e-39 | 136 |
| LLPS-Anc-1124 | Anolis carolinensis | 59.14 | 5e-32 | 117 |
| LLPS-Orn-3739 | Oreochromis niloticus | 59.0 | 2e-38 | 132 |
| LLPS-Pof-0132 | Poecilia formosa | 58.65 | 1e-38 | 134 |
| LLPS-Icp-2981 | Ictalurus punctatus | 58.65 | 9e-39 | 134 |
| LLPS-Scm-0460 | Scophthalmus maximus | 58.0 | 5e-37 | 130 |
| LLPS-Tar-2338 | Takifugu rubripes | 58.0 | 6e-37 | 129 |
| LLPS-Dar-3355 | Danio rerio | 57.69 | 5e-39 | 135 |
| LLPS-Ten-3777 | Tetraodon nigroviridis | 57.0 | 1e-35 | 125 |
| LLPS-Leo-1791 | Lepisosteus oculatus | 56.73 | 2e-36 | 128 |
| LLPS-Gog-4524 | Gorilla gorilla | 56.52 | 9e-30 | 111 |
| LLPS-Mup-1583 | Mustela putorius furo | 56.52 | 2e-29 | 110 |
| LLPS-Man-0118 | Macaca nemestrina | 55.43 | 4e-29 | 110 |
| LLPS-Pap-4468 | Pan paniscus | 55.43 | 5e-29 | 109 |
| LLPS-Urm-3508 | Ursus maritimus | 55.43 | 5e-29 | 109 |
| LLPS-Pat-0490 | Pan troglodytes | 55.43 | 5e-29 | 109 |
| LLPS-Hos-1655 | Homo sapiens | 55.43 | 5e-29 | 109 |
| LLPS-Rhb-3840 | Rhinopithecus bieti | 55.43 | 4e-29 | 109 |
| LLPS-Mam-2686 | Macaca mulatta | 55.43 | 4e-29 | 110 |
| LLPS-Caf-2524 | Canis familiaris | 55.43 | 6e-29 | 109 |
| LLPS-Poa-4518 | Pongo abelii | 55.43 | 4e-29 | 110 |
| LLPS-Nol-0077 | Nomascus leucogenys | 55.43 | 5e-29 | 109 |
| LLPS-Aon-1661 | Aotus nancymaae | 55.43 | 7e-30 | 112 |
| LLPS-Chs-4652 | Chlorocebus sabaeus | 55.43 | 4e-29 | 110 |
| LLPS-Maf-1548 | Macaca fascicularis | 55.43 | 4e-29 | 110 |
| LLPS-Caj-1249 | Callithrix jacchus | 55.43 | 8e-30 | 112 |
| LLPS-Ova-4296 | Ovis aries | 55.43 | 1e-29 | 111 |
| LLPS-Aim-4354 | Ailuropoda melanoleuca | 55.43 | 4e-29 | 110 |
| LLPS-Mal-4409 | Mandrillus leucophaeus | 55.43 | 3e-29 | 110 |
| LLPS-Paa-0538 | Papio anubis | 55.43 | 4e-29 | 110 |
| LLPS-Cap-2568 | Cavia porcellus | 54.95 | 7e-29 | 109 |
| LLPS-Bot-2239 | Bos taurus | 54.95 | 1e-28 | 108 |
| LLPS-Asm-2849 | Astyanax mexicanus | 54.81 | 6e-36 | 127 |
| LLPS-Fec-1257 | Felis catus | 54.35 | 1e-28 | 108 |
| LLPS-Otg-4631 | Otolemur garnettii | 54.35 | 1e-28 | 108 |
| LLPS-Eqc-2549 | Equus caballus | 54.35 | 3e-27 | 105 |
| LLPS-Sus-4327 | Sus scrofa | 54.35 | 8e-29 | 109 |
| LLPS-Chr-1582 | Chlamydomonas reinhardtii | 54.17 | 3e-33 | 121 |
| LLPS-Ora-2591 | Ornithorhynchus anatinus | 53.85 | 1e-28 | 108 |
| LLPS-Mum-3458 | Mus musculus | 53.85 | 2e-29 | 110 |
| LLPS-Dio-3141 | Dipodomys ordii | 53.85 | 2e-28 | 108 |
| LLPS-Tut-1294 | Tursiops truncatus | 53.85 | 2e-28 | 107 |
| LLPS-Ran-3813 | Rattus norvegicus | 53.85 | 1e-29 | 111 |
| LLPS-Gas-0636 | Galdieria sulphuraria | 53.06 | 1e-29 | 115 |
| LLPS-Loa-2272 | Loxodonta africana | 51.22 | 4e-08 | 51.6 |
| LLPS-Sah-2534 | Sarcophilus harrisii | 50.5 | 1e-28 | 108 |
| LLPS-Ict-2974 | Ictidomys tridecemlineatus | 49.57 | 2e-29 | 110 |
| LLPS-Mod-3373 | Monodelphis domestica | 49.5 | 1e-27 | 106 |
| LLPS-Orc-3944 | Oryctolagus cuniculus | 48.7 | 1e-28 | 108 |
| LLPS-Myl-1010 | Myotis lucifugus | 48.33 | 4e-29 | 110 |
| LLPS-Fus-1446 | Fusarium solani | 38.71 | 3e-13 | 66.6 |