• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Aim-3435
ESRP1

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Epithelial splicing regulatory protein 1
Gene Name: ESRP1
Ensembl Gene: ENSAMEG00000005723.1
Ensembl Protein: ENSAMEP00000006075.1
Organism: Ailuropoda melanoleuca
Taxa ID: 9646
LLPS Type: Scaffold


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Stress granulePredicted from orthologs(View)

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblENSAMET00000006325.1ENSAMEP00000006075.1
UniProtG1LGN5, G1LGN5_AILME
GeneBankACTA01033881, ACTA01041880

▼ SEQUENCE

Protein Sequence (FASTA)
1     STPLHRLPTP  LSPSPPIVMT  ASPDYLVVLF  GITAGATGAK  LGSDEKELIL  LLWKVVDLAN  60
61    KKEVGQLHEV  LVRPDQLELT  EDCKEETKID  AESLSSAPQL  DQALRQFNQS  VSNELNIGVG  120
121   TSFCLCTDGQ  LHVRQILHPE  ASKKNVLLPE  CFYSFFDLRK  EFKKCCPGSP  DIDKLDVAAM  180
181   TECLNFEKNS  SVSRYGASQV  EDMGNIILAM  ISEPYNHRFS  DPERVNYKFE  SGTCSKMELI  240
241   DDNTIVRARG  LPWQSSDQDI  ARFFKGLNIA  KGGAALCLNA  QGRRNGEALV  RFVSEEHRDL  300
301   ALQRHKHHMG  TRYIEVYKAT  GEDFLKIAGG  TSNEVAQFLS  KENQVIVRMR  GLPFTATADE  360
361   VVAFFGQHCP  ITGGKEGILF  VTYPDGRPTG  DAFVLFACEE  YAQNALRKHK  DLLGKRYIEL  420
421   FRSTAAEVQQ  VLNRFSSAPL  IPLPTPPIIP  VLPQQFVPPT  NVRDCIRLRG  LPYAATIEDI  480
481   LDFLGEFSTD  IRTHGVHMVL  NHQGRPSGDA  FIQMKSADRA  FMAAQKCHKK  TMKDRYVEVF  540
541   QCSAEEMNFV  LMGGTLNRNG  LSPPPCKLPC  LSPPSYTFPA  PTAVIPTEAA  IYQPSVLLNP  600
601   RALQPSTAYY  PAGTQLFMNY  TAYYPSPPGS  PNSLGYFPTA  ANLSGVPPQP  GTVVRMQGLA  660
661   YNTGVKEILN  FFQGYQYAAD  DGLVHTNDQA  RTLPKEWVCI  700
Nucleotide CDS Sequence (FASTA)
1     TCCACCCCAC  TTCACCGCCT  CCCAACCCCC  CTCTCCCCCT  CCCCACCTAT  CGTCATGACG  60
61    GCGTCTCCGG  ATTACTTGGT  GGTGCTTTTT  GGGATCACTG  CTGGGGCCAC  CGGGGCCAAG  120
121   CTGGGCTCGG  ATGAGAAGGA  GCTGATCCTG  CTGTTATGGA  AAGTCGTGGA  TCTGGCCAAC  180
181   AAGAAGGAGG  TGGGACAGTT  GCATGAAGTA  CTAGTTAGGC  CGGATCAGTT  GGAGCTGACG  240
241   GAGGATTGTA  AAGAAGAAAC  TAAGATCGAC  GCGGAAAGTC  TGTCCTCCGC  GCCGCAGCTG  300
301   GATCAAGCCC  TCCGACAGTT  TAACCAGTCA  GTAAGCAATG  AACTGAATAT  TGGGGTTGGA  360
361   ACCTCCTTCT  GTCTCTGTAC  TGATGGGCAG  CTTCATGTCA  GGCAAATCCT  GCATCCTGAG  420
421   GCTTCCAAGA  AGAATGTATT  ACTGCCTGAA  TGCTTCTATT  CCTTTTTTGA  CCTACGAAAA  480
