LLPS-Bot-4323
DDX58
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | DExD/H-box helicase 58 |
| Gene Name: | DDX58 |
| Ensembl Gene: | ENSBTAG00000003366.7 |
| Ensembl Protein: | ENSBTAP00000053514.3 |
| Organism: | Bos taurus |
| Taxa ID: | 9913 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Stress granule | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSBTAT00000061377.3 | ENSBTAP00000053514.3 |
| UniProt | F1MKU1, F1MKU1_BOVIN |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MAQVDQGAWG CPAPSFSFDF PSAARLPLQL RLRAGRSPRQ ISRASRLYLG RAEPSSAEPS 60 61 RAQAKQGVAG SGAAGMTAEQ RRNLHAFRDY VRKILDPTYI LSYMTPWFRD DVVQHIQAKK 120 121 NNKGPMEAAS LFLQVLLELQ EEGWFRGFLD ALQQAGYSGL YEAIESWDFQ KLEKLEEYRL 180 181 LLKRLQPEFK TTINPEDILP EISGCLLNQE CEEIIQISSN KGLMAGAEKM VECLLRSDKE 240 241 NWPKTLKLAL EKEESKFSEL WMVEKGAENV QMKDLEDDEM KTLDVHIVYK EEPESQNLSQ 300 301 NSCSSEVPPT YSPLKPRNYQ LELALPAQKG KNTIICAPTG CGKTFVSLLI CEHHLKKFPQ 360 361 GRKGKVVVFA VQVPLYEQQK SVFSEYFERF GYKVSGISGE TADNISVEQI VENNDIIILT 420 421 PQILVNSLKD GTIPSLSIFT LMIFDECHNT NKHHPYNMIM FHYLDQKLGG SSDSLPQVIG 480 481 LTASVGVGDA KNTAEATEYI CKLCASLDTA VVTTVRDNLE ELEEVVYKPQ KFFRKVESRT 540 541 TDRFKRIISQ LMAETEALAK SIFEELGTVT LENLSRIQNR NFGTQKYEQW IIAVQKACMV 600 601 FQMPDKEEES RICKALFLYT SHLRKYNDAL IINEDARMKD ALNYLKNFFK NVRAAGFDAI 660 661 EQDLTQRFEE KLLELEGISM DPSNENAKLK DLCFILQEEY HLNPETRTIL FVKTRALVDA 720 721 LKNWIEENPK LSFLKPGILT GRGRTNQTMG MTLPAQKCAL DAFRTNRDSK ILIATSVADE 780 781 GIDIAQCNLV ILYEYVGNVI KMIQTRGRGR ARGSKCFLLT SNADVIEKEK LNICQEKMMN 840 841 ESISRLQGWN EAVFKEKIRQ IQIQEKLIRD SQGKVKPVVD KKNKKLLCGK CKTFACYTAD 900 901 IRVVEECHFT VVRDAFRECF VTKLHPRPKK FGSFDKKAKI FCARKDCLHD WGIHMKYKTF 960 961 EIPVIKIESF VVEDVATGAQ TLYAKWKDFN FEKIPFDAAE MSPWAQDLNL QGVDGLE 1017 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGCGCAGG TTGATCAGGG AGCCTGGGGG TGCCCTGCCC CTAGTTTCAG TTTCGATTTT 60 61 CCCTCCGCAG CCCGGCTTCC CCTGCAGCTC CGCCTCCGCG CTGGGCGCTC GCCTCGGCAG 120 121 ATTTCTCGCG CTTCACGGCT GTATTTAGGA AGAGCGGAGC CGAGCTCAGC GGAGCCCAGC 180 181 AGAGCGCAGG CGAAGCAGGG GGTCGCGGGG AGCGGAGCCG CAGGCATGAC GGCAGAGCAG 240 241 CGGCGGAATT TGCACGCCTT CCGCGACTAT GTCAGGAAGA TCCTGGACCC TACCTACATC 300 301 CTGAGCTACA TGACCCCCTG GTTTAGGGAC GATGTGGTGC AGCACATTCA GGCCAAGAAA 360 361 AACAACAAGG GGCCCATGGA GGCTGCCTCC CTTTTCCTCC AGGTCCTACT GGAGCTCCAG 420 421 GAGGAAGGCT GGTTCCGCGG CTTTTTGGAT GCCCTTCAAC AAGCAGGTTA TTCTGGACTT 480 481 TATGAAGCCA TTGAAAGTTG GGATTTCCAA AAACTTGAAA AATTGGAGGA GTATAGATTA 