LLPS-Bot-4794
AKAP1
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | A-kinase anchoring protein 1 |
| Gene Name: | AKAP1 |
| Ensembl Gene: | ENSBTAG00000025320.5 |
| Ensembl Protein: | ENSBTAP00000046086.3 |
| Organism: | Bos taurus |
| Taxa ID: | 9913 |
| LLPS Type: | Client |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Postsynaptic density | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSBTAT00000049153.4 | ENSBTAP00000046086.3 |
| UniProt | E1BMU6, E1BMU6_BOVIN | |
| RefSeq | XM_005195570.3, XM_005219948.3, XM_010815724.2, XM_010823966.2, XM_015458519.1, XM_015467923.1 | XP_005195627.1, XP_005220005.1, XP_010814026.1, XP_010822268.1, XP_015314005.1, XP_015323409.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MTIQFRSLFP LALPGVLALL GWWWFFSRKK EPLDSHDRAA EAGAVALRAG PEAQEVLPVE 60 61 DSRPGAASPP PERELCGGGR PSPEPAALLR AHPACRRSES SGSLPNPADT RLRPGARKEV 120 121 ELTLAGDEAK AVPLECPLPA PKGLPFPHEA VEVCKREAVL GRPGGRGRQG QPAAPAEKPA 180 181 PEEKARETGG AEGTGDAVLG ENVLEEGPAA WEPAPELELQ SSRAAGAGEK DPGRLLEEAV 240 241 VEAAPEEETL APRGLAGRAW DGAFPQEQGG EETWDRSEKI EQAAFQIISK VILEATEEVL 300 301 ATTMGRIAGR VYQASATQPQ GLKEESCAPA SQKTPLGLEA SEPTLTAVEA APGLRDTALP 360 361 STEPPAGDLP APKTYVSCLS SPLSSPTKDR KPKNSAHHIS LAPCPLPAAP LRELLDEAGG 420 421 TGEETTHVPC VSDGGQAVPC GAASGQCSDS ASTSGLEDCC LETSPSPRGE AATPPLPEST 480 481 VPVSNGVLKG ELSDLGTEDG WTVDAEADHS GGSDGNSMDS VDSCCGFRKP DDFQNAQAGS 540 541 NPKKVDLIIW EIEVPKHLVG RLIGKQGRYV SFLKQTSGAK IYISTLPYTQ NIQVCHIEGS 600 601 QHHVDKALNL IGKKFKELNL TNIYAPPLPS LALPSLPMTS WLMLPDGVTV EVIVVNQVNA 660 661 GHLFVQQHTH PTFHALRSLD QQMYLCYSQP GIPTLPTPVE ITVICAAPGV DGAWWRAQVV 720 721 AAYEDTNEVE IRYVDYGGYK RVKVDVLRQI RSDFVTLPFQ GAEVLLDSVM PLSDDDHFSP 780 781 EADAAMSEMT GNTALLAQVT SYSPTGLPLI QLWSVVGDEV VLINRSLVER GLAQWVDSCY 840 841 SSL 843 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGACGATCC AGTTCCGTTC ACTCTTCCCC CTGGCCCTGC CTGGAGTGCT GGCGCTCCTC 60 61 GGCTGGTGGT GGTTTTTCTC CCGTAAAAAA GAGCCCCTCG ACAGCCACGA CAGAGCAGCG 120 121 GAGGCCGGTG CGGTGGCGCT GCGGGCCGGC CCTGAGGCCC AGGAGGTGCT CCCAGTGGAA 180 181 GATTCGCGGC CTGGAGCAGC CAGCCCACCG CCTGAGAGGG AGCTGTGCGG TGGTGGCAGG 240 241 CCCTCGCCGG AGCCGGCGGC CCTGTTGCGG GCACACCCGG CCTGCCGGAG GTCCGAGTCC 300 301 TCGGGCAGCC