481   GAATTCAAGA  AGTGTTGCCC  TGGTTCACCT  GATATTGATA  AACTGGATGT  TGCAGCAATG  540
541   ACAGAGTGCT  TAAACTTTGA  GAAGAATAGT  TCGGTCTCCC  GGTATGGAGC  CTCTCAAGTG  600
601   GAAGATATGG  GGAATATAAT  TTTAGCGATG  ATTTCAGAGC  CTTATAATCA  CAGGTTTTCA  660
661   GATCCAGAGA  GAGTAAATTA  CAAATTTGAA  AGTGGCACTT  GCAGCAAGAT  GGAACTTATT  720
721   GATGACAACA  CCATAGTCCG  GGCACGAGGT  TTACCATGGC  AGTCTTCAGA  TCAAGATATT  780
781   GCAAGATTCT  TCAAAGGACT  CAATATTGCC  AAGGGAGGTG  CAGCACTTTG  TCTGAATGCC  840
841   CAGGGTCGAA  GGAATGGAGA  AGCTCTGGTT  AGGTTTGTAA  GCGAGGAACA  CAGGGATCTA  900
901   GCATTACAGA  GGCACAAACA  TCACATGGGG  ACCCGGTACA  TTGAGGTTTA  CAAAGCAACA  960
961   GGTGAAGATT  TTCTTAAAAT  TGCTGGTGGT  ACATCCAATG  AGGTAGCCCA  GTTTCTCTCC  1020
1021  AAGGAAAATC  AAGTCATTGT  CCGCATGCGG  GGGCTCCCTT  TCACAGCCAC  AGCGGATGAA  1080
1081  GTGGTGGCCT  TCTTTGGACA  GCATTGCCCC  ATCACTGGGG  GGAAGGAAGG  CATCCTCTTT  1140
1141  GTTACCTATC  CGGATGGTAG  GCCAACGGGG  GATGCTTTTG  TCCTCTTTGC  CTGTGAAGAA  1200
1201  TATGCACAGA  ATGCATTGAG  GAAGCATAAG  GACTTGTTGG  GTAAAAGATA  CATTGAACTC  1260
1261  TTCAGGAGCA  CAGCAGCTGA  AGTCCAGCAG  GTGCTGAATC  GATTCTCATC  GGCCCCTCTT  1320
1321  ATTCCACTTC  CAACCCCTCC  CATTATTCCA  GTACTACCTC  AGCAATTCGT  GCCCCCTACA  1380
1381  AACGTTAGAG  ACTGTATACG  CCTTCGAGGT  CTTCCCTATG  CAGCCACAAT  TGAGGACATC  1440
1441  CTGGACTTTC  TGGGGGAGTT  TTCCACAGAT  ATTCGAACTC  ATGGGGTTCA  CATGGTATTG  1500
1501  AATCACCAGG  GCCGCCCATC  AGGAGATGCC  TTTATCCAGA  TGAAGTCTGC  GGACAGAGCA  1560
1561  TTTATGGCTG  CACAGAAGTG  TCATAAAAAA  ACCATGAAGG  ACAGATATGT  TGAAGTCTTT  1620
1621  CAGTGTTCAG  CTGAGGAGAT  GAACTTTGTG  TTAATGGGGG  GCACTTTAAA  TCGAAATGGC  1680
1681  TTATCCCCAC  CGCCATGTAA  GTTACCATGC  CTGTCCCCTC  CCTCCTACAC  ATTTCCAGCT  1740
1741  CCTACAGCAG  TTATTCCTAC  TGAAGCTGCC  ATTTATCAGC  CCTCTGTGCT  TTTGAATCCA  1800
1801  CGGGCACTGC  AGCCCTCTAC  CGCATACTAC  CCAGCGGGCA  CTCAGCTCTT  CATGAACTAT  1860
1861  ACTGCGTACT  ATCCCAGCCC  CCCAGGTTCG  CCCAATAGTC  TTGGCTACTT  CCCTACAGCT  1920
1921  GCTAATCTTA  GCGGTGTCCC  TCCACAGCCT  GGCACGGTGG  TCAGAATGCA  GGGCCTGGCC  1980
1981  TACAATACTG  GAGTTAAGGA  AATTCTTAAC  TTCTTCCAAG  GTTACCAGTA  TGCAGCCGAT  2040
2041  GATGGACTTG  TACACACAAA  TGACCAGGCC  AGGACTCTAC  CCAAAGAATG  GGTTTGTATT  2100
2101  TAA  2103