540 541 CTTTTAAAGC GTTTACAACC AGAATTTAAA ACCACAATCA ATCCAGAAGA TATCCTTCCT 600 601 GAAATATCTG GATGTTTACT TAATCAAGAA TGTGAAGAAA TTATTCAGAT AAGTTCCAAC 660 661 AAGGGGCTGA TGGCAGGTGC AGAGAAAATG GTTGAATGCC TTCTCAGATC AGACAAGGAG 720 721 AACTGGCCCA AAACTTTGAA ACTTGCATTG GAGAAAGAAG AGAGCAAGTT CAGCGAACTG 780 781 TGGATGGTAG AGAAAGGTGC AGAAAATGTT CAAATGAAAG ATCTTGAGGA TGATGAAATG 840 841 AAAACTTTGG ATGTACACAT TGTCTACAAA GAAGAACCAG AAAGCCAGAA TCTTAGCCAG 900 901 AATTCCTGTT CTTCAGAAGT GCCTCCTACT TATAGCCCAT TGAAACCAAG AAATTACCAA 960 961 CTAGAGCTGG CTTTACCTGC TCAGAAGGGA AAGAATACAA TAATATGTGC TCCTACTGGT 1020 1021 TGTGGAAAAA CCTTTGTTTC CCTTCTTATA TGCGAACATC ATCTTAAGAA ATTTCCACAA 1080 1081 GGACGAAAGG GAAAAGTTGT CGTTTTTGCT GTTCAAGTCC CACTGTATGA ACAGCAGAAA 1140 1141 TCTGTGTTCT CAGAATATTT TGAAAGATTT GGGTACAAAG TTTCAGGCAT TTCTGGAGAG 1200 1201 ACAGCTGACA ATATCTCTGT GGAACAGATT GTTGAGAACA ATGACATCAT CATTTTAACA 1260 1261 CCACAGATTC TTGTGAACAG CCTTAAAGAT GGGACTATTC CATCACTCTC CATCTTTACT 1320 1321 TTGATGATAT TTGATGAATG TCACAACACC AATAAACACC ATCCATATAA TATGATCATG 1380 1381 TTTCATTATC TGGATCAGAA ACTGGGAGGA TCTTCAGACT CATTGCCCCA GGTCATTGGG 1440 1441 CTGACTGCCT CAGTTGGCGT TGGAGATGCC AAAAACACAG CCGAAGCCAC AGAATATATC 1500 1501 TGCAAACTGT GTGCTTCTCT CGACACAGCA GTGGTAACAA CAGTCAGAGA CAACTTGGAG 1560 1561 GAACTGGAGG AGGTTGTTTA CAAGCCCCAG AAGTTTTTCA GGAAAGTGGA ATCACGGACT 1620 1621 ACAGACAGAT TTAAACGCAT CATATCTCAG CTGATGGCAG AGACAGAGGC TCTAGCAAAG 1680 1681 AGTATCTTTG AAGAACTTGG GACTGTAACT CTTGAAAACT TATCTCGAAT TCAAAATAGG 1740 1741 AATTTTGGGA CACAGAAATA TGAACAGTGG ATTATTGCAG TTCAGAAAGC ATGCATGGTG 1800 1801 TTTCAGATGC CAGACAAAGA GGAAGAAAGC AGGATTTGTA AAGCCCTGTT TTTGTACACG 1860 1861 TCACATTTGC GGAAATACAA TGATGCCCTC ATTATCAATG AGGATGCACG GATGAAAGAT 1920 1921 GCTCTGAATT ACTTGAAAAA CTTCTTCAAA AATGTCCGGG CAGCAGGATT TGATGCAATT 1980 1981 GAGCAAGATC TCACTCAGAG ATTTGAAGAA AAGCTGTTGG AACTAGAAGG TATTTCCATG 2040 2041 GATCCCAGCA ATGAGAACGC TAAACTCAAA GATCTCTGCT TCATCTTGCA AGAGGAATAC 2100 2101 CACTTAAACC CAGAGACCAG AACCATCCTC TTTGTGAAAA CCCGAGCACT GGTGGATGCC 2160 2161 TTAAAGAACT GGATTGAAGA AAATCCTAAA CTCAGCTTTC TAAAACCTGG CATATTGACT 2220 2221 GGACGTGGCA GAACAAATCA GACAATGGGA ATGACGCTCC CAGCACAGAA GTGTGCACTG 2280 2281 GATGCATTCC GAACCAACAG AGACAGCAAG ATTCTAATTG CTACCTCGGT CGCCGATGAA 2340 2341 GGCATTGACA TTGCTCAGTG CAATCTGGTC ATCCTCTACG AGTATGTGGG CAATGTCATC 2400 2401 AAAATGATCC AGACCAGAGG CAGAGGAAGA GCAAGAGGGA GCAAGTGCTT CCTTCTGACT 2460 2461 AGTAATGCTG ATGTAATCGA AAAAGAAAAA