TTCCGAACCC CGCGGACACG AGACTCCGCC CGGGAGCGCG CAAGGAGGTG 360 361 GAGCTCACCC TCGCGGGCGA CGAAGCCAAG GCTGTCCCTC TAGAGTGTCC CCTGCCAGCC 420 421 CCCAAGGGCC TTCCGTTCCC CCACGAGGCA GTCGAGGTGT GTAAGCGAGA GGCCGTGCTG 480 481 GGACGGCCGG GGGGACGGGG CCGCCAGGGT CAGCCTGCAG CCCCCGCGGA AAAGCCGGCC 540 541 CCTGAAGAGA AGGCCCGGGA GACAGGGGGC GCCGAAGGCA CGGGGGACGC GGTGCTGGGA 600 601 GAGAATGTGC TGGAGGAAGG GCCGGCGGCC TGGGAGCCAG CCCCCGAGTT AGAGTTACAG 660 661 AGCAGCCGGG CGGCCGGAGC GGGAGAGAAG GACCCGGGCC GCCTGCTGGA GGAGGCCGTG 720 721 GTGGAGGCGG CACCCGAGGA GGAGACGCTG GCGCCGCGGG GCCTGGCGGG CCGAGCCTGG 780 781 GATGGAGCCT TTCCCCAGGA GCAGGGTGGG GAGGAGACTT GGGACAGAAG CGAGAAGATC 840 841 GAGCAGGCTG CCTTCCAGAT CATCTCCAAA GTGATCCTGG AGGCCACCGA GGAGGTGCTG 900 901 GCCACCACCA TGGGCAGGAT TGCAGGCCGG GTGTATCAGG CCTCAGCCAC CCAGCCCCAA 960 961 GGGCTGAAGG AGGAGAGCTG TGCCCCCGCC AGCCAGAAAA CCCCCCTGGG CCTGGAGGCC 1020 1021 TCGGAGCCTA CCCTGACTGC GGTAGAGGCG GCCCCGGGTC TGAGGGACAC GGCCCTCCCC 1080 1081 TCCACAGAGC CTCCGGCAGG GGACCTGCCA GCGCCAAAGA CCTACGTGAG CTGCCTGAGC 1140 1141 AGCCCTCTGT CCAGCCCCAC CAAGGACAGG AAGCCAAAGA ACTCTGCACA CCACATCTCC 1200 1201 CTGGCCCCCT GCCCTCTGCC GGCTGCCCCC CTCCGCGAGT TGCTGGACGA GGCAGGCGGC 1260 1261 ACCGGGGAAG AGACCACCCA TGTCCCCTGC GTGTCTGACG GCGGCCAGGC TGTCCCCTGT 1320 1321 GGCGCGGCCT CTGGGCAGTG CTCAGATTCC GCCAGCACCT CGGGGCTTGA AGACTGTTGT 1380 1381 CTGGAGACCT CCCCCAGCCC CAGGGGCGAG GCCGCCACCC CACCGCTGCC CGAAAGTACT 1440 1441 GTGCCCGTCA GCAATGGGGT GCTGAAGGGG GAGCTGTCAG ACTTGGGGAC TGAGGACGGA 1500 1501 TGGACCGTGG ACGCGGAAGC AGACCATTCG GGAGGCTCAG ACGGGAACAG CATGGACTCG 1560 1561 GTGGACAGCT GCTGTGGCTT CAGGAAGCCT GACGATTTCC AGAATGCCCA GGCAGGCTCC 1620 1621 AATCCCAAGA AGGTCGACCT GATCATCTGG GAGATCGAGG TGCCAAAGCA CCTGGTTGGT 1680 1681 CGGTTGATTG GCAAGCAGGG ACGCTACGTG AGTTTTCTCA AGCAGACATC TGGTGCCAAG 1740 1741 ATCTACATCT CCACCCTGCC TTACACCCAG AACATCCAGG TCTGCCACAT CGAAGGCTCT 1800 1801 CAGCATCATG TGGACAAGGC GCTGAACTTG ATTGGCAAGA AGTTCAAAGA ACTGAACCTC 1860 1861 ACCAACATTT ACGCTCCCCC GCTGCCTTCG CTGGCACTGC CTTCTCTTCC AATGACTTCC 1920 1921 TGGCTCATGC TTCCGGACGG TGTCACTGTG GAGGTAATCG TGGTCAACCA GGTCAACGCC 1980 1981 GGGCACCTGT TTGTGCAGCA GCACACACAC CCCACCTTCC ACGCGCTGCG CAGCCTGGAC 2040 2041 CAGCAGATGT ACCTCTGCTA CTCTCAGCCT GGCATCCCCA