LLPS-Art-0868
RACK1A
▼ OVERVIEW
| Status: | Reviewed |
| Protein Name: | Receptor for activated C kinase 1A; Guanine nucleotide-binding protein subunit beta-like protein A; WD-40 repeat auxin-dependent protein ARCA |
| Gene Name: | RACK1A, ARCA, At1g18080, T10F20.9, T10O22.6 |
| Ensembl Gene: | AT1G18080 |
| Ensembl Protein: | AT1G18080.1 |
| Organism: | Arabidopsis thaliana |
| Taxa ID: | 3702 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Description | Tissue/Cell | PMIDs |
|---|---|---|---|
| Nucleolus | "...Comparative analysis revealed that 562 proteins were consistently identified in both experimental data sets." | 3 weeks-old Arabidopsis thaliana plants | 29104584 |
| Nucleolus | "...We identified 1602 proteins in the nucleolar and 2544 proteins in the nuclear fraction with an overlap of 1429 proteins." | Arabidopsis thaliana cells | 26980300 |
| Centrosome/Spindle pole body | Predicted from orthologs | N/A | (View) |
▼ FUNCTION
| Major component of the RACK1 regulatory proteins that play a role in multiple signal transduction pathways. Involved in multiple hormone responses and developmental processes (PubMed:16829549, PubMed:18715992, PubMed:18947417). MAPK cascade scaffolding protein involved in the protease IV and ArgC signaling pathway but not the flg22 pathway (PubMed:25731164). |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | AT1G18080.1 | AT1G18080.1 |
| UniProt | O24456, GBLPA_ARATH, C0Z2G7, Q9LDI1 | |
| GeneBank | AY063016, AC069551, AY088480, AY035007, CP002684, AC034107, AK318781, U77381 | AAF97825.1, AAF78369.1, AAB82647.1, AAM66016.1, AEE29673.1, BAH56896.1, AAL34190.1, AAK59512.1 |
| RefSeq | NM_101670.3 | NP_173248.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MAEGLVLKGT MRAHTDMVTA IATPIDNADI IVSASRDKSI ILWKLTKDDK AYGVAQRRLT 60 61 GHSHFVEDVV LSSDGQFALS GSWDGELRLW DLAAGVSTRR FVGHTKDVLS VAFSLDNRQI 120 121 VSASRDRTIK LWNTLGECKY TISEGGEGHR DWVSCVRFSP NTLQPTIVSA SWDKTVKVWN 180 181 LSNCKLRSTL AGHTGYVSTV AVSPDGSLCA SGGKDGVVLL WDLAEGKKLY SLEANSVIHA 240 241 LCFSPNRYWL CAATEHGIKI WDLESKSIVE DLKVDLKAEA EKADNSGPAA TKRKVIYCTS 300 301 LNWSADGSTL FSGYTDGVIR VWGIGRY 327 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGCGGAAG GACTCGTTTT GAAGGGCACC ATGCGTGCAC ACACTGACAT GGTGACGGCA 60 61 ATCGCCACCC CAATCGATAA CGCAGACATC ATCGTCTCAG CTTCCCGCGA CAAATCCATC 120 121 ATTTTGTGGA AACTCACCAA GGACGACAAA GCCTACGGTG TAGCTCAGAG GCGTCTCACT 180 181 GGTCACTCTC ACTTCGTTGA GGATGTTGTT CTCTCCTCCG ATGGACAATT