CTGAACATCT GCCAAGAAAA AATGATGAAT 2520 2521 GAGTCCATTT CAAGGCTGCA GGGATGGAAT GAAGCAGTAT TTAAGGAAAA GATTCGCCAG 2580 2581 ATACAGATTC AAGAAAAATT AATCAGGGAT AGTCAAGGAA AAGTAAAACC TGTTGTTGAT 2640 2641 AAGAAAAATA AAAAGCTGCT CTGTGGAAAG TGCAAAACCT TTGCATGTTA CACAGCTGAT 2700 2701 ATAAGAGTGG TGGAGGAATG CCATTTCACT GTGGTTAGAG ATGCTTTCAG GGAGTGCTTC 2760 2761 GTGACTAAGT TACACCCCAG ACCGAAGAAG TTTGGGAGTT TTGACAAGAA AGCTAAGATC 2820 2821 TTCTGTGCCA GGAAGGATTG CCTCCATGAC TGGGGAATTC ACATGAAGTA CAAGACATTC 2880 2881 GAGATTCCAG TTATAAAGAT CGAAAGTTTT GTGGTGGAAG ATGTTGCGAC TGGAGCTCAG 2940 2941 ACACTGTATG CAAAGTGGAA GGACTTTAAT TTTGAGAAGA TCCCATTTGA TGCTGCAGAA 3000 3001 ATGTCCCCTT GGGCTCAGGA CCTCAATCTG CAGGGAGTGG ATGGCCTTGA ATGA 3054 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Ova-3817 | Ovis aries | 92.36 | 0.0 | 1712 |
| LLPS-Fec-4391 | Felis catus | 83.71 | 0.0 | 1550 |
| LLPS-Sus-1193 | Sus scrofa | 82.82 | 0.0 | 1548 |
| LLPS-Caf-3320 | Canis familiaris | 82.63 | 0.0 | 1517 |
| LLPS-Tut-0734 | Tursiops truncatus | 82.34 | 0.0 | 1264 |
| LLPS-Urm-0161 | Ursus maritimus | 82.09 | 0.0 | 1519 |
| LLPS-Mup-3632 | Mustela putorius furo | 81.72 | 0.0 | 1357 |
| LLPS-Aim-0806 | Ailuropoda melanoleuca | 81.37 | 0.0 | 1506 |
| LLPS-Myl-3993 | Myotis lucifugus | 81.27 | 0.0 | 1496 |
| LLPS-Aon-2957 | Aotus nancymaae | 80.66 | 0.0 | 1078 |
| LLPS-Poa-0512 | Pongo abelii | 80.45 | 0.0 | 1372 |
| LLPS-Gog-3271 | Gorilla gorilla | 80.43 | 0.0 | 1468 |
| LLPS-Hos-2339 | Homo sapiens | 80.32 | 0.0 | 1466 |
| LLPS-Pat-1494 | Pan troglodytes | 80.32 | 0.0 | 1466 |
| LLPS-Pap-3092 | Pan paniscus | 80.22 | 0.0 | 1464 |
| LLPS-Eqc-0856 | Equus caballus | 80.17 | 0.0 | 1516 |
| LLPS-Loa-4177 | Loxodonta africana | 79.85 | 0.0 | 1476 |
| LLPS-Cea-3200 | Cercocebus atys | 79.78 | 0.0 | 1453 |
| LLPS-Cas-3005 | Carlito syrichta | 79.57 | 0.0 | 1442 |
| LLPS-Chs-1582 | Chlorocebus sabaeus | 79.46 | 0.0 | 1450 |
| LLPS-Caj-2968 | Callithrix jacchus | 79.46 | 0.0 | 1444 |
| LLPS-Paa-3348 | Papio anubis | 79.35 | 0.0 | 1438 |
| LLPS-Mal-0955 | Mandrillus leucophaeus | 79.25 | 0.0 | 1438 |
| LLPS-Maf-0793 | Macaca fascicularis | 79.2 | 0.0 | 1159 |
| LLPS-Man-0793 | Macaca nemestrina | 79.03 | 0.0 | 1437 |
| LLPS-Mam-2565 | Macaca mulatta | 79.03 | 0.0 | 1437 |
| LLPS-Otg-1779 | Otolemur garnettii | 78.15 | 0.0 | 1411 |
| LLPS-Rhb-3954 | Rhinopithecus bieti | 77.53 | 0.0 | 1423 |
| LLPS-Ict-2420 | Ictidomys tridecemlineatus | 75.81 | 0.0 | 1370 |
