Xenopus tropicalis      Sponge body


※ Sponge body introduction

    Sponge bodies are 500-3,000 nm structures which are embedded in an electron dense matrix that is free of ribosomes. Btz, Tral, Cup, eIF4E, Me31B, Yps, Gus, Dcp1/2, Sqd, BicC, Hrb27C, Bru were identified in sponge bodies with Exu-GFP indicating that these structures have a role in post-transcriptional gene regulation (1). Since sponge bodies are typical proteinaceous membrane-less organelles, liquid–liquid phase separation is shown in the formation and disassembly of sponge bodies.

Reference
1. Moser, J. J., & Fritzler, M. J. (2013) Relationship of other cytoplasmic ribonucleoprotein bodies (cRNPB) to GW/P bodies. Adv Exp Med Biol, 768, 213-242. PMID: 23224973


There are 11 genes.  Reviewed (0 or Unreviewed (11

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Xet-1788
ENSXETG00000005117.3
F7CAX7
bicc1
2
LLPS-Xet-2321
ENSXETG00000021992.3
A4IIM2
celf2
3
LLPS-Xet-0408
ENSXETG00000012190.2
Q28CH2
cpeb3
4
LLPS-Xet-2918
ENSXETG00000003704.3
F7CGX3
dazap1
5
LLPS-Xet-0079
ENSXETG00000000899.3
F7ADT1
dcp1b
6
LLPS-Xet-0263
ENSXETG00000021514.3
F6TQ63
dcp2
7
LLPS-Xet-0812
ENSXETG00000010061.3
Q0IHV9
ddx6
8
LLPS-Xet-0715
ENSXETG00000009316.3
F6ZT05
eif4e
9
LLPS-Xet-1939
ENSXETG00000012079.2
F7BV46
spsb1
10
LLPS-Xet-1722
ENSXETG00000011826.3
Q5M7M7
stau2
11
LLPS-Xet-0584
ENSXETG00000013436.3
Q28IU4
ybx1