CGCGCTTTCC 240 241 GGCAGCTGGG ACGGCGAGCT CCGTCTTTGG GATCTTGCTG CTGGTGTCTC CACTCGTAGA 300 301 TTCGTTGGAC ACACCAAGGA CGTGCTCTCC GTCGCCTTCT CACTCGACAA CCGTCAGATC 360 361 GTCTCTGCAT CTCGTGACCG TACGATCAAG CTGTGGAACA CTCTTGGTGA GTGCAAGTAC 420 421 ACCATTTCAG AAGGTGGTGA GGGACACCGT GATTGGGTTA GCTGCGTCAG ATTCAGCCCT 480 481 AACACGCTTC AGCCGACGAT TGTATCTGCT TCGTGGGACA AGACCGTGAA AGTGTGGAAC 540 541 CTTTCGAACT GCAAGCTCAG ATCGACTCTT GCTGGTCACA CCGGTTACGT GAGCACTGTG 600 601 GCTGTATCAC CTGATGGTTC TCTTTGTGCA AGTGGAGGCA AAGACGGTGT TGTTTTGCTG 660 661 TGGGATTTGG CTGAGGGGAA GAAGCTTTAC TCTCTTGAAG CTAACTCTGT GATCCATGCT 720 721 CTTTGCTTCA GTCCCAACAG GTACTGGCTC TGTGCTGCAA CTGAACATGG TATTAAGATT 780 781 TGGGACCTTG AGAGCAAGAG CATTGTTGAG GATTTGAAGG TTGATCTCAA GGCTGAGGCT 840 841 GAAAAGGCTG ACAACAGTGG TCCTGCTGCC ACCAAGAGGA AGGTTATTTA CTGCACAAGC 900 901 CTTAACTGGA GCGCTGATGG AAGCACCCTC TTCAGTGGTT ACACCGATGG AGTCATTAGA 960 961 GTTTGGGGTA TTGGTCGTTA CTAG 984 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Chloroplast | |
Cellular Component | Cytoplasm | |
Cellular Component | Cytosol | |
Cellular Component | Cytosolic ribosome | |
Cellular Component | Cytosolic small ribosomal subunit | |
Cellular Component | Nucleus | |
Cellular Component | Polysomal ribosome | |
Molecular Function | Enzyme binding | |
Molecular Function | MAP-kinase scaffold activity | |
Molecular Function | Protein kinase C binding | |
Molecular Function | Protein-containing complex scaffold activity | |
Molecular Function | Ribosome binding | |
Molecular Function | Structural constituent of ribosome | |
Biological Process | Cellular response to abscisic acid stimulus | |
Biological Process | Gibberellin mediated signaling pathway | |
Biological Process | Positive regulation of protein phosphorylation | |
Biological Process | Positive regulation of signal transduction | |
Biological Process | Regulation of translation | |
Biological Process | Rescue of stalled ribosome | |
Biological Process | Response to cadmium ion | |
Biological Process | Response to gibberellin | |
Biological Process | Response to glucose | |
Biological Process | Ribosome biogenesis | |
Biological Process | Seed germination | |
Biological Process | Vegetative to reproductive phase transition of meristem |
▼ ANNOTATION
| Disorder | ||||
| IUPred2A | ||||
| Physicochemical | ||||
| Compute pI/Mw | AAindex | |||
| Function | ||||
| iEKPD | ||||
| Localization | ||||
| COMPARTMENTS | NLSdb | |||
| Expression | ||||
