LLPS-Art-1032
CFBP1

▼ OVERVIEW

Status: Reviewed
Protein Name: Fructose-1,6-bisphosphatase 1, chloroplastic
Gene Name: CFBP1, FBP, HCEF1, At3g54050, F24B22.10
Ensembl Gene: AT3G54050
Ensembl Protein: AT3G54050.2
Organism: Arabidopsis thaliana
Taxa ID: 3702
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateDescriptionTissue/CellPMIDs
Nucleolus
"...Comparative analysis revealed that 562 proteins were consistently identified in both experimental data sets."
3 weeks-old Arabidopsis thaliana plants29104584

▼ FUNCTION

Catalyzes the irreversible reaction from fructose-1,6-bisphosphate to fructose-6-phosphate and inorganic phosphate, to regenerate the primary CO(2) acceptor molecule, ribulose-1,5-bisphosphate (Probable). Involved in the regulation of photosynthetic electron flow and sucrose synthesis (PubMed:15448173, PubMed:20081115). Its activity is critical for normal plant development and important for the regulation of a wide range of metabolic processes (PubMed:25743161).

▼ SEQUENCE

Protein Sequence (FASTA)
1     MAATAATTTS  SHLLLSSSRH  VASSSQPSIL  SPRSLFSNNG  KRAPTGVRNH  QYASGVRCMA  60
61    VAADAAETKT  AARKKSGYEL  QTLTGWLLRQ  EMKGEIDAEL  TIVMSSISLA  CKQIASLVQR  120
121   AGISNLTGVQ  GAVNIQGEDQ  KKLDVISNEV  FSNCLRSSGR  TGIIASEEED  VPVAVEESYS  180
181   GNYVVVFDPL  DGSSNIDAAV  STGSIFGIYS  PNDECIVDDS  DDISALGSEE  QRCIVNVCQP  240
241   GNNLLAAGYC  MYSSSVIFVL  TLGKGVFSFT  LDPMYGEFVL  TQENIEIPKA  GRIYSFNEGN  300
301   YQMWDDKLKK  YIDDLKDPGP  TGKPYSARYI  GSLVGDFHRT  LLYGGIYGYP  RDAKSKNGKL  360
361   RLLYECAPMS  FIVEQAGGKG  SDGHSRVLDI  QPTEIHQRVP  LYIGSTEEVE  KLEKYLA  417
Nucleotide CDS Sequence (FASTA)
1     ATGGCAGCAA  CCGCCGCAAC  AACGACGTCG  TCTCACCTTC  TTCTCTCAAG  CTCACGTCAC  60
61    GTGGCATCAT  CATCCCAGCC  TTCAATCCTT  TCACCGAGAT  CTCTCTTCTC  CAACAACGGG  120
121   AAACGAGCAC  CAACTGGAGT  GAGGAACCAT  CAGTATGCGA  GTGGAGTGAG  GTGTATGGCC  180
181   GTAGCGGCGG  ATGCTGCTGA  GACGAAAACG  GCGGCGAGGA  AGAAGAGTGG  ATACGAACTT  240
241   CAAACGTTGA  CGGGCTGGTT  GCTGAGACAA  GAGATGAAAG  GAGAGATAGA  TGCAGAGCTG  300
301   ACGATAGTGA  TGTCGAGTAT  ATCATTGGCT  TGTAAGCAGA  TCGCTTCACT  TGTTCAACGT  360
361   GCCGGAATCT  CTAACCTGAC  CGGAGTTCAA  GGCGCCGTTA  ATATTCAGGG  AGAGGATCAG  420
421   AAGAAGCTTG  ACGTCATCTC  TAATGAGGTG  TTTTCCAACT  GTTTGAGATC  AAGTGGAAGA  480
481   ACGGGAATCA  TAGCCTCGGA  GGAAGAGGAC  GTGCCAGTTG  CGGTGGAGGA  GAGTTACTCC  540
541   GGCAACTACG  TCGTCGTGTT  TGACCCTCTT  GATGGTTCCT  CCAACATTGA  CGCTGCCGTC  600
601   TCTACTGGTT  CTATCTTCGG  TATCTATAGC  CCCAATGACG  AATGCATTGT  CGACGACTCC  660
661   GACGATATCT  CAGCTCTTGG  GTCAGAAGAA  CAAAGGTGTA  TAGTAAACGT  GTGCCAGCCA  720
721   GGGAACAACT  TGTTAGCAGC  CGGCTACTGT  ATGTACTCGA  GCTCGGTCAT  CTTCGTTCTT  780
781   ACTCTAGGCA  AAGGCGTTTT  CTCCTTCACG  CTCGATCCAA  TGTACGGTGA  GTTTGTCCTC  840
841   ACGCAAGAAA  ACATTGAGAT  CCCCAAAGCC  GGGAGAATCT  ACTCTTTCAA  CGAAGGGAAT  900
901   TACCAGATGT  GGGACGATAA  ACTAAAGAAG  TACATTGATG  ATCTTAAGGA  CCCTGGTCCA  960
961   ACTGGGAAGC  CTTACTCCGC  AAGGTACATT  GGAAGTTTGG  TTGGAGATTT  TCACAGGACT  1020
1021  TTATTGTATG  GTGGGATTTA  CGGGTACCCT  CGTGACGCAA  AGAGCAAAAA  TGGAAAACTT  1080
1081  AGGCTGTTGT  ATGAGTGTGC  ACCAATGAGT  TTCATTGTTG  AACAAGCTGG  AGGGAAAGGT  1140
1141  TCTGATGGAC  ATTCGAGAGT  ACTAGATATC  CAACCGACTG  AGATACATCA  GAGGGTTCCT  1200
1201  CTATACATTG  GAAGCACAGA  GGAAGTAGAG  AAGCTGGAGA  AGTACTTGGC  TTGA  1254

