LLPS-Bot-a942
ADCY5
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Adenylate cyclase |
| Gene Name: | ADCY5 |
| Ensembl Gene: | ENSBTAG00000018777.6 |
| Ensembl Protein: | ENSBTAP00000072539.1 |
| Organism: | Bos taurus |
| Taxa ID: | 9913 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Postsynaptic density | Predicted from orthologs | (View) |
▼ FUNCTION
| Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSBTAT00000071654.1 | ENSBTAP00000072539.1 |
| Ensembl | ENSBTAT00000032274.5 | ENSBTAP00000032210.5 |
| UniProt | E1BHU9, E1BHU9_BOVIN | |
| RefSeq | NM_001192069.1 | NP_001178998.1 |
| Entrez | 505740 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MSSSKSVSPP GYAAQTAAAP ASRGGPEHRS AWGEADSRAN GYPQAPGGSA RGSTKRPGGA 60 61 VTPQQQQRLA SRWRSDDEDD PPLSGDDPLA GGFGFSFRSK SAWQERGGDD CGRGSRRQRR 120 121 GAAGGGSTRA PPAGSGGGSA AAAAAAGGTE VRPRSVELGL EERRGKGRAA DDLEAGAVEE 180 181 DEGSGDGGSS AGSGAGPGAV LSLGACCLAL LQIFRSKKFP SDKLERLYQR YFFRLNQSSL 240 241 TMLMAVLVLV CLVMLAFHAA RPPLQLPYLA VLAAAVGVIL VMAVLCNRAA FHQDHMGLAC 300 301 YALIAVVLAV QVVGLLLPQP RSASEGIWWT VFFIYTIYTL LPVRMRAAVL SGVLLSALHL 360 361 AIALRTNAQD QFLLKQLVSN VLIFSCTNIV GVCTHYPAEV SQRQAFQETR ECIQARLHSQ 420 421 RENQQQERLL LSVLPRHVAM EMKADINAKQ EDMMFHKIYI QKHDNVSILF ADIEGFTSLA 480 481 SQCTAQELVM TLNELFARFD KLAAENHCLR IKILGDCYYC VSGLPEARAD HAHCCVEMGM 540 541 DMIEAISLVR EVTGVNVNMR VGIHSGRVHC GVLGLRKWQF DVWSNDVTLA NHMEAGGKAG 600 601 RIHITKATLN YLNGDYEVEP GCGGERNAYL KEHSIETFLI LRCTQKRKEE KAMIAKMNRQ 660 661 RTNSIGHNPP HWGAERPFYN HLGGNQVSKE MKRMGFEDPK DKNAQESSNP EDEVDEFLGR 720 721 AIDARSIDRL RSEHVRKFLL TFREPDLEKK YSKQVDDRFG AYVACASLVF LFICFVQITI 780 781 VPHSVFMLSF YLTCFLLLTL VVFVSVIYSC VKLFPAPLQT LSRKIVRSKM NSTLVGVFTI 840 841 TLVFLSAFVN MFTCNSKDLF GCLGDEHNIS ASQVNACHVV ESAVNYSLGD EQGFCGSSWP 900 901 NCNFPEYFTY SVLLSLLACS VFLQISCIGK LVLMLAIELI YVLVVEVPGV TLFDNADLLV 960 961 TANAIDFNNN GTSQCPEHPT KVALKVVTPI IISVFVLALY LHAQQVESTA RLDFLWKLQA 1020 1021 TEEKEEMEEL QAYNRRLLHN ILPKDVAAHF LARERRNDEL YYQSCECVAV MFASIANFSE 1080 1081 FYVELEANNE GVECLRLLNE IIADFDEIIS EDRFRQLEKI KTIGSTYMAA SGLNDSTYDK 1140 1141 VGKTHIKALA DFAMKLMDQM KYINEHSFNN FQMKIGLNIG PVVAGVIGAR KPQYDIWGNT 1200 1201 VNVASRMDST GVPDRIQVTT DMYQVLAANT YQLECRGVVK VKGKGEMMTY FLNGGPPPS 1259 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGTCCAGCT CCAAAAGCGT GAGCCCCCCG GGCTACGCGG CGCAGACAGC GGCGGCGCCG 60 61 GCGTCCCGGG GAGGCCCGGA ACACCGCTCC GCGTGGGGAG AGGCCGACTC CCGCGCCAAT 120 121 GGCTACCCCC AAGCCCCCGG GGGTTCTGCC CGCGGCTCCA CCAAGAGACC TGGGGGGGCG 180 181 GTGACCCCGC AGCAGCAACA GCGCCTGGCC AGCCGCTGGC GCAGCGACGA CGAAGACGAT 240 241 CCTCCGCTGA GTGGCGATGA CCCCCTGGCC GGGGGCTTCG GCTTCAGCTT CCGTTCCAAG 300 301 TCGGCCTGGC AGGAGCGCGG CGGCGACGAC TGCGGTCGCG GCAGCCGGCG GCAGCGGCGG 360 361 GGCGCGGCCG GCGGGGGCAG CACCCGGGCG CCCCCTGCGG GCAGCGGCGG CGGTTCGGCG 420 421 GCTGCGGCCG