LLPS-Abg-1798
ABSGL_12488.1 scaffold 12955
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Mediator of RNA polymerase II transcription subunit 6; Mediator complex subunit 6 |
| Gene Name: | ABSGL_12488.1 scaffold 12955, MED6 |
| Ensembl Gene: | SAM06718 |
| Ensembl Protein: | SAM06718 |
| Organism: | Absidia glauca |
| Taxa ID: | 4829 |
| LLPS Type: | LLPS regulator |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Stress granule, Others | Predicted from orthologs | (View) |
▼ FUNCTION
| Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | SAM06718 | SAM06718 |
| UniProt | A0A168RF76, A0A168RF76_ABSGL | |
| GeneBank | LT554635 | SAM06718.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MQRSSPVEDL TSVEWRDTNW LEHVGGFQNQ HMVLEYFAMS PFWDRQSNNQ ILSMQTQYND 60 61 LRQSHEATVE ALRKMTGVEF AITHEQPPVW VIQKRYRRGP APDDVNPIAT YYIMGANIYQ 120 121 SPTIYSVIAN RLLTSLLYVN KAFKETQSVM EFHPSKGYNW KTPKEKNDKG QPNMLRAQEN 180 181 QAFRMCMDRA IDTSAISVEQ TRHSIDHQDA IISTPPSSYS ATKFQPSSSS AAAAAEALLS 240 241 DGSSKRPKKK VVEEGPGQAS TKRRKKASPS TDKQL 275 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Mediator complex | |
Molecular Function | Transcription coregulator activity | |
Biological Process | Regulation of transcription by RNA polymerase II |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Ora-2776 | Ornithorhynchus anatinus | 48.21 | 2e-10 | 62.0 |
| LLPS-Caj-1702 | Callithrix jacchus | 41.23 | 1e-19 | 89.0 |
| LLPS-Ova-1252 | Ovis aries | 40.71 | 2e-19 | 88.6 |
| LLPS-Scj-0442 | Schizosaccharomyces japonicus | 40.65 | 3e-38 | 140 |
| LLPS-Spr-0616 | Sporisorium reilianum | 38.97 | 8e-21 | 93.2 |
| LLPS-Yal-0553 | Yarrowia lipolytica | 38.75 | 1e-33 | 127 |
| LLPS-Put-0147 | Puccinia triticina | 38.67 | 5e-29 | 116 |
| LLPS-Scc-0634 | Schizosaccharomyces cryophilus | 38.56 | 2e-35 | 132 |
| LLPS-Orn-0247 | Oreochromis niloticus | 37.82 | 2e-26 | 108 |
| LLPS-Scp-0348 | Schizosaccharomyces pombe | 37.8 | 1e-33 | 127 |
| LLPS-Pes-1553 | Pelodiscus sinensis | 37.42 | 6e-27 | 110 |
| LLPS-Xim-2229 | Xiphophorus maculatus | 37.11 | 5e-25 | 105 |
| LLPS-Ict-2180 | Ictidomys tridecemlineatus | 36.93 | 2e-28 | 114 |
| LLPS-Cas-0325 | Carlito syrichta | 36.93 | 8e-29 | 115 |
| LLPS-Fud-2914 | Fukomys damarensis | 36.93 | 2e-28 | 114 |
| LLPS-Mea-0168 | Mesocricetus auratus | 36.93 | 2e-28 | 114 |
| LLPS-Kop-0032 | Komagataella pastoris | 36.78 | 9e-31 | 120 |
| LLPS-Cus-2102 | Cucumis sativus | 36.73 | 1e-22 | 98.2 |
