• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Bot-4660
HSPA6

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Heat shock protein family A (Hsp70) member 6
Gene Name: HSPA6
Ensembl Gene: ENSBTAG00000039035.3
Ensembl Protein: ENSBTAP00000051168.3
Organism: Bos taurus
Taxa ID: 9913
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nuclear speckle, Nucleolus, Postsynaptic densityPredicted from orthologs(View)

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MELAIGIDLG  TTYSCVGVFQ  HGRVEILAND  QGNRTTPSYV  AFSDTERLVG  DAAKSQAALN  60
61    PHNTVFDVKR  LIGRRFTDPS  VQSDMKHWPF  QVVSEGGKPK  VRVSYRGEDK  AFYPEEISSM  120
121   VLSKMKETAE  AYLGQPVKHA  VITVPAYFND  SQRQATKDAG  AIAGLNVLRI  INEPTAAAIA  180
181   YGLDRLGAGE  RNVLIFDLGG  GTFDVSVLTI  DAGVFEVKAT  AGDTHLGGED  FDNRLVNHFM  240
241   EEFRRKHGKD  LSRNKRALRR  LRTACERAKR  TLSSSTQATL  EIDSLFEGVD  FYTSITRARF  300
301   EELCSDLFRS  TLEPVEKALR  DAKLGKAQIH  DIVLVGGSTR  IPKVQKLLQD  FFDGRELNKS  360
361   INPDEAVAYG  AAVQAAVLMG  DTCEKVQDLL  LLDVAPLSLG  LETAGGVMTT  LIQRNATIPT  420
421   KQTQTFTTYS  DNQPGVLIQV  YEGERAMTRD  NNLLGRFELS  GIPPAPRGVP  QIEVTFDIDA  480
481   NGILSVTATD  RSTGKANKIT  ITNDKGRLSK  EEVERMVREA  EQYKAEDEAQ  RDRVAAKNSL  540
541   EAYVFHVKSS  LQEERLRDKI  PEEDRRKVQD  KCQEVLAWLE  HNQLADKEEY  EHQKRELEQI  600
601   CCPIFSRLYG  GPGVSVGSSC  GAQARHGAPS  TGPVIEEVD  639
Nucleotide CDS Sequence (FASTA)
1     ATGGAGCTGG  CCATAGGCAT  CGACCTGGGC  ACCACGTACT  CGTGCGTAGG  CGTGTTTCAG  60
61    CACGGCCGGG  TGGAGATCCT  CGCCAACGAC  CAGGGCAACC  GCACCACCCC  CAGCTACGTG  120
121   GCCTTCTCAG  ACACCGAGCG  GCTGGTGGGC  GACGCGGCCA  AGAGCCAGGC  GGCCCTGAAC  180
181   CCGCACAACA  CCGTGTTCGA  CGTCAAGCGA  CTGATCGGGC  GCAGATTCAC  AGACCCCTCT  240
241   GTGCAGTCGG  ACATGAAGCA  CTGGCCCTTC  CAGGTGGTGA  GCGAGGGCGG  CAAGCCGAAG  300
301   GTGCGCGTGT  CCTACCGCGG  GGAGGACAAG  GCGTTTTACC  CCGAGGAGAT  CTCGTCCATG  360
361   GTGCTGAGCA  AGATGAAGGA  GACGGCGGAG  GCGTACCTGG  GCCAGCCCGT  GAAGCACGCT  420
421   GTAATCACGG  TGCCTGCCTA  CTTCAACGAC  TCGCAGCGTC  AGGCCACTAA  GGACGCGGGT  480
481   GCCATCGCGG  GGCTCAACGT  CCTGAGAATC  ATCAACGAGC  CCACGGCAGC  TGCCATCGCC  540
541   TACGGCCTGG  ACCGGCTGGG  CGCCGGAGAG  CGCAACGTGC  TCATTTTCGA  CCTGGGTGGG  600
601   GGCACCTTCG  ACGTGTCGGT  CCTCACCATC  GACGCTGGTG  TCTTTGAGGT  GAAGGCCACG  660
661   GCTGGAGACA  CTCACCTGGG  TGGAGAGGAC  TTCGACAACC  GGCTGGTGAA  CCACTTCATG  720
721   GAGGAGTTCC  GGCGGAAGCA  TGGCAAGGAT  TTGAGCAGGA  ACAAGCGGGC  CCTGCGCAGG  780
781   CTCCGCACGG  CCTGCGAGCG  CGCCAAGCGC  ACCCTGTCGT  CCAGTACCCA  GGCCACTCTG  840
841   GAGATCGATT  CCCTGTTTGA  GGGTGTAGAC  TTCTACACTT  CCATCACTCG  AGCCCGCTTT  900
901   GAAGAACTGT  GCTCGGACCT  CTTTCGCAGC  ACCCTGGAGC  CGGTAGAGAA  GGCCTTGCGC  960