CCGCAGCGGG CGGGACGGAA GTGCGCCCCC GTTCGGTGGA GCTAGGCCTG 480 481 GAGGAGCGGC GTGGCAAGGG CCGCGCGGCC GACGATCTGG AGGCCGGCGC CGTCGAGGAA 540 541 GACGAAGGGT CCGGGGATGG GGGCAGCTCG GCAGGCTCGG GCGCGGGGCC TGGCGCGGTG 600 601 CTGTCGCTGG GCGCCTGCTG CCTGGCACTG CTGCAGATAT TCCGCTCTAA GAAGTTCCCA 660 661 TCGGACAAGC TGGAGCGGCT GTACCAGCGC TACTTCTTCC GTCTGAACCA GAGCAGCCTC 720 721 ACAATGCTCA TGGCTGTGCT GGTGCTCGTG TGCCTAGTCA TGTTGGCCTT CCACGCGGCA 780 781 CGGCCCCCGC TGCAGCTGCC CTACCTGGCC GTCCTAGCGG CCGCCGTGGG TGTGATCCTC 840 841 GTTATGGCCG TGCTCTGCAA CCGTGCCGCC TTCCACCAGG ACCACATGGG CCTGGCCTGC 900 901 TACGCGCTTA TCGCCGTGGT GCTGGCCGTC CAGGTGGTGG GCCTGTTGCT GCCCCAGCCG 960 961 CGCAGTGCCT CCGAGGGCAT CTGGTGGACT GTGTTTTTCA TCTATACGAT CTACACGCTC 1020 1021 CTGCCCGTGC GCATGCGGGC TGCGGTACTC AGCGGGGTGC TCCTGTCCGC CCTCCACCTG 1080 1081 GCCATCGCCC TGCGCACCAA CGCCCAGGAT CAGTTCCTGC TCAAGCAGCT CGTCTCCAAC 1140 1141 GTCCTCATTT TCTCCTGCAC CAACATTGTG GGTGTGTGCA CCCACTACCC GGCTGAGGTC 1200 1201 TCGCAGAGGC AGGCCTTCCA GGAGACCCGG GAGTGCATCC AGGCTCGGCT CCACTCACAG 1260 1261 CGGGAGAACC AGCAGCAGGA GCGGCTCCTG CTGTCTGTCC TTCCCCGTCA CGTTGCCATG 1320 1321 GAGATGAAAG CCGACATCAA CGCCAAACAG GAGGATATGA TGTTCCATAA GATTTACATC 1380 1381 CAGAAACATG ACAACGTGAG CATTCTGTTT GCTGACATCG AGGGTTTCAC CAGCCTGGCA 1440 1441 TCCCAGTGCA CTGCCCAGGA GCTGGTCATG ACCCTCAACG AGCTCTTCGC CCGCTTCGAC 1500 1501 AAGCTGGCTG CGGAGAATCA CTGTTTACGT ATTAAGATCC TGGGAGATTG TTATTACTGT 1560 1561 GTCTCAGGGC TGCCTGAAGC CAGGGCTGAC CACGCCCACT GCTGCGTGGA GATGGGCATG 1620 1621 GACATGATCG AGGCCATCTC GCTGGTCCGG GAGGTGACAG GTGTGAACGT GAACATGCGT 1680 1681 GTGGGAATTC ACAGCGGGAG AGTGCACTGC GGTGTCCTCG GCCTCAGGAA GTGGCAGTTC 1740 1741 GATGTCTGGT CTAACGATGT CACACTGGCC AACCACATGG AGGCTGGAGG CAAGGCGGGA 1800 1801 CGCATCCACA TCACCAAGGC CACTCTCAAC TACTTGAATG GTGACTACGA AGTGGAGCCA 1860 1861 GGCTGTGGGG GCGAGCGCAA CGCCTACCTC AAGGAGCACA GTATCGAGAC CTTTCTCATC 1920 1921 CTGCGCTGCA CCCAGAAGCG GAAAGAAGAG AAGGCCATGA TTGCCAAGAT GAACCGTCAG 1980 1981 AGAACCAACT CCATCGGGCA CAACCCGCCC CACTGGGGGG CCGAGCGCCC CTTCTATAAC 2040 2041 CACCTGGGGG GCAACCAGGT GTCCAAGGAG ATGAAGCGGA TGGGCTTTGA AGACCCCAAG 2100 2101 GACAAGAATG CCCAGGAAAG TTCGAACCCT GAGGATGAAG TGGATGAATT TCTGGGCCGT 2160 2161 GCCATTGATG CCAGGAGCAT CGACAGGCTG CGATCTGAAC ATGTTCGCAA GTTCCTCTTG 2220 2221 ACCTTCAGGG AGCCTGACTT AGAGAAGAAG TACTCCAAGC AGGTGGATGA CCGATTCGGT 2280 2281 GCCTACGTGG CCTGTGCCTC GCTCGTCTTC CTCTTCATCT GCTTTGTCCA GATCACCATT 2340 2341 GTGCCCCACT CCGTGTTCAT GTTGAGTTTC TACCTGACCT GTTTCCTGCT GCTGACCTTG 2400 2401 GTGGTGTTTG TGTCCGTGAT CTATTCTTGC GTGAAGCTCT TCCCAGCCCC GCTGCAGACG 2460 2461 CTCTCCAGGA AGATCGTGCG GTCCAAGATG AACAGCACCC TGGTGGGGGT GTTCACCATC 2520 2521 ACCCTCGTGT TCCTGTCGGC TTTCGTCAAC ATGTTCACGT GCAACTCCAA GGACCTGTTT 2580 2581 GGCTGCCTGG GGGACGAGCA CAACATCAGT GCCAGTCAGG TCAATGCATG CCACGTGGTG 2640 2641 GAGTCGGCCG TCAACTACAG