• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Bot-0220
EXOSC5

Integrated Annotations

▼ OVERVIEW

Status: Reviewed
Protein Name: Exosome component 5
Gene Name: EXOSC5
Ensembl Gene: ENSBTAG00000016034.5
Ensembl Protein: ENSBTAP00000021338.4
Organism: Bos taurus
Taxa ID: 9913
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateDescriptionTissue/CellPMIDs
Nucleolus
"...The proteomic analysis of the MDBK cell nucleoli identified a total of 311 proteins."
MDBK cells20970743

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MEGEMQTESK  IRADSGTEPG  PRVPGCSLRH  FACEQNLLSR  PDGSASFLQG  DTSVLAGVYG  60
61    PAEVKISKEI  FNKATLEVIL  RPKTGLPGVA  EKSRERLIRN  TCEAVVLGAL  HPRTSITVVL  120
121   QVVSDAGSLL  ACCLNAACMA  LVDAGVPMRA  LFCGVTCALD  SDGTLMLDPT  AKQEKEARAV  180
181   LTFALDSVER  KLLMSTTKGL  YSDTELQQCL  AAAQTASTHV  FRFYRESLQR  RYSKS  235
Nucleotide CDS Sequence (FASTA)
1     ATGGAGGGGG  AAATGCAGAC  TGAATCGAAG  ATCCGGGCTG  ATTCTGGGAC  AGAGCCCGGC  60
61    CCTAGGGTCC  CCGGCTGTAG  CCTCCGGCAC  TTTGCCTGCG  AACAGAACTT  GCTTTCCCGG  120
121   CCTGATGGCT  CTGCCTCTTT  CCTGCAAGGG  GATACCTCTG  TCCTGGCCGG  CGTGTATGGG  180
181   CCAGCCGAGG  TGAAGATCAG  CAAAGAGATC  TTCAACAAGG  CCACGCTGGA  AGTGATCCTG  240
241   AGGCCGAAGA  CCGGACTGCC  TGGCGTAGCG  GAGAAGAGCC  GGGAGCGGCT  GATCAGAAAC  300
301   ACATGCGAAG  CGGTGGTGCT  GGGAGCGCTG  CACCCCCGCA  CCTCCATAAC  TGTGGTACTG  360
361   CAGGTCGTCA  GCGATGCTGG  CTCTCTCCTG  GCCTGTTGCC  TGAATGCCGC  CTGCATGGCC  420
421   CTGGTGGACG  CTGGTGTGCC  CATGCGGGCC  CTCTTCTGTG  GGGTCACTTG  TGCTCTGGAC  480
481   TCTGATGGGA  CCCTCATGCT  AGACCCTACT  GCTAAACAGG  AAAAGGAGGC  CCGGGCAGTC  540
541   CTGACCTTTG  CCCTTGACAG  CGTGGAAAGG  AAGCTGCTGA  TGTCCACCAC  CAAGGGGCTC  600
601   TACTCCGACA  CCGAGCTCCA  GCAGTGCCTG  GCTGCAGCCC  AGACGGCCTC  CACACACGTC  660
661   TTCCGCTTCT  ACCGGGAATC  ACTACAGAGG  CGTTACTCCA  AGAGCTGA  708

