• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Bot-4111
DHX34

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: DExH-box helicase 34
Gene Name: DHX34
Ensembl Gene: ENSBTAG00000006848.6
Ensembl Protein: ENSBTAP00000008999.6
Organism: Bos taurus
Taxa ID: 9913
LLPS Type: Regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
P-bodyPredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MPPPRTREGR  GPWDRPRAPS  PEAAPEKWNW  NCPETRRLFE  DAFFGDEDYI  RQGSEECQKF  60
61    WTFFERLQRF  QNLKTTRKEE  KDARQPKHSH  PALADLPRAY  DPRYRINLSV  LGPDARDSRG  120
121   PGRRLPPERA  SEFRQALLHY  LDFCQKQAFG  RLAKLQRERA  ALPIAQYGHH  ILQMLKEHQV  180
181   VVVAGDTGCG  KSTQVPQYLL  AAGCSHVACT  QPRRIACISL  AKRVGFESLS  QYGSQVGYQI  240
241   RFESTRSAAT  KIVFLTVGLL  LRQMQREPSL  PQYQVLIVDE  VHERHLHNDF  LLGVLQRQLP  300
301   QRPDLKVVLM  SATINISLFS  SYFGNAPVVQ  VPGRLFPITV  VYQPQEAEPT  TSKSEKLDPR  360
361   PFLRVLEAID  NKYPPEERGD  LLVFLSGMAE  ISAVLEPAQA  YASHTQRWVV  LPLHSALSVA  420
421   DQDKVFDVAP  PGVRKCILST  NIAETSVTID  GIRFVVDSGK  VKEMSYDPQA  KLQRLQEFWI  480
481   SQASAEQRKG  RAGRTGPGVC  FRLYAESDYD  AFAPYPVPEI  RRVALDALVL  QMKSMSVGDP  540
541   RTFPFIEPPP  PTSLETAILY  LRDQGALDSS  EALTPIGSLL  AQLPVDVVIG  KMLILGSMFH  600
601   LAEPVLTIAA  ALSVQTPFTR  SAQSNPECAA  TRRPLESDQG  DPFTLLNVFN  TWVQVKSERG  660
661   RNSRKWCRHR  GIEEHRLYEM  ANLRRQFKEL  LEDHGLLAGA  QAPQPGDSYS  RLQRRRERQA  720
721   LYELKRRHEE  GVGRKRKVLR  VQDDQDGWSS  DEDRGGSASR  GAGDSVDIQD  VKFKLRHNLE  780
781   QLHAAASSAQ  ALTRDQMALL  KLVLGRGLYP  QLAVPDPFNS  SRKDSDQIFH  TQTKQGVVLH  840
841   PTCVFTNSPE  VLHAQEQAAR  GSDGSRDDRD  KMSSKHQLVT  FVSLLETNKP  YLVNCVRIPA  900
901   LQSLLLFSRS  LDTNGDCSRL  VADGWLELQL  ADTESAVRLL  AASLRLRAHW  ESALDRQLAH  960
961   QARRRLEDEE  EEEEEAPVNH  KEVAALSREL  LQFMTSKVSY  SLRRLTGLEA  QNLYVGPQTI  1020
1021  TAAPSLPGLF  GNSTPSPHPT  KGGYAVTDFL  TYNCLTSDAD  LYSDCLRTFW  TCPHCGLHMP  1080
1081  LTPLERIAHE  NTCPEAPQGG  PPGAEEAAPE  PPQKASALQK  PYHCEACQKD  FLFTPTEILR  1140
1141  HRRQHV  1146
Nucleotide CDS Sequence (FASTA)
1     ATGCCGCCTC  CCAGAACAAG  GGAGGGCAGG  GGTCCCTGGG  ACCGACCCCG  GGCTCCCAGT  60
61    CCTGAAGCGG  CCCCAGAGAA  ATGGAACTGG  AATTGTCCCG  AGACACGGCG  CCTCTTTGAG  120
121   GATGCCTTCT  TTGGCGATGA  GGATTATATC  CGGCAGGGTT  CTGAGGAGTG  TCAGAAGTTT  180
181   TGGACATTCT  TTGAACGCTT  GCAGAGGTTC  CAGAATCTCA  AGACCACCAG  GAAGGAGGAG  240
241   AAAGATGCCA  GGCAGCCCAA  GCACAGCCAC  CCAGCACTGG  CCGACTTGCC  TCGCGCCTAC  300