TCTGGGTGAC GAGCAGGGCT TCTGCGGCAG CTCCTGGCCC 2700 2701 AACTGCAACT TCCCCGAGTA CTTCACCTAT AGCGTGCTGC TCAGCCTGCT GGCCTGCTCC 2760 2761 GTGTTCCTGC AGATCAGCTG CATCGGGAAG CTGGTGCTCA TGCTGGCCAT CGAGCTCATC 2820 2821 TACGTGCTCG TCGTTGAGGT GCCCGGTGTC ACGCTCTTTG ACAATGCCGA CCTACTGGTC 2880 2881 ACGGCCAACG CCATAGACTT CAACAACAAC GGGACCTCCC AGTGCCCTGA GCATCCAACC 2940 2941 AAGGTGGCGC TGAAGGTGGT GACGCCCATC ATCATCTCCG TCTTCGTGCT GGCCCTGTAC 3000 3001 CTGCATGCCC AGCAGGTGGA GTCCACTGCC CGCCTCGACT TCCTCTGGAA ACTTCAGGCC 3060 3061 ACGGAGGAGA AGGAGGAGAT GGAGGAGCTG CAGGCCTACA ACCGGCGGCT GCTGCACAAC 3120 3121 ATTCTGCCCA AGGACGTGGC CGCACACTTC CTGGCCCGCG AACGGCGCAA CGACGAGCTC 3180 3181 TACTATCAGT CGTGCGAGTG CGTGGCCGTC ATGTTCGCCT CCATCGCCAA CTTCTCTGAG 3240 3241 TTCTACGTGG AACTAGAGGC CAACAACGAG GGCGTCGAGT GCCTGCGGCT GCTCAACGAG 3300 3301 ATCATCGCAG ACTTTGACGA GATCATTAGT GAGGACCGGT TCAGGCAGCT GGAAAAGATC 3360 3361 AAGACCATCG GCAGCACCTA CATGGCCGCC TCCGGCCTCA ATGACTCCAC CTACGACAAG 3420 3421 GTGGGCAAGA CCCACATCAA AGCCCTGGCC GACTTCGCCA TGAAGTTGAT GGACCAAATG 3480 3481 AAGTACATCA ACGAGCACTC TTTCAACAAC TTCCAGATGA AGATCGTCCT CAAAACTCTT 3540 3541 CCCTCCACCA ACTTCCTCTT TGGGTCCATC AAGCCACAGG AAGACATCCC TGCGTCTGTA 3600 3601 GGAAAAAGTA ACTCTTATTC TGAAAGCCTG GGTATCCTTG ACAAGATAAG AGTCACCACA 3660 3661 GACATGTACC AGGTGCTGGC CGCCAATACG TACCAGCTGG AGTGCCGGGG TGTGGTCAAG 3720 3721 GTCAAGGGCA AAGGCGAGAT GATGACCTAC TTCCTCAACG GAGGACCCCC GCCCAGTTAG 3780 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Cilium | |
Cellular Component | Integral component of plasma membrane | |
Cellular Component | Intermediate filament cytoskeleton | |
Molecular Function | Adenylate cyclase activity | |
Molecular Function | Adenylate cyclase binding | |
Molecular Function | ATP binding | |
Molecular Function | Metal ion binding | |
Molecular Function | Protein heterodimerization activity | |
Molecular Function | Scaffold protein binding | |
Biological Process | Adenosine receptor signaling pathway | |
Biological Process | Adenylate cyclase-activating dopamine receptor signaling pathway | |
Biological Process | Adenylate cyclase-activating G protein-coupled receptor signaling pathway | |
Biological Process | Adenylate cyclase-inhibiting dopamine receptor signaling pathway | |
Biological Process | CAMP biosynthetic process | |
Biological Process | Cellular response to forskolin | |
Biological Process | Locomotory behavior | |
Biological Process | Neuromuscular process controlling balance | |
Biological Process | Positive regulation of cytosolic calcium ion concentration | |
Biological Process | Regulation of insulin secretion involved in cellular response to glucose stimulus |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Hos-a957 | Homo sapiens | 0.0 | 2556 | undefined |
| LLPS-Mum-a942 | Mus musculus | 0.0 | 2339 | undefined |