| LLPS-Fud-3346 | Fukomys damarensis | 75.05 | 0.0 | 774 |
| LLPS-Ran-2076 | Rattus norvegicus | 74.71 | 0.0 | 874 |
| LLPS-Dio-4079 | Dipodomys ordii | 74.3 | 0.0 | 1335 |
| LLPS-Orc-0658 | Oryctolagus cuniculus | 73.76 | 0.0 | 1339 |
| LLPS-Cap-4124 | Cavia porcellus | 72.58 | 0.0 | 1308 |
| LLPS-Mum-4034 | Mus musculus | 72.48 | 0.0 | 1307 |
| LLPS-Nol-3704 | Nomascus leucogenys | 72.35 | 0.0 | 825 |
| LLPS-Mea-4530 | Mesocricetus auratus | 70.68 | 0.0 | 1270 |
| LLPS-Ora-1434 | Ornithorhynchus anatinus | 60.86 | 0.0 | 978 |
| LLPS-Pes-3612 | Pelodiscus sinensis | 57.08 | 0.0 | 1019 |
| LLPS-Fia-2226 | Ficedula albicollis | 54.27 | 0.0 | 900 |
| LLPS-Anp-0658 | Anas platyrhynchos | 53.47 | 0.0 | 889 |
| LLPS-Tag-2012 | Taeniopygia guttata | 52.44 | 0.0 | 902 |
| LLPS-Lac-0434 | Latimeria chalumnae | 51.82 | 0.0 | 855 |
| LLPS-Xet-0959 | Xenopus tropicalis | 50.49 | 0.0 | 872 |
| LLPS-Leo-1524 | Lepisosteus oculatus | 47.76 | 0.0 | 811 |
| LLPS-Anc-3345 | Anolis carolinensis | 46.85 | 0.0 | 768 |
| LLPS-Scf-2686 | Scleropages formosus | 46.17 | 0.0 | 753 |
| LLPS-Asm-0834 | Astyanax mexicanus | 44.75 | 0.0 | 739 |
| LLPS-Icp-2050 | Ictalurus punctatus | 43.35 | 0.0 | 693 |
| LLPS-Mod-2497 | Monodelphis domestica | 33.88 | 1e-98 | 340 |
| LLPS-Sah-3514 | Sarcophilus harrisii | 33.1 | 8e-99 | 333 |
| LLPS-Cii-1278 | Ciona intestinalis | 32.91 | 5e-81 | 283 |
| LLPS-Pof-0689 | Poecilia formosa | 32.76 | 8e-93 | 317 |
| LLPS-Dar-2331 | Danio rerio | 32.59 | 7e-85 | 294 |
| LLPS-Ten-2049 | Tetraodon nigroviridis | 32.37 | 4e-92 | 322 |
| LLPS-Tar-0072 | Takifugu rubripes | 32.37 | 9e-86 | 297 |
| LLPS-Gaa-3051 | Gasterosteus aculeatus | 32.34 | 4e-97 | 336 |
| LLPS-Xim-0637 | Xiphophorus maculatus | 32.15 | 7e-91 | 311 |
| LLPS-Scm-1972 | Scophthalmus maximus | 31.59 | 1e-84 | 294 |
| LLPS-Cae-1093 | Caenorhabditis elegans | 29.22 | 2e-61 | 231 |
| LLPS-Met-0661 | Medicago truncatula | 28.52 | 2e-26 | 121 |
| LLPS-Brd-1618 | Brachypodium distachyon | 27.92 | 5e-35 | 149 |
| LLPS-Hea-0056 | Helianthus annuus | 27.9 | 2e-29 | 131 |
| LLPS-Sob-0158 | Sorghum bicolor | 27.85 | 2e-33 | 144 |
| LLPS-Zem-0481 | Zea mays | 27.57 | 3e-34 | 147 |
| LLPS-Mua-0985 | Musa acuminata | 27.56 | 2e-30 | 134 |
| LLPS-Sei-0339 | Setaria italica | 27.49 | 1e-35 | 151 |
| LLPS-Hov-1529 | Hordeum vulgare | 27.43 | 2e-33 | 144 |
| LLPS-Tra-2126 | Triticum aestivum | 27.43 | 1e-33 | 145 |
| LLPS-Pot-0582 | Populus trichocarpa | 27.37 | 1e-26 | 122 |
