Komagataella pastoris      TAM body


※ TAM body introduction

    Specialized structures in S.cerevisiae referred to as TAM bodies (temporal asymmetric MRP bodies) are observed exclusively during mitosis. These structures contain Xrn1p but also RNase mitochondrial RNA processing (MRP), which is an essential and highly conserved RNP complex found in eukaryotes. RNase MRP is involved in ribosome biogenesis by processing ribosomal RNA transcripts to produce primers for mitochondrial DNA replication and it cleaves S.cerevisiae B-type cyclin (CLB2) mRNA. Colocalization of Xrn1p with RNase MRP to GW/P body-like structures suggests these ribonucleases regulate mitosis by degrading mRNAs encoding cell cycle regulators (1).

Reference
1. Moser, J. J., & Fritzler, M. J. (2013) Relationship of other cytoplasmic ribonucleoprotein bodies (cRNPB) to GW/P bodies. Adv Exp Med Biol, 768, 213-242. PMID:23224973


There are 8 genes.  Reviewed (0 or Unreviewed (8

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Kop-0267
PAS_chr1-4_0176
C4QXN7
PAS_chr1-4_0176
2
LLPS-Kop-0045
PAS_chr1-4_0517
C4QYP5
PAS_chr1-4_0517
3
LLPS-Kop-0830
PAS_chr2-1_0295
C4R085
PAS_chr2-1_0295
4
LLPS-Kop-1183
PAS_chr2-1_0387
C4R0I5
PAS_chr2-1_0387
5
LLPS-Kop-0008
PAS_chr3_0432
C4R4J6
PAS_chr3_0432
6
LLPS-Kop-0832
PAS_chr3_0927
C4R600
PAS_chr3_0927
7
LLPS-Kop-1246
PAS_chr4_0566
C4R8A2
PAS_chr4_0566
8
LLPS-Kop-1221
PAS_chr4_0690
C4R8M6
PAS_chr4_0690