Latimeria chalumnae      Sponge body


※ Sponge body introduction

    Sponge bodies are 500-3,000 nm structures which are embedded in an electron dense matrix that is free of ribosomes. Btz, Tral, Cup, eIF4E, Me31B, Yps, Gus, Dcp1/2, Sqd, BicC, Hrb27C, Bru were identified in sponge bodies with Exu-GFP indicating that these structures have a role in post-transcriptional gene regulation (1). Since sponge bodies are typical proteinaceous membrane-less organelles, liquid–liquid phase separation is shown in the formation and disassembly of sponge bodies.

Reference
1. Moser, J. J., & Fritzler, M. J. (2013) Relationship of other cytoplasmic ribonucleoprotein bodies (cRNPB) to GW/P bodies. Adv Exp Med Biol, 768, 213-242. PMID: 23224973


There are 12 genes.  Reviewed (0 or Unreviewed (12

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Lac-2677
ENSLACG00000013687.1
H3B0X9
2
LLPS-Lac-2156
ENSLACG00000009779.1
H3AN94
CELF2
3
LLPS-Lac-2141
ENSLACG00000010027.1
H3AP26
CPEB2
4
LLPS-Lac-1168
ENSLACG00000009693.1
H3AMZ3
DAZAP1
5
LLPS-Lac-0485
ENSLACG00000017357.1
H3BCX0
DCP1B
6
LLPS-Lac-0435
ENSLACG00000000580.1
H2ZTC9
DCP2
7
LLPS-Lac-0794
ENSLACG00000017153.2
H3BC85
DDX6
8
LLPS-Lac-1425
ENSLACG00000008977.1
H3AKL4
EIF4E
9
LLPS-Lac-1325
ENSLACG00000005306.2
H3A8K6
HNRNPD
10
LLPS-Lac-3630
ENSLACG00000013302.2
M3XHU9
SPSB4
11
LLPS-Lac-0378
ENSLACG00000016157.1
H3B8X4
STAU1
12
LLPS-Lac-0903
ENSLACG00000018135.1
H3BFG8
YBX1