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Ova-1886Ovis aries98.32e-155 438
LLPS-Poa-0563Pongo abelii95.71e-104 307
LLPS-Tut-0256Tursiops truncatus94.042e-138 395
LLPS-Otg-1986Otolemur garnettii92.779e-137 391
LLPS-Pat-1231Pan troglodytes92.773e-136 390
LLPS-Pap-0509Pan paniscus92.773e-136 390
LLPS-Eqc-0049Equus caballus92.347e-137 391
LLPS-Fec-1502Felis catus92.341e-136 390
LLPS-Mal-0943Mandrillus leucophaeus91.912e-134 385
LLPS-Paa-1638Papio anubis91.912e-134 385
LLPS-Gog-1515Gorilla gorilla91.916e-135 386
LLPS-Maf-1135Macaca fascicularis91.912e-134 386
LLPS-Nol-0860Nomascus leucogenys91.913e-134 385
LLPS-Mam-0457Macaca mulatta91.912e-134 385
LLPS-Man-0710Macaca nemestrina91.912e-134 386
LLPS-Sus-0300Sus scrofa91.715e-123 356
LLPS-Aim-0148Ailuropoda melanoleuca91.493e-136 389
LLPS-Chs-1652Chlorocebus sabaeus91.491e-134 387
LLPS-Cea-1033Cercocebus atys91.491e-133 383
LLPS-Caf-0346Canis familiaris91.493e-133 382
LLPS-Rhb-0079Rhinopithecus bieti91.493e-134 385
LLPS-Hos-1431Homo sapiens91.496e-134 384
LLPS-Urm-0110Ursus maritimus91.261e-123 357
LLPS-Mup-0311Mustela putorius furo91.066e-134 384
LLPS-Ict-0544Ictidomys tridecemlineatus90.647e-133 381
LLPS-Dio-1375Dipodomys ordii90.182e-126 365
LLPS-Caj-2896Callithrix jacchus89.794e-130 374
LLPS-Cas-0418Carlito syrichta89.363e-131 377
LLPS-Orc-0341Oryctolagus cuniculus89.363e-140 400
LLPS-Fud-0031Fukomys damarensis88.944e-142 404
LLPS-Loa-1158Loxodonta africana88.946e-125 361
LLPS-Myl-1118Myotis lucifugus88.466e-130 374
LLPS-Mum-0444Mus musculus88.096e-130 374
LLPS-Cap-0210Cavia porcellus87.712e-137 393
LLPS-Ran-0713Rattus norvegicus87.661e-128 370
LLPS-Mea-0616Mesocricetus auratus85.123e-102 303
LLPS-Mod-1551Monodelphis domestica83.979e-130 373
LLPS-Anp-2176Anas platyrhynchos75.767e-0852.0
LLPS-Gaga-3012Gallus gallus73.482e-75 245
LLPS-Xet-2091Xenopus tropicalis72.518e-105 310
LLPS-Aon-1148Aotus nancymaae71.491e-110 323
LLPS-Fia-0123Ficedula albicollis70.532e-83 254
LLPS-Tag-1038Taeniopygia guttata69.073e-83 253
LLPS-Scm-0693Scophthalmus maximus67.466e-95 285
LLPS-Xim-0182Xiphophorus maculatus66.516e-91 276
LLPS-Orl-0967Oryzias latipes66.518e-91 274
LLPS-Orn-1709Oreochromis niloticus66.516e-92 277
LLPS-Scf-1513Scleropages formosus65.712e-93 281
LLPS-Asm-1358Astyanax mexicanus65.713e-91 275
LLPS-Tar-0941Takifugu rubripes64.797e-91 274
LLPS-Dar-0568Danio rerio64.734e-88 267
LLPS-Anc-0657Anolis carolinensis64.072e-91 275
LLPS-Gaa-1432Gasterosteus aculeatus63.987e-92 276
LLPS-Pof-1664Poecilia formosa63.811e-87 265
LLPS-Icp-1450Ictalurus punctatus63.291e-88 268
LLPS-Leo-0903Lepisosteus oculatus58.68e-74 231
LLPS-Ten-1864Tetraodon nigroviridis58.262e-85 260
LLPS-Lac-0671Latimeria chalumnae55.966e-59 191
LLPS-Chr-0159Chlamydomonas reinhardtii46.516e-31 120
LLPS-Phv-0158Phaseolus vulgaris42.119e-29 113
LLPS-Cii-0140Ciona intestinalis41.984e-46 159
LLPS-Pot-0766Populus trichocarpa40.272e-36 134
LLPS-Brn-0644Brassica napus40.098e-37 135
LLPS-Php-0973Physcomitrella patens39.555e-39 141
LLPS-Via-0541Vigna angularis39.416e-26 105
LLPS-Bro-0929Brassica oleracea39.211e-36 134
LLPS-Thc-0867Theobroma cacao39.013e-35 131
LLPS-Arl-0653Arabidopsis lyrata38.964e-37 136
LLPS-Art-0491Arabidopsis thaliana38.962e-37 137
LLPS-Spr-0211Sporisorium reilianum38.951e-1269.7
LLPS-Gor-0278Gossypium raimondii38.946e-36 133
LLPS-Viv-0530Vitis vinifera38.912e-33 126