| LLPS-Tum-0239 | Tuber melanosporum | 36.42 | 2e-18 | 87.0 |
| LLPS-Rhb-0659 | Rhinopithecus bieti | 36.36 | 4e-28 | 114 |
| LLPS-Man-2010 | Macaca nemestrina | 36.36 | 4e-28 | 114 |
| LLPS-Pat-2328 | Pan troglodytes | 36.36 | 4e-28 | 113 |
| LLPS-Pap-0983 | Pan paniscus | 36.36 | 4e-28 | 113 |
| LLPS-Urm-0495 | Ursus maritimus | 36.36 | 2e-28 | 114 |
| LLPS-Hos-0079 | Homo sapiens | 36.36 | 5e-28 | 113 |
| LLPS-Meg-0552 | Meleagris gallopavo | 36.36 | 1e-25 | 106 |
| LLPS-Nol-1884 | Nomascus leucogenys | 36.36 | 3e-28 | 114 |
| LLPS-Tag-0020 | Taeniopygia guttata | 36.36 | 7e-26 | 107 |
| LLPS-Mam-0005 | Macaca mulatta | 36.36 | 1e-27 | 113 |
| LLPS-Poa-0249 | Pongo abelii | 36.36 | 4e-28 | 113 |
| LLPS-Cap-3744 | Cavia porcellus | 36.36 | 3e-28 | 114 |
| LLPS-Gog-0378 | Gorilla gorilla | 36.36 | 5e-28 | 113 |
| LLPS-Aon-2378 | Aotus nancymaae | 36.36 | 4e-28 | 114 |
| LLPS-Cea-3825 | Cercocebus atys | 36.36 | 4e-28 | 114 |
| LLPS-Maf-1984 | Macaca fascicularis | 36.36 | 4e-28 | 114 |
| LLPS-Chs-4184 | Chlorocebus sabaeus | 36.36 | 4e-28 | 113 |
| LLPS-Mal-4397 | Mandrillus leucophaeus | 36.36 | 4e-28 | 114 |
| LLPS-Ran-1418 | Rattus norvegicus | 36.36 | 2e-28 | 114 |
| LLPS-Bot-1098 | Bos taurus | 36.21 | 7e-28 | 112 |
| LLPS-Scf-0791 | Scleropages formosus | 36.18 | 7e-25 | 104 |
| LLPS-Fia-1082 | Ficedula albicollis | 36.13 | 5e-26 | 107 |
| LLPS-Anp-0549 | Anas platyrhynchos | 36.13 | 5e-26 | 107 |
| LLPS-Gaga-2712 | Gallus gallus | 36.13 | 1e-25 | 107 |
| LLPS-Mua-1959 | Musa acuminata | 36.05 | 1e-22 | 98.6 |
| LLPS-Dac-0509 | Daucus carota | 36.05 | 2e-22 | 97.8 |
| LLPS-Sol-1045 | Solanum lycopersicum | 36.05 | 1e-20 | 92.8 |
| LLPS-Orc-2899 | Oryctolagus cuniculus | 36.0 | 7e-28 | 112 |
| LLPS-Loa-0927 | Loxodonta africana | 36.0 | 5e-28 | 112 |
| LLPS-Fec-3364 | Felis catus | 36.0 | 8e-28 | 113 |
| LLPS-Caf-2125 | Canis familiaris | 36.0 | 8e-28 | 112 |
| LLPS-Eqc-3410 | Equus caballus | 36.0 | 3e-27 | 112 |
| LLPS-Sus-2045 | Sus scrofa | 36.0 | 4e-28 | 113 |
| LLPS-Mup-3488 | Mustela putorius furo | 36.0 | 8e-28 | 112 |
| LLPS-Tut-0911 | Tursiops truncatus | 36.0 | 9e-28 | 112 |
| LLPS-Mel-1214 | Melampsora laricipopulina | 35.98 | 1e-19 | 90.5 |
| LLPS-Pof-0257 | Poecilia formosa | 35.9 | 5e-25 | 105 |
| LLPS-Php-0742 | Physcomitrella patens | 35.81 | 6e-22 | 96.7 |
| LLPS-Orm-0708 | Oryza meridionalis | 35.8 | 5e-09 | 58.2 |
| LLPS-Mum-3933 | Mus musculus | 35.8 | 1e-27 | 112 |
| LLPS-Met-1774 | Medicago truncatula | 35.62 | 1e-21 | 95.5 |