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Fec-3562Felis catus99.710.01338
LLPS-Urm-3212Ursus maritimus99.560.01337
LLPS-Mup-3623Mustela putorius furo99.00.01338
LLPS-Sus-2624Sus scrofa98.830.01328
LLPS-Orc-1461Oryctolagus cuniculus98.530.01322
LLPS-Eqc-3687Equus caballus98.530.01325
LLPS-Loa-1555Loxodonta africana98.390.01326
LLPS-Man-2197Macaca nemestrina98.090.01321
LLPS-Rhb-3906Rhinopithecus bieti98.090.01320
LLPS-Cas-1348Carlito syrichta98.090.01318
LLPS-Mam-4217Macaca mulatta97.950.01319
LLPS-Maf-4076Macaca fascicularis97.950.01319
LLPS-Cea-1218Cercocebus atys97.950.01319
LLPS-Dio-1414Dipodomys ordii97.950.01321
LLPS-Mal-0032Mandrillus leucophaeus97.950.01319
LLPS-Paa-1368Papio anubis97.950.01319
LLPS-Chs-3462Chlorocebus sabaeus97.880.01273
LLPS-Poa-4200Pongo abelii97.660.01319
LLPS-Pap-2405Pan paniscus97.650.01316
LLPS-Pat-2989Pan troglodytes97.650.01316
LLPS-Hos-4301Homo sapiens97.650.01316
LLPS-Mum-3097Mus musculus97.650.01315
LLPS-Gog-1256Gorilla gorilla97.510.01315
LLPS-Caj-4168Callithrix jacchus97.440.01263
LLPS-Aon-1238Aotus nancymaae97.210.01301
LLPS-Cap-0410Cavia porcellus97.070.01308
LLPS-Ran-2730Rattus norvegicus97.070.01306
LLPS-Bot-1741Bos taurus96.920.01324
LLPS-Tut-1965Tursiops truncatus96.770.01307
LLPS-Caf-4314Canis familiaris96.550.01229
LLPS-Ict-1247Ictidomys tridecemlineatus96.350.01284
LLPS-Ora-2696Ornithorhynchus anatinus94.970.0 961
LLPS-Nol-3008Nomascus leucogenys94.780.01291
LLPS-Mod-2201Monodelphis domestica94.280.01274
LLPS-Ova-3491Ovis aries93.150.01293
LLPS-Mea-3289Mesocricetus auratus92.520.01221
LLPS-Fud-2842Fukomys damarensis90.030.01211
LLPS-Myl-2612Myotis lucifugus89.10.01192
LLPS-Tag-1120Taeniopygia guttata86.990.01058
LLPS-Xet-2184Xenopus tropicalis85.320.01137
LLPS-Scf-2618Scleropages formosus74.380.01013
LLPS-Anp-0047Anas platyrhynchos68.050.0 811
LLPS-Leo-2862Lepisosteus oculatus66.810.0 876
LLPS-Gaga-2463Gallus gallus66.620.0 861
LLPS-Pes-3491Pelodiscus sinensis66.570.0 891
LLPS-Meg-0392Meleagris gallopavo65.420.0 881
LLPS-Fia-3675Ficedula albicollis65.210.0 865
LLPS-Dar-1400Danio rerio64.910.0 871
LLPS-Icp-0392Ictalurus punctatus64.830.0 844
LLPS-Lac-0514Latimeria chalumnae64.450.0 875
LLPS-Anc-2638Anolis carolinensis63.560.0 844
LLPS-Asm-2895Astyanax mexicanus63.540.0 829
LLPS-Orn-1328Oreochromis niloticus63.090.0 855
LLPS-Tar-2522Takifugu rubripes62.050.0 830
LLPS-Orl-1847Oryzias latipes61.370.0 838
LLPS-Ten-2665Tetraodon nigroviridis61.240.0 843
LLPS-Xim-1721Xiphophorus maculatus61.130.0 861
LLPS-Sah-0570Sarcophilus harrisii60.863e-153 458
LLPS-Gaa-3078Gasterosteus aculeatus60.770.0 828
LLPS-Ere-0322Erinaceus europaeus60.030.0 735
LLPS-Otg-1411Otolemur garnettii59.710.0 778
LLPS-Pof-3837Poecilia formosa58.750.0 824
LLPS-Scm-1476Scophthalmus maximus58.580.0 805
LLPS-Cis-1912Ciona savignyi47.810.0 573
LLPS-Cii-2238Ciona intestinalis46.830.0 587
LLPS-Drm-0081Drosophila melanogaster42.775e-143 449
LLPS-Cae-1723Caenorhabditis elegans41.271e-95 315
LLPS-Mua-1987Musa acuminata38.223e-31 129
LLPS-Php-0153Physcomitrella patens36.368e-0859.7
LLPS-Pot-2527Populus trichocarpa35.893e-29 122
LLPS-Glm-0826Glycine max35.244e-29 122
LLPS-Viv-1441Vitis vinifera34.931e-29 123
LLPS-Mae-1059Manihot esculenta34.931e-29 124
LLPS-Cus-1981Cucumis sativus34.621e-29 123
LLPS-Sem-0075Selaginella moellendorffii33.337e-1375.5
LLPS-Gas-1331Galdieria sulphuraria31.151e-1791.7