LLPS-Brd-0904Brachypodium distachyon38.644e-33 125
LLPS-Drm-1760Drosophila melanogaster38.571e-35 132
LLPS-Cis-0862Ciona savignyi38.464e-42 149
LLPS-Mae-0140Manihot esculenta38.43e-35 131
LLPS-Sob-0166Sorghum bicolor38.292e-32 124
LLPS-Tra-1655Triticum aestivum38.181e-32 124
LLPS-Glm-2695Glycine max37.623e-33 125
LLPS-Abg-0484Absidia glauca37.041e-34 129
LLPS-Usm-0533Ustilago maydis37.043e-1474.3
LLPS-Nia-0132Nicotiana attenuata36.993e-35 131
LLPS-Prp-0806Prunus persica36.892e-34 129
LLPS-Tum-0288Tuber melanosporum36.671e-1371.2
LLPS-Sot-0101Solanum tuberosum36.52e-1370.5
LLPS-Amt-0689Amborella trichopoda36.57e-28 111
LLPS-Vir-1751Vigna radiata36.481e-23 100
LLPS-Hea-0173Helianthus annuus36.39e-1163.5
LLPS-Pytr-0102Pyrenophora triticirepentis36.092e-0753.9
LLPS-Sol-1134Solanum lycopersicum36.077e-36 132
LLPS-Orbr-1272Oryza brachyantha35.914e-32 123
LLPS-Orp-0084Oryza punctata35.774e-1164.7
LLPS-Sei-1104Setaria italica35.622e-30 119
LLPS-Hov-0514Hordeum vulgare35.572e-1062.8
LLPS-Lep-0517Leersia perrieri35.536e-31 120
LLPS-Brr-1510Brassica rapa35.469e-1266.2
LLPS-Orni-1712Oryza nivara35.454e-31 120
LLPS-Orb-0413Oryza barthii35.454e-31 120
LLPS-Ori-0316Oryza indica35.452e-31 121
LLPS-Orr-0754Oryza rufipogon35.454e-31 120
LLPS-Ors-1251Oryza sativa35.454e-31 120
LLPS-Org-0282Oryza glaberrima35.293e-31 120
LLPS-Coc-0186Corchorus capsularis35.166e-29 114
LLPS-Orm-1353Oryza meridionalis35.032e-1165.1
LLPS-Cus-0445Cucumis sativus35.022e-34 129
LLPS-Zyt-0353Zymoseptoria tritici34.943e-0856.6
LLPS-Met-0290Medicago truncatula34.814e-0958.9
LLPS-Mua-0439Musa acuminata34.814e-1062.0
LLPS-Orgl-0891Oryza glumaepatula34.393e-1164.7
LLPS-Gas-0267Galdieria sulphuraria34.215e-1987.0
LLPS-Dac-1833Daucus carota33.339e-27 109
LLPS-Osl-0641Ostreococcus lucimarinus33.175e-2090.5
LLPS-Ved-1111Verticillium dahliae32.943e-0753.5
LLPS-Asg-0631Ashbya gossypii32.843e-1884.7
LLPS-Scj-1091Schizosaccharomyces japonicus32.05e-1987.0
LLPS-Scc-0927Schizosaccharomyces cryophilus32.01e-1474.3
LLPS-Cae-0863Caenorhabditis elegans31.96e-2089.4
LLPS-Pyt-0722Pyrenophora teres31.829e-1677.8
LLPS-Sah-1855Sarcophilus harrisii31.364e-1472.8
LLPS-Dos-0154Dothistroma septosporum31.361e-1268.6
LLPS-Sem-0490Selaginella moellendorffii31.215e-0753.1
LLPS-Phn-0019Phaeosphaeria nodorum31.073e-1679.3
LLPS-Lem-0610Leptosphaeria maculans30.432e-1577.4
LLPS-Yal-0287Yarrowia lipolytica29.98e-1368.9
LLPS-Pug-0891Puccinia graminis29.758e-1472.8
LLPS-Put-0298Puccinia triticina29.644e-1473.9
LLPS-Scp-0896Schizosaccharomyces pombe29.192e-1885.1
LLPS-Miv-0706Microbotryum violaceum28.973e-1988.2
LLPS-Mao-0928Magnaporthe oryzae28.937e-1061.2
LLPS-Chc-0001Chondrus crispus28.829e-1266.6
LLPS-Asn-1130Aspergillus nidulans28.334e-0856.2
LLPS-Nec-0437Neurospora crassa27.924e-1164.7
LLPS-Ora-0879Ornithorhynchus anatinus27.273e-0856.6
LLPS-Sac-0259Saccharomyces cerevisiae26.822e-1268.2
LLPS-Mel-0397Melampsora laricipopulina25.675e-1473.6
LLPS-Gag-0012Gaeumannomyces graminis25.257e-1061.2
LLPS-Map-0315Magnaporthe poae24.757e-0958.5
LLPS-Cogr-0923Colletotrichum graminicola24.352e-1062.4
LLPS-Kop-0128Komagataella pastoris24.154e-0958.9
LLPS-Fus-0159Fusarium solani24.123e-0857.0
LLPS-Fuo-0131Fusarium oxysporum24.02e-0959.7
LLPS-Zem-0313Zea mays23.672e-1680.5
LLPS-Fuv-0385Fusarium verticillioides23.53e-0959.3
LLPS-Coo-0601Colletotrichum orbiculare22.83e-0856.6