| LLPS-Icp-2514 | Ictalurus punctatus | 35.54 | 4e-27 | 109 |
| LLPS-Otg-3039 | Otolemur garnettii | 35.52 | 1e-25 | 106 |
| LLPS-Anc-3344 | Anolis carolinensis | 35.48 | 3e-25 | 105 |
| LLPS-Xet-3626 | Xenopus tropicalis | 35.48 | 9e-26 | 107 |
| LLPS-Orgl-1587 | Oryza glumaepatula | 35.44 | 4e-08 | 54.7 |
| LLPS-Mod-1988 | Monodelphis domestica | 35.43 | 3e-27 | 111 |
| LLPS-Sah-1499 | Sarcophilus harrisii | 35.43 | 4e-27 | 111 |
| LLPS-Thc-2060 | Theobroma cacao | 35.42 | 3e-21 | 94.7 |
| LLPS-Glm-1609 | Glycine max | 35.42 | 2e-21 | 95.1 |
| LLPS-Vir-0374 | Vigna radiata | 35.42 | 4e-21 | 94.0 |
| LLPS-Amt-1183 | Amborella trichopoda | 35.37 | 1e-21 | 94.4 |
| LLPS-Phv-1558 | Phaseolus vulgaris | 35.37 | 1e-21 | 95.5 |
| LLPS-Sot-1214 | Solanum tuberosum | 35.37 | 2e-20 | 92.0 |
| LLPS-Scm-0368 | Scophthalmus maximus | 35.26 | 9e-24 | 101 |
| LLPS-Dio-3545 | Dipodomys ordii | 35.23 | 2e-27 | 112 |
| LLPS-Nia-2427 | Nicotiana attenuata | 35.16 | 1e-16 | 80.1 |
| LLPS-Viv-0956 | Vitis vinifera | 34.9 | 1e-20 | 92.4 |
| LLPS-Prp-1606 | Prunus persica | 34.87 | 7e-20 | 90.5 |
| LLPS-Asm-1761 | Astyanax mexicanus | 34.84 | 7e-25 | 105 |
| LLPS-Gor-1016 | Gossypium raimondii | 34.72 | 1e-19 | 89.7 |
| LLPS-Map-1178 | Magnaporthe poae | 34.72 | 2e-14 | 74.7 |
| LLPS-Mae-0227 | Manihot esculenta | 34.69 | 6e-22 | 96.3 |
| LLPS-Art-2106 | Arabidopsis thaliana | 34.69 | 3e-21 | 95.1 |
| LLPS-Arl-0644 | Arabidopsis lyrata | 34.69 | 4e-21 | 94.0 |
| LLPS-Ten-1373 | Tetraodon nigroviridis | 34.62 | 6e-24 | 102 |
| LLPS-Aim-3163 | Ailuropoda melanoleuca | 34.62 | 3e-25 | 105 |
| LLPS-Gaa-3509 | Gasterosteus aculeatus | 34.62 | 4e-24 | 102 |
| LLPS-Tar-2869 | Takifugu rubripes | 34.62 | 1e-23 | 100 |
| LLPS-Asf-1579 | Aspergillus flavus | 34.43 | 6e-26 | 108 |
| LLPS-Aso-1119 | Aspergillus oryzae | 34.43 | 6e-26 | 108 |
| LLPS-Fuo-0631 | Fusarium oxysporum | 34.3 | 3e-21 | 95.1 |
| LLPS-Fuv-0625 | Fusarium verticillioides | 34.3 | 2e-21 | 95.5 |
| LLPS-Myl-0514 | Myotis lucifugus | 34.29 | 7e-25 | 104 |
| LLPS-Ors-1154 | Oryza sativa | 34.03 | 2e-19 | 89.0 |
| LLPS-Sob-1089 | Sorghum bicolor | 34.01 | 3e-20 | 91.7 |
| LLPS-Orp-1254 | Oryza punctata | 34.01 | 2e-19 | 89.4 |
| LLPS-Brr-1149 | Brassica rapa | 34.01 | 6e-19 | 87.8 |
| LLPS-Org-0288 | Oryza glaberrima | 34.01 | 1e-19 | 89.7 |
| LLPS-Bro-0753 | Brassica oleracea | 34.01 | 4e-19 | 88.2 |
| LLPS-Orr-1013 | Oryza rufipogon | 34.01 | 1e-19 | 89.7 |
