Leptosphaeria maculans      TAM body


※ TAM body introduction

    Specialized structures in S.cerevisiae referred to as TAM bodies (temporal asymmetric MRP bodies) are observed exclusively during mitosis. These structures contain Xrn1p but also RNase mitochondrial RNA processing (MRP), which is an essential and highly conserved RNP complex found in eukaryotes. RNase MRP is involved in ribosome biogenesis by processing ribosomal RNA transcripts to produce primers for mitochondrial DNA replication and it cleaves S.cerevisiae B-type cyclin (CLB2) mRNA. Colocalization of Xrn1p with RNase MRP to GW/P body-like structures suggests these ribonucleases regulate mitosis by degrading mRNAs encoding cell cycle regulators (1).

Reference
1. Moser, J. J., & Fritzler, M. J. (2013) Relationship of other cytoplasmic ribonucleoprotein bodies (cRNPB) to GW/P bodies. Adv Exp Med Biol, 768, 213-242. PMID:23224973


There are 5 genes.  Reviewed (0 or Unreviewed (5

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Lem-0321
LEMA_P003600.1
E5AED4
LEMA_P003600.1
2
LLPS-Lem-0028
LEMA_P026970.1
E4ZVB9
LEMA_P026970.1
3
LLPS-Lem-1305
LEMA_P035980.1
E4ZRS7
LEMA_P035980.1
4
LLPS-Lem-0261
LEMA_P036690.1
E4ZQJ0
LEMA_P036690.1
5
LLPS-Lem-0706
LEMA_P040690.1
E4ZPE3
LEMA_P040690.1