※ TAM body introduction

    Specialized structures in S.cerevisiae referred to as TAM bodies (temporal asymmetric MRP bodies) are observed exclusively during mitosis. These structures contain Xrn1p but also RNase mitochondrial RNA processing (MRP), which is an essential and highly conserved RNP complex found in eukaryotes. RNase MRP is involved in ribosome biogenesis by processing ribosomal RNA transcripts to produce primers for mitochondrial DNA replication and it cleaves S.cerevisiae B-type cyclin (CLB2) mRNA. Colocalization of Xrn1p with RNase MRP to GW/P body-like structures suggests these ribonucleases regulate mitosis by degrading mRNAs encoding cell cycle regulators (1).

Reference
1. Moser, J. J., & Fritzler, M. J. (2013) Relationship of other cytoplasmic ribonucleoprotein bodies (cRNPB) to GW/P bodies. Adv Exp Med Biol, 768, 213-242. PMID:23224973

  Reviewed (0)  or Unreviewed (4) 

No.	Status	DrLLPS ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		LLPS-Cas-0162	ENSTSYG00000003097.2	A0A1U7TRZ3	POP1
2		LLPS-Cas-2804	ENSTSYG00000003488.2	A0A1U7SEB3	POP4
3		LLPS-Cas-0760	ENSTSYG00000013903.2	A0A1U7TUM0	RPP30
4		LLPS-Cas-1098	ENSTSYG00000002705.2	A0A1U7U9S6	XRN1