301   GACCCTCGCT  ACCGCATCAA  CCTCTCCGTC  CTCGGCCCGG  ACGCTCGGGA  CTCTCGGGGG  360
361   CCGGGCAGGC  GCCTGCCCCC  GGAGAGAGCG  TCCGAGTTCC  GCCAAGCCCT  GTTGCACTAC  420
421   CTGGACTTCT  GCCAGAAGCA  GGCGTTTGGG  CGACTGGCCA  AACTGCAGCG  GGAGCGGGCG  480
481   GCACTGCCCA  TTGCCCAGTA  CGGGCACCAC  ATCCTGCAGA  TGCTGAAGGA  GCACCAGGTG  540
541   GTGGTGGTGG  CGGGCGACAC  GGGCTGCGGC  AAGTCCACCC  AGGTGCCCCA  GTACCTGCTG  600
601   GCCGCCGGCT  GCAGTCACGT  GGCCTGCACC  CAGCCCCGGC  GAATCGCCTG  CATCTCACTG  660
661   GCCAAGCGCG  TTGGCTTCGA  GAGCCTCAGT  CAGTACGGCT  CACAGGTTGG  CTACCAGATT  720
721   CGTTTCGAGA  GCACGCGCTC  GGCGGCCACG  AAGATCGTGT  TCCTGACGGT  GGGGCTGCTC  780
781   CTCCGGCAGA  TGCAGCGGGA  GCCCAGCCTG  CCCCAGTACC  AGGTGCTGAT  CGTGGACGAG  840
841   GTGCATGAGC  GGCACCTCCA  CAACGACTTC  CTCCTGGGGG  TCCTCCAGCG  CCAGCTGCCC  900
901   CAGCGGCCTG  ACCTCAAGGT  TGTCCTCATG  TCGGCCACCA  TCAACATCTC  GCTCTTCTCC  960
961   AGCTACTTCG  GCAACGCCCC  CGTGGTGCAG  GTGCCGGGGC  GGCTCTTCCC  CATCACGGTC  1020
1021  GTGTACCAGC  CGCAGGAGGC  TGAGCCAACC  ACGTCCAAGT  CAGAGAAGCT  GGACCCGAGG  1080
1081  CCCTTCCTCA  GGGTGCTGGA  AGCCATCGAC  AATAAGTACC  CCCCCGAGGA  GCGGGGCGAC  1140
1141  CTCCTGGTGT  TCCTCAGCGG  CATGGCGGAG  ATCAGCGCCG  TGCTCGAGCC  CGCCCAGGCC  1200
1201  TATGCCAGCC  ACACCCAGCG  CTGGGTGGTG  CTGCCGCTGC  ACAGCGCCCT  CTCTGTGGCC  1260
1261  GACCAGGACA  AGGTATTCGA  CGTGGCCCCC  CCTGGAGTCC  GGAAATGCAT  CCTCTCCACC  1320
1321  AACATCGCTG  AGACCTCAGT  CACCATTGAC  GGGATCCGCT  TCGTGGTGGA  TTCTGGGAAG  1380
1381  GTGAAGGAGA  TGAGCTACGA  CCCACAGGCC  AAACTGCAGC  GGCTGCAGGA  GTTCTGGATC  1440
1441  AGTCAGGCCA  GTGCCGAGCA  GCGTAAGGGC  CGGGCGGGCC  GCACGGGCCC  CGGCGTCTGC  1500
1501  TTCCGCCTCT  ATGCTGAATC  GGACTATGAT  GCCTTCGCCC  CCTACCCGGT  CCCGGAGATT  1560
1561  CGGAGGGTCG  CCCTGGATGC  ATTGGTGCTT  CAGATGAAGA  GCATGAGTGT  GGGGGACCCC  1620
1621  CGAACCTTCC  CGTTCATCGA  GCCCCCACCA  CCAACCAGCT  TGGAGACAGC  CATCCTCTAC  1680
1681  CTCCGGGACC  AGGGTGCGCT  GGACAGCTCA  GAGGCCCTCA  CCCCCATTGG  GTCCCTCCTG  1740
1741  GCGCAGCTGC  CAGTGGACGT  CGTGATTGGA  AAGATGCTGA  TCCTGGGCTC  CATGTTCCAC  1800
1801  CTGGCTGAGC  CCGTGCTCAC  CATCGCCGCC  GCCCTCAGCG  TCCAGACGCC  CTTCACCCGC  1860
1861  AGCGCCCAGA  GCAACCCCGA  GTGCGCGGCG  ACGCGGCGGC  CCCTGGAGAG  TGACCAGGGT  1920
1921  GACCCCTTCA  CACTCTTGAA  CGTCTTTAAT  ACCTGGGTGC  AGGTGAAATC  TGAACGGGGC  1980