961   GATGCCAAGC  TGGGCAAGGC  CCAGATCCAT  GACATTGTCC  TGGTGGGTGG  CTCTACCCGA  1020
1021  ATCCCCAAGG  TACAGAAGCT  CCTGCAGGAC  TTCTTCGATG  GCAGGGAGCT  GAACAAAAGC  1080
1081  ATCAACCCGG  ATGAAGCTGT  GGCTTATGGG  GCTGCTGTGC  AGGCAGCCGT  ATTGATGGGG  1140
1141  GACACGTGTG  AGAAGGTGCA  AGATCTTCTG  CTGCTGGATG  TGGCTCCCCT  GTCCCTGGGG  1200
1201  CTGGAGACAG  CTGGTGGGGT  GATGACTACA  CTGATCCAGA  GGAATGCCAC  TATCCCAACC  1260
1261  AAGCAGACCC  AGACTTTCAC  CACCTATTCA  GACAACCAGC  CTGGGGTCCT  GATTCAGGTG  1320
1321  TATGAGGGTG  AGAGGGCCAT  GACCAGGGAC  AACAACCTGC  TAGGGCGCTT  TGAGCTCAGC  1380
1381  GGCATCCCTC  CTGCCCCACG  TGGAGTCCCC  CAGATCGAGG  TGACCTTCGA  CATTGACGCC  1440
1441  AATGGCATCC  TGAGTGTGAC  AGCCACTGAC  AGGAGCACAG  GCAAAGCTAA  CAAGATCACC  1500
1501  ATCACCAATG  ACAAGGGCCG  GCTGAGCAAG  GAGGAGGTGG  AGAGGATGGT  TCGTGAGGCT  1560
1561  GAGCAGTACA  AGGCTGAGGA  TGAGGCCCAG  AGAGACAGGG  TGGCTGCCAA  AAACTCTCTG  1620
1621  GAGGCCTATG  TCTTCCATGT  GAAGAGCTCC  TTGCAAGAGG  AGAGGCTTAG  AGATAAGATT  1680
1681  CCTGAAGAGG  ACAGGCGCAA  AGTACAAGAC  AAGTGTCAGG  AAGTCCTTGC  TTGGCTGGAG  1740
1741  CACAACCAGT  TAGCAGACAA  AGAGGAATAT  GAGCATCAAA  AGAGGGAGCT  GGAGCAGATC  1800
1801  TGTTGCCCCA  TCTTCTCCAG  GCTCTATGGG  GGGCCTGGTG  TCTCTGTGGG  CAGCAGTTGT  1860
1861  GGAGCCCAAG  CCCGACATGG  AGCCCCTAGT  ACTGGCCCTG  TCATCGAGGA  GGTCGATTAA  1920

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Ova-3711Ovis aries98.270.01060
LLPS-Poa-2599Pongo abelii95.140.01148
LLPS-Cas-0772Carlito syrichta95.140.01144
LLPS-Nol-0333Nomascus leucogenys94.980.01139
LLPS-Hos-2883Homo sapiens94.510.01135
LLPS-Caj-0924Callithrix jacchus93.560.01120
LLPS-Pat-4404Pan troglodytes92.630.01113
LLPS-Ict-3661Ictidomys tridecemlineatus92.320.01114
LLPS-Cap-2847Cavia porcellus91.690.01106
LLPS-Orc-3596Oryctolagus cuniculus86.140.01013
LLPS-Caf-0431Canis familiaris86.070.01003
LLPS-Maf-4587Macaca fascicularis86.050.01020
LLPS-Cea-3535Cercocebus atys85.890.0 997
LLPS-Mup-1328Mustela putorius furo85.760.01004
LLPS-Chs-0084Chlorocebus sabaeus85.150.01014
LLPS-Dio-1867Dipodomys ordii84.160.0 994
LLPS-Sah-1328Sarcophilus harrisii84.050.0 996
LLPS-Ora-0394Ornithorhynchus anatinus83.860.01018
LLPS-Rhb-4635Rhinopithecus bieti83.540.0 964
LLPS-Aim-1567Ailuropoda melanoleuca83.490.01028
LLPS-Mod-0478Monodelphis domestica83.490.01031
LLPS-Fec-2423Felis catus83.330.01024
LLPS-Tut-0804Tursiops truncatus83.180.01021
LLPS-Eqc-0176Equus caballus83.180.01022
LLPS-Ran-0042Rattus norvegicus83.020.01017
LLPS-Otg-3422Otolemur garnettii83.020.01021
LLPS-Mum-1293Mus musculus82.860.01016
LLPS-Loa-1802Loxodonta africana82.860.01025
LLPS-Myl-0675Myotis lucifugus82.70.01012
LLPS-Fud-2196Fukomys damarensis81.480.01002
LLPS-Mea-3681Mesocricetus auratus81.250.0 947