▼ KEYWORD

ID
Family
Acetylation
Calvin cycle
Carbohydrate metabolism
Chloroplast
Complete proteome
Disulfide bond
Hydrolase
Magnesium
Metal-binding
Plastid
Reference proteome
Transit peptide

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Apoplast
Cellular Component
Chloroplast
Cellular Component
Chloroplast stroma
Cellular Component
Cytoplasm
Cellular Component
Cytosol
Cellular Component
Stromule
Molecular Function
Fructose 1,6-bisphosphate 1-phosphatase activity
Molecular Function
Metal ion binding
Biological Process
Fructose 1,6-bisphosphate metabolic process
Biological Process
Fructose 6-phosphate metabolic process
Biological Process
Fructose metabolic process
Biological Process
Gluconeogenesis
Biological Process
Photosynthesis
Biological Process
Photosynthetic electron transport in photosystem I
Biological Process
Reductive pentose-phosphate cycle
Biological Process
Response to cold
Biological Process
Response to cytokinin
Biological Process
Sucrose biosynthetic process
Biological Process
Sucrose metabolic process

▼ KEGG


▼ ANNOTATION

Disorder
IUPred2A
Physicochemical
Compute pI/MwAAindex
Function
CGDB
Localization
COMPARTMENTS
Expression
ArrayExpress