1981  AGAAACTCAC  GCAAGTGGTG  CCGCCACCGG  GGCATCGAGG  AGCACCGGCT  ATACGAGATG  2040
2041  GCCAACCTGC  GGCGCCAGTT  CAAGGAGCTG  TTGGAGGACC  ATGGGCTGCT  GGCCGGGGCC  2100
2101  CAGGCCCCGC  AGCCGGGAGA  CAGCTATAGT  CGGCTGCAGC  GGCGGCGGGA  GCGCCAGGCG  2160
2161  CTCTACGAGC  TGAAGCGCCG  GCACGAGGAG  GGCGTGGGGC  GCAAGCGCAA  AGTGCTGCGA  2220
2221  GTCCAGGACG  ACCAGGACGG  CTGGTCCAGC  GACGAGGACC  GGGGTGGCTC  AGCCTCCCGG  2280
2281  GGGGCTGGCG  ACAGCGTGGA  CATCCAGGAC  GTGAAGTTTA  AGCTCCGGCA  CAATCTGGAG  2340
2341  CAGCTGCACG  CGGCCGCCAG  CTCGGCCCAG  GCCCTGACTC  GGGACCAGAT  GGCCCTGCTC  2400
2401  AAGCTGGTGC  TCGGCCGGGG  CCTCTACCCG  CAGCTCGCCG  TCCCCGACCC  GTTTAACAGC  2460
2461  AGCCGGAAGG  ACTCGGACCA  AATCTTCCAC  ACCCAGACCA  AGCAGGGCGT  TGTGCTGCAC  2520
2521  CCCACCTGCG  TCTTCACCAA  CAGCCCTGAG  GTGCTGCACG  CGCAGGAGCA  GGCGGCCAGG  2580
2581  GGCAGCGATG  GGAGCCGAGA  TGACAGGGAC  AAGATGAGCA  GCAAGCACCA  GCTTGTCACC  2640
2641  TTCGTCTCCC  TCCTGGAGAC  CAACAAACCA  TACCTGGTGA  ACTGTGTCCG  CATTCCCGCT  2700
2701  CTACAGTCCC  TCCTGCTGTT  CAGCCGGTCC  CTGGACACCA  ATGGTGACTG  CTCCCGCCTG  2760
2761  GTGGCCGATG  GCTGGCTGGA  GCTCCAGCTC  GCAGACACTG  AGAGTGCTGT  CCGGCTCCTG  2820
2821  GCAGCTTCCC  TGCGGCTCCG  GGCCCACTGG  GAAAGCGCCC  TGGACCGGCA  GCTGGCCCAC  2880
2881  CAGGCCCGGC  GGCGGCTGGA  GGACGAAGAG  GAGGAGGAGG  AGGAAGCCCC  TGTCAACCAC  2940
2941  AAGGAGGTGG  CGGCCCTGAG  CAGGGAGCTG  CTGCAGTTCA  TGACATCCAA  GGTTTCCTAC  3000
3001  AGCCTCCGGC  GGCTCACAGG  GCTGGAAGCC  CAGAACCTCT  ATGTGGGACC  CCAGACCATC  3060
3061  ACAGCTGCCC  CCAGTCTCCC  TGGCCTCTTT  GGCAACTCTA  CCCCGTCCCC  CCACCCCACC  3120
3121  AAAGGGGGCT  ACGCAGTCAC  TGACTTCCTT  ACCTACAACT  GCCTCACGAG  CGACGCGGAC  3180
3181  CTGTACAGCG  ACTGTCTCCG  CACTTTCTGG  ACCTGCCCGC  ACTGTGGCCT  GCACATGCCC  3240
3241  CTGACGCCCC  TGGAGCGCAT  CGCCCATGAG  AACACCTGCC  CTGAGGCTCC  GCAGGGCGGC  3300
3301  CCCCCAGGGG  CTGAGGAAGC  TGCCCCCGAG  CCCCCCCAGA  AGGCATCTGC  TCTGCAGAAG  3360
3361  CCTTACCACT  GCGAGGCCTG  CCAGAAGGAC  TTTCTGTTCA  CTCCCACGGA  AATCCTGCGG  3420
3421  CACCGGAGGC  AGCACGTGTG  A  3441

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Ova-2231Ovis aries98.888e-36 151
LLPS-Myl-3686Myotis lucifugus89.370.01870
LLPS-Mal-1191Mandrillus leucophaeus89.150.01520
LLPS-Caf-3505Canis familiaris88.740.01883
LLPS-Ict-1060Ictidomys tridecemlineatus88.490.01887
LLPS-Pat-3095Pan troglodytes88.480.01874
LLPS-Mam-3355Macaca mulatta88.390.01873
LLPS-Hos-4244Homo sapiens88.390.01856