| LLPS-Orb-0243 | Oryza barthii | 34.01 | 1e-19 | 89.7 |
| LLPS-Brn-1586 | Brassica napus | 34.01 | 4e-19 | 88.6 |
| LLPS-Ori-1320 | Oryza indica | 34.01 | 1e-19 | 89.7 |
| LLPS-Lep-0008 | Leersia perrieri | 34.01 | 2e-19 | 90.1 |
| LLPS-Pug-0052 | Puccinia graminis | 33.79 | 8e-29 | 115 |
| LLPS-Brd-0729 | Brachypodium distachyon | 33.78 | 5e-19 | 88.2 |
| LLPS-Pot-2563 | Populus trichocarpa | 33.57 | 6e-19 | 87.8 |
| LLPS-Dar-4050 | Danio rerio | 33.52 | 2e-25 | 106 |
| LLPS-Lac-3193 | Latimeria chalumnae | 33.33 | 6e-24 | 102 |
| LLPS-Tra-0727 | Triticum aestivum | 33.33 | 2e-18 | 86.3 |
| LLPS-Coo-0734 | Colletotrichum orbiculare | 33.14 | 1e-19 | 90.1 |
| LLPS-Asni-0846 | Aspergillus niger | 33.13 | 6e-21 | 94.4 |
| LLPS-Orl-0285 | Oryzias latipes | 33.12 | 2e-23 | 100 |
| LLPS-Cogr-0880 | Colletotrichum graminicola | 32.93 | 3e-19 | 89.4 |
| LLPS-Orbr-0569 | Oryza brachyantha | 32.87 | 1e-17 | 83.2 |
| LLPS-Sei-0610 | Setaria italica | 32.65 | 8e-19 | 87.4 |
| LLPS-Nef-1382 | Neosartorya fischeri | 32.62 | 2e-25 | 107 |
| LLPS-Asfu-1466 | Aspergillus fumigatus | 32.62 | 1e-25 | 107 |
| LLPS-Gas-0853 | Galdieria sulphuraria | 32.24 | 2e-13 | 70.9 |
| LLPS-Cii-0639 | Ciona intestinalis | 32.0 | 3e-15 | 74.3 |
| LLPS-Gag-0515 | Gaeumannomyces graminis | 31.98 | 4e-17 | 83.6 |
| LLPS-Trv-1155 | Trichoderma virens | 31.95 | 6e-18 | 85.5 |
| LLPS-Zem-0975 | Zea mays | 31.76 | 1e-19 | 90.1 |
| LLPS-Drm-0575 | Drosophila melanogaster | 31.61 | 4e-21 | 94.4 |
| LLPS-Hov-0948 | Hordeum vulgare | 31.47 | 1e-18 | 86.7 |
| LLPS-Trr-1142 | Trichoderma reesei | 31.36 | 8e-18 | 85.5 |
| LLPS-Cis-0534 | Ciona savignyi | 31.33 | 2e-21 | 94.7 |
| LLPS-Cae-0081 | Caenorhabditis elegans | 31.21 | 6e-18 | 84.7 |
| LLPS-Asg-1146 | Ashbya gossypii | 31.15 | 8e-25 | 104 |
| LLPS-Leo-1270 | Lepisosteus oculatus | 31.12 | 3e-25 | 105 |
| LLPS-Ast-0215 | Aspergillus terreus | 31.09 | 7e-24 | 106 |
| LLPS-Nec-1575 | Neurospora crassa | 30.57 | 4e-15 | 78.2 |
| LLPS-Sem-2277 | Selaginella moellendorffii | 30.54 | 3e-21 | 94.0 |
| LLPS-Beb-0483 | Beauveria bassiana | 30.18 | 1e-16 | 81.6 |
| LLPS-Ved-0580 | Verticillium dahliae | 30.0 | 9e-17 | 82.4 |
| LLPS-Fus-1410 | Fusarium solani | 29.85 | 2e-17 | 84.0 |
| LLPS-Asc-1319 | Aspergillus clavatus | 29.84 | 1e-20 | 93.2 |
| LLPS-Miv-0475 | Microbotryum violaceum | 29.61 | 1e-16 | 80.5 |
| LLPS-Sac-1125 | Saccharomyces cerevisiae | 29.05 | 2e-23 | 101 |
| LLPS-Usm-0075 | Ustilago maydis | 28.78 | 2e-20 | 92.4 |