CCTTGCCCAC CCCAGTGGAG 2100 2101 ATAACAGTCA TCTGCGCTGC TCCTGGCGTG GACGGGGCCT GGTGGCGAGC CCAGGTGGTG 2160 2161 GCCGCCTACG AGGACACCAA CGAGGTCGAG ATTCGCTACG TCGACTATGG TGGCTACAAG 2220 2221 AGGGTGAAGG TAGACGTGCT GCGGCAGATC CGGTCTGACT TTGTGACCCT GCCGTTCCAG 2280 2281 GGAGCGGAGG TGCTTCTGGA CAGCGTGATG CCCCTGTCAG ACGATGACCA CTTCTCCCCC 2340 2341 GAGGCGGACG CGGCTATGAG CGAGATGACG GGGAACACAG CGCTGCTGGC TCAGGTTACG 2400 2401 AGTTACAGCC CAACCGGCCT TCCTCTGATT CAACTGTGGA GCGTGGTTGG AGATGAAGTG 2460 2461 GTGTTGATAA ACCGGTCGCT GGTGGAGCGA GGACTCGCTC AGTGGGTGGA CAGCTGCTAC 2520 2521 TCGAGCCTCT GA 2532 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Ova-3502 | Ovis aries | 94.77 | 0.0 | 1018 |
| LLPS-Eqc-2003 | Equus caballus | 85.03 | 0.0 | 911 |
| LLPS-Mod-4182 | Monodelphis domestica | 84.66 | 0.0 | 536 |
| LLPS-Otg-1716 | Otolemur garnettii | 83.13 | 0.0 | 846 |
| LLPS-Paa-2259 | Papio anubis | 81.82 | 0.0 | 847 |
| LLPS-Maf-2889 | Macaca fascicularis | 81.82 | 0.0 | 847 |
| LLPS-Cea-1853 | Cercocebus atys | 81.82 | 0.0 | 847 |
| LLPS-Man-3092 | Macaca nemestrina | 81.82 | 0.0 | 847 |
| LLPS-Mam-3229 | Macaca mulatta | 81.54 | 0.0 | 821 |
| LLPS-Cap-4674 | Cavia porcellus | 81.32 | 0.0 | 834 |
| LLPS-Mum-2039 | Mus musculus | 80.28 | 0.0 | 825 |
| LLPS-Dio-0989 | Dipodomys ordii | 78.72 | 0.0 | 812 |
| LLPS-Ran-0953 | Rattus norvegicus | 78.56 | 0.0 | 830 |
| LLPS-Sus-2067 | Sus scrofa | 76.46 | 0.0 | 1081 |
| LLPS-Anc-2528 | Anolis carolinensis | 75.76 | 5e-144 | 435 |
| LLPS-Lac-3739 | Latimeria chalumnae | 75.52 | 4e-165 | 509 |
| LLPS-Mea-2686 | Mesocricetus auratus | 73.99 | 0.0 | 720 |
| LLPS-Aim-4360 | Ailuropoda melanoleuca | 73.46 | 0.0 | 989 |
| LLPS-Fec-3704 | Felis catus | 72.73 | 0.0 | 982 |
| LLPS-Icp-2161 | Ictalurus punctatus | 72.49 | 5e-153 | 478 |
| LLPS-Tar-0689 | Takifugu rubripes | 72.11 | 3e-146 | 456 |
| LLPS-Ict-3025 | Ictidomys tridecemlineatus | 71.6 | 0.0 | 603 |
| LLPS-Caj-3144 | Callithrix jacchus | 71.53 | 0.0 | 1009 |
| LLPS-Scf-2155 | Scleropages formosus | 71.35 | 2e-154 | 482 |
| LLPS-Ten-0470 | Tetraodon nigroviridis | 71.26 | 7e-151 | 467 |
| LLPS-Mup-2622 | Mustela putorius furo | 71.1 | 0.0 | 979 |
| LLPS-Asm-2038 | Astyanax mexicanus | 70.98 | 7e-153 | 477 |
