Aspergillus fumigatus      TAM body


※ TAM body introduction

    Specialized structures in S.cerevisiae referred to as TAM bodies (temporal asymmetric MRP bodies) are observed exclusively during mitosis. These structures contain Xrn1p but also RNase mitochondrial RNA processing (MRP), which is an essential and highly conserved RNP complex found in eukaryotes. RNase MRP is involved in ribosome biogenesis by processing ribosomal RNA transcripts to produce primers for mitochondrial DNA replication and it cleaves S.cerevisiae B-type cyclin (CLB2) mRNA. Colocalization of Xrn1p with RNase MRP to GW/P body-like structures suggests these ribonucleases regulate mitosis by degrading mRNAs encoding cell cycle regulators (1).

Reference
1. Moser, J. J., & Fritzler, M. J. (2013) Relationship of other cytoplasmic ribonucleoprotein bodies (cRNPB) to GW/P bodies. Adv Exp Med Biol, 768, 213-242. PMID:23224973


There are 4 genes.  Reviewed (0 or Unreviewed (4

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Asfu-0533
AFUA_5G03120
Q4WEI4
AFUA_5G03120
2
LLPS-Asfu-0478
AFUA_5G11150
Q4WV81
AFUA_5G11150
3
LLPS-Asfu-1266
AFUA_6G02270
Q4WCS6
AFUA_6G02270
4
LLPS-Asfu-0947
AFUA_8G04820
Q4WCD4
AFUA_8G04820