LLPS-Paa-2596Papio anubis81.190.0 991
LLPS-Urm-3959Ursus maritimus80.690.01003
LLPS-Mal-1224Mandrillus leucophaeus80.530.01000
LLPS-Mam-1291Macaca mulatta80.530.01000
LLPS-Man-0982Macaca nemestrina80.530.01000
LLPS-Sus-1055Sus scrofa80.50.0 996
LLPS-Gog-2966Gorilla gorilla80.380.0 996
LLPS-Pap-3889Pan paniscus80.380.0 996
LLPS-Anc-1550Anolis carolinensis80.030.0 969
LLPS-Scf-2646Scleropages formosus79.910.01002
LLPS-Aon-2927Aotus nancymaae79.910.0 978
LLPS-Dar-2346Danio rerio79.780.0 998
LLPS-Cae-0408Caenorhabditis elegans79.740.0 966
LLPS-Gaga-1460Gallus gallus79.70.0 966
LLPS-Anp-1068Anas platyrhynchos79.70.0 966
LLPS-Meg-0622Meleagris gallopavo79.70.0 966
LLPS-Xet-0246Xenopus tropicalis79.570.0 961
LLPS-Tag-2870Taeniopygia guttata79.540.0 964
LLPS-Orn-3641Oreochromis niloticus79.540.0 962
LLPS-Fia-1669Ficedula albicollis79.540.0 964
LLPS-Pes-2810Pelodiscus sinensis79.540.0 964
LLPS-Pof-1118Poecilia formosa79.430.0 997
LLPS-Lac-3661Latimeria chalumnae79.370.0 963
LLPS-Xim-1275Xiphophorus maculatus79.280.0 993
LLPS-Asm-2117Astyanax mexicanus79.280.0 993
LLPS-Orl-2086Oryzias latipes79.210.0 959
LLPS-Icp-0040Ictalurus punctatus79.210.0 961
LLPS-Drm-0680Drosophila melanogaster79.040.0 946
LLPS-Scm-1342Scophthalmus maximus79.040.0 956
LLPS-Gaa-3348Gasterosteus aculeatus78.930.0 978
LLPS-Leo-3312Lepisosteus oculatus78.680.0 984
LLPS-Ten-2048Tetraodon nigroviridis78.550.0 952
LLPS-Tar-1049Takifugu rubripes78.340.0 970
LLPS-Cis-0845Ciona savignyi77.890.0 934
LLPS-Cii-0165Ciona intestinalis77.140.0 907
LLPS-Sob-0277Sorghum bicolor74.550.0 891
LLPS-Asfu-0029Aspergillus fumigatus74.30.0 884
LLPS-Hea-1537Helianthus annuus74.220.0 891
LLPS-Nef-1008Neosartorya fischeri74.140.0 882
LLPS-Zem-1009Zea mays73.730.0 884
LLPS-Aso-0087Aspergillus oryzae73.640.0 881
LLPS-Asf-0953Aspergillus flavus73.640.0 881
LLPS-Lep-1122Leersia perrieri73.560.0 881
LLPS-Orni-0619Oryza nivara73.560.0 880
LLPS-Orr-1512Oryza rufipogon73.560.0 880
LLPS-Orp-0177Oryza punctata73.560.0 881
LLPS-Ors-2372Oryza sativa73.560.0 880
LLPS-Mae-0497Manihot esculenta73.560.0 881
LLPS-Scj-1500Schizosaccharomyces japonicus72.910.0 887
LLPS-Sei-0872Setaria italica72.390.0 889
LLPS-Nia-0436Nicotiana attenuata72.030.0 885
LLPS-Sot-0561Solanum tuberosum71.880.0 882
LLPS-Sol-0780Solanum lycopersicum71.880.0 882
LLPS-Brd-0812Brachypodium distachyon71.810.0 882
LLPS-Orb-1111Oryza barthii71.670.0 887
LLPS-Org-0587Oryza glaberrima71.670.0 887
LLPS-Tra-0234Triticum aestivum71.610.0 881
LLPS-Tru-0074Triticum urartu71.610.0 881
LLPS-Brn-0135Brassica napus71.520.0 885
LLPS-Cus-0398Cucumis sativus71.410.0 882
LLPS-Brr-1523Brassica rapa71.180.0 882
LLPS-Thc-1965Theobroma cacao71.030.0 883
LLPS-Hov-0379Hordeum vulgare70.920.0 882