| LLPS-Myl-1828 | Myotis lucifugus | 70.86 | 0.0 | 1009 |
| LLPS-Caf-1962 | Canis familiaris | 70.79 | 0.0 | 1002 |
| LLPS-Scm-2775 | Scophthalmus maximus | 70.45 | 5e-149 | 466 |
| LLPS-Orn-3916 | Oreochromis niloticus | 69.41 | 5e-150 | 466 |
| LLPS-Poa-3257 | Pongo abelii | 69.22 | 0.0 | 998 |
| LLPS-Nol-1411 | Nomascus leucogenys | 68.87 | 0.0 | 991 |
| LLPS-Mal-1744 | Mandrillus leucophaeus | 68.71 | 0.0 | 983 |
| LLPS-Rhb-2780 | Rhinopithecus bieti | 68.25 | 0.0 | 977 |
| LLPS-Chs-4305 | Chlorocebus sabaeus | 68.07 | 0.0 | 973 |
| LLPS-Aon-4210 | Aotus nancymaae | 68.07 | 0.0 | 965 |
| LLPS-Fud-4100 | Fukomys damarensis | 68.06 | 0.0 | 922 |
| LLPS-Gog-0701 | Gorilla gorilla | 67.92 | 0.0 | 984 |
| LLPS-Pap-2865 | Pan paniscus | 67.73 | 0.0 | 976 |
| LLPS-Orc-2550 | Oryctolagus cuniculus | 67.71 | 0.0 | 940 |
| LLPS-Pat-0734 | Pan troglodytes | 67.62 | 0.0 | 974 |
| LLPS-Hos-4688 | Homo sapiens | 67.59 | 0.0 | 983 |
| LLPS-Pof-4177 | Poecilia formosa | 67.42 | 5e-144 | 453 |
| LLPS-Leo-3859 | Lepisosteus oculatus | 67.34 | 5e-163 | 503 |
| LLPS-Loa-4493 | Loxodonta africana | 67.31 | 0.0 | 949 |
| LLPS-Sah-1259 | Sarcophilus harrisii | 67.06 | 0.0 | 676 |
| LLPS-Xim-2860 | Xiphophorus maculatus | 66.01 | 8e-141 | 444 |
| LLPS-Ora-0638 | Ornithorhynchus anatinus | 64.47 | 0.0 | 639 |
| LLPS-Orl-2421 | Oryzias latipes | 63.95 | 1e-71 | 241 |
| LLPS-Cas-1909 | Carlito syrichta | 63.79 | 9e-62 | 224 |
| LLPS-Tag-2021 | Taeniopygia guttata | 62.62 | 2e-158 | 477 |
| LLPS-Gaga-2575 | Gallus gallus | 61.21 | 0.0 | 621 |
| LLPS-Meg-2044 | Meleagris gallopavo | 60.69 | 0.0 | 608 |
| LLPS-Pes-2968 | Pelodiscus sinensis | 60.38 | 0.0 | 607 |
| LLPS-Anp-2945 | Anas platyrhynchos | 60.21 | 0.0 | 595 |
| LLPS-Dar-0763 | Danio rerio | 58.22 | 4e-99 | 327 |
| LLPS-Urm-2434 | Ursus maritimus | 56.3 | 7e-109 | 351 |
| LLPS-Fia-3710 | Ficedula albicollis | 51.89 | 8e-162 | 501 |
| LLPS-Gaa-1760 | Gasterosteus aculeatus | 51.13 | 2e-88 | 303 |
| LLPS-Cii-1527 | Ciona intestinalis | 38.38 | 1e-40 | 154 |
| LLPS-Drm-0318 | Drosophila melanogaster | 30.64 | 2e-39 | 159 |
| LLPS-Tut-2105 | Tursiops truncatus | 29.27 | 4e-08 | 61.6 |
| LLPS-Mel-0838 | Melampsora laricipopulina | 28.89 | 2e-06 | 55.8 |