| ArrayExpress | ||||
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Arl-2140 | Arabidopsis lyrata | 99.39 | 0.0 | 660 |
| LLPS-Brr-0705 | Brassica rapa | 96.94 | 0.0 | 647 |
| LLPS-Bro-1051 | Brassica oleracea | 96.04 | 0.0 | 641 |
| LLPS-Brn-1301 | Brassica napus | 87.46 | 0.0 | 590 |
| LLPS-Gor-1280 | Gossypium raimondii | 87.16 | 0.0 | 587 |
| LLPS-Glm-0639 | Glycine max | 86.24 | 0.0 | 580 |
| LLPS-Met-1097 | Medicago truncatula | 86.24 | 0.0 | 580 |
| LLPS-Mae-0426 | Manihot esculenta | 85.93 | 0.0 | 577 |
| LLPS-Thc-0167 | Theobroma cacao | 85.93 | 0.0 | 582 |
| LLPS-Pot-1579 | Populus trichocarpa | 85.63 | 0.0 | 565 |
| LLPS-Vir-0260 | Vigna radiata | 85.63 | 0.0 | 578 |
| LLPS-Viv-0656 | Vitis vinifera | 85.37 | 0.0 | 570 |
| LLPS-Prp-0259 | Prunus persica | 85.37 | 0.0 | 572 |
| LLPS-Cus-0353 | Cucumis sativus | 85.37 | 0.0 | 579 |
| LLPS-Phv-0150 | Phaseolus vulgaris | 85.32 | 0.0 | 577 |
| LLPS-Via-0238 | Vigna angularis | 84.71 | 0.0 | 571 |
| LLPS-Dac-0003 | Daucus carota | 83.64 | 0.0 | 570 |
| LLPS-Hea-0201 | Helianthus annuus | 82.93 | 0.0 | 561 |
| LLPS-Sol-0783 | Solanum lycopersicum | 82.77 | 0.0 | 553 |
| LLPS-Sot-0417 | Solanum tuberosum | 82.57 | 0.0 | 548 |
| LLPS-Nia-1599 | Nicotiana attenuata | 81.35 | 0.0 | 549 |
| LLPS-Amt-0007 | Amborella trichopoda | 75.84 | 0.0 | 523 |
| LLPS-Tru-1206 | Triticum urartu | 74.28 | 2e-146 | 424 |
| LLPS-Orp-1747 | Oryza punctata | 71.22 | 2e-168 | 479 |
| LLPS-Php-1456 | Physcomitrella patens | 71.17 | 9e-171 | 484 |
| LLPS-Brd-0502 | Brachypodium distachyon | 70.66 | 3e-167 | 476 |
| LLPS-Ors-0594 | Oryza sativa | 70.62 | 3e-168 | 479 |
| LLPS-Org-1027 | Oryza glaberrima | 70.62 | 3e-168 | 479 |
| LLPS-Zem-0486 | Zea mays | 70.62 | 1e-167 | 477 |
| LLPS-Orm-1721 | Oryza meridionalis | 70.62 | 3e-168 | 479 |
| LLPS-Orr-0242 | Oryza rufipogon | 70.62 | 3e-168 | 479 |
| LLPS-Ori-0581 | Oryza indica | 70.62 | 3e-168 | 479 |
| LLPS-Orgl-0067 | Oryza glumaepatula | 70.62 | 3e-168 | 479 |
| LLPS-Tra-1341 | Triticum aestivum | 70.24 | 3e-167 | 476 |
| LLPS-Lep-0300 | Leersia perrieri | 70.12 | 7e-168 | 478 |
| LLPS-Sob-1597 | Sorghum bicolor | 70.03 | 4e-167 | 476 |
| LLPS-Sei-0764 | Setaria italica | 69.73 | 3e-164 | 471 |
| LLPS-Hov-1565 | Hordeum vulgare | 69.55 | 8e-164 | 468 |
| LLPS-Chc-0143 | Chondrus crispus | 68.9 | 3e-159 | 455 |
| LLPS-Orni-0333 | Oryza nivara | 68.42 | 7e-167 | 475 |
| LLPS-Mua-0277 | Musa acuminata | 68.34 | 3e-160 | 457 |
