※ P granule introduction P granules are the Caenorhabditis elegans ‘germ granules’, a class of perinuclear RNA granules specific to the germline (1). The defining components of P granules are two classes of RNA-binding proteins: the RGG-domain proteins, PGL-1 and PGL-3; and the DEAD-box proteins, GLH-1–4. P granules get their name from the P lineage, the embryonic lineage that gives rise to the germline. Because P granules sit on nuclear pores, most mRNAs transcribed in germ cells likely pass through a P granule on their way to the cytoplasm.
Reference
1. Wang, J.T., Seydoux, G. (2014) P granules. Curr Biol, 24(14), R637-R638. PMID: 25050955
P granule in eukaryotes (Total number, Predicted number):
1. Wang, J.T., Seydoux, G. (2014) P granules. Curr Biol, 24(14), R637-R638. PMID: 25050955
P granule in eukaryotes (Total number, Predicted number):
Caenorhabditis elegans (83, -103) |