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Arl-1054Arabidopsis lyrata94.030.0 685
LLPS-Bro-1491Brassica oleracea92.370.0 668
LLPS-Brr-0798Brassica rapa91.10.0 663
LLPS-Brn-2299Brassica napus91.10.0 663
LLPS-Cus-1759Cucumis sativus88.240.0 605
LLPS-Vir-1991Vigna radiata86.780.0 613
LLPS-Gor-0268Gossypium raimondii86.190.0 610
LLPS-Met-2099Medicago truncatula86.10.0 608
LLPS-Phv-2577Phaseolus vulgaris85.990.0 609
LLPS-Sot-1056Solanum tuberosum85.980.0 616
LLPS-Sol-0671Solanum lycopersicum85.980.0 618
LLPS-Mua-1455Musa acuminata85.960.0 594
LLPS-Pot-0075Populus trichocarpa85.950.0 612
LLPS-Via-0534Vigna angularis85.870.0 612
LLPS-Nia-1242Nicotiana attenuata85.790.0 616
LLPS-Amt-1382Amborella trichopoda85.380.0 591
LLPS-Glm-1538Glycine max84.720.0 617
LLPS-Thc-0447Theobroma cacao84.370.0 615
LLPS-Prp-0861Prunus persica84.050.0 605
LLPS-Coc-1047Corchorus capsularis84.00.0 614
LLPS-Dac-2034Daucus carota84.00.0 614
LLPS-Zem-1958Zea mays83.330.0 577
LLPS-Mae-1217Manihot esculenta83.240.0 608
LLPS-Viv-1689Vitis vinifera82.890.0 608
LLPS-Hea-1129Helianthus annuus82.460.0 610
LLPS-Hov-2087Hordeum vulgare82.060.0 560
LLPS-Orbr-1835Oryza brachyantha81.870.0 590
LLPS-Brd-1793Brachypodium distachyon81.870.0 566
LLPS-Tru-1726Triticum urartu81.290.0 557
LLPS-Lep-2355Leersia perrieri80.870.0 579
LLPS-Php-1211Physcomitrella patens80.590.0 560
LLPS-Sob-0850Sorghum bicolor79.840.0 573
LLPS-Orm-0926Oryza meridionalis79.630.0 592
LLPS-Ors-2163Oryza sativa79.630.0 592
LLPS-Orgl-1998Oryza glumaepatula79.630.0 592
LLPS-Ori-1859Oryza indica79.630.0 592
LLPS-Orb-0709Oryza barthii79.630.0 592
LLPS-Tra-2842Triticum aestivum79.610.0 562
LLPS-Sem-0612Selaginella moellendorffii79.410.0 560
LLPS-Sei-2074Setaria italica79.190.0 584
LLPS-Orp-2349Oryza punctata79.10.0 587
LLPS-Org-1234Oryza glaberrima77.950.0 588
LLPS-Orr-0315Oryza rufipogon77.890.0 589
LLPS-Orni-0865Oryza nivara77.890.0 589
LLPS-Chc-0773Chondrus crispus60.362e-131 391
LLPS-Gas-0676Galdieria sulphuraria58.046e-129 385
LLPS-Cym-1122Cyanidioschyzon merolae54.939e-124 371
LLPS-Usm-1052Ustilago maydis51.924e-103 317
LLPS-Miv-0977Microbotryum violaceum51.762e-111 338
LLPS-Mel-1294Melampsora laricipopulina51.764e-109 332
LLPS-Crn-1477Cryptococcus neoformans50.445e-100 309
LLPS-Spr-1326Sporisorium reilianum50.293e-105 322
LLPS-Put-0518Puccinia triticina50.01e-101 311
LLPS-Osl-1378Ostreococcus lucimarinus48.999e-106 323
LLPS-Pug-0731Puccinia graminis48.971e-104 320
LLPS-Abg-1024Absidia glauca48.774e-88 296
LLPS-Tut-2403Tursiops truncatus47.752e-78 251
LLPS-Drm-0993Drosophila melanogaster47.624e-90 283
LLPS-Nol-1901Nomascus leucogenys47.393e-76 245
LLPS-Cae-1778Caenorhabditis elegans47.21e-97 303
LLPS-Kop-0617Komagataella pastoris47.082e-95 297
LLPS-Fud-4201Fukomys damarensis47.041e-89 281
LLPS-Pof-0592Poecilia formosa46.672e-98 305
LLPS-Orn-1568Oreochromis niloticus46.392e-97 302
LLPS-Xim-3455Xiphophorus maculatus46.362e-97 302
LLPS-Mod-3790Monodelphis domestica46.296e-94 293
LLPS-Sus-2199Sus scrofa46.224e-93 291
LLPS-Ict-1879Ictidomys tridecemlineatus46.155e-93 290
LLPS-Anc-3853Anolis carolinensis46.089e-88 278
LLPS-Ten-3366Tetraodon nigroviridis46.068e-96 298
LLPS-Tar-0280Takifugu rubripes46.062e-95 296
LLPS-Orl-3100Oryzias latipes46.068e-94 292
LLPS-Ova-1086Ovis aries45.973e-92 288
LLPS-Bot-1567Bos taurus45.979e-93 290
LLPS-Cap-1549Cavia porcellus45.952e-88 278
LLPS-Ere-0078Erinaceus europaeus45.921e-89 282
LLPS-Caj-3127Callithrix jacchus45.921e-87 276
LLPS-Lac-0117Latimeria chalumnae45.811e-93 292
LLPS-Scf-4091Scleropages formosus45.768e-93 293
LLPS-Mao-0055Magnaporthe oryzae45.721e-84 269