| LLPS-Chr-0759 | Chlamydomonas reinhardtii | 68.2 | 1e-162 | 464 |
| LLPS-Sem-0288 | Selaginella moellendorffii | 68.09 | 7e-162 | 462 |
| LLPS-Anp-1859 | Anas platyrhynchos | 67.71 | 2e-139 | 403 |
| LLPS-Poa-3042 | Pongo abelii | 67.53 | 8e-109 | 323 |
| LLPS-Orbr-0155 | Oryza brachyantha | 67.25 | 8e-164 | 468 |
| LLPS-Osl-0039 | Ostreococcus lucimarinus | 66.77 | 3e-162 | 463 |
| LLPS-Orb-0484 | Oryza barthii | 66.77 | 4e-154 | 442 |
| LLPS-Gas-0800 | Galdieria sulphuraria | 66.67 | 1e-154 | 444 |
| LLPS-Icp-4219 | Ictalurus punctatus | 66.05 | 4e-153 | 440 |
| LLPS-Orn-2127 | Oreochromis niloticus | 65.74 | 2e-153 | 441 |
| LLPS-Abg-0147 | Absidia glauca | 65.53 | 1e-147 | 426 |
| LLPS-Xet-0179 | Xenopus tropicalis | 65.43 | 8e-153 | 439 |
| LLPS-Asm-1339 | Astyanax mexicanus | 65.43 | 1e-152 | 438 |
| LLPS-Orl-0817 | Oryzias latipes | 65.43 | 6e-153 | 439 |
| LLPS-Leo-0397 | Lepisosteus oculatus | 65.43 | 7e-152 | 437 |
| LLPS-Scf-2772 | Scleropages formosus | 65.43 | 1e-152 | 439 |
| LLPS-Otg-1218 | Otolemur garnettii | 65.12 | 3e-152 | 437 |
| LLPS-Man-1547 | Macaca nemestrina | 65.12 | 3e-152 | 437 |
| LLPS-Loa-2151 | Loxodonta africana | 65.12 | 3e-152 | 437 |
| LLPS-Dar-0523 | Danio rerio | 65.12 | 2e-151 | 436 |
| LLPS-Meg-1105 | Meleagris gallopavo | 65.12 | 3e-152 | 437 |
| LLPS-Urm-2156 | Ursus maritimus | 65.12 | 1e-151 | 438 |
| LLPS-Pap-1201 | Pan paniscus | 65.12 | 3e-152 | 437 |
| LLPS-Fec-0018 | Felis catus | 65.12 | 7e-151 | 438 |
| LLPS-Mod-1272 | Monodelphis domestica | 65.12 | 3e-152 | 437 |
| LLPS-Anc-1649 | Anolis carolinensis | 65.12 | 3e-152 | 437 |
| LLPS-Ict-1990 | Ictidomys tridecemlineatus | 65.12 | 3e-152 | 437 |
| LLPS-Gaga-0428 | Gallus gallus | 65.12 | 3e-152 | 437 |
| LLPS-Mam-0490 | Macaca mulatta | 65.12 | 5e-151 | 437 |
| LLPS-Caf-1086 | Canis familiaris | 65.12 | 3e-152 | 437 |
| LLPS-Cap-0844 | Cavia porcellus | 65.12 | 3e-152 | 437 |
| LLPS-Eqc-2390 | Equus caballus | 65.12 | 3e-152 | 437 |
| LLPS-Fud-2025 | Fukomys damarensis | 65.12 | 3e-152 | 437 |
| LLPS-Caj-1948 | Callithrix jacchus | 65.12 | 4e-151 | 438 |
| LLPS-Sus-0593 | Sus scrofa | 65.12 | 3e-152 | 437 |
| LLPS-Sah-0381 | Sarcophilus harrisii | 65.12 | 3e-152 | 437 |
| LLPS-Cea-2289 | Cercocebus atys | 65.12 | 7e-151 | 437 |
| LLPS-Aon-0358 | Aotus nancymaae | 65.12 | 3e-152 | 437 |
| LLPS-Maf-1202 | Macaca fascicularis | 65.12 | 5e-151 | 437 |
| LLPS-Mum-0164 | Mus musculus | 65.12 | 3e-152 | 437 |
