Saccharomyces cerevisiae      TAM body


※ TAM body introduction

    Specialized structures in S.cerevisiae referred to as TAM bodies (temporal asymmetric MRP bodies) are observed exclusively during mitosis. These structures contain Xrn1p but also RNase mitochondrial RNA processing (MRP), which is an essential and highly conserved RNP complex found in eukaryotes. RNase MRP is involved in ribosome biogenesis by processing ribosomal RNA transcripts to produce primers for mitochondrial DNA replication and it cleaves S.cerevisiae B-type cyclin (CLB2) mRNA. Colocalization of Xrn1p with RNase MRP to GW/P body-like structures suggests these ribonucleases regulate mitosis by degrading mRNAs encoding cell cycle regulators (1).

Reference
1. Moser, J. J., & Fritzler, M. J. (2013) Relationship of other cytoplasmic ribonucleoprotein bodies (cRNPB) to GW/P bodies. Adv Exp Med Biol, 768, 213-242. PMID:23224973


There are 11 genes.  Reviewed (11 or Unreviewed (0

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Sac-0498
YNL221C
P41812
POP1
2
LLPS-Sac-0735
YNL282W
P53833
POP3
3
LLPS-Sac-0463
YBR257W
P38336
POP4
4
LLPS-Sac-0252
YAL033W
P28005
POP5
5
LLPS-Sac-0863
YGR030C
P53218
POP6
6
LLPS-Sac-0699
YBR167C
P38291
POP7
7
LLPS-Sac-0798
YBL018C
P38208
POP8
8
LLPS-Sac-0724
YLR145W
Q12530
RMP1
9
LLPS-Sac-0270
YHR062C
P38786
RPP1
10
LLPS-Sac-0869
YDR478W
P40993
SNM1
11
LLPS-Sac-0335
YGL173C
P22147
XRN1