LLPS-Paa-2970Papio anubis88.310.01871
LLPS-Man-3035Macaca nemestrina88.130.01869
LLPS-Maf-4040Macaca fascicularis88.130.01868
LLPS-Aon-3161Aotus nancymaae88.050.01855
LLPS-Eqc-3574Equus caballus87.80.01824
LLPS-Otg-2873Otolemur garnettii87.710.01858
LLPS-Caj-1731Callithrix jacchus87.610.01852
LLPS-Poa-1914Pongo abelii87.520.01859
LLPS-Fec-3687Felis catus86.960.01805
LLPS-Cea-3824Cercocebus atys85.980.01796
LLPS-Rhb-2552Rhinopithecus bieti85.790.01838
LLPS-Chs-2059Chlorocebus sabaeus85.780.01797
LLPS-Mup-2155Mustela putorius furo85.770.01680
LLPS-Orc-3586Oryctolagus cuniculus85.690.01838
LLPS-Aim-3037Ailuropoda melanoleuca85.610.01801
LLPS-Mum-4485Mus musculus85.280.01833
LLPS-Ran-0591Rattus norvegicus85.210.01753
LLPS-Mea-3012Mesocricetus auratus84.760.01805
LLPS-Gog-0784Gorilla gorilla84.120.01789
LLPS-Pap-4529Pan paniscus84.040.01785
LLPS-Sus-3670Sus scrofa83.460.01500
LLPS-Cap-3640Cavia porcellus82.80.01763
LLPS-Loa-1249Loxodonta africana82.520.01760
LLPS-Dio-0083Dipodomys ordii80.170.01667
LLPS-Mod-3731Monodelphis domestica73.850.01573
LLPS-Anc-2553Anolis carolinensis66.340.01087
LLPS-Lac-0139Latimeria chalumnae64.690.01198
LLPS-Xet-3474Xenopus tropicalis62.180.01389
LLPS-Scf-1266Scleropages formosus60.880.01274
LLPS-Leo-2080Lepisosteus oculatus60.430.01270
LLPS-Pof-2673Poecilia formosa59.480.01277
LLPS-Asm-4172Astyanax mexicanus59.290.01274
LLPS-Orl-3060Oryzias latipes59.250.01251
LLPS-Xim-2955Xiphophorus maculatus59.20.01266
LLPS-Gaa-2488Gasterosteus aculeatus59.160.01265
LLPS-Orn-3471Oreochromis niloticus58.960.01249
LLPS-Dar-2694Danio rerio58.750.01263
LLPS-Scm-0966Scophthalmus maximus58.670.01264
LLPS-Ten-3441Tetraodon nigroviridis58.60.01258
LLPS-Tar-2705Takifugu rubripes57.370.01191
LLPS-Icp-3856Ictalurus punctatus56.580.01226
LLPS-Cis-0813Ciona savignyi50.230.01048
LLPS-Cii-0522Ciona intestinalis50.00.01041
LLPS-Cae-0256Caenorhabditis elegans45.250.0 639
LLPS-Drm-1125Drosophila melanogaster43.210.0 763
LLPS-Abg-0994Absidia glauca43.10.0 682
LLPS-Orgl-2328Oryza glumaepatula40.292e-104 360
LLPS-Ors-0351Oryza sativa40.117e-104 358
LLPS-Tag-1402Taeniopygia guttata39.236e-106 353
LLPS-Met-2071Medicago truncatula39.031e-105 363
LLPS-Pes-2334Pelodiscus sinensis38.792e-110 378
LLPS-Lem-0975Leptosphaeria maculans38.719e-106 367
LLPS-Scp-0981Schizosaccharomyces pombe38.625e-103 356
LLPS-Fia-0492Ficedula albicollis38.613e-109 374