| LLPS-Chs-1450 | Chlorocebus sabaeus | 65.12 | 2e-151 | 438 |
| LLPS-Ora-0221 | Ornithorhynchus anatinus | 65.12 | 3e-152 | 437 |
| LLPS-Paa-0343 | Papio anubis | 65.12 | 4e-151 | 437 |
| LLPS-Aim-1480 | Ailuropoda melanoleuca | 65.12 | 3e-152 | 437 |
| LLPS-Ova-0457 | Ovis aries | 65.12 | 3e-152 | 437 |
| LLPS-Ran-2717 | Rattus norvegicus | 65.12 | 3e-152 | 437 |
| LLPS-Dio-1735 | Dipodomys ordii | 65.12 | 3e-152 | 437 |
| LLPS-Bot-2451 | Bos taurus | 65.12 | 3e-152 | 437 |
| LLPS-Pof-0609 | Poecilia formosa | 64.81 | 1e-151 | 436 |
| LLPS-Put-0153 | Puccinia triticina | 64.81 | 6e-148 | 426 |
| LLPS-Myl-0857 | Myotis lucifugus | 64.81 | 1e-149 | 431 |
| LLPS-Xim-0653 | Xiphophorus maculatus | 64.81 | 1e-151 | 436 |
| LLPS-Gaa-0270 | Gasterosteus aculeatus | 64.29 | 5e-149 | 429 |
| LLPS-Mel-1082 | Melampsora laricipopulina | 64.2 | 5e-148 | 427 |
| LLPS-Mup-0941 | Mustela putorius furo | 64.2 | 5e-147 | 424 |
| LLPS-Scm-0380 | Scophthalmus maximus | 64.09 | 2e-147 | 426 |
| LLPS-Phn-0160 | Phaeosphaeria nodorum | 64.02 | 4e-98 | 296 |
| LLPS-Lac-1634 | Latimeria chalumnae | 63.89 | 9e-150 | 431 |
| LLPS-Crn-0610 | Cryptococcus neoformans | 63.89 | 1e-146 | 423 |
| LLPS-Rhb-1893 | Rhinopithecus bieti | 63.86 | 2e-143 | 416 |
| LLPS-Miv-0821 | Microbotryum violaceum | 63.58 | 8e-145 | 418 |
| LLPS-Ten-0607 | Tetraodon nigroviridis | 63.58 | 2e-148 | 427 |
| LLPS-Cog-0612 | Colletotrichum gloeosporioides | 63.39 | 8e-133 | 387 |
| LLPS-Drm-0452 | Drosophila melanogaster | 63.38 | 4e-144 | 417 |
| LLPS-Tar-0166 | Takifugu rubripes | 63.27 | 4e-149 | 429 |
| LLPS-Orc-2957 | Oryctolagus cuniculus | 62.96 | 3e-144 | 418 |
| LLPS-Cogr-0890 | Colletotrichum graminicola | 62.65 | 2e-145 | 420 |
| LLPS-Beb-0620 | Beauveria bassiana | 62.35 | 1e-145 | 421 |
| LLPS-Fuo-0089 | Fusarium oxysporum | 62.35 | 8e-145 | 419 |
| LLPS-Coo-0458 | Colletotrichum orbiculare | 62.35 | 4e-145 | 419 |
| LLPS-Fuv-0887 | Fusarium verticillioides | 62.35 | 8e-145 | 419 |
| LLPS-Cii-0567 | Ciona intestinalis | 62.23 | 4e-141 | 409 |
| LLPS-Fus-0338 | Fusarium solani | 62.04 | 6e-144 | 416 |
| LLPS-Ved-0834 | Verticillium dahliae | 62.04 | 5e-143 | 414 |
| LLPS-Cis-0034 | Ciona savignyi | 61.92 | 1e-140 | 408 |
| LLPS-Dos-0435 | Dothistroma septosporum | 61.73 | 2e-141 | 410 |
| LLPS-Mao-0182 | Magnaporthe oryzae | 61.73 | 3e-144 | 417 |
| LLPS-Gag-0528 | Gaeumannomyces graminis | 61.73 | 6e-144 | 416 |
| LLPS-Trr-0454 | Trichoderma reesei | 61.42 | 3e-143 | 414 |