| LLPS-Gor-2038 | Gossypium raimondii | 27.32 | 6e-25 | 116 |
| LLPS-Dac-1193 | Daucus carota | 27.15 | 2e-31 | 138 |
| LLPS-Coc-1610 | Corchorus capsularis | 27.13 | 1e-31 | 138 |
| LLPS-Sol-0091 | Solanum lycopersicum | 26.82 | 8e-32 | 139 |
| LLPS-Asc-0099 | Aspergillus clavatus | 26.78 | 2e-26 | 122 |
| LLPS-Amt-1055 | Amborella trichopoda | 26.76 | 6e-32 | 139 |
| LLPS-Thc-1103 | Theobroma cacao | 26.76 | 3e-32 | 140 |
| LLPS-Nia-0174 | Nicotiana attenuata | 26.71 | 2e-33 | 144 |
| LLPS-Sem-1154 | Selaginella moellendorffii | 26.69 | 1e-31 | 138 |
| LLPS-Sot-1060 | Solanum tuberosum | 26.66 | 1e-30 | 135 |
| LLPS-Viv-1479 | Vitis vinifera | 26.61 | 2e-32 | 141 |
| LLPS-Orr-0079 | Oryza rufipogon | 26.47 | 1e-28 | 129 |
| LLPS-Orb-0705 | Oryza barthii | 26.47 | 1e-28 | 129 |
| LLPS-Ors-1283 | Oryza sativa | 26.41 | 6e-28 | 126 |
| LLPS-Phv-2173 | Phaseolus vulgaris | 26.38 | 9e-34 | 145 |
| LLPS-Gag-1261 | Gaeumannomyces graminis | 26.37 | 1e-22 | 109 |
| LLPS-Cus-0978 | Cucumis sativus | 26.35 | 3e-33 | 144 |
| LLPS-Brr-0577 | Brassica rapa | 26.31 | 2e-30 | 134 |
| LLPS-Orni-2038 | Oryza nivara | 26.31 | 8e-23 | 109 |
| LLPS-Glm-2954 | Glycine max | 26.21 | 6e-32 | 139 |
| LLPS-Via-1296 | Vigna angularis | 26.21 | 9e-33 | 142 |
| LLPS-Vir-0619 | Vigna radiata | 26.21 | 2e-32 | 141 |
| LLPS-Lem-0974 | Leptosphaeria maculans | 26.2 | 2e-25 | 118 |
| LLPS-Orp-1592 | Oryza punctata | 26.17 | 1e-28 | 129 |
| LLPS-Pug-0222 | Puccinia graminis | 26.15 | 3e-25 | 117 |
| LLPS-Php-2444 | Physcomitrella patens | 26.13 | 3e-30 | 134 |
| LLPS-Org-1819 | Oryza glaberrima | 26.12 | 8e-28 | 126 |
| LLPS-Ori-1989 | Oryza indica | 26.12 | 7e-28 | 126 |
| LLPS-Orgl-0596 | Oryza glumaepatula | 26.12 | 8e-28 | 126 |
| LLPS-Nef-0084 | Neosartorya fischeri | 26.08 | 2e-23 | 112 |
| LLPS-Mae-2108 | Manihot esculenta | 26.03 | 1e-31 | 139 |
| LLPS-Orm-0755 | Oryza meridionalis | 25.95 | 2e-27 | 125 |
| LLPS-Asfu-1300 | Aspergillus fumigatus | 25.86 | 2e-23 | 111 |
| LLPS-Bro-1355 | Brassica oleracea | 25.78 | 2e-30 | 135 |
| LLPS-Brn-1706 | Brassica napus | 25.63 | 4e-26 | 120 |
| LLPS-Lep-0703 | Leersia perrieri | 25.6 | 6e-27 | 123 |
| LLPS-Arl-0030 | Arabidopsis lyrata | 25.09 | 1e-27 | 125 |
| LLPS-Dos-1240 | Dothistroma septosporum | 25.0 | 1e-23 | 112 |
| LLPS-Mao-0204 | Magnaporthe oryzae | 24.9 | 2e-25 | 118 |
| LLPS-Pytr-0219 | Pyrenophora triticirepentis | 24.36 | 5e-23 | 110 |
| LLPS-Orbr-0238 | Oryza brachyantha | 23.91 | 2e-23 | 112 |