LLPS-Gag-1564Gaeumannomyces graminis45.722e-89 281
LLPS-Mup-3596Mustela putorius furo45.673e-87 276
LLPS-Mam-4559Macaca mulatta45.622e-86 273
LLPS-Man-4015Macaca nemestrina45.622e-86 274
LLPS-Paa-3247Papio anubis45.622e-86 273
LLPS-Aon-1995Aotus nancymaae45.623e-87 276
LLPS-Chs-2847Chlorocebus sabaeus45.622e-86 273
LLPS-Scp-1332Schizosaccharomyces pombe45.61e-81 261
LLPS-Cas-0124Carlito syrichta45.561e-91 288
LLPS-Otg-1176Otolemur garnettii45.565e-93 290
LLPS-Fec-2970Felis catus45.562e-92 289
LLPS-Poa-4041Pongo abelii45.543e-87 276
LLPS-Pap-3862Pan paniscus45.543e-87 276
LLPS-Pat-4937Pan troglodytes45.543e-87 276
LLPS-Hos-4537Homo sapiens45.542e-87 276
LLPS-Gog-3975Gorilla gorilla45.543e-87 276
LLPS-Scm-0071Scophthalmus maximus45.481e-94 294
LLPS-Xet-3308Xenopus tropicalis45.431e-88 280
LLPS-Gaa-1453Gasterosteus aculeatus45.352e-96 299
LLPS-Mea-4001Mesocricetus auratus45.358e-93 290
LLPS-Yal-1114Yarrowia lipolytica45.351e-90 284
LLPS-Cea-2566Cercocebus atys45.322e-86 273
LLPS-Maf-0776Macaca fascicularis45.322e-86 274
LLPS-Aim-3220Ailuropoda melanoleuca45.271e-86 274
LLPS-Dar-2413Danio rerio45.152e-91 286
LLPS-Orc-3952Oryctolagus cuniculus44.971e-93 292
LLPS-Caf-3194Canis familiaris44.911e-92 290
LLPS-Cogr-0031Colletotrichum graminicola44.812e-87 276
LLPS-Ved-1190Verticillium dahliae44.811e-84 269
LLPS-Cog-0298Colletotrichum gloeosporioides44.817e-90 283
LLPS-Ast-1480Aspergillus terreus44.814e-88 278
LLPS-Dio-0495Dipodomys ordii44.813e-91 286
LLPS-Coo-1576Colletotrichum orbiculare44.811e-84 269
LLPS-Fuv-1393Fusarium verticillioides44.813e-88 278
LLPS-Loa-3159Loxodonta africana44.749e-92 287
LLPS-Fia-1962Ficedula albicollis44.611e-88 279
LLPS-Icp-3744Ictalurus punctatus44.554e-92 290
LLPS-Asm-2230Astyanax mexicanus44.555e-92 288
LLPS-Leo-2773Lepisosteus oculatus44.559e-93 290
LLPS-Fuo-0836Fusarium oxysporum44.518e-88 277
LLPS-Ora-3045Ornithorhynchus anatinus44.492e-48 171
LLPS-Eqc-1422Equus caballus44.441e-85 272
LLPS-Rhb-0743Rhinopithecus bieti44.442e-84 268
LLPS-Myl-3370Myotis lucifugus44.444e-88 278
LLPS-Mal-3833Mandrillus leucophaeus44.441e-84 269
LLPS-Anp-2795Anas platyrhynchos44.412e-88 280
LLPS-Ran-0460Rattus norvegicus44.382e-87 277
LLPS-Pes-0773Pelodiscus sinensis44.285e-84 267
LLPS-Map-1359Magnaporthe poae44.255e-88 278
LLPS-Phn-1457Phaeosphaeria nodorum44.213e-86 273
LLPS-Asc-1467Aspergillus clavatus44.215e-84 268
LLPS-Mum-4459Mus musculus44.081e-89 281
LLPS-Asn-1360Aspergillus nidulans43.926e-87 275
LLPS-Urm-1070Ursus maritimus43.844e-89 280
LLPS-Nec-0220Neurospora crassa43.797e-87 275
LLPS-Fus-1534Fusarium solani43.662e-87 276
LLPS-Trv-0538Trichoderma virens43.621e-86 274
LLPS-Asni-1333Aspergillus niger43.624e-86 273
LLPS-Sah-3897Sarcophilus harrisii43.455e-88 278
LLPS-Tag-3560Taeniopygia guttata43.42e-87 276
LLPS-Gaga-3644Gallus gallus43.43e-85 270
LLPS-Asfu-1441Aspergillus fumigatus43.322e-86 274
LLPS-Nef-1425Neosartorya fischeri43.324e-86 273
LLPS-Trr-1273Trichoderma reesei43.325e-86 272
LLPS-Zyt-0590Zymoseptoria tritici43.141e-70 231
LLPS-Dos-1098Dothistroma septosporum43.031e-81 261
LLPS-Lem-1349Leptosphaeria maculans43.034e-82 266
LLPS-Sac-1628Saccharomyces cerevisiae42.992e-80 258
LLPS-Pytr-1211Pyrenophora triticirepentis42.732e-84 268
LLPS-Pyt-1312Pyrenophora teres42.734e-84 268
LLPS-Blg-0012Blumeria graminis42.699e-85 269
LLPS-Tum-0929Tuber melanosporum42.482e-80 258
LLPS-Asf-1008Aspergillus flavus42.436e-83 265
LLPS-Aso-0549Aspergillus oryzae42.436e-83 265
LLPS-Asg-0026Ashbya gossypii42.43e-81 260
LLPS-Beb-1085Beauveria bassiana42.142e-83 266
LLPS-Scc-1572Schizosaccharomyces cryophilus40.625e-77 249
LLPS-Meg-2291Meleagris gallopavo36.369e-41 152