| LLPS-Trv-0873 | Trichoderma virens | 61.42 | 2e-143 | 415 |
| LLPS-Map-0297 | Magnaporthe poae | 61.42 | 2e-143 | 415 |
| LLPS-Scs-0449 | Sclerotinia sclerotiorum | 61.42 | 3e-143 | 415 |
| LLPS-Zyt-0079 | Zymoseptoria tritici | 61.42 | 5e-141 | 409 |
| LLPS-Usm-0324 | Ustilago maydis | 61.11 | 5e-143 | 414 |
| LLPS-Nec-0104 | Neurospora crassa | 61.11 | 4e-143 | 414 |
| LLPS-Blg-0046 | Blumeria graminis | 61.11 | 4e-142 | 412 |
| LLPS-Cas-1042 | Carlito syrichta | 60.94 | 4e-131 | 383 |
| LLPS-Nef-0355 | Neosartorya fischeri | 60.8 | 4e-141 | 409 |
| LLPS-Asfu-1071 | Aspergillus fumigatus | 60.8 | 5e-141 | 409 |
| LLPS-Asn-0920 | Aspergillus nidulans | 60.8 | 4e-141 | 409 |
| LLPS-Asf-0018 | Aspergillus flavus | 60.8 | 1e-140 | 408 |
| LLPS-Aso-0265 | Aspergillus oryzae | 60.8 | 1e-140 | 408 |
| LLPS-Scj-0368 | Schizosaccharomyces japonicus | 60.74 | 2e-137 | 399 |
| LLPS-Ast-0530 | Aspergillus terreus | 60.68 | 7e-128 | 374 |
| LLPS-Mea-1069 | Mesocricetus auratus | 60.63 | 1e-87 | 270 |
| LLPS-Spr-1072 | Sporisorium reilianum | 60.49 | 5e-142 | 411 |
| LLPS-Pytr-0056 | Pyrenophora triticirepentis | 60.49 | 6e-140 | 406 |
| LLPS-Asc-0245 | Aspergillus clavatus | 60.49 | 4e-140 | 406 |
| LLPS-Pyt-0165 | Pyrenophora teres | 60.49 | 9e-140 | 405 |
| LLPS-Lem-0248 | Leptosphaeria maculans | 60.49 | 9e-140 | 405 |
| LLPS-Asni-0098 | Aspergillus niger | 59.88 | 8e-139 | 403 |
| LLPS-Cae-0078 | Caenorhabditis elegans | 59.57 | 7e-130 | 381 |
| LLPS-Scp-0099 | Schizosaccharomyces pombe | 59.51 | 4e-133 | 389 |
| LLPS-Scc-0237 | Schizosaccharomyces cryophilus | 59.2 | 2e-133 | 389 |
| LLPS-Tum-0133 | Tuber melanosporum | 58.88 | 1e-131 | 385 |
| LLPS-Yal-0222 | Yarrowia lipolytica | 57.93 | 1e-129 | 380 |
| LLPS-Cym-0253 | Cyanidioschyzon merolae | 57.1 | 4e-132 | 386 |
| LLPS-Nol-1382 | Nomascus leucogenys | 52.73 | 3e-108 | 326 |
| LLPS-Mal-1419 | Mandrillus leucophaeus | 52.48 | 1e-105 | 319 |
| LLPS-Hos-1047 | Homo sapiens | 52.08 | 8e-110 | 330 |
| LLPS-Pat-2190 | Pan troglodytes | 52.08 | 6e-110 | 330 |
| LLPS-Gog-0391 | Gorilla gorilla | 52.08 | 9e-110 | 329 |
| LLPS-Kop-0500 | Komagataella pastoris | 51.24 | 7e-103 | 311 |
| LLPS-Pug-0462 | Puccinia graminis | 49.38 | 4e-97 | 295 |
| LLPS-Asg-0045 | Ashbya gossypii | 48.62 | 6e-104 | 315 |
| LLPS-Fia-1205 | Ficedula albicollis | 48.15 | 8e-91 | 281 |
| LLPS-Sac-1038 | Saccharomyces cerevisiae | 46.63 | 1e-98 | 301 |
| LLPS-Tag-1264 | Taeniopygia guttata | 32.09 | 5e-36 | 139 |