LLPS-Fud-1606Fukomys damarensis38.614e-108 373
LLPS-Sah-0378Sarcophilus harrisii38.617e-109 375
LLPS-Scc-0974Schizosaccharomyces cryophilus38.571e-103 360
LLPS-Cas-3884Carlito syrichta38.431e-108 374
LLPS-Urm-0423Ursus maritimus38.437e-109 374
LLPS-Tra-2141Triticum aestivum38.387e-104 362
LLPS-Prp-1323Prunus persica38.316e-104 362
LLPS-Mae-1964Manihot esculenta38.315e-105 365
LLPS-Php-1232Physcomitrella patens38.311e-102 358
LLPS-Hea-2324Helianthus annuus38.317e-105 365
LLPS-Orbr-0461Oryza brachyantha38.283e-106 363
LLPS-Amt-1670Amborella trichopoda38.239e-107 369
LLPS-Sei-2186Setaria italica38.074e-103 349
LLPS-Coc-0598Corchorus capsularis38.055e-104 369
LLPS-Viv-2152Vitis vinifera38.052e-106 367
LLPS-Phv-0474Phaseolus vulgaris38.043e-106 368
LLPS-Via-2191Vigna angularis38.043e-106 368
LLPS-Glm-2933Glycine max38.043e-106 368
LLPS-Pot-1683Populus trichocarpa37.953e-104 363
LLPS-Thc-1578Theobroma cacao37.952e-103 359
LLPS-Org-1489Oryza glaberrima37.883e-104 362
LLPS-Orr-0026Oryza rufipogon37.885e-104 362
LLPS-Sob-1828Sorghum bicolor37.883e-104 362
LLPS-Orp-2104Oryza punctata37.886e-104 362
LLPS-Hov-0308Hordeum vulgare37.882e-104 363
LLPS-Lep-2120Leersia perrieri37.882e-104 363
LLPS-Orni-1875Oryza nivara37.885e-104 362
LLPS-Ori-2481Oryza indica37.885e-104 362
LLPS-Orb-2104Oryza barthii37.884e-104 362
LLPS-Vir-1539Vigna radiata37.864e-106 364
LLPS-Sol-0480Solanum lycopersicum37.863e-106 366
LLPS-Yal-1021Yarrowia lipolytica37.717e-106 365
LLPS-Art-0625Arabidopsis thaliana37.73e-105 364
LLPS-Brd-0498Brachypodium distachyon37.75e-103 359
LLPS-Kop-1335Komagataella pastoris37.679e-110 374
LLPS-Scj-0978Schizosaccharomyces japonicus37.561e-109 375
LLPS-Gas-0830Galdieria sulphuraria37.549e-103 356
LLPS-Sot-1017Solanum tuberosum37.59e-103 357
LLPS-Osl-1432Ostreococcus lucimarinus37.462e-107 370
LLPS-Fuv-0236Fusarium verticillioides37.411e-104 357
LLPS-Cus-1784Cucumis sativus37.353e-104 362
LLPS-Nia-0793Nicotiana attenuata37.012e-105 354
LLPS-Gor-1535Gossypium raimondii37.019e-105 353
LLPS-Orm-0574Oryza meridionalis36.71e-103 350
LLPS-Mel-0293Melampsora laricipopulina36.479e-103 347
LLPS-Dac-0105Daucus carota36.331e-102 356
LLPS-Trv-0937Trichoderma virens35.954e-103 351
LLPS-Brn-1542Brassica napus35.511e-102 356
LLPS-Trr-1132Trichoderma reesei34.026e-104 353
LLPS-Ora-0706Ornithorhynchus anatinus32.946e-104 356
LLPS-Nol-2034Nomascus leucogenys32.71e-102 354