Xenopus tropicalis      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 31 genes.  Reviewed (0 or Unreviewed (31

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Xet-0030
ENSXETG00000032751.1
F6XJQ2
2
LLPS-Xet-0067
ENSXETG00000034110.1
F7BRF6
3
LLPS-Xet-0463
ENSXETG00000012032.3
Q28HZ5
aurka
4
LLPS-Xet-2228
ENSXETG00000024394.3
Q28FT2
cdc6
5
LLPS-Xet-1764
ENSXETG00000020708.3
F7DBM0
ckap2
6
LLPS-Xet-2186
ENSXETG00000001986.3
F6XPY6
ckap5
7
LLPS-Xet-1589
ENSXETG00000007168.3
F6Y8T9
clta
8
LLPS-Xet-1954
ENSXETG00000015731.3
F6TQF6
dlgap5
9
LLPS-Xet-3604
ENSXETG00000023677.3
L7N3S2
dyrk3
10
LLPS-Xet-1931
ENSXETG00000015460.2
F6RPL0
fes
11
LLPS-Xet-3803
ENSXETG00000005230.3
F6VEX7
gpsm2
12
LLPS-Xet-2813
ENSXETG00000024486.3
F6ZQC4
haus6
13
LLPS-Xet-3367
ENSXETG00000013798.3
Q08D04
kat14
14
LLPS-Xet-1838
ENSXETG00000031073.1
F7D1W8
katnal1
15
LLPS-Xet-0284
ENSXETG00000012213.3
B2GU58
kif11
16
LLPS-Xet-0210
ENSXETG00000002100.3
A4QNK0
mad2l1
17
LLPS-Xet-3083
ENSXETG00000013095.3
Q28H85
mad2l2
18
LLPS-Xet-1632
ENSXETG00000020744.3
F7EB99
mapk6
19
LLPS-Xet-1310
ENSXETG00000016357.3
Q66JF3
mknk1
20
LLPS-Xet-2753
ENSXETG00000009770.3
F6Y851
msn
21
LLPS-Xet-2099
ENSXETG00000017426.3
F6ZRV4
mtor
22
LLPS-Xet-1770
ENSXETG00000000681.3
F7CM04
mtus1
23
LLPS-Xet-0678
ENSXETG00000005528.3
Q66JL0
nde1
24
LLPS-Xet-2791
ENSXETG00000012407.3
F6WUF3
pard3b
25
LLPS-Xet-0467
ENSXETG00000002271.2
Q28FM1
ranbp9
26
LLPS-Xet-0660
ENSXETG00000012166.3
A1L0Y5
sept2-B
27
LLPS-Xet-0125
ENSXETG00000018689.3
F6XZD9
smc3
28
LLPS-Xet-2818
ENSXETG00000021642.3
F6S4J7
sun1
29
LLPS-Xet-2511
ENSXETG00000023674.1
Q66JG5
tada3
30
LLPS-Xet-0303
ENSXETG00000017390.3
F6RI64
tpr
31
LLPS-Xet-2440
ENSXETG00000026635.2
F6ZA11
znf207