Schizosaccharomyces pombe      TAM body


※ TAM body introduction

    Specialized structures in S.cerevisiae referred to as TAM bodies (temporal asymmetric MRP bodies) are observed exclusively during mitosis. These structures contain Xrn1p but also RNase mitochondrial RNA processing (MRP), which is an essential and highly conserved RNP complex found in eukaryotes. RNase MRP is involved in ribosome biogenesis by processing ribosomal RNA transcripts to produce primers for mitochondrial DNA replication and it cleaves S.cerevisiae B-type cyclin (CLB2) mRNA. Colocalization of Xrn1p with RNase MRP to GW/P body-like structures suggests these ribonucleases regulate mitosis by degrading mRNAs encoding cell cycle regulators (1).

Reference
1. Moser, J. J., & Fritzler, M. J. (2013) Relationship of other cytoplasmic ribonucleoprotein bodies (cRNPB) to GW/P bodies. Adv Exp Med Biol, 768, 213-242. PMID:23224973


There are 6 genes.  Reviewed (1 or Unreviewed (5

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Scp-0070
SPAC17A5.14
P40383
exo2
2
LLPS-Scp-0288
SPAC25B8.16
Q9UTA4
pop1
3
LLPS-Scp-1656
SPBC1709.20
Q7Z996
pop8
4
LLPS-Scp-0877
SPAC3A12.04c
P87120
SPAC3A12.04c
5
LLPS-Scp-0190
SPBC1703.01c
Q9P7W9
SPBC1703.01c
6
LLPS-Scp-1326
SPCC830.